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Abnormality of hepatobiliary system physiology

MedGen UID:
1368531
•Concept ID:
C4476621
•
Finding
HPO: HP:0025155

Definition

A functional anomaly of the hepatobiliary system [from HPO]

Professional guidelines

PubMed

Consensus clinical management guidelines for Alström syndrome.
Tahani N, Maffei P, Dollfus H, Paisey R, Valverde D, Milan G, Han JC, Favaretto F, Madathil SC, Dawson C, Armstrong MJ, Warfield AT, Düzenli S, Francomano CA, Gunay-Aygun M, Dassie F, Marion V, Valenti M, Leeson-Beevers K, Chivers A, Steeds R, Barrett T, Geberhiwot T
Orphanet J Rare Dis 2020 Sep 21;15(1):253. doi: 10.1186/s13023-020-01468-8. PMID: 32958032Free PMC Article
Management options for cholestatic liver disease in children.
Catzola A, Vajro P
Expert Rev Gastroenterol Hepatol 2017 Nov;11(11):1019-1030. Epub 2017 Jul 28 doi: 10.1080/17474124.2017.1359538. PMID: 28745070
The pathophysiology, evaluation and management of motility disorders of the biliary tract.
Summers RW, Johlin FC
Gastroenterol Clin North Am 1989 Jun;18(2):425-35. PMID: 2668177

Recent clinical studies

Etiology

The hepatobiliary complications of malnutrition and nutritional support in adults.
McNeice A, Scott R, Rafferty GP, Cash WJ, Turner GB
Ir J Med Sci 2019 Feb;188(1):109-117. Epub 2018 May 31 doi: 10.1007/s11845-018-1836-8. PMID: 29850987
Management options for cholestatic liver disease in children.
Catzola A, Vajro P
Expert Rev Gastroenterol Hepatol 2017 Nov;11(11):1019-1030. Epub 2017 Jul 28 doi: 10.1080/17474124.2017.1359538. PMID: 28745070
Advances in primary sclerosing cholangitis.
Horsley-Silva JL, Carey EJ, Lindor KD
Lancet Gastroenterol Hepatol 2016 Sep;1(1):68-77. Epub 2016 Aug 10 doi: 10.1016/S2468-1253(16)30010-3. PMID: 28404115
Coagulation in hepatobiliary disease.
Kavanagh C, Shaw S, Webster CR
J Vet Emerg Crit Care (San Antonio) 2011 Dec;21(6):589-604. doi: 10.1111/j.1476-4431.2011.00691.x. PMID: 22316251
Cholangiocyte biology.
Tietz PS, LaRusso NF
Curr Opin Gastroenterol 2005 May;21(3):337-43. doi: 10.1097/01.mog.0000158111.21345.c2. PMID: 15818155

Diagnosis

Integrative analysis of long extracellular RNAs reveals a detection panel of noncoding RNAs for liver cancer.
Zhu Y, Wang S, Xi X, Zhang M, Liu X, Tang W, Cai P, Xing S, Bao P, Jin Y, Zhao W, Chen Y, Zhao H, Jia X, Lu S, Lu Y, Chen L, Yin J, Lu ZJ
Theranostics 2021;11(1):181-193. Epub 2021 Jan 1 doi: 10.7150/thno.48206. PMID: 33391469Free PMC Article
Management options for cholestatic liver disease in children.
Catzola A, Vajro P
Expert Rev Gastroenterol Hepatol 2017 Nov;11(11):1019-1030. Epub 2017 Jul 28 doi: 10.1080/17474124.2017.1359538. PMID: 28745070
Advances in primary sclerosing cholangitis.
Horsley-Silva JL, Carey EJ, Lindor KD
Lancet Gastroenterol Hepatol 2016 Sep;1(1):68-77. Epub 2016 Aug 10 doi: 10.1016/S2468-1253(16)30010-3. PMID: 28404115
Hepatic encephalopathy in alcoholic cirrhosis.
Butterworth RF
Handb Clin Neurol 2014;125:589-602. doi: 10.1016/B978-0-444-62619-6.00034-3. PMID: 25307598
Overview of neonatal lupus.
Johnson B
J Pediatr Health Care 2014 Jul-Aug;28(4):331-41. Epub 2013 Oct 5 doi: 10.1016/j.pedhc.2013.07.015. PMID: 24100008

Therapy

The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
The hepatobiliary complications of malnutrition and nutritional support in adults.
McNeice A, Scott R, Rafferty GP, Cash WJ, Turner GB
Ir J Med Sci 2019 Feb;188(1):109-117. Epub 2018 May 31 doi: 10.1007/s11845-018-1836-8. PMID: 29850987
Management options for cholestatic liver disease in children.
Catzola A, Vajro P
Expert Rev Gastroenterol Hepatol 2017 Nov;11(11):1019-1030. Epub 2017 Jul 28 doi: 10.1080/17474124.2017.1359538. PMID: 28745070
Advances in primary sclerosing cholangitis.
Horsley-Silva JL, Carey EJ, Lindor KD
Lancet Gastroenterol Hepatol 2016 Sep;1(1):68-77. Epub 2016 Aug 10 doi: 10.1016/S2468-1253(16)30010-3. PMID: 28404115
Potential therapeutic targets for the primary gallbladder carcinoma: estrogen receptors.
Zhang LQ, Zhang XD, Xu J, Wan Y, Qu K, Zhang JY, Wang ZX, Wei JC, Meng FD, Tai MH, Zhou L, Liu C
Asian Pac J Cancer Prev 2013;14(4):2185-90. doi: 10.7314/apjcp.2013.14.4.2185. PMID: 23725110

Prognosis

The Spectrum of Disease Severity in Cirrhosis and Its Implications for Hemostasis.
Stotts MJ, Lisman T, Intagliata NM
Semin Thromb Hemost 2020 Sep;46(6):716-723. Epub 2020 Aug 20 doi: 10.1055/s-0040-1715449. PMID: 32820482
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Advances in primary sclerosing cholangitis.
Horsley-Silva JL, Carey EJ, Lindor KD
Lancet Gastroenterol Hepatol 2016 Sep;1(1):68-77. Epub 2016 Aug 10 doi: 10.1016/S2468-1253(16)30010-3. PMID: 28404115
Coagulation in hepatobiliary disease.
Kavanagh C, Shaw S, Webster CR
J Vet Emerg Crit Care (San Antonio) 2011 Dec;21(6):589-604. doi: 10.1111/j.1476-4431.2011.00691.x. PMID: 22316251
Pathogenesis of gallstones.
Carey MC
Am J Surg 1993 Apr;165(4):410-9. doi: 10.1016/s0002-9610(05)80932-8. PMID: 8480873

Clinical prediction guides

Clinical profiles and diagnostic challenges in 1158 children with rare hepatobiliary disorders.
Dong Y, Wang J, Zhu S, Zheng H, Wang C, Zhao P
Pediatr Res 2021 Jan;89(1):238-245. Epub 2020 Apr 12 doi: 10.1038/s41390-020-0888-4. PMID: 32289814
The Spectrum of Disease Severity in Cirrhosis and Its Implications for Hemostasis.
Stotts MJ, Lisman T, Intagliata NM
Semin Thromb Hemost 2020 Sep;46(6):716-723. Epub 2020 Aug 20 doi: 10.1055/s-0040-1715449. PMID: 32820482
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis.
Luo Y, Wang Y, Shu Y, Lu Q, Xiao R
Int J Biochem Cell Biol 2015 Oct;67:92-100. Epub 2015 Jun 1 doi: 10.1016/j.biocel.2015.05.023. PMID: 26043891
Advances in prognostic factors in acute pancreatitis: a mini-review.
Pavlidis TE, Pavlidis ET, Sakantamis AK
Hepatobiliary Pancreat Dis Int 2010 Oct;9(5):482-6. PMID: 20943456

Recent systematic reviews

Consensus clinical management guidelines for Alström syndrome.
Tahani N, Maffei P, Dollfus H, Paisey R, Valverde D, Milan G, Han JC, Favaretto F, Madathil SC, Dawson C, Armstrong MJ, Warfield AT, Düzenli S, Francomano CA, Gunay-Aygun M, Dassie F, Marion V, Valenti M, Leeson-Beevers K, Chivers A, Steeds R, Barrett T, Geberhiwot T
Orphanet J Rare Dis 2020 Sep 21;15(1):253. doi: 10.1186/s13023-020-01468-8. PMID: 32958032Free PMC Article
Neurodevelopmental Outcomes in Children With Liver Diseases: a Systematic Review.
Rodijk LH, den Heijer AE, Hulscher JBF, Verkade HJ, de Kleine RHJ, Bruggink JLM
J Pediatr Gastroenterol Nutr 2018 Aug;67(2):157-168. doi: 10.1097/MPG.0000000000001981. PMID: 29601439

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