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Spastic cerebral palsy

MedGen UID:
137905
•Concept ID:
C0338596
•
Disease or Syndrome
Synonyms: Cerebral Palsy, Spastic; Spastic Cerebral Palsies; Spastic Cerebral Palsy
SNOMED CT: Pyramidal cerebral palsy (230773005); Congenital spastic paralysis (230773005); Spastic infantile paralysis (230773005); Little's disease (230773005); Infantile spastic cerebral palsy (230773005); Congenital spastic cerebral palsy (230773005); Spastic cerebral palsy (230773005)
 
Monarch Initiative: MONDO:0000396

Definition

A type of cerebral palsy defined by increased tone and pathological reflexes resulting in an abnormal pattern of movement and posture. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Spastic cerebral palsy

Professional guidelines

PubMed

Efficacy of conservative treatment for spastic cerebral palsy children with equinus gait: a systematic review and meta-analysis.
Klaewkasikum K, Patathong T, Woratanarat P, Woratanarat T, Thadanipon K, Rattanasiri S, Thakkinstian A
J Orthop Surg Res 2022 Sep 8;17(1):411. doi: 10.1186/s13018-022-03301-3. PMID: 36076293Free PMC Article
Tone Reduction and Physical Therapy: Strengthening Partners in Treatment of Children with Spastic Cerebral Palsy.
Franki I, Bar-On L, Molenaers G, Van Campenhout A, Craenen K, Desloovere K, Feys H, Pauwels P, De Cat J, Ortibus E
Neuropediatrics 2020 Apr;51(2):89-104. Epub 2019 Nov 27 doi: 10.1055/s-0039-3400987. PMID: 31777043
Selection of treatment modalities in children with spastic cerebral palsy.
Steinbok P
Neurosurg Focus 2006 Aug 15;21(2):e4. doi: 10.3171/foc.2006.21.2.5. PMID: 16918225

Recent clinical studies

Etiology

Acute Effects of Static and Proprioceptive Neuromuscular Facilitation Stretching of the Plantar Flexors on Ankle Range of Motion and Muscle-Tendon Behavior in Children with Spastic Cerebral Palsy-A Randomized Clinical Trial.
Kruse A, Habersack A, Jaspers RT, Schrapf N, Weide G, Svehlik M, Tilp M
Int J Environ Res Public Health 2022 Sep 15;19(18) doi: 10.3390/ijerph191811599. PMID: 36141875Free PMC Article
Effect of muscle strength training in children and adolescents with spastic cerebral palsy: A systematic review and meta-analysis.
Merino-Andrés J, García de Mateos-López A, Damiano DL, Sánchez-Sierra A
Clin Rehabil 2022 Jan;36(1):4-14. Epub 2021 Aug 18 doi: 10.1177/02692155211040199. PMID: 34407619Free PMC Article
Cerebral palsy: Aetiology, pathophysiology and therapeutic interventions.
Upadhyay J, Tiwari N, Ansari MN
Clin Exp Pharmacol Physiol 2020 Dec;47(12):1891-1901. Epub 2020 Aug 19 doi: 10.1111/1440-1681.13379. PMID: 32662125
A Critical Evaluation of Current Concepts in Cerebral Palsy.
Brandenburg JE, Fogarty MJ, Sieck GC
Physiology (Bethesda) 2019 May 1;34(3):216-229. doi: 10.1152/physiol.00054.2018. PMID: 30968751Free PMC Article
Pediatric aquatic therapy on motor function and enjoyment in children diagnosed with cerebral palsy of various motor severities.
Lai CJ, Liu WY, Yang TF, Chen CL, Wu CY, Chan RC
J Child Neurol 2015 Feb;30(2):200-8. Epub 2014 Jun 5 doi: 10.1177/0883073814535491. PMID: 24907137

Diagnosis

Effects of 8 weeks functional training programme on posture control and functional mobility in spastic hemiplegic cerebral palsy.
Gulzar A, Waris M; Qurat Ul Ain
J Pak Med Assoc 2022 Jul;72(7):1278-1281. doi: 10.47391/JPMA.3476. PMID: 36156543
Cerebral palsy: Aetiology, pathophysiology and therapeutic interventions.
Upadhyay J, Tiwari N, Ansari MN
Clin Exp Pharmacol Physiol 2020 Dec;47(12):1891-1901. Epub 2020 Aug 19 doi: 10.1111/1440-1681.13379. PMID: 32662125
A Critical Evaluation of Current Concepts in Cerebral Palsy.
Brandenburg JE, Fogarty MJ, Sieck GC
Physiology (Bethesda) 2019 May 1;34(3):216-229. doi: 10.1152/physiol.00054.2018. PMID: 30968751Free PMC Article
Pediatric aquatic therapy on motor function and enjoyment in children diagnosed with cerebral palsy of various motor severities.
Lai CJ, Liu WY, Yang TF, Chen CL, Wu CY, Chan RC
J Child Neurol 2015 Feb;30(2):200-8. Epub 2014 Jun 5 doi: 10.1177/0883073814535491. PMID: 24907137
Dandy-Walker syndrome revisited.
Maria BL, Zinreich SJ, Carson BC, Rosenbaum AE, Freeman JM
Pediatr Neurosci 1987;13(1):45-51. doi: 10.1159/000120300. PMID: 3684815

Therapy

Effects of 8 weeks functional training programme on posture control and functional mobility in spastic hemiplegic cerebral palsy.
Gulzar A, Waris M; Qurat Ul Ain
J Pak Med Assoc 2022 Jul;72(7):1278-1281. doi: 10.47391/JPMA.3476. PMID: 36156543
Acute Effects of Static and Proprioceptive Neuromuscular Facilitation Stretching of the Plantar Flexors on Ankle Range of Motion and Muscle-Tendon Behavior in Children with Spastic Cerebral Palsy-A Randomized Clinical Trial.
Kruse A, Habersack A, Jaspers RT, Schrapf N, Weide G, Svehlik M, Tilp M
Int J Environ Res Public Health 2022 Sep 15;19(18) doi: 10.3390/ijerph191811599. PMID: 36141875Free PMC Article
Effect of muscle strength training in children and adolescents with spastic cerebral palsy: A systematic review and meta-analysis.
Merino-Andrés J, García de Mateos-López A, Damiano DL, Sánchez-Sierra A
Clin Rehabil 2022 Jan;36(1):4-14. Epub 2021 Aug 18 doi: 10.1177/02692155211040199. PMID: 34407619Free PMC Article
Pediatric aquatic therapy on motor function and enjoyment in children diagnosed with cerebral palsy of various motor severities.
Lai CJ, Liu WY, Yang TF, Chen CL, Wu CY, Chan RC
J Child Neurol 2015 Feb;30(2):200-8. Epub 2014 Jun 5 doi: 10.1177/0883073814535491. PMID: 24907137
Hand-arm bimanual intensive therapy including lower extremities (HABIT-ILE) for children with cerebral palsy.
Bleyenheuft Y, Gordon AM
Phys Occup Ther Pediatr 2014 Nov;34(4):390-403. Epub 2014 Oct 1 doi: 10.3109/01942638.2014.932884. PMID: 25271469

Prognosis

Action Observation Training to Improve Upper Limb Function in Infants with Unilateral Brain Lesion - a Feasibility Study.
von Gunten M, Botros A, Tobler-Ammann B, Nef T, Grunt S
Dev Neurorehabil 2023 May;26(4):234-243. Epub 2023 Mar 22 doi: 10.1080/17518423.2023.2193630. PMID: 36949659
Plantar grasp reflex in high-risk infants during the first year of life.
Zafeiriou DI
Pediatr Neurol 2000 Jan;22(1):75-6. doi: 10.1016/s0887-8994(99)00110-1. PMID: 10669212
Complications with selective posterior rhizotomy.
Abbott R
Pediatr Neurosurg 1992;18(1):43-7. doi: 10.1159/000120640. PMID: 1419841
Dandy-Walker syndrome revisited.
Maria BL, Zinreich SJ, Carson BC, Rosenbaum AE, Freeman JM
Pediatr Neurosci 1987;13(1):45-51. doi: 10.1159/000120300. PMID: 3684815
Cavus foot in cerebral palsy.
Eilert RE
Foot Ankle 1984 Jan-Feb;4(4):185-7. doi: 10.1177/107110078400400404. PMID: 6714859

Clinical prediction guides

Acute Effects of Static and Proprioceptive Neuromuscular Facilitation Stretching of the Plantar Flexors on Ankle Range of Motion and Muscle-Tendon Behavior in Children with Spastic Cerebral Palsy-A Randomized Clinical Trial.
Kruse A, Habersack A, Jaspers RT, Schrapf N, Weide G, Svehlik M, Tilp M
Int J Environ Res Public Health 2022 Sep 15;19(18) doi: 10.3390/ijerph191811599. PMID: 36141875Free PMC Article
Effect of position on gross motor function and spasticity in spastic cerebral palsy children.
Rauf W, Sarmad S, Khan I, Jawad M
J Pak Med Assoc 2021 Mar;71(3):801-805. doi: 10.47391/JPMA.1213. PMID: 34057924
Randomised trial of virtual reality gaming and physiotherapy on balance, gross motor performance and daily functions among children with bilateral spastic cerebral palsy.
Jha KK, Karunanithi GB, Sahana A, Karthikbabu S
Somatosens Mot Res 2021 Jun;38(2):117-126. Epub 2021 Mar 3 doi: 10.1080/08990220.2021.1876016. PMID: 33655813
Pediatric aquatic therapy on motor function and enjoyment in children diagnosed with cerebral palsy of various motor severities.
Lai CJ, Liu WY, Yang TF, Chen CL, Wu CY, Chan RC
J Child Neurol 2015 Feb;30(2):200-8. Epub 2014 Jun 5 doi: 10.1177/0883073814535491. PMID: 24907137
Effects of hippotherapy on gross motor function and functional performance of children with cerebral palsy.
Park ES, Rha DW, Shin JS, Kim S, Jung S
Yonsei Med J 2014 Nov;55(6):1736-42. doi: 10.3349/ymj.2014.55.6.1736. PMID: 25323914Free PMC Article

Recent systematic reviews

The Impact of Functional Strength Training on Muscle Strength and Mobility in Children with Spastic Cerebral Palsy - A Systematic Review and Meta-Analysis.
Shilesh K, Karthikbabu S, Rao PT
Dev Neurorehabil 2023 May;26(4):262-277. Epub 2023 May 30 doi: 10.1080/17518423.2023.2218905. PMID: 37254274
Efficacy of conservative treatment for spastic cerebral palsy children with equinus gait: a systematic review and meta-analysis.
Klaewkasikum K, Patathong T, Woratanarat P, Woratanarat T, Thadanipon K, Rattanasiri S, Thakkinstian A
J Orthop Surg Res 2022 Sep 8;17(1):411. doi: 10.1186/s13018-022-03301-3. PMID: 36076293Free PMC Article
Effect of muscle strength training in children and adolescents with spastic cerebral palsy: A systematic review and meta-analysis.
Merino-Andrés J, García de Mateos-López A, Damiano DL, Sánchez-Sierra A
Clin Rehabil 2022 Jan;36(1):4-14. Epub 2021 Aug 18 doi: 10.1177/02692155211040199. PMID: 34407619Free PMC Article
Motor Cortex Plasticity in Children With Spastic Cerebral Palsy: A Systematic Review.
de Almeida Carvalho Duarte N, Collange Grecco LA, Zanon N, Galli M, Fregni F, Santos Oliveira C
J Mot Behav 2017 Jul-Aug;49(4):355-364. Epub 2016 Oct 18 doi: 10.1080/00222895.2016.1219310. PMID: 27754798
Gross muscle morphology and structure in spastic cerebral palsy: a systematic review.
Barrett RS, Lichtwark GA
Dev Med Child Neurol 2010 Sep;52(9):794-804. Epub 2010 Apr 30 doi: 10.1111/j.1469-8749.2010.03686.x. PMID: 20477832

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