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Inflammatory cap polyp

MedGen UID:
1370135
•Concept ID:
C4476647
•
Disease or Syndrome
HPO: HP:0025198

Definition

A non-malignant sessile or pedunculated polyp in the colon and rectum that displays a cap of inflammatory granulation tissue with fibrinopurulent exudate that covers the polyp. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInflammatory cap polyp

Professional guidelines

PubMed

Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium.
Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
Endoscopic mucosal resection for cap poliposis treatment.
Monsalve Alonso S, Miranda García P, Santander Vaquero C
Rev Esp Enferm Dig 2020 Feb;112(2):155. doi: 10.17235/reed.2020.6537/2019. PMID: 31960689

Recent clinical studies

Etiology

Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium.
Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
Dietary Inflammatory Index and Odds of Colorectal Cancer and Colorectal Adenomatous Polyps in A Case-Control Study from Iran.
Rafiee P, Shivappa N, Hébert JR, Nasab SJ, Bahrami A, Hekmatdoost A, Rashidkhani B, Sadeghi A, Houshyari M, Hejazi E
Nutrients 2019 May 28;11(6) doi: 10.3390/nu11061213. PMID: 31142015Free PMC Article
Advanced imaging in colonoscopy and its impact on quality.
Sharma P, Gupta N, Kuipers EJ, Repici A, Wallace M
Gastrointest Endosc 2014 Jan;79(1):28-36. Epub 2013 Oct 9 doi: 10.1016/j.gie.2013.08.020. PMID: 24119713
Cap polyposis: a rare cause of rectal bleeding in children.
Li JH, Leong MY, Phua KB, Low Y, Kader A, Logarajah V, Ong LY, Chua JH, Ong C
World J Gastroenterol 2013 Jul 14;19(26):4185-91. doi: 10.3748/wjg.v19.i26.4185. PMID: 23864782Free PMC Article
Inflammatory myoglandular polyp of the cecum: case report and review of literature.
Meniconi RL, Caronna R, Benedetti M, Fanello G, Ciardi A, Schiratti M, Papini F, Farelli F, Dinatale G, Chirletti P
BMC Gastroenterol 2010 Jan 26;10:10. doi: 10.1186/1471-230X-10-10. PMID: 20102635Free PMC Article

Diagnosis

Cap Polyposis: A Case Report.
Khadka T, Giri GK, Sherpa P, Shrestha N, Poudyal S
JNMA J Nepal Med Assoc 2023 Jun 1;61(262):555-558. doi: 10.31729/jnma.8177. PMID: 37464856Free PMC Article
Inflammatory cap polyp of the sigmoid colon: a case report.
Pandit N, Yadav TN, Dahal M, Awale L, Adhikary S
J Med Case Rep 2021 May 29;15(1):306. doi: 10.1186/s13256-021-02857-8. PMID: 34049569Free PMC Article
Cap polyposis in children: case report and literature review.
Brunner M, Agaimy A, Atreya R, Grützmann R, Matzel KE
Int J Colorectal Dis 2019 Feb;34(2):363-368. Epub 2018 Nov 13 doi: 10.1007/s00384-018-3192-6. PMID: 30426196
Advanced imaging in colonoscopy and its impact on quality.
Sharma P, Gupta N, Kuipers EJ, Repici A, Wallace M
Gastrointest Endosc 2014 Jan;79(1):28-36. Epub 2013 Oct 9 doi: 10.1016/j.gie.2013.08.020. PMID: 24119713
Transparent cap colonoscopy versus standard colonoscopy to improve caecal intubation.
Morgan J, Thomas K, Lee-Robichaud H, Nelson RL, Braungart S
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD008211. doi: 10.1002/14651858.CD008211.pub3. PMID: 23235654Free PMC Article

Therapy

Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium.
Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
Dietary Inflammatory Index and Odds of Colorectal Cancer and Colorectal Adenomatous Polyps in A Case-Control Study from Iran.
Rafiee P, Shivappa N, Hébert JR, Nasab SJ, Bahrami A, Hekmatdoost A, Rashidkhani B, Sadeghi A, Houshyari M, Hejazi E
Nutrients 2019 May 28;11(6) doi: 10.3390/nu11061213. PMID: 31142015Free PMC Article
Dysbiosis-Associated Polyposis of the Colon-Cap Polyposis.
Okamoto K, Watanabe T, Komeda Y, Okamoto A, Minaga K, Kamata K, Yamao K, Takenaka M, Hagiwara S, Sakurai T, Tanaka T, Sakamoto H, Fujimoto K, Nishida N, Kudo M
Front Immunol 2018;9:918. Epub 2018 May 7 doi: 10.3389/fimmu.2018.00918. PMID: 29867933Free PMC Article
Transparent cap colonoscopy versus standard colonoscopy to improve caecal intubation.
Morgan J, Thomas K, Lee-Robichaud H, Nelson RL, Braungart S
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD008211. doi: 10.1002/14651858.CD008211.pub3. PMID: 23235654Free PMC Article
Transparent Cap Colonoscopy versus Standard Colonoscopy for Investigation of Gastrointestinal Tract Conditions.
Morgan J, Thomas K, Lee-Robichaud H, Nelson RL
Cochrane Database Syst Rev 2011 Feb 16;(2):CD008211. doi: 10.1002/14651858.CD008211.pub2. PMID: 21328306

Prognosis

Endoscopic mucosal resection for cap poliposis treatment.
Monsalve Alonso S, Miranda García P, Santander Vaquero C
Rev Esp Enferm Dig 2020 Feb;112(2):155. doi: 10.17235/reed.2020.6537/2019. PMID: 31960689
The time course of nasal cytokine secretion in patients with aspirin-exacerbated respiratory disease (AERD) undergoing aspirin desensitization: preliminary data.
San Nicoló M, Högerle C, Gellrich D, Eder K, Pfrogner E, Gröger M
Eur Arch Otorhinolaryngol 2020 Feb;277(2):445-452. Epub 2019 Oct 26 doi: 10.1007/s00405-019-05704-1. PMID: 31655881
Virtual Chromoendoscopy With FICE for the Classification of Polypoid and Nonpolypoid Raised Lesions in Ulcerative Colitis.
Cassinotti A, Buffoli F, Fociani P, Staiano T, Villanacci V, Nebuloni M, Duca P, Fichera M, Grassia R, Manes G, Salemme M, Molteni P, Sampietro G, Foschi D, de Franchis R, Ardizzone S
J Clin Gastroenterol 2019 Apr;53(4):269-276. doi: 10.1097/MCG.0000000000000974. PMID: 29394176
Cap polyposis: a rare cause of rectal bleeding in children.
Li JH, Leong MY, Phua KB, Low Y, Kader A, Logarajah V, Ong LY, Chua JH, Ong C
World J Gastroenterol 2013 Jul 14;19(26):4185-91. doi: 10.3748/wjg.v19.i26.4185. PMID: 23864782Free PMC Article
Cap polyposis: further experience and review.
Ng KH, Mathur P, Kumarasinghe MP, Eu KW, Seow-Choen F
Dis Colon Rectum 2004 Jul;47(7):1208-15. Epub 2004 Jun 3 doi: 10.1007/s10350-004-0561-8. PMID: 15164251

Clinical prediction guides

Dietary Inflammatory Index and Odds of Colorectal Cancer and Colorectal Adenomatous Polyps in A Case-Control Study from Iran.
Rafiee P, Shivappa N, Hébert JR, Nasab SJ, Bahrami A, Hekmatdoost A, Rashidkhani B, Sadeghi A, Houshyari M, Hejazi E
Nutrients 2019 May 28;11(6) doi: 10.3390/nu11061213. PMID: 31142015Free PMC Article
Virtual Chromoendoscopy With FICE for the Classification of Polypoid and Nonpolypoid Raised Lesions in Ulcerative Colitis.
Cassinotti A, Buffoli F, Fociani P, Staiano T, Villanacci V, Nebuloni M, Duca P, Fichera M, Grassia R, Manes G, Salemme M, Molteni P, Sampietro G, Foschi D, de Franchis R, Ardizzone S
J Clin Gastroenterol 2019 Apr;53(4):269-276. doi: 10.1097/MCG.0000000000000974. PMID: 29394176
Dysbiosis-Associated Polyposis of the Colon-Cap Polyposis.
Okamoto K, Watanabe T, Komeda Y, Okamoto A, Minaga K, Kamata K, Yamao K, Takenaka M, Hagiwara S, Sakurai T, Tanaka T, Sakamoto H, Fujimoto K, Nishida N, Kudo M
Front Immunol 2018;9:918. Epub 2018 May 7 doi: 10.3389/fimmu.2018.00918. PMID: 29867933Free PMC Article
Nasal polyposis: from cytokines to growth.
Bachert C, Gevaert P, Holtappels G, Cuvelier C, van Cauwenberge P
Am J Rhinol 2000 Sep-Oct;14(5):279-90. doi: 10.2500/105065800781329573. PMID: 11068652
Inflammatory myoglandular polyps of the colon and rectum. A clinicopathological study of 32 pedunculated polyps, distinct from other types of polyps.
Nakamura S, Kino I, Akagi T
Am J Surg Pathol 1992 Aug;16(8):772-9. doi: 10.1097/00000478-199208000-00005. PMID: 1309176

Recent systematic reviews

Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum.
Brown SR, Baraza W, Din S, Riley S
Cochrane Database Syst Rev 2016 Apr 7;4(4):CD006439. doi: 10.1002/14651858.CD006439.pub4. PMID: 27056645Free PMC Article
Transparent cap colonoscopy versus standard colonoscopy to improve caecal intubation.
Morgan J, Thomas K, Lee-Robichaud H, Nelson RL, Braungart S
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD008211. doi: 10.1002/14651858.CD008211.pub3. PMID: 23235654Free PMC Article
Transparent Cap Colonoscopy versus Standard Colonoscopy for Investigation of Gastrointestinal Tract Conditions.
Morgan J, Thomas K, Lee-Robichaud H, Nelson RL
Cochrane Database Syst Rev 2011 Feb 16;(2):CD008211. doi: 10.1002/14651858.CD008211.pub2. PMID: 21328306

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