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Dysgenesis of the thalamus

MedGen UID:
1370276
Concept ID:
C4476589
Anatomical Abnormality
Synonym: Thalamic dysgenesis
 
HPO: HP:0025099

Definition

Structural abnormality of the thalamus related to defective development. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Cromb D, Bonthrone AF, Maggioni A, Cawley P, Dimitrova R, Kelly CJ, Cordero-Grande L, Carney O, Egloff A, Hughes E, Hajnal JV, Simpson J, Pushparajah K, Rutherford MA, Edwards AD, O'Muircheartaigh J, Counsell SJ
J Am Heart Assoc 2023 Jul 18;12(14):e028565. Epub 2023 Jul 8 doi: 10.1161/JAHA.122.028565. PMID: 37421268Free PMC Article
Patel J, Feghali J, Yang W, Rapaport S, Gami A, Sattari SA, Tamargo RJ, Caplan JM, Huang J
J Clin Neurosci 2021 Oct;92:191-196. Epub 2021 Aug 24 doi: 10.1016/j.jocn.2021.08.010. PMID: 34509251
Brown WT
Can Med Assoc J 1973 Mar 17;108(6):742-4 passim. PMID: 4570682Free PMC Article

Recent clinical studies

Etiology

Tos SM, Mantziaris G, Shaaban A, Sheehan JP
Neurosurg Rev 2024 Apr 24;47(1):186. doi: 10.1007/s10143-024-02434-9. PMID: 38653844Free PMC Article
Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, Cadwell CR, Bhaduri A, Popova G, Bearden CE, Pollen AA, Jacquemont S, Sanders SJ, Haussler D, Wiita AP, Frost NA, Sohal VS, Nowakowski TJ
Cell Stem Cell 2024 Mar 7;31(3):421-432.e8. Epub 2024 Feb 20 doi: 10.1016/j.stem.2024.01.010. PMID: 38382530Free PMC Article
Nagy G, Kemeny AA
J Neurosurg Sci 2015 Sep;59(3):295-306. Epub 2015 May 13 PMID: 25968927
Koepp MJ, Duncan JS
Curr Opin Neurol 2004 Aug;17(4):467-74. doi: 10.1097/01.wco.0000137539.91738.2b. PMID: 15247544
Valenstein E, Bowers D, Verfaellie M, Heilman KM, Day A, Watson RT
Brain 1987 Dec;110 ( Pt 6):1631-46. doi: 10.1093/brain/110.6.1631. PMID: 3427404

Diagnosis

Pauly MG, Brüggemann N, Efthymiou S, Grözinger A, Diaw SH, Chelban V, Turchetti V, Vona B, Tadic V, Houlden H, Münchau A, Lohmann K
Int J Mol Sci 2023 Jan 18;24(3) doi: 10.3390/ijms24031874. PMID: 36768210Free PMC Article
Moretti R, Caruso P
Int J Mol Sci 2020 Sep 5;21(18) doi: 10.3390/ijms21186506. PMID: 32899565Free PMC Article
Tsai JD, Kuo HT, Chou IC
Pediatr Neonatol 2008 Aug;49(4):154-7. doi: 10.1016/S1875-9572(08)60032-7. PMID: 19054923
Beshkar M
Synapse 2008 Jul;62(7):553-6. doi: 10.1002/syn.20524. PMID: 18435419
Koepp MJ, Duncan JS
Curr Opin Neurol 2004 Aug;17(4):467-74. doi: 10.1097/01.wco.0000137539.91738.2b. PMID: 15247544

Therapy

Agarwal P, Sharma N, Nayar G, Jacobs RC, Al-Bayati A, Lunsford LD, McDowell MM, Greene S
J Neurosurg Pediatr 2024 Jan 1;33(1):22-28. Epub 2023 Nov 10 doi: 10.3171/2023.9.PEDS23198. PMID: 37948702
Ohadi MAD, Iranmehr A, Chavoshi M, Fatollahi MA, Aleyasin MS, Hadjipanayis CG
Neurosurg Rev 2023 Jun 26;46(1):148. doi: 10.1007/s10143-023-02059-4. PMID: 37358733
Moretti R, Caruso P
Int J Mol Sci 2020 Sep 5;21(18) doi: 10.3390/ijms21186506. PMID: 32899565Free PMC Article
Nagy G, Kemeny AA
Neurosurg Clin N Am 2013 Oct;24(4):575-89. Epub 2013 Aug 2 doi: 10.1016/j.nec.2013.05.004. PMID: 24093575
Brown WT
Can Med Assoc J 1973 Mar 17;108(6):742-4 passim. PMID: 4570682Free PMC Article

Prognosis

Singh R, Dumot C, Mantziaris G, Dayawansa S, Xu Z, Pikis S, Peker S, Samanci Y, Ardor GD, Nabeel AM, Reda WA, Tawadros SR, Abdel Karim K, El-Shehaby AMN, Emad Eldin RM, Sheehan D, Sheehan K, Elazzazi AH, Martínez Moreno N, Martínez Álvarez R, Liscak R, May J, Mathieu D, Tourigny JN, Tripathi M, Rajput A, Kumar N, Kaur R, Picozzi P, Franzini A, Speckter H, Hernandez W, Brito A, Warnick RE, Alzate JD, Kondziolka D, Bowden GN, Patel S, Sheehan JP
J Neurosurg 2024 Jun 1;140(6):1762-1768. Epub 2023 Dec 8 doi: 10.3171/2023.10.JNS231894. PMID: 38064704
Agarwal P, Sharma N, Nayar G, Jacobs RC, Al-Bayati A, Lunsford LD, McDowell MM, Greene S
J Neurosurg Pediatr 2024 Jan 1;33(1):22-28. Epub 2023 Nov 10 doi: 10.3171/2023.9.PEDS23198. PMID: 37948702
Ohadi MAD, Iranmehr A, Chavoshi M, Fatollahi MA, Aleyasin MS, Hadjipanayis CG
Neurosurg Rev 2023 Jun 26;46(1):148. doi: 10.1007/s10143-023-02059-4. PMID: 37358733
Nagy G, Kemeny AA
J Neurosurg Sci 2015 Sep;59(3):295-306. Epub 2015 May 13 PMID: 25968927
Valenstein E, Bowers D, Verfaellie M, Heilman KM, Day A, Watson RT
Brain 1987 Dec;110 ( Pt 6):1631-46. doi: 10.1093/brain/110.6.1631. PMID: 3427404

Clinical prediction guides

Mantziaris G, Pikis S, Dumot C, Dayawansa S, Liscak R, May J, Lee CC, Yang HC, Martínez Moreno N, Martinez Álvarez R, Lunsford LD, Niranjan A, Wei Z, Srinivasan P, Tang LW, Nabeel AM, Reda WA, Tawadros SR, Abdel Karim K, El-Shehaby AMN, Emad Eldin RM, Elazzazi AH, Peker S, Samanci Y, Padmanaban V, Jareczek FJ, McInerney J, Cockroft KM, Mathieu D, Aldakhil S, Alzate JD, Kondziolka D, Tripathi M, Palmer JD, Upadhyay R, Lin M, Zada G, Yu C, Cifarelli CP, Cifarelli DT, Shaaban A, Xu Z, Sheehan JP
J Neurosurg 2024 Jun 1;140(6):1753-1761. Epub 2023 Dec 22 doi: 10.3171/2023.10.JNS231957. PMID: 38134430
Agarwal P, Sharma N, Nayar G, Jacobs RC, Al-Bayati A, Lunsford LD, McDowell MM, Greene S
J Neurosurg Pediatr 2024 Jan 1;33(1):22-28. Epub 2023 Nov 10 doi: 10.3171/2023.9.PEDS23198. PMID: 37948702
Jiang Y, Patton MH, Zakharenko SS
Front Neural Circuits 2021;15:769969. Epub 2021 Dec 8 doi: 10.3389/fncir.2021.769969. PMID: 34955759Free PMC Article
Moretti R, Caruso P
Int J Mol Sci 2020 Sep 5;21(18) doi: 10.3390/ijms21186506. PMID: 32899565Free PMC Article
Nagy G, Kemeny AA
J Neurosurg Sci 2015 Sep;59(3):295-306. Epub 2015 May 13 PMID: 25968927

Recent systematic reviews

Tos SM, Mantziaris G, Shaaban A, Sheehan JP
Neurosurg Rev 2024 Apr 24;47(1):186. doi: 10.1007/s10143-024-02434-9. PMID: 38653844Free PMC Article
Ohadi MAD, Iranmehr A, Chavoshi M, Fatollahi MA, Aleyasin MS, Hadjipanayis CG
Neurosurg Rev 2023 Jun 26;46(1):148. doi: 10.1007/s10143-023-02059-4. PMID: 37358733
Kurzbuch AR, Cooper B, Israni A, Ellenbogen JR
Childs Nerv Syst 2023 Feb;39(2):451-462. Epub 2022 Aug 6 doi: 10.1007/s00381-022-05638-w. PMID: 35933521

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