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Adult glioblastoma

MedGen UID:
124527
Concept ID:
C0278878
Neoplastic Process
Synonyms: Adult Glioblastoma; adult glioblastoma; adult glioblastoma multiforme; grade IV adult astrocytic neoplasm; grade IV adult astrocytic tumor; grade IV adult astrocytic tumour
 
Monarch Initiative: MONDO:0020690

Definition

A glioblastoma occurring in adults. [from NCI]

Professional guidelines

PubMed

Masood AB, Batool S, Bhatti SN, Ali A, Valko M, Jomova K, Kuca K
Front Immunol 2023;14:1202098. Epub 2023 Jul 17 doi: 10.3389/fimmu.2023.1202098. PMID: 37529045Free PMC Article
Gusyatiner O, Hegi ME
Semin Cancer Biol 2018 Aug;51:50-58. Epub 2017 Nov 21 doi: 10.1016/j.semcancer.2017.11.010. PMID: 29170066
Ahmadloo N, Kani AA, Mohammadianpanah M, Nasrolahi H, Omidvari S, Mosalaei A, Ansari M
J Egypt Natl Canc Inst 2013 Mar;25(1):21-30. Epub 2012 Dec 21 doi: 10.1016/j.jnci.2012.11.001. PMID: 23499203

Recent clinical studies

Etiology

Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, Raleigh DR, Theodosopoulos P, Aghi MK, Chang EF, Hervey-Jumper SL, Costello JF, de Groot J, Butowski NA, Clarke JL, Chang SM, Berger MS, Molinaro AM, Solomon DA
Acta Neuropathol 2023 Dec 11;147(1):3. doi: 10.1007/s00401-023-02654-1. PMID: 38079020Free PMC Article
Gestrich CK, Jajosky AN, Elliott R, Stearns D, Sadri N, Cohen ML, Couce ME
Am J Clin Pathol 2021 Mar 15;155(4):606-614. doi: 10.1093/ajcp/aqaa172. PMID: 33210143
Jones C, Karajannis MA, Jones DTW, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, Nicolaides T, Packer RJ, Persson AI, Phillips JJ, Simonds EF, Stafford JM, Tang Y, Pfister SM, Weiss WA
Neuro Oncol 2017 Feb 1;19(2):153-161. doi: 10.1093/neuonc/now101. PMID: 27282398Free PMC Article
Sturm D, Bender S, Jones DT, Lichter P, Grill J, Becher O, Hawkins C, Majewski J, Jones C, Costello JF, Iavarone A, Aldape K, Brennan CW, Jabado N, Pfister SM
Nat Rev Cancer 2014 Feb;14(2):92-107. doi: 10.1038/nrc3655. PMID: 24457416Free PMC Article
Ahmadloo N, Kani AA, Mohammadianpanah M, Nasrolahi H, Omidvari S, Mosalaei A, Ansari M
J Egypt Natl Canc Inst 2013 Mar;25(1):21-30. Epub 2012 Dec 21 doi: 10.1016/j.jnci.2012.11.001. PMID: 23499203

Diagnosis

Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, Raleigh DR, Theodosopoulos P, Aghi MK, Chang EF, Hervey-Jumper SL, Costello JF, de Groot J, Butowski NA, Clarke JL, Chang SM, Berger MS, Molinaro AM, Solomon DA
Acta Neuropathol 2023 Dec 11;147(1):3. doi: 10.1007/s00401-023-02654-1. PMID: 38079020Free PMC Article
Lechpammer M, Mahammedi A, Pomeranz Krummel DA, Sengupta S
Handb Clin Neurol 2023;192:131-140. doi: 10.1016/B978-0-323-85538-9.00011-0. PMID: 36796938
Bagley SJ, Kothari S, Rahman R, Lee EQ, Dunn GP, Galanis E, Chang SM, Nabors LB, Ahluwalia MS, Stupp R, Mehta MP, Reardon DA, Grossman SA, Sulman EP, Sampson JH, Khagi S, Weller M, Cloughesy TF, Wen PY, Khasraw M
Clin Cancer Res 2022 Feb 15;28(4):594-602. doi: 10.1158/1078-0432.CCR-21-2750. PMID: 34561269Free PMC Article
Gestrich CK, Jajosky AN, Elliott R, Stearns D, Sadri N, Cohen ML, Couce ME
Am J Clin Pathol 2021 Mar 15;155(4):606-614. doi: 10.1093/ajcp/aqaa172. PMID: 33210143
Alexander BM, Cloughesy TF
J Clin Oncol 2017 Jul 20;35(21):2402-2409. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.73.0119. PMID: 28640706

Therapy

Bagley SJ, Kothari S, Rahman R, Lee EQ, Dunn GP, Galanis E, Chang SM, Nabors LB, Ahluwalia MS, Stupp R, Mehta MP, Reardon DA, Grossman SA, Sulman EP, Sampson JH, Khagi S, Weller M, Cloughesy TF, Wen PY, Khasraw M
Clin Cancer Res 2022 Feb 15;28(4):594-602. doi: 10.1158/1078-0432.CCR-21-2750. PMID: 34561269Free PMC Article
Lu VM, Shah AH, Vallejo FA, Eichberg DG, Luther EM, Shah SS, Komotar RJ, Ivan ME
Neurosurg Focus 2021 Feb;50(2):E3. doi: 10.3171/2020.11.FOCUS20860. PMID: 33524946
Green AL, Mulcahy Levy JM, Vibhakar R, Hemenway M, Madden J, Foreman N, Dorris K
Childs Nerv Syst 2017 Jul;33(7):1043-1045. Epub 2017 May 3 doi: 10.1007/s00381-017-3431-0. PMID: 28470383
Zhang RQ, Shi Z, Chen H, Chung NY, Yin Z, Li KK, Chan DT, Poon WS, Wu J, Zhou L, Chan AK, Mao Y, Ng HK
Oncotarget 2016 Jan 26;7(4):5030-41. doi: 10.18632/oncotarget.5456. PMID: 26452024Free PMC Article
Johnson DR, O'Neill BP
J Neurooncol 2012 Apr;107(2):359-64. Epub 2011 Nov 2 doi: 10.1007/s11060-011-0749-4. PMID: 22045118

Prognosis

Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, Raleigh DR, Theodosopoulos P, Aghi MK, Chang EF, Hervey-Jumper SL, Costello JF, de Groot J, Butowski NA, Clarke JL, Chang SM, Berger MS, Molinaro AM, Solomon DA
Acta Neuropathol 2023 Dec 11;147(1):3. doi: 10.1007/s00401-023-02654-1. PMID: 38079020Free PMC Article
Njonkou R, Jackson CM, Woodworth GF, Hersh DS
Cancer Immunol Immunother 2022 Aug;71(8):1813-1822. Epub 2022 Jan 12 doi: 10.1007/s00262-021-03131-y. PMID: 35020009Free PMC Article
Gusyatiner O, Hegi ME
Semin Cancer Biol 2018 Aug;51:50-58. Epub 2017 Nov 21 doi: 10.1016/j.semcancer.2017.11.010. PMID: 29170066
Alexander BM, Cloughesy TF
J Clin Oncol 2017 Jul 20;35(21):2402-2409. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.73.0119. PMID: 28640706
Pandey R, Caflisch L, Lodi A, Brenner AJ, Tiziani S
Mol Carcinog 2017 Nov;56(11):2355-2371. Epub 2017 Jul 17 doi: 10.1002/mc.22694. PMID: 28618012Free PMC Article

Clinical prediction guides

Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, Raleigh DR, Theodosopoulos P, Aghi MK, Chang EF, Hervey-Jumper SL, Costello JF, de Groot J, Butowski NA, Clarke JL, Chang SM, Berger MS, Molinaro AM, Solomon DA
Acta Neuropathol 2023 Dec 11;147(1):3. doi: 10.1007/s00401-023-02654-1. PMID: 38079020Free PMC Article
Jiao Y, Wang M, Liu X, Wang J, Shou Y, Sun H
Childs Nerv Syst 2022 Aug;38(8):1469-1477. Epub 2022 Apr 26 doi: 10.1007/s00381-022-05522-7. PMID: 35474540
Lin GL, Nagaraja S, Filbin MG, Suvà ML, Vogel H, Monje M
Acta Neuropathol Commun 2018 Jun 28;6(1):51. doi: 10.1186/s40478-018-0553-x. PMID: 29954445Free PMC Article
Gusyatiner O, Hegi ME
Semin Cancer Biol 2018 Aug;51:50-58. Epub 2017 Nov 21 doi: 10.1016/j.semcancer.2017.11.010. PMID: 29170066
Alexander BM, Cloughesy TF
J Clin Oncol 2017 Jul 20;35(21):2402-2409. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.73.0119. PMID: 28640706

Recent systematic reviews

Gibson D, Vo AH, Lambing H, Bhattacharya P, Tahir P, Chehab FF, Butowski N
BMC Neurol 2024 Mar 23;24(1):103. doi: 10.1186/s12883-024-03605-3. PMID: 38521933Free PMC Article
Gunjur A, Balasubramanian A, Hafeez U, Menon S, Cher L, Parakh S, Gan HK
J Neurooncol 2022 Sep;159(3):539-549. Epub 2022 Aug 6 doi: 10.1007/s11060-022-04092-7. PMID: 35933567
Yuan Y, Xiang W, Qing M, Yanhui L, Jiewen L, Yunhe M
Seizure 2014 Nov;23(10):830-5. Epub 2014 Jul 8 doi: 10.1016/j.seizure.2014.06.015. PMID: 25066904

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