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Abnormal liver sonography

MedGen UID:
1374725
•Concept ID:
C4476999
•
Finding
HPO: HP:0031140

Definition

An abnormal appearance of the liver or any of its components on sonography (ultrasound). [from HPO]

Professional guidelines

PubMed

ACG Clinical Guideline: Diagnosis and Management of Biliary Strictures.
Elmunzer BJ, Maranki JL, Gómez V, Tavakkoli A, Sauer BG, Limketkai BN, Brennan EA, Attridge EM, Brigham TJ, Wang AY
Am J Gastroenterol 2023 Mar 1;118(3):405-426. Epub 2023 Jan 17 doi: 10.14309/ajg.0000000000002190. PMID: 36863037
Hepatorenal syndrome: pathophysiology, diagnosis, and management.
Simonetto DA, Gines P, Kamath PS
BMJ 2020 Sep 14;370:m2687. doi: 10.1136/bmj.m2687. PMID: 32928750
Cirrhosis: Diagnosis and Management.
Smith A, Baumgartner K, Bositis C
Am Fam Physician 2019 Dec 15;100(12):759-770. PMID: 31845776

Recent clinical studies

Etiology

Development and validation of a model for early diagnosis of biliary atresia.
Gong Z, Lin L, Lu G, Wan C
BMC Pediatr 2023 Oct 31;23(1):549. doi: 10.1186/s12887-023-04370-x. PMID: 37907911Free PMC Article
Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.
Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324
Neonatal Jaundice.
Abbey P, Kandasamy D, Naranje P
Indian J Pediatr 2019 Sep;86(9):830-841. Epub 2019 Feb 21 doi: 10.1007/s12098-019-02856-0. PMID: 30790186
Neonatal cancer.
Orbach D, Sarnacki S, Brisse HJ, Gauthier-Villars M, Jarreau PH, Tsatsaris V, Baruchel A, Zerah M, Seigneur E, Peuchmaur M, Doz F
Lancet Oncol 2013 Dec;14(13):e609-20. doi: 10.1016/S1470-2045(13)70236-5. PMID: 24275134
Meckel syndrome.
Salonen R, Paavola P
J Med Genet 1998 Jun;35(6):497-501. doi: 10.1136/jmg.35.6.497. PMID: 9643292Free PMC Article

Diagnosis

Microvascular Flow Imaging: A State-of-the-Art Review of Clinical Use and Promise.
Aziz MU, Eisenbrey JR, Deganello A, Zahid M, Sharbidre K, Sidhu P, Robbin ML
Radiology 2022 Nov;305(2):250-264. Epub 2022 Sep 27 doi: 10.1148/radiol.213303. PMID: 36165794Free PMC Article
Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.
Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324
Endoscopic Ultrasound-guided Liver Biopsy.
Diehl DL
Gastrointest Endosc Clin N Am 2019 Apr;29(2):173-186. Epub 2019 Feb 2 doi: 10.1016/j.giec.2018.11.002. PMID: 30846147
Neonatal Jaundice.
Abbey P, Kandasamy D, Naranje P
Indian J Pediatr 2019 Sep;86(9):830-841. Epub 2019 Feb 21 doi: 10.1007/s12098-019-02856-0. PMID: 30790186
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637

Therapy

Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study.
Harrison SA, Ratziu V, Boursier J, Francque S, Bedossa P, Majd Z, Cordonnier G, Sudrik FB, Darteil R, Liebe R, Magnanensi J, Hajji Y, Brozek J, Roudot A, Staels B, Hum DW, Megnien SJ, Hosmane S, Dam N, Chaumat P, Hanf R, Anstee QM, Sanyal AJ
Lancet Gastroenterol Hepatol 2020 Nov;5(11):970-985. Epub 2020 Aug 5 doi: 10.1016/S2468-1253(20)30252-1. PMID: 32763196
Autosomal dominant polycystic kidney disease.
Cornec-Le Gall E, Alam A, Perrone RD
Lancet 2019 Mar 2;393(10174):919-935. Epub 2019 Feb 25 doi: 10.1016/S0140-6736(18)32782-X. PMID: 30819518
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Normal splenic size in infants and children: sonographic measurements.
Rosenberg HK, Markowitz RI, Kolberg H, Park C, Hubbard A, Bellah RD
AJR Am J Roentgenol 1991 Jul;157(1):119-21. doi: 10.2214/ajr.157.1.2048509. PMID: 2048509

Prognosis

Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.
Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Biliary atresia.
Baumann U, Ure B
Clin Res Hepatol Gastroenterol 2012 Jun;36(3):257-9. Epub 2012 May 18 doi: 10.1016/j.clinre.2012.03.017. PMID: 22609296
Intestinal atresia.
Prasad TR, Bajpai M
Indian J Pediatr 2000 Sep;67(9):671-8. doi: 10.1007/BF02762182. PMID: 11028122

Clinical prediction guides

Development and validation of a model for early diagnosis of biliary atresia.
Gong Z, Lin L, Lu G, Wan C
BMC Pediatr 2023 Oct 31;23(1):549. doi: 10.1186/s12887-023-04370-x. PMID: 37907911Free PMC Article
A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study.
Harrison SA, Ratziu V, Boursier J, Francque S, Bedossa P, Majd Z, Cordonnier G, Sudrik FB, Darteil R, Liebe R, Magnanensi J, Hajji Y, Brozek J, Roudot A, Staels B, Hum DW, Megnien SJ, Hosmane S, Dam N, Chaumat P, Hanf R, Anstee QM, Sanyal AJ
Lancet Gastroenterol Hepatol 2020 Nov;5(11):970-985. Epub 2020 Aug 5 doi: 10.1016/S2468-1253(20)30252-1. PMID: 32763196
Prenatal diagnosis, imaging, and prognosis in Congenital Diaphragmatic Hernia.
Cordier AG, Russo FM, Deprest J, Benachi A
Semin Perinatol 2020 Feb;44(1):51163. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.002. PMID: 31439324
Imaging in pediatric liver transplantation.
Monti L, Soglia G, Tomà P
Radiol Med 2016 May;121(5):378-90. Epub 2016 Feb 24 doi: 10.1007/s11547-016-0628-3. PMID: 26909515
Intestinal atresia.
Prasad TR, Bajpai M
Indian J Pediatr 2000 Sep;67(9):671-8. doi: 10.1007/BF02762182. PMID: 11028122

Recent systematic reviews

Performance of two-dimensional shear wave elastography for detecting advanced liver fibrosis and cirrhosis in patients with biliary atresia: a systematic review and meta-analysis.
Dong B, Duan Y, Wang H, Chen Y, Lyu G
Pediatr Radiol 2023 Dec;53(13):2642-2650. Epub 2023 Nov 2 doi: 10.1007/s00247-023-05796-2. PMID: 37917168
Applications of elastography in operative neurosurgery: A systematic review.
Hersh AM, Weber-Levine C, Jiang K, Young L, Kerensky M, Routkevitch D, Tsehay Y, Perdomo-Pantoja A, Judy BF, Lubelski D, Theodore N, Manbachi A
J Clin Neurosci 2022 Oct;104:18-28. Epub 2022 Aug 4 doi: 10.1016/j.jocn.2022.07.019. PMID: 35933785Free PMC Article
Guidelines-similarities and dissimilarities: a systematic review of international clinical practice guidelines for pregnancy hypertension.
Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743
Diagnosis and Prevalence of Cirrhotic Cardiomyopathy: A Systematic Review and Meta-analysis.
Shahvaran SA, Menyhárt O, Csedrik L, Patai ÁV
Curr Probl Cardiol 2021 Oct;46(10):100821. Epub 2021 Feb 24 doi: 10.1016/j.cpcardiol.2021.100821. PMID: 34016482
Outcomes associated with fetal hepatobiliary cysts: systematic review and meta-analysis.
Leombroni M, Buca D, Celentano C, Liberati M, Bascietto F, Gustapane S, Marrone L, Manzoli L, Rizzo G, D'Antonio F
Ultrasound Obstet Gynecol 2017 Aug;50(2):167-174. Epub 2017 Jul 9 doi: 10.1002/uog.17244. PMID: 27553859

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