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Unilateral alveolar cleft of maxilla

MedGen UID:
1371734
•Concept ID:
C4477070
•
Congenital Abnormality
HPO: HP:0410033

Definition

One sided alveolar cleft of the maxilla. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnilateral alveolar cleft of maxilla

Professional guidelines

PubMed

Growth of Palate in Unilateral Cleft Lip and Palate Patients Undergoing Two-stage Palatoplasty and Orthodontic Treatment.
Eriguchi M, Watanabe A, Suga K, Nakano Y, Sakamoto T, Sueishi K, Uchiyama T
Bull Tokyo Dent Coll 2018;59(3):183-191. doi: 10.2209/tdcpublication.2017-0014. PMID: 30224612
Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735
Combined orthodontic-surgical treatment of alveolar clefts.
Enemark H, Sindet-Pedersen S, Bundgaard M, Simonsen EK
Ann Plast Surg 1988 Aug;21(2):127-33. doi: 10.1097/00000637-198808000-00006. PMID: 3052234

Recent clinical studies

Etiology

The Effects of Gingivoperiosteoplasty and Cleft Palate Repair on Facial Growth.
Park JJ, Kalra A, Parsaei Y, Rochlin DH, Verzella A, Grayson BH, Cutting CB, Shetye PR, Flores RL
Plast Reconstr Surg 2024 May 1;153(5):1110-1119. Epub 2023 May 15 doi: 10.1097/PRS.0000000000010681. PMID: 37184473
Three-Dimensional Measurement of the Zygomatic-Maxillary Complex in Unilateral Cleft Lip and Palate Patients With Maxillary Retrusion.
Zheng Y, Jiang C, Ma H, Yin N, Zhai J, Tong H, Song T
J Craniofac Surg 2022 Mar-Apr 01;33(2):e179-e182. doi: 10.1097/SCS.0000000000008259. PMID: 35385238
Assessment of Bioabsorbable Hydroxyapatite for Secondary Bone Grafting in Unilateral Alveolar Clefts.
Sakamoto Y, Sakamoto T, Ishii T, Kishi K
Cleft Palate Craniofac J 2020 Jan;57(1):114-117. Epub 2019 Aug 18 doi: 10.1177/1055665619866372. PMID: 31422680
Bone-anchored maxillary protraction in unilateral cleft lip and palate: a cephalometric appraisal.
Faco R, Yatabe M, Cevidanes LHS, Timmerman H, De Clerck HJ, Garib D
Eur J Orthod 2019 Sep 21;41(5):537-543. doi: 10.1093/ejo/cjz005. PMID: 30865780Free PMC Article
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562

Diagnosis

Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate.
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
First-Trimester Sonographic Evaluation of Palatine Clefts: A Novel Diagnostic Approach.
Lakshmy SR, Deepa S, Rose N, Mookan S, Agnees J
J Ultrasound Med 2017 Jul;36(7):1397-1414. Epub 2017 Apr 18 doi: 10.7863/ultra.16.05084. PMID: 28417474
New neonatal classification of unilateral cleft lip and palate part 2: to predict permanent lateral incisor agenesis and maxillary growth.
Doucet JC, Delestan C, Montoya P, Matei L, Bigorre M, Herlin C, Baümler C, Daures JP, Captier G
Cleft Palate Craniofac J 2014 Sep;51(5):533-9. Epub 2013 Apr 26 doi: 10.1597/12-114. PMID: 23621660
Severity of alveolar cleft before palatoplasty affects vertical maxillofacial growth in 6-year-old patients with complete unilateral cleft lip and palate.
Tomita Y, Kuroda S, Katsura T, Watanabe T, Watanabe K, Fujihara S, Tanaka E
Am J Orthod Dentofacial Orthop 2012 Apr;141(4 Suppl):S102-9. doi: 10.1016/j.ajodo.2011.09.010. PMID: 22449590
Data-objective diagnosis of infant cleft lip, alveolus, and palate. Morphologic data guiding understanding and treatment concepts.
Kriens O
Cleft Palate Craniofac J 1991 Apr;28(2):157-68. doi: 10.1597/1545-1569_1991_028_0157_dodoic_2.3.co_2. PMID: 2069971

Therapy

Secondary alveolar cleft grafting using autogenous mineralized plasmatic matrix (MPM) versus cancellous bone particles derived from anterior iliac crest.
Omara M, Raafat L, Elfaramawi T
Clin Oral Investig 2023 Aug;27(8):4259-4270. Epub 2023 May 5 doi: 10.1007/s00784-023-05042-x. PMID: 37145153Free PMC Article
Dentoskeletal effects of facemask therapy in skeletal Class III cleft patients with or without bone graft.
Zhang Y, Jia H, Fu Z, Huang Y, Wang Z, Guo R, Shen J, Li W
Am J Orthod Dentofacial Orthop 2018 Apr;153(4):542-549. doi: 10.1016/j.ajodo.2017.07.024. PMID: 29602346
Evaluation of maxillary central incisors on the noncleft and cleft sides in patients with unilateral cleft lip and palate-Part 2: Relationship between root resorption, horizontal tooth movement, and quantity of grafted autogenous bone.
Maeda-Iino A, Furukawa M, Kwon S, Marutani K, Nakagawa S, Fuchigami T, Nakamura N, Miyawaki S
Angle Orthod 2017 Nov;87(6):863-870. Epub 2017 Sep 14 doi: 10.2319/031317-189.1. PMID: 28906140Free PMC Article
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381
Outcome of gingivoperiosteoplasty for the treatment of alveolar clefts in patients with unilateral cleft lip and palate.
Wang YC, Liao YF, Chen PK
Br J Oral Maxillofac Surg 2013 Oct;51(7):650-5. Epub 2012 Oct 12 doi: 10.1016/j.bjoms.2012.09.012. PMID: 23068127

Prognosis

A CBCT Based Assessment of Canine Eruption and Development Following Alveolar Bone Grafting in Patients Born With Unilateral Cleft lip and/or Palate.
Kadi H, Jacobs R, Shujaat S, Lemberger M, Benchimol D, Karsten A, Pegelow M
Cleft Palate Craniofac J 2023 Apr;60(4):386-394. Epub 2021 Dec 7 doi: 10.1177/10556656211064477. PMID: 34873962
Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate.
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Eruption path of permanent maxillary canines after secondary alveolar bone graft in patients with nonsyndromic complete unilateral cleft lip and palate.
Caceres Manfio AS, Suri S, Dupuis A, Stevens K
Am J Orthod Dentofacial Orthop 2022 May;161(5):e416-e428. Epub 2022 Mar 5 doi: 10.1016/j.ajodo.2021.06.019. PMID: 35260329
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562
Canine Eruption After Secondary Alveolar Bone Graft in Unilateral Cleft Lip and Palate Patients.
Vellone V, Cirignaco G, Cavarretta B, Cascone P
J Craniofac Surg 2017 Jul;28(5):1206-1210. doi: 10.1097/SCS.0000000000003659. PMID: 28570399

Clinical prediction guides

Closure of maxillary lateral incisor agenesis space in unilateral cleft lip and palate: a digital model assessment.
Manfio ASC, Garib D, Flores-Mir C, Lauris JRP, Teixeira R, Almeida ALPF
Dental Press J Orthod 2023;28(1):e2321331. Epub 2023 Apr 14 doi: 10.1590/2177-6709.28.1.e2321331.oar. PMID: 37075417Free PMC Article
Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate.
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Bone-anchored maxillary protraction in unilateral cleft lip and palate: a cephalometric appraisal.
Faco R, Yatabe M, Cevidanes LHS, Timmerman H, De Clerck HJ, Garib D
Eur J Orthod 2019 Sep 21;41(5):537-543. doi: 10.1093/ejo/cjz005. PMID: 30865780Free PMC Article
Evaluation of a Sample of Patients With Unilateral Cleft Lip and Palate Treated With a Two-Stage Protocol.
Brusati R, Meazzini MC, Rezzonico A, Biglioli F, Garattini G, Battista VMA, Autelitano L
J Craniofac Surg 2018 Nov;29(8):2058-2064. doi: 10.1097/SCS.0000000000004789. PMID: 30277945
The maxillary lateral incisor in the rehabilitation of cleft lip and palate.
Tereza GPG, Santos MACD, Winckler VPSV, Almeida ALPF, Dalben GDS
J Appl Oral Sci 2018;26:e20170125. Epub 2018 May 7 doi: 10.1590/1678-7757-2017-0125. PMID: 29742253Free PMC Article

Recent systematic reviews

Effects of labial adhesion on maxillary arch dimensions and nasolabial esthetics in cleft lip and palate: a systematic review.
Thierens L, Brusselaers N, De Roo N, De Pauw G
Oral Dis 2017 Oct;23(7):889-896. Epub 2017 Jan 24 doi: 10.1111/odi.12613. PMID: 27878905

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