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Abnormal spleen physiology

MedGen UID:
1372718
Concept ID:
C4476762
Finding
HPO: HP:0025409

Definition

Any anomaly of the function of the spleen. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal spleen physiology

Professional guidelines

PubMed

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Morin G, Biancalana V, Echaniz-Laguna A, Noury JB, Lornage X, Moggio M, Ripolone M, Violano R, Marcorelles P, Maréchal D, Renaud F, Maurage CA, Tard C, Cuisset JM, Laporte J, Böhm J
Hum Mutat 2020 Jan;41(1):17-37. Epub 2019 Sep 15 doi: 10.1002/humu.23899. PMID: 31448844
Xu L, Feng J, Gao G, Tang H
Expert Opin Pharmacother 2019 Nov;20(16):1943-1951. Epub 2019 Aug 26 doi: 10.1080/14656566.2019.1657093. PMID: 31450973

Recent clinical studies

Etiology

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Wang L, Wang H, Luo J, Xie T, Mor G, Liao A
Theranostics 2022;12(17):7216-7236. Epub 2022 Oct 17 doi: 10.7150/thno.78467. PMID: 36438479Free PMC Article
Perrotta S, Gallagher PG, Mohandas N
Lancet 2008 Oct 18;372(9647):1411-26. doi: 10.1016/S0140-6736(08)61588-3. PMID: 18940465
Guggenbuhl P, Grosbois B, Chalès G
Joint Bone Spine 2008 Mar;75(2):116-24. Epub 2007 Aug 31 doi: 10.1016/j.jbspin.2007.06.006. PMID: 17996473

Diagnosis

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Bonfiglio F, Bruscaggin A, Guidetti F, Terzi di Bergamo L, Faderl M, Spina V, Condoluci A, Bonomini L, Forestieri G, Koch R, Piffaretti D, Pini K, Pirosa MC, Cittone MG, Arribas A, Lucioni M, Ghilardi G, Wu W, Arcaini L, Baptista MJ, Bastidas G, Bea S, Boldorini R, Broccoli A, Buehler MM, Canzonieri V, Cascione L, Ceriani L, Cogliatti S, Corradini P, Derenzini E, Devizzi L, Dietrich S, Elia AR, Facchetti F, Gaidano G, Garcia JF, Gerber B, Ghia P, Gomes da Silva M, Gritti G, Guidetti A, Hitz F, Inghirami G, Ladetto M, Lopez-Guillermo A, Lucchini E, Maiorana A, Marasca R, Matutes E, Meignin V, Merli M, Moccia A, Mollejo M, Montalban C, Novak U, Oscier DG, Passamonti F, Piazza F, Pizzolitto S, Rambaldi A, Sabattini E, Salles G, Santambrogio E, Scarfò L, Stathis A, Stüssi G, Geyer JT, Tapia G, Tarella C, Thieblemont C, Tousseyn T, Tucci A, Vanini G, Visco C, Vitolo U, Walewska R, Zaja F, Zenz T, Zinzani PL, Khiabanian H, Calcinotto A, Bertoni F, Bhagat G, Campo E, De Leval L, Dirnhofer S, Pileri SA, Piris MA, Traverse-Glehen A, Tzankov A, Paulli M, Ponzoni M, Mazzucchelli L, Cavalli F, Zucca E, Rossi D
Blood 2022 Feb 3;139(5):732-747. doi: 10.1182/blood.2021012386. PMID: 34653238
Elton TS, Selemon H, Elton SM, Parinandi NL
Gene 2013 Dec 10;532(1):1-12. Epub 2012 Dec 14 doi: 10.1016/j.gene.2012.12.009. PMID: 23246696
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172
Guggenbuhl P, Grosbois B, Chalès G
Joint Bone Spine 2008 Mar;75(2):116-24. Epub 2007 Aug 31 doi: 10.1016/j.jbspin.2007.06.006. PMID: 17996473

Therapy

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Xu L, Feng J, Gao G, Tang H
Expert Opin Pharmacother 2019 Nov;20(16):1943-1951. Epub 2019 Aug 26 doi: 10.1080/14656566.2019.1657093. PMID: 31450973
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172
Lipsker D
Orphanet J Rare Dis 2010 Dec 8;5:38. doi: 10.1186/1750-1172-5-38. PMID: 21143856Free PMC Article

Prognosis

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Bonfiglio F, Bruscaggin A, Guidetti F, Terzi di Bergamo L, Faderl M, Spina V, Condoluci A, Bonomini L, Forestieri G, Koch R, Piffaretti D, Pini K, Pirosa MC, Cittone MG, Arribas A, Lucioni M, Ghilardi G, Wu W, Arcaini L, Baptista MJ, Bastidas G, Bea S, Boldorini R, Broccoli A, Buehler MM, Canzonieri V, Cascione L, Ceriani L, Cogliatti S, Corradini P, Derenzini E, Devizzi L, Dietrich S, Elia AR, Facchetti F, Gaidano G, Garcia JF, Gerber B, Ghia P, Gomes da Silva M, Gritti G, Guidetti A, Hitz F, Inghirami G, Ladetto M, Lopez-Guillermo A, Lucchini E, Maiorana A, Marasca R, Matutes E, Meignin V, Merli M, Moccia A, Mollejo M, Montalban C, Novak U, Oscier DG, Passamonti F, Piazza F, Pizzolitto S, Rambaldi A, Sabattini E, Salles G, Santambrogio E, Scarfò L, Stathis A, Stüssi G, Geyer JT, Tapia G, Tarella C, Thieblemont C, Tousseyn T, Tucci A, Vanini G, Visco C, Vitolo U, Walewska R, Zaja F, Zenz T, Zinzani PL, Khiabanian H, Calcinotto A, Bertoni F, Bhagat G, Campo E, De Leval L, Dirnhofer S, Pileri SA, Piris MA, Traverse-Glehen A, Tzankov A, Paulli M, Ponzoni M, Mazzucchelli L, Cavalli F, Zucca E, Rossi D
Blood 2022 Feb 3;139(5):732-747. doi: 10.1182/blood.2021012386. PMID: 34653238
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172
Lonergan GJ, Cline DB, Abbondanzo SL
Radiographics 2001 Jul-Aug;21(4):971-94. doi: 10.1148/radiographics.21.4.g01jl23971. PMID: 11452073
Tavassoli M
West J Med 1975 Mar;122(3):194-8. PMID: 1096474Free PMC Article

Clinical prediction guides

Kaspy KR, Dell SD, Davis SD, Ferkol TW, Rosenfeld M, Sagel SD, Milla C, Olivier KN, Barber AT, Wee W, Lin FC, Li L, Rampakakis E, Zariwala MA, Knowles MR, Leigh MW, Shapiro AJ
Chest 2024 May;165(5):1070-1081. Epub 2023 Dec 9 doi: 10.1016/j.chest.2023.12.005. PMID: 38072392Free PMC Article
Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Luu S, Woolley IJ, Andrews RK
Platelets 2021 Jan 2;32(1):47-52. Epub 2020 Feb 27 doi: 10.1080/09537104.2020.1732322. PMID: 32106750
Jones SA, McGovern M, Lidove O, Giugliani R, Mistry PK, Dionisi-Vici C, Munoz-Rojas MV, Nalysnyk L, Schecter AD, Wasserstein M
Mol Genet Metab 2020 Sep-Oct;131(1-2):116-123. Epub 2020 Jun 24 doi: 10.1016/j.ymgme.2020.06.008. PMID: 32616389

Recent systematic reviews

Rankine-Mullings AE, Owusu-Ofori S
Cochrane Database Syst Rev 2021 Mar 8;3(3):CD003427. doi: 10.1002/14651858.CD003427.pub5. PMID: 33724440Free PMC Article

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