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Abnormal spleen physiology

MedGen UID:
1372718
Concept ID:
C4476762
Finding
HPO: HP:0025409

Definition

Any anomaly of the function of the spleen. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal spleen physiology

Professional guidelines

PubMed

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Rosato S, Unger S, Campos-Xavier B, Caraffi SG, Beltrami L, Pollazzon M, Ivanovski I, Castori M, Bonasoni MP, Comitini G, Nikkels PGJ, Lindstrom K, Umandap C, Superti-Furga A, Garavelli L
Genes (Basel) 2022 Jan 28;13(2) doi: 10.3390/genes13020261. PMID: 35205306Free PMC Article
Xu L, Feng J, Gao G, Tang H
Expert Opin Pharmacother 2019 Nov;20(16):1943-1951. Epub 2019 Aug 26 doi: 10.1080/14656566.2019.1657093. PMID: 31450973

Recent clinical studies

Etiology

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Wang L, Wang H, Luo J, Xie T, Mor G, Liao A
Theranostics 2022;12(17):7216-7236. Epub 2022 Oct 17 doi: 10.7150/thno.78467. PMID: 36438479Free PMC Article
Mann BK, Bhandohal JS, Cobos E, Chitturi C, Eppanapally S
J Investig Med 2022 Feb;70(2):348-353. Epub 2021 Nov 30 doi: 10.1136/jim-2021-002149. PMID: 34848562
Perrotta S, Gallagher PG, Mohandas N
Lancet 2008 Oct 18;372(9647):1411-26. doi: 10.1016/S0140-6736(08)61588-3. PMID: 18940465

Diagnosis

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Bonfiglio F, Bruscaggin A, Guidetti F, Terzi di Bergamo L, Faderl M, Spina V, Condoluci A, Bonomini L, Forestieri G, Koch R, Piffaretti D, Pini K, Pirosa MC, Cittone MG, Arribas A, Lucioni M, Ghilardi G, Wu W, Arcaini L, Baptista MJ, Bastidas G, Bea S, Boldorini R, Broccoli A, Buehler MM, Canzonieri V, Cascione L, Ceriani L, Cogliatti S, Corradini P, Derenzini E, Devizzi L, Dietrich S, Elia AR, Facchetti F, Gaidano G, Garcia JF, Gerber B, Ghia P, Gomes da Silva M, Gritti G, Guidetti A, Hitz F, Inghirami G, Ladetto M, Lopez-Guillermo A, Lucchini E, Maiorana A, Marasca R, Matutes E, Meignin V, Merli M, Moccia A, Mollejo M, Montalban C, Novak U, Oscier DG, Passamonti F, Piazza F, Pizzolitto S, Rambaldi A, Sabattini E, Salles G, Santambrogio E, Scarfò L, Stathis A, Stüssi G, Geyer JT, Tapia G, Tarella C, Thieblemont C, Tousseyn T, Tucci A, Vanini G, Visco C, Vitolo U, Walewska R, Zaja F, Zenz T, Zinzani PL, Khiabanian H, Calcinotto A, Bertoni F, Bhagat G, Campo E, De Leval L, Dirnhofer S, Pileri SA, Piris MA, Traverse-Glehen A, Tzankov A, Paulli M, Ponzoni M, Mazzucchelli L, Cavalli F, Zucca E, Rossi D
Blood 2022 Feb 3;139(5):732-747. doi: 10.1182/blood.2021012386. PMID: 34653238
Radu CC, Muţiu G, Pop O
Rom J Morphol Embryol 2014;55(3 Suppl):1243-6. PMID: 25607414
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172
Iolascon A, Avvisati RA, Piscopo C
Transfus Clin Biol 2010 Sep;17(3):138-42. Epub 2010 Jul 23 doi: 10.1016/j.tracli.2010.05.006. PMID: 20655264

Therapy

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Marín-Ramos NI, Thein TZ, Ghaghada KB, Chen TC, Giannotta SL, Hofman FM
Circ Res 2020 Oct 9;127(9):e210-e231. Epub 2020 Aug 5 doi: 10.1161/CIRCRESAHA.119.316317. PMID: 32755283
Xu L, Feng J, Gao G, Tang H
Expert Opin Pharmacother 2019 Nov;20(16):1943-1951. Epub 2019 Aug 26 doi: 10.1080/14656566.2019.1657093. PMID: 31450973
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172

Prognosis

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Bonfiglio F, Bruscaggin A, Guidetti F, Terzi di Bergamo L, Faderl M, Spina V, Condoluci A, Bonomini L, Forestieri G, Koch R, Piffaretti D, Pini K, Pirosa MC, Cittone MG, Arribas A, Lucioni M, Ghilardi G, Wu W, Arcaini L, Baptista MJ, Bastidas G, Bea S, Boldorini R, Broccoli A, Buehler MM, Canzonieri V, Cascione L, Ceriani L, Cogliatti S, Corradini P, Derenzini E, Devizzi L, Dietrich S, Elia AR, Facchetti F, Gaidano G, Garcia JF, Gerber B, Ghia P, Gomes da Silva M, Gritti G, Guidetti A, Hitz F, Inghirami G, Ladetto M, Lopez-Guillermo A, Lucchini E, Maiorana A, Marasca R, Matutes E, Meignin V, Merli M, Moccia A, Mollejo M, Montalban C, Novak U, Oscier DG, Passamonti F, Piazza F, Pizzolitto S, Rambaldi A, Sabattini E, Salles G, Santambrogio E, Scarfò L, Stathis A, Stüssi G, Geyer JT, Tapia G, Tarella C, Thieblemont C, Tousseyn T, Tucci A, Vanini G, Visco C, Vitolo U, Walewska R, Zaja F, Zenz T, Zinzani PL, Khiabanian H, Calcinotto A, Bertoni F, Bhagat G, Campo E, De Leval L, Dirnhofer S, Pileri SA, Piris MA, Traverse-Glehen A, Tzankov A, Paulli M, Ponzoni M, Mazzucchelli L, Cavalli F, Zucca E, Rossi D
Blood 2022 Feb 3;139(5):732-747. doi: 10.1182/blood.2021012386. PMID: 34653238
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172
Lonergan GJ, Cline DB, Abbondanzo SL
Radiographics 2001 Jul-Aug;21(4):971-94. doi: 10.1148/radiographics.21.4.g01jl23971. PMID: 11452073
Henneberry MO, Engel G, Grayhack JT
Urol Clin North Am 1979 Oct;6(3):629-41. PMID: 388794

Clinical prediction guides

Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Wang C, Zhang W, Xu W, Liu Z, Huang K
Clin Transl Med 2022 May;12(5):e854. doi: 10.1002/ctm2.854. PMID: 35538889Free PMC Article
Luu S, Woolley IJ, Andrews RK
Platelets 2021 Jan 2;32(1):47-52. Epub 2020 Feb 27 doi: 10.1080/09537104.2020.1732322. PMID: 32106750
Jones SA, McGovern M, Lidove O, Giugliani R, Mistry PK, Dionisi-Vici C, Munoz-Rojas MV, Nalysnyk L, Schecter AD, Wasserstein M
Mol Genet Metab 2020 Sep-Oct;131(1-2):116-123. Epub 2020 Jun 24 doi: 10.1016/j.ymgme.2020.06.008. PMID: 32616389

Recent systematic reviews

Rankine-Mullings AE, Owusu-Ofori S
Cochrane Database Syst Rev 2021 Mar 8;3(3):CD003427. doi: 10.1002/14651858.CD003427.pub5. PMID: 33724440Free PMC Article

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