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Mental disorder

MedGen UID:
14047
•Concept ID:
C0004936
•
Mental or Behavioral Dysfunction
Synonym: Mental Disorders
SNOMED CT: Mental disorder (74732009); Mental illness (74732009); Mental disease (74732009); Psychiatric illness (74732009); Psychiatric disorder (74732009); Mental health disorder (74732009)
 
Monarch Initiative: MONDO:0005084

Definition

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Mental disorder

Professional guidelines

PubMed

The Diagnosis and Treatment of Enuresis and Functional Daytime Urinary Incontinence.
Gontard AV, Kuwertz-Bröking E
Dtsch Arztebl Int 2019 Apr 19;116(16):279-285. doi: 10.3238/arztebl.2019.0279. PMID: 31159915Free PMC Article
Exercise as a Treatment for Schizophrenia: A Review.
Girdler SJ, Confino JE, Woesner ME
Psychopharmacol Bull 2019 Feb 15;49(1):56-69. PMID: 30858639Free PMC Article
Prevalence and Treatment of Depression, Anxiety, and Conduct Problems in US Children.
Ghandour RM, Sherman LJ, Vladutiu CJ, Ali MM, Lynch SE, Bitsko RH, Blumberg SJ
J Pediatr 2019 Mar;206:256-267.e3. Epub 2018 Oct 12 doi: 10.1016/j.jpeds.2018.09.021. PMID: 30322701Free PMC Article

Recent clinical studies

Etiology

A revised and extended systematic review and meta-analysis of the relationship between childhood adversity and adult psychiatric disorder.
McKay MT, Kilmartin L, Meagher A, Cannon M, Healy C, Clarke MC
J Psychiatr Res 2022 Dec;156:268-283. Epub 2022 Oct 10 doi: 10.1016/j.jpsychires.2022.10.015. PMID: 36274532
Mental disorder in pregnancy and the early postpartum.
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
Childhood trauma and adult mental disorder: A systematic review and meta-analysis of longitudinal cohort studies.
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268
Enduring mental health: Prevalence and prediction.
Schaefer JD, Caspi A, Belsky DW, Harrington H, Houts R, Horwood LJ, Hussong A, Ramrakha S, Poulton R, Moffitt TE
J Abnorm Psychol 2017 Feb;126(2):212-224. Epub 2016 Dec 1 doi: 10.1037/abn0000232. PMID: 27929304Free PMC Article
Diagnostic Issues and Controversies in DSM-5: Return of the False Positives Problem.
Wakefield JC
Annu Rev Clin Psychol 2016;12:105-32. Epub 2016 Jan 11 doi: 10.1146/annurev-clinpsy-032814-112800. PMID: 26772207

Diagnosis

Mental disorder in pregnancy and the early postpartum.
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
Childhood trauma and adult mental disorder: A systematic review and meta-analysis of longitudinal cohort studies.
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268
Mental disorder and social deviance.
Aftab A, Rashed MA
Int Rev Psychiatry 2021 Aug;33(5):478-485. Epub 2020 Oct 5 doi: 10.1080/09540261.2020.1815666. PMID: 33016793
Steroid-induced mental disorders in cancer patients: a systematic review.
Ismail MF, Lavelle C, Cassidy EM
Future Oncol 2017 Dec;13(29):2719-2731. Epub 2017 Nov 30 doi: 10.2217/fon-2017-0306. PMID: 29186986
The global prevalence of common mental disorders: a systematic review and meta-analysis 1980-2013.
Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, Silove D
Int J Epidemiol 2014 Apr;43(2):476-93. Epub 2014 Mar 19 doi: 10.1093/ije/dyu038. PMID: 24648481Free PMC Article

Therapy

Lamotrigine in the maintenance treatment of bipolar disorder.
Hashimoto Y, Kotake K, Watanabe N, Fujiwara T, Sakamoto S
Cochrane Database Syst Rev 2021 Sep 15;9(9):CD013575. doi: 10.1002/14651858.CD013575.pub2. PMID: 34523118Free PMC Article
Mental disorder in pregnancy and the early postpartum.
Cantwell R
Anaesthesia 2021 Apr;76 Suppl 4:76-83. doi: 10.1111/anae.15424. PMID: 33682099
Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H
Nutrients 2019 Oct 3;11(10) doi: 10.3390/nu11102362. PMID: 31623400Free PMC Article
Steroid-induced mental disorders in cancer patients: a systematic review.
Ismail MF, Lavelle C, Cassidy EM
Future Oncol 2017 Dec;13(29):2719-2731. Epub 2017 Nov 30 doi: 10.2217/fon-2017-0306. PMID: 29186986
The global prevalence of common mental disorders: a systematic review and meta-analysis 1980-2013.
Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, Silove D
Int J Epidemiol 2014 Apr;43(2):476-93. Epub 2014 Mar 19 doi: 10.1093/ije/dyu038. PMID: 24648481Free PMC Article

Prognosis

Incidence Rates and Cumulative Incidences of the Full Spectrum of Diagnosed Mental Disorders in Childhood and Adolescence.
Dalsgaard S, Thorsteinsson E, Trabjerg BB, Schullehner J, Plana-Ripoll O, Brikell I, Wimberley T, Thygesen M, Madsen KB, Timmerman A, Schendel D, McGrath JJ, Mortensen PB, Pedersen CB
JAMA Psychiatry 2020 Feb 1;77(2):155-164. doi: 10.1001/jamapsychiatry.2019.3523. PMID: 31746968Free PMC Article
Prediction of major depressive disorder onset in college students.
Ebert DD, Buntrock C, Mortier P, Auerbach R, Weisel KK, Kessler RC, Cuijpers P, Green JG, Kiekens G, Nock MK, Demyttenaere K, Bruffaerts R
Depress Anxiety 2019 Apr;36(4):294-304. Epub 2018 Dec 6 doi: 10.1002/da.22867. PMID: 30521136Free PMC Article
Intimate partner violence and incidence of common mental disorder.
Mendonça MFS, Ludermir AB
Rev Saude Publica 2017 Apr 10;51:32. doi: 10.1590/S1518-8787.2017051006912. PMID: 28423141Free PMC Article
Childhood sexual abuse and supportive factors.
Baytunca MB, Ata E, Ozbaran B, Kaya A, Kose S, Aktas EO, Aydın R, Guney S, Yuncu Z, Erermis S, Bildik T, Aydin C
Pediatr Int 2017 Jan;59(1):10-15. Epub 2016 Sep 5 doi: 10.1111/ped.13065. PMID: 27288641
No health without mental health.
Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, Rahman A
Lancet 2007 Sep 8;370(9590):859-77. doi: 10.1016/S0140-6736(07)61238-0. PMID: 17804063

Clinical prediction guides

Mental illness-related stigma among probation officers.
Givens A, Jacobs LA, Canada KE, Edwards D Jr
Crim Behav Ment Health 2022 Apr;32(2):138-147. Epub 2022 Apr 26 doi: 10.1002/cbm.2235. PMID: 35474523
Mental disorder and PTSD in Syria during wartime: a nationwide crisis.
Kakaje A, Al Zohbi R, Hosam Aldeen O, Makki L, Alyousbashi A, Alhaffar MBA
BMC Psychiatry 2021 Jan 2;21(1):2. doi: 10.1186/s12888-020-03002-3. PMID: 33388026Free PMC Article
Assessment of the Efficacy of Withania somnifera Root Extract in Patients with Generalized Anxiety Disorder: A Randomized Double-blind Placebo- Controlled Trial.
Fuladi S, Emami SA, Mohammadpour AH, Karimani A, Manteghi AA, Sahebkar A
Curr Rev Clin Exp Pharmacol 2021;16(2):191-196. doi: 10.2174/1574884715666200413120413. PMID: 32282308
Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H
Nutrients 2019 Oct 3;11(10) doi: 10.3390/nu11102362. PMID: 31623400Free PMC Article
Subtypes of firesetters.
Dalhuisen L, Koenraadt F, Liem M
Crim Behav Ment Health 2017 Feb;27(1):59-75. Epub 2015 Nov 25 doi: 10.1002/cbm.1984. PMID: 26602887

Recent systematic reviews

Ultra-Processed Food Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies.
Lane MM, Gamage E, Travica N, Dissanayaka T, Ashtree DN, Gauci S, Lotfaliany M, O'Neil A, Jacka FN, Marx W
Nutrients 2022 Jun 21;14(13) doi: 10.3390/nu14132568. PMID: 35807749Free PMC Article
Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article
Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic.
COVID-19 Mental Disorders Collaborators
Lancet 2021 Nov 6;398(10312):1700-1712. Epub 2021 Oct 8 doi: 10.1016/S0140-6736(21)02143-7. PMID: 34634250Free PMC Article
Impact of COVID-19 on Mental Health in Adolescents: A Systematic Review.
Jones EAK, Mitra AK, Bhuiyan AR
Int J Environ Res Public Health 2021 Mar 3;18(5) doi: 10.3390/ijerph18052470. PMID: 33802278Free PMC Article
Childhood trauma and adult mental disorder: A systematic review and meta-analysis of longitudinal cohort studies.
McKay MT, Cannon M, Chambers D, Conroy RM, Coughlan H, Dodd P, Healy C, O'Donnell L, Clarke MC
Acta Psychiatr Scand 2021 Mar;143(3):189-205. Epub 2021 Jan 18 doi: 10.1111/acps.13268. PMID: 33315268

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