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adjustment disorder

MedGen UID:
1338
•Concept ID:
C0001546
•
Mental or Behavioral Dysfunction
Synonyms: Adjustment Disorder; Adjustment Disorders; Disorder, Adjustment; Disorder, Reactive; Disorders, Adjustment; Disorders, Reactive; Reactive Disorder; Reactive Disorders
SNOMED CT: Adjustment disorder (17226007); Brief situational non-psychotic disorder (192041001)
 
Monarch Initiative: MONDO:0003265

Definition

A category of psychiatric disorders which are characterized by emotional or behavioral symptoms that develop within 3 months of a stressor and do not persist for more than an additional 6 months after the stressor is no longer present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVadjustment disorder

Professional guidelines

PubMed

Adjustment Disorder: Diagnosis and Treatment in Primary Care.
Geer K
Prim Care 2023 Mar;50(1):83-88. Epub 2023 Jan 10 doi: 10.1016/j.pop.2022.10.006. PMID: 36822730
Evaluation and Management of SCI-Associated Pain.
Saulino M, Averna JF
Curr Pain Headache Rep 2016 Sep;20(9):53. doi: 10.1007/s11916-016-0587-3. PMID: 27474095
Adjustment disorder: epidemiology, diagnosis and treatment.
Casey P
CNS Drugs 2009 Nov;23(11):927-38. doi: 10.2165/11311000-000000000-00000. PMID: 19845414

Recent clinical studies

Etiology

Outcomes and prognosis of adjustment disorder in adults: A systematic review.
Morgan MA, Kelber MS, Bellanti DM, Beech EH, Boyd C, Galloway L, Ojha S, Garvey Wilson AL, Otto J, Belsher BE
J Psychiatr Res 2022 Dec;156:498-510. Epub 2022 Nov 1 doi: 10.1016/j.jpsychires.2022.10.052. PMID: 36347110
Post-traumatic stress disorder and cancer.
Cordova MJ, Riba MB, Spiegel D
Lancet Psychiatry 2017 Apr;4(4):330-338. Epub 2017 Jan 19 doi: 10.1016/S2215-0366(17)30014-7. PMID: 28109647Free PMC Article
Depression and cardiovascular disease: a clinical review.
Hare DL, Toukhsati SR, Johansson P, Jaarsma T
Eur Heart J 2014 Jun 1;35(21):1365-72. Epub 2013 Nov 25 doi: 10.1093/eurheartj/eht462. PMID: 24282187
Adjustment disorder: epidemiology, diagnosis and treatment.
Casey P
CNS Drugs 2009 Nov;23(11):927-38. doi: 10.2165/11311000-000000000-00000. PMID: 19845414
Cancer and depression.
Spiegel D
Br J Psychiatry Suppl 1996 Jun;(30):109-16. PMID: 8864156

Diagnosis

Adjustment Disorder: Diagnosis and Treatment in Primary Care.
Geer K
Prim Care 2023 Mar;50(1):83-88. Epub 2023 Jan 10 doi: 10.1016/j.pop.2022.10.006. PMID: 36822730
Adjustment Disorder: Current Developments and Future Directions.
O'Donnell ML, Agathos JA, Metcalf O, Gibson K, Lau W
Int J Environ Res Public Health 2019 Jul 16;16(14) doi: 10.3390/ijerph16142537. PMID: 31315203Free PMC Article
Post-traumatic stress disorder and cancer.
Cordova MJ, Riba MB, Spiegel D
Lancet Psychiatry 2017 Apr;4(4):330-338. Epub 2017 Jan 19 doi: 10.1016/S2215-0366(17)30014-7. PMID: 28109647Free PMC Article
Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies.
Mitchell AJ, Chan M, Bhatti H, Halton M, Grassi L, Johansen C, Meader N
Lancet Oncol 2011 Feb;12(2):160-74. Epub 2011 Jan 19 doi: 10.1016/S1470-2045(11)70002-X. PMID: 21251875
Adjustment disorder: epidemiology, diagnosis and treatment.
Casey P
CNS Drugs 2009 Nov;23(11):927-38. doi: 10.2165/11311000-000000000-00000. PMID: 19845414

Therapy

Isotretinoin and the risk of psychiatric disturbances: A global study shedding new light on a debatable story.
Kridin K, Ludwig RJ
J Am Acad Dermatol 2023 Feb;88(2):388-394. Epub 2022 Oct 20 doi: 10.1016/j.jaad.2022.10.031. PMID: 36273659
Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.
Anagha K, Shihabudheen P, Uvais NA
Prim Care Companion CNS Disord 2021 Jul 29;23(4) doi: 10.4088/PCC.20m02747. PMID: 34324797
Pharmacotherapy of adjustment disorder: A review.
Stein DJ
World J Biol Psychiatry 2018;19(sup1):S46-S52. doi: 10.1080/15622975.2018.1492736. PMID: 30204560
Association of Stress-Related Disorders With Subsequent Autoimmune Disease.
Song H, Fang F, Tomasson G, Arnberg FK, Mataix-Cols D, Fernández de la Cruz L, Almqvist C, Fall K, Valdimarsdóttir UA
JAMA 2018 Jun 19;319(23):2388-2400. doi: 10.1001/jama.2018.7028. PMID: 29922828Free PMC Article
Depression and cardiovascular disease: a clinical review.
Hare DL, Toukhsati SR, Johansson P, Jaarsma T
Eur Heart J 2014 Jun 1;35(21):1365-72. Epub 2013 Nov 25 doi: 10.1093/eurheartj/eht462. PMID: 24282187

Prognosis

Adjustment Disorder: Current Developments and Future Directions.
O'Donnell ML, Agathos JA, Metcalf O, Gibson K, Lau W
Int J Environ Res Public Health 2019 Jul 16;16(14) doi: 10.3390/ijerph16142537. PMID: 31315203Free PMC Article
Association of Stress-Related Disorders With Subsequent Autoimmune Disease.
Song H, Fang F, Tomasson G, Arnberg FK, Mataix-Cols D, Fernández de la Cruz L, Almqvist C, Fall K, Valdimarsdóttir UA
JAMA 2018 Jun 19;319(23):2388-2400. doi: 10.1001/jama.2018.7028. PMID: 29922828Free PMC Article
Post-traumatic stress disorder and cancer.
Cordova MJ, Riba MB, Spiegel D
Lancet Psychiatry 2017 Apr;4(4):330-338. Epub 2017 Jan 19 doi: 10.1016/S2215-0366(17)30014-7. PMID: 28109647Free PMC Article
Depression and cardiovascular disease: a clinical review.
Hare DL, Toukhsati SR, Johansson P, Jaarsma T
Eur Heart J 2014 Jun 1;35(21):1365-72. Epub 2013 Nov 25 doi: 10.1093/eurheartj/eht462. PMID: 24282187
Adjustment disorder: epidemiology, diagnosis and treatment.
Casey P
CNS Drugs 2009 Nov;23(11):927-38. doi: 10.2165/11311000-000000000-00000. PMID: 19845414

Clinical prediction guides

Outcomes and prognosis of adjustment disorder in adults: A systematic review.
Morgan MA, Kelber MS, Bellanti DM, Beech EH, Boyd C, Galloway L, Ojha S, Garvey Wilson AL, Otto J, Belsher BE
J Psychiatr Res 2022 Dec;156:498-510. Epub 2022 Nov 1 doi: 10.1016/j.jpsychires.2022.10.052. PMID: 36347110
Validation of the International Adjustment Disorder Questionnaire in Israel and Switzerland.
Levin Y, Bachem R, Hyland P, Karatzias T, Shevlin M, Ben-Ezra M, Maercker A
Clin Psychol Psychother 2022 Jul;29(4):1321-1330. Epub 2022 Jan 20 doi: 10.1002/cpp.2710. PMID: 35018693
Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.
Anagha K, Shihabudheen P, Uvais NA
Prim Care Companion CNS Disord 2021 Jul 29;23(4) doi: 10.4088/PCC.20m02747. PMID: 34324797
Post-traumatic stress disorder and cancer.
Cordova MJ, Riba MB, Spiegel D
Lancet Psychiatry 2017 Apr;4(4):330-338. Epub 2017 Jan 19 doi: 10.1016/S2215-0366(17)30014-7. PMID: 28109647Free PMC Article
Cancer and depression.
Spiegel D
Br J Psychiatry Suppl 1996 Jun;(30):109-16. PMID: 8864156

Recent systematic reviews

Technology-supported treatments for adjustment disorder: A systematic review and preliminary meta-analysis.
Fernández-Buendía S, Miguel C, Dumarkaite A, Kazlauskas E, Cuijpers P, Quero S
J Affect Disord 2024 Feb 15;347:29-38. Epub 2023 Nov 20 doi: 10.1016/j.jad.2023.11.059. PMID: 37992766
Antidepressants for the treatment of depression in people with cancer.
Vita G, Compri B, Matcham F, Barbui C, Ostuzzi G
Cochrane Database Syst Rev 2023 Mar 31;3(3):CD011006. doi: 10.1002/14651858.CD011006.pub4. PMID: 36999619Free PMC Article
Outcomes and prognosis of adjustment disorder in adults: A systematic review.
Morgan MA, Kelber MS, Bellanti DM, Beech EH, Boyd C, Galloway L, Ojha S, Garvey Wilson AL, Otto J, Belsher BE
J Psychiatr Res 2022 Dec;156:498-510. Epub 2022 Nov 1 doi: 10.1016/j.jpsychires.2022.10.052. PMID: 36347110
Systematic review and meta-analysis of predictors of adjustment disorders in adults.
Kelber MS, Morgan MA, Beech EH, Smolenski DJ, Bellanti D, Galloway L, Ojha S, Otto JL, Wilson ALG, Bush N, Belsher BE
J Affect Disord 2022 May 1;304:43-58. Epub 2022 Feb 15 doi: 10.1016/j.jad.2022.02.038. PMID: 35176345
Therapeutic Interventions for Adjustment Disorder: A Systematic Review.
Constantin D, Dinu EA, Rogozea L, Burtea V, Leasu FG
Am J Ther 2020 Jul/Aug;27(4):e375-e386. doi: 10.1097/MJT.0000000000001170. PMID: 32520732

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