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Craniofacial cleft

MedGen UID:
1053244
Concept ID:
CN376515
Finding
HPO: HP:5201015

Definition

Congenital abnormality with cleft (gap or opening) in the craniofacial bones. Craniofacial cleft includes facial cleft, orofacial clef, and cleft of the jaw. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCraniofacial cleft

Professional guidelines

PubMed

Lee HJ, Yang IH, Baek SH
J Craniofac Surg 2021 Nov-Dec 01;32(8):e773-e778. doi: 10.1097/SCS.0000000000007769. PMID: 34727453
Lewis CW, Jacob LS, Lehmann CU; SECTION ON ORAL HEALTH
Pediatrics 2017 May;139(5) doi: 10.1542/peds.2017-0628. PMID: 28557774
Jones MC
Cleft Palate Craniofac J 2002 Mar;39(2):169-73. doi: 10.1597/1545-1569_2002_039_0169_pdocla_2.0.co_2. PMID: 11879073

Recent clinical studies

Etiology

Chan CH, Hu AC, Jain NS, Dang BN, Liu MT, Bertrand AA, Wilson LF, Lee JC
J Craniofac Surg 2021 Nov-Dec 01;32(8):2771-2773. doi: 10.1097/SCS.0000000000007938. PMID: 34727477
Lee HJ, Yang IH, Baek SH
J Craniofac Surg 2021 Nov-Dec 01;32(8):e773-e778. doi: 10.1097/SCS.0000000000007769. PMID: 34727453
Rüegg EM, Bartoli A, Rilliet B, Scolozzi P, Montandon D, Pittet-Cuénod B
J Plast Reconstr Aesthet Surg 2019 Apr;72(4):676-684. Epub 2019 Jan 9 doi: 10.1016/j.bjps.2019.01.001. PMID: 30691993
Lewis CW, Jacob LS, Lehmann CU; SECTION ON ORAL HEALTH
Pediatrics 2017 May;139(5) doi: 10.1542/peds.2017-0628. PMID: 28557774
Zhou YQ, Ji J, Mu XZ, Zhang RH, Wei M, Yu ZY
J Craniofac Surg 2006 Jan;17(1):198-201. doi: 10.1097/01.scs.0000194171.91421.b8. PMID: 16432437

Diagnosis

Nazari S, Vaezi A, Mossavarali S, Ghanavati K, Shafiee A
Eur J Pediatr 2024 Jan;183(1):73-82. Epub 2023 Nov 4 doi: 10.1007/s00431-023-05322-4. PMID: 37924347
Serigatto HR, Kokitsu-Nakata NM, Moura PP, Vendramini-Pittoli S, Virmond LA, Peixoto AP, Tonello C, Brito LA, Passos-Bueno MR, Zechi-Ceide RM
Clin Dysmorphol 2023 Jan 1;32(1):21-24. Epub 2022 Sep 12 doi: 10.1097/MCD.0000000000000434. PMID: 36503920
Gao JL, Rogers GF, Myseros JS, Habeshian KA
Pediatr Dermatol 2022 Nov;39(6):990-991. Epub 2022 Jun 8 doi: 10.1111/pde.15059. PMID: 35677994
Chan CH, Hu AC, Jain NS, Dang BN, Liu MT, Bertrand AA, Wilson LF, Lee JC
J Craniofac Surg 2021 Nov-Dec 01;32(8):2771-2773. doi: 10.1097/SCS.0000000000007938. PMID: 34727477
Zhou YQ, Ji J, Mu XZ, Zhang RH, Wei M, Yu ZY
J Craniofac Surg 2006 Jan;17(1):198-201. doi: 10.1097/01.scs.0000194171.91421.b8. PMID: 16432437

Therapy

Mapar D, Khanlar F, Sadeghi S, Abdali H, Memarzadeh M, Davari HA, Derakhshandeh F
Int J Pediatr Otorhinolaryngol 2019 May;120:6-10. Epub 2019 Jan 8 doi: 10.1016/j.ijporl.2018.12.035. PMID: 30739010
Eshghpour M, Mianbandi V, Samieirad S
J Craniofac Surg 2018 Nov;29(8):e797-e803. doi: 10.1097/SCS.0000000000004828. PMID: 30277955
Arce-Estrada GE, Gómez-Toscano V, Cedillo-Peláez C, Sesman-Bernal AL, Bosch-Canto V, Mayorga-Butrón JL, Vargas-Villavicencio JA, Correa D
BMC Infect Dis 2017 Jul 3;17(1):459. doi: 10.1186/s12879-017-2565-8. PMID: 28673238Free PMC Article
Rivas F, Hernandez A, Cantu JM
Teratology 1984 Oct;30(2):179-80. doi: 10.1002/tera.1420300204. PMID: 6495222

Prognosis

Chin MG, Roca Y, Huang KX, Moghadam S, LaGuardia JS, Bedar M, Wilson LF, Lee JC
J Plast Reconstr Aesthet Surg 2024 Jan;88:24-32. Epub 2023 Oct 23 doi: 10.1016/j.bjps.2023.10.107. PMID: 37950988Free PMC Article
Watanabe A, Yoshida S, Ishii T, Saito C, Shibahara T
Bull Tokyo Dent Coll 2019 Dec 10;60(4):291-296. Epub 2019 Nov 22 doi: 10.2209/tdcpublication.2018-0070. PMID: 31761879
Assouan C, Ambroise B, de Boutray M, Labbé D, Bénateau H, Veyssiere A
J Stomatol Oral Maxillofac Surg 2018 Jun;119(3):208-211. Epub 2017 Dec 12 doi: 10.1016/j.jormas.2017.12.005. PMID: 29246756
Nam SM, Kim YB
J Craniomaxillofac Surg 2014 Oct;42(7):1397-401. Epub 2014 Apr 13 doi: 10.1016/j.jcms.2014.03.032. PMID: 24837484
Hassani ME, Karimi H, Hassani H, Hassani A, Jalili-Manesh M
J Craniofac Surg 2014 Jan;25(1):e7-9. doi: 10.1097/SCS.0b013e3182a2ec3a. PMID: 24275777

Clinical prediction guides

Khan M, Hidayatullah, Hayat W, Khattak DA, Khan A, Hayat N, Amjad Q, Khan R
J Plast Reconstr Aesthet Surg 2024 Oct;97:41-49. Epub 2024 Jul 27 doi: 10.1016/j.bjps.2024.07.043. PMID: 39137523
Chin MG, Roca Y, Huang KX, Moghadam S, LaGuardia JS, Bedar M, Wilson LF, Lee JC
J Plast Reconstr Aesthet Surg 2024 Jan;88:24-32. Epub 2023 Oct 23 doi: 10.1016/j.bjps.2023.10.107. PMID: 37950988Free PMC Article
Nazari S, Vaezi A, Mossavarali S, Ghanavati K, Shafiee A
Eur J Pediatr 2024 Jan;183(1):73-82. Epub 2023 Nov 4 doi: 10.1007/s00431-023-05322-4. PMID: 37924347
Lee HJ, Yang IH, Baek SH
J Craniofac Surg 2021 Nov-Dec 01;32(8):e773-e778. doi: 10.1097/SCS.0000000000007769. PMID: 34727453
Moraleda-Cibrián M, Edwards S, Kasten S, Warschausky S, Buchman S, O'Brien L
Sleep Med 2021 Sep;85:303-308. Epub 2021 Jul 21 doi: 10.1016/j.sleep.2021.07.026. PMID: 34391005

Recent systematic reviews

Nazari S, Vaezi A, Mossavarali S, Ghanavati K, Shafiee A
Eur J Pediatr 2024 Jan;183(1):73-82. Epub 2023 Nov 4 doi: 10.1007/s00431-023-05322-4. PMID: 37924347

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