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Mental disorder

MedGen UID:
14047
Concept ID:
C0004936
Mental or Behavioral Dysfunction
Synonym: Mental Disorders
SNOMED CT: Mental disorder (74732009); Mental illness (74732009); Mental disease (74732009); Psychiatric illness (74732009); Psychiatric disorder (74732009); Mental health disorder (74732009)
 
Monarch Initiative: MONDO:0005084

Definition

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Mental disorder

Professional guidelines

PubMed

Galbally M, Himmerich H, Senaratne S, Fitzgerald P, Frost J, Woods N, Dickinson JE
Lancet Psychiatry 2022 May;9(5):402-412. Epub 2022 Mar 24 doi: 10.1016/S2215-0366(22)00031-1. PMID: 35339207
Gontard AV, Kuwertz-Bröking E
Dtsch Arztebl Int 2019 Apr 19;116(16):279-285. doi: 10.3238/arztebl.2019.0279. PMID: 31159915Free PMC Article
Girdler SJ, Confino JE, Woesner ME
Psychopharmacol Bull 2019 Feb 15;49(1):56-69. PMID: 30858639Free PMC Article

Recent clinical studies

Etiology

Herweijer E, Wang J, Hu K, Valdimarsdóttir UA, Adami HO, Sparén P, Sundström K, Fang F
JAMA Netw Open 2023 Sep 5;6(9):e2336213. doi: 10.1001/jamanetworkopen.2023.36213. PMID: 37773493Free PMC Article
van Draanen J, Tsang C, Mitra S, Phuong V, Murakami A, Karamouzian M, Richardson L
Soc Psychiatry Psychiatr Epidemiol 2022 Apr;57(4):647-671. Epub 2021 Nov 18 doi: 10.1007/s00127-021-02199-2. PMID: 34796369Free PMC Article
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268
Wakefield JC
Annu Rev Clin Psychol 2016;12:105-32. Epub 2016 Jan 11 doi: 10.1146/annurev-clinpsy-032814-112800. PMID: 26772207

Diagnosis

Stein DJ, Palk AC, Kendler KS
Psychol Med 2021 Apr;51(6):894-901. Epub 2021 Apr 12 doi: 10.1017/S0033291721001185. PMID: 33843505Free PMC Article
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268
Wakefield JC
Annu Rev Clin Psychol 2016;12:105-32. Epub 2016 Jan 11 doi: 10.1146/annurev-clinpsy-032814-112800. PMID: 26772207
Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, Silove D
Int J Epidemiol 2014 Apr;43(2):476-93. Epub 2014 Mar 19 doi: 10.1093/ije/dyu038. PMID: 24648481Free PMC Article

Therapy

Hashimoto Y, Kotake K, Watanabe N, Fujiwara T, Sakamoto S
Cochrane Database Syst Rev 2021 Sep 15;9(9):CD013575. doi: 10.1002/14651858.CD013575.pub2. PMID: 34523118Free PMC Article
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
Jacka FN, O'Neil A, Opie R, Itsiopoulos C, Cotton S, Mohebbi M, Castle D, Dash S, Mihalopoulos C, Chatterton ML, Brazionis L, Dean OM, Hodge AM, Berk M
BMC Med 2017 Jan 30;15(1):23. doi: 10.1186/s12916-017-0791-y. PMID: 28137247Free PMC Article
Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, Silove D
Int J Epidemiol 2014 Apr;43(2):476-93. Epub 2014 Mar 19 doi: 10.1093/ije/dyu038. PMID: 24648481Free PMC Article
Deacon BJ
Clin Psychol Rev 2013 Nov;33(7):846-61. Epub 2013 Apr 8 doi: 10.1016/j.cpr.2012.09.007. PMID: 23664634

Prognosis

Dalsgaard S, Thorsteinsson E, Trabjerg BB, Schullehner J, Plana-Ripoll O, Brikell I, Wimberley T, Thygesen M, Madsen KB, Timmerman A, Schendel D, McGrath JJ, Mortensen PB, Pedersen CB
JAMA Psychiatry 2020 Feb 1;77(2):155-164. doi: 10.1001/jamapsychiatry.2019.3523. PMID: 31746968Free PMC Article
Ebert DD, Buntrock C, Mortier P, Auerbach R, Weisel KK, Kessler RC, Cuijpers P, Green JG, Kiekens G, Nock MK, Demyttenaere K, Bruffaerts R
Depress Anxiety 2019 Apr;36(4):294-304. Epub 2018 Dec 6 doi: 10.1002/da.22867. PMID: 30521136Free PMC Article
Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ, Mortensen PB, Eaton WW
JAMA Psychiatry 2014 May;71(5):573-81. doi: 10.1001/jamapsychiatry.2014.16. PMID: 24806211
Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, Rahman A
Lancet 2007 Sep 8;370(9590):859-77. doi: 10.1016/S0140-6736(07)61238-0. PMID: 17804063
Angermeyer MC
Acta Psychiatr Scand Suppl 2000;(407):63-7. doi: 10.1034/j.1600-0447.2000.00012.x. PMID: 11261644

Clinical prediction guides

Buchanan A, Moore KE, Pittman B, McKee SA
Eur Psychiatry 2021 Dec 3;64(1):e75. doi: 10.1192/j.eurpsy.2021.2250. PMID: 34859762Free PMC Article
Kakaje A, Al Zohbi R, Hosam Aldeen O, Makki L, Alyousbashi A, Alhaffar MBA
BMC Psychiatry 2021 Jan 2;21(1):2. doi: 10.1186/s12888-020-03002-3. PMID: 33388026Free PMC Article
Eaton NR
Personal Ment Health 2020 Feb;14(1):76-87. Epub 2019 Jun 20 doi: 10.1002/pmh.1449. PMID: 31219231
Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H
Nutrients 2019 Oct 3;11(10) doi: 10.3390/nu11102362. PMID: 31623400Free PMC Article
Dalhuisen L, Koenraadt F, Liem M
Crim Behav Ment Health 2017 Feb;27(1):59-75. Epub 2015 Nov 25 doi: 10.1002/cbm.1984. PMID: 26602887

Recent systematic reviews

Lane MM, Gamage E, Travica N, Dissanayaka T, Ashtree DN, Gauci S, Lotfaliany M, O'Neil A, Jacka FN, Marx W
Nutrients 2022 Jun 21;14(13) doi: 10.3390/nu14132568. PMID: 35807749Free PMC Article
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article
COVID-19 Mental Disorders Collaborators
Lancet 2021 Nov 6;398(10312):1700-1712. Epub 2021 Oct 8 doi: 10.1016/S0140-6736(21)02143-7. PMID: 34634250Free PMC Article
Jones EAK, Mitra AK, Bhuiyan AR
Int J Environ Res Public Health 2021 Mar 3;18(5) doi: 10.3390/ijerph18052470. PMID: 33802278Free PMC Article
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268

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