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Unilateral alveolar cleft of maxilla

MedGen UID:
1371734
•Concept ID:
C4477070
•
Congenital Abnormality
HPO: HP:0410033

Definition

One sided alveolar cleft of the maxilla. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnilateral alveolar cleft of maxilla

Professional guidelines

PubMed

Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735
Combined orthodontic-surgical treatment of alveolar clefts.
Enemark H, Sindet-Pedersen S, Bundgaard M, Simonsen EK
Ann Plast Surg 1988 Aug;21(2):127-33. doi: 10.1097/00000637-198808000-00006. PMID: 3052234
Secondary bonegrafting in unilateral cleft lip palate patients: indications and treatment procedure.
Enemark H, Krantz-Simonsen E, Schramm JE
Int J Oral Surg 1985 Feb;14(1):2-10. doi: 10.1016/s0300-9785(85)80003-x. PMID: 3921475

Recent clinical studies

Etiology

The Effects of Gingivoperiosteoplasty and Cleft Palate Repair on Facial Growth.
Park JJ, Kalra A, Parsaei Y, Rochlin DH, Verzella A, Grayson BH, Cutting CB, Shetye PR, Flores RL
Plast Reconstr Surg 2024 May 1;153(5):1110-1119. Epub 2023 May 15 doi: 10.1097/PRS.0000000000010681. PMID: 37184473
The impact of passive alveolar molding vs. nasoalveolar molding on cleft width and other parameters of maxillary growth in unilateral cleft lip palate.
Parhofer R, Rau A, Strobel K, Gölz L, Stark R, Ritschl LM, Wolff KD, Kesting MR, Grill FD, Seidel CL
Clin Oral Investig 2023 Sep;27(9):5001-5009. Epub 2023 Jun 23 doi: 10.1007/s00784-023-05119-7. PMID: 37353667Free PMC Article
Three-Dimensional Measurement of the Zygomatic-Maxillary Complex in Unilateral Cleft Lip and Palate Patients With Maxillary Retrusion.
Zheng Y, Jiang C, Ma H, Yin N, Zhai J, Tong H, Song T
J Craniofac Surg 2022 Mar-Apr 01;33(2):e179-e182. doi: 10.1097/SCS.0000000000008259. PMID: 35385238
Assessment of Bioabsorbable Hydroxyapatite for Secondary Bone Grafting in Unilateral Alveolar Clefts.
Sakamoto Y, Sakamoto T, Ishii T, Kishi K
Cleft Palate Craniofac J 2020 Jan;57(1):114-117. Epub 2019 Aug 18 doi: 10.1177/1055665619866372. PMID: 31422680
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562

Diagnosis

Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate.
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735
First-Trimester Sonographic Evaluation of Palatine Clefts: A Novel Diagnostic Approach.
Lakshmy SR, Deepa S, Rose N, Mookan S, Agnees J
J Ultrasound Med 2017 Jul;36(7):1397-1414. Epub 2017 Apr 18 doi: 10.7863/ultra.16.05084. PMID: 28417474
New neonatal classification of unilateral cleft lip and palate part 2: to predict permanent lateral incisor agenesis and maxillary growth.
Doucet JC, Delestan C, Montoya P, Matei L, Bigorre M, Herlin C, Baümler C, Daures JP, Captier G
Cleft Palate Craniofac J 2014 Sep;51(5):533-9. Epub 2013 Apr 26 doi: 10.1597/12-114. PMID: 23621660
Combined orthodontic-surgical treatment of alveolar clefts.
Enemark H, Sindet-Pedersen S, Bundgaard M, Simonsen EK
Ann Plast Surg 1988 Aug;21(2):127-33. doi: 10.1097/00000637-198808000-00006. PMID: 3052234

Therapy

Secondary alveolar cleft grafting using autogenous mineralized plasmatic matrix (MPM) versus cancellous bone particles derived from anterior iliac crest.
Omara M, Raafat L, Elfaramawi T
Clin Oral Investig 2023 Aug;27(8):4259-4270. Epub 2023 May 5 doi: 10.1007/s00784-023-05042-x. PMID: 37145153Free PMC Article
Dentoskeletal effects of facemask therapy in skeletal Class III cleft patients with or without bone graft.
Zhang Y, Jia H, Fu Z, Huang Y, Wang Z, Guo R, Shen J, Li W
Am J Orthod Dentofacial Orthop 2018 Apr;153(4):542-549. doi: 10.1016/j.ajodo.2017.07.024. PMID: 29602346
Evaluation of maxillary central incisors on the noncleft and cleft sides in patients with unilateral cleft lip and palate-Part 2: Relationship between root resorption, horizontal tooth movement, and quantity of grafted autogenous bone.
Maeda-Iino A, Furukawa M, Kwon S, Marutani K, Nakagawa S, Fuchigami T, Nakamura N, Miyawaki S
Angle Orthod 2017 Nov;87(6):863-870. Epub 2017 Sep 14 doi: 10.2319/031317-189.1. PMID: 28906140Free PMC Article
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381
Outcome of gingivoperiosteoplasty for the treatment of alveolar clefts in patients with unilateral cleft lip and palate.
Wang YC, Liao YF, Chen PK
Br J Oral Maxillofac Surg 2013 Oct;51(7):650-5. Epub 2012 Oct 12 doi: 10.1016/j.bjoms.2012.09.012. PMID: 23068127

Prognosis

Adaptable cascaded registration for personalized maxilla completion and cleft defect volume estimation.
Zhang Y, Pei Y, Guo Y, Chen S, Zhou ZB, Xu T, Zha H
Med Phys 2024 Jun;51(6):4283-4296. Epub 2024 Mar 31 doi: 10.1002/mp.17046. PMID: 38555877
A CBCT Based Assessment of Canine Eruption and Development Following Alveolar Bone Grafting in Patients Born With Unilateral Cleft lip and/or Palate.
Kadi H, Jacobs R, Shujaat S, Lemberger M, Benchimol D, Karsten A, Pegelow M
Cleft Palate Craniofac J 2023 Apr;60(4):386-394. Epub 2021 Dec 7 doi: 10.1177/10556656211064477. PMID: 34873962
Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate.
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Eruption path of permanent maxillary canines after secondary alveolar bone graft in patients with nonsyndromic complete unilateral cleft lip and palate.
Caceres Manfio AS, Suri S, Dupuis A, Stevens K
Am J Orthod Dentofacial Orthop 2022 May;161(5):e416-e428. Epub 2022 Mar 5 doi: 10.1016/j.ajodo.2021.06.019. PMID: 35260329
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562

Clinical prediction guides

Clinical outcomes of gingivoperiosteoplasty for unilateral cleft lip and palate performed in early childhood.
Yamanishi T, Arimura Y, Kirikoshi S, Hara T, Nishio T, Seikai T, Uematsu S, Nishio J
J Plast Reconstr Aesthet Surg 2024 Oct;97:268-274. Epub 2024 Aug 3 doi: 10.1016/j.bjps.2024.07.067. PMID: 39173578
Closure of maxillary lateral incisor agenesis space in unilateral cleft lip and palate: a digital model assessment.
Manfio ASC, Garib D, Flores-Mir C, Lauris JRP, Teixeira R, Almeida ALPF
Dental Press J Orthod 2023;28(1):e2321331. Epub 2023 Apr 14 doi: 10.1590/2177-6709.28.1.e2321331.oar. PMID: 37075417Free PMC Article
Labial Vestibular Flap Closure of the Cleft Palate Is Advantageous for Maxillary Development.
Fujimoto Y, Tanaka S, Otsuki K, Yamanishi T, Isomura E, Yokota Y, Kogo M
Cleft Palate Craniofac J 2023 Feb;60(2):233-242. Epub 2022 Jan 19 doi: 10.1177/10556656211065944. PMID: 35043724
Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate.
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381

Recent systematic reviews

Effects of Secondary Alveolar Bone Grafting on Maxillary Growth in Cleft Lip or Palate Patients: A Systematic Review and Meta-Analysis.
Kannan P, Verma S, Kumar V, Kumar Verma R, Pal Singh S
Cleft Palate Craniofac J 2024 Nov;61(11):1860-1872. Epub 2023 Jul 12 doi: 10.1177/10556656231188600. PMID: 37438927
Effects of labial adhesion on maxillary arch dimensions and nasolabial esthetics in cleft lip and palate: a systematic review.
Thierens L, Brusselaers N, De Roo N, De Pauw G
Oral Dis 2017 Oct;23(7):889-896. Epub 2017 Jan 24 doi: 10.1111/odi.12613. PMID: 27878905

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