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Eyelid seborrheic keratosis

MedGen UID:
137912
•Concept ID:
C0339109
•
Neoplastic Process
Synonyms: Basal cell papilloma of eyelid; Basal Cell Papilloma of Eyelid; basal cell papilloma of eyelid; Basal Cell Papilloma of the Eyelid; basal cell papilloma of the eyelid; Eyelid Basal Cell Papilloma; eyelid basal cell papilloma; Eyelid Seborrheic Keratosis; eyelid seborrheic keratosis; Seborrheic keratosis of eyelid; Seborrheic Keratosis of Eyelid; seborrheic keratosis of eyelid; Seborrheic Keratosis of the Eyelid; seborrheic keratosis of the eyelid
SNOMED CT: Basal cell papilloma of eyelid (231826004); Seborrheic keratosis of eyelid (231826004)
 
Monarch Initiative: MONDO:0021607

Definition

A benign skin neoplasm that arises from the eyelid. It is characterized by the intraepidermal proliferation of basaloid keratinocytes, acanthosis, hyperkeratosis, and cysts formation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEyelid seborrheic keratosis

Professional guidelines

PubMed

Evaluation and management of benign tumors of the eye and eyelid.
Brown R, Fard S, Feng P, Kerr PE
Clin Dermatol 2024 Jul-Aug;42(4):343-350. Epub 2024 Jan 26 doi: 10.1016/j.clindermatol.2024.01.005. PMID: 38281689
Q-switched ruby laser treatment of tattoos and benign pigmented skin lesions: a critical review.
Raulin C, Schönermark MP, Greve B, Werner S
Ann Plast Surg 1998 Nov;41(5):555-65. doi: 10.1097/00000637-199811000-00018. PMID: 9827962

Recent clinical studies

Etiology

Comparison of the clinical characteristics of benign and malignant eyelid lesions: an analysis of 1423 eyelid lesions, compared between ophthalmology department and plastics department.
Levinkron O, Schwalb L, Shoufani A, Gutovitz J, Krausz J, Briscoe D
Graefes Arch Clin Exp Ophthalmol 2024 Feb;262(2):615-621. Epub 2023 Oct 2 doi: 10.1007/s00417-023-06244-5. PMID: 37782346
Clinicopathological analysis of eyelid lesions in Sri Lanka.
Nanayakkara DPS, Dissanayake MM, Gunaratne MP, Soysa VK, Mathangasinghe Y
Int Ophthalmol 2023 Jul;43(7):2513-2519. Epub 2023 Mar 7 doi: 10.1007/s10792-023-02651-z. PMID: 36881193
Screening and Intervention for Skin Cancer in the Galapagos.
Ayasse MT, Marquez JE, Lozeau DF, Slutsky JB, Kaufmann TL, Lee Y, Scriven RJ, Dagum AB
Ann Plast Surg 2020 Jul;85(S1 Suppl 1):S143-S148. doi: 10.1097/SAP.0000000000002345. PMID: 32355081
Cutaneous Horn of the Eyelid in 13 Cases.
Pointdujour-Lim R, Marous MR, Satija CE, Douglass AM, Eagle RC Jr, Shields JA, Shields CL
Ophthalmic Plast Reconstr Surg 2017 Jul/Aug;33(4):233-236. doi: 10.1097/IOP.0000000000000816. PMID: 27811637
Eyelid tumours and pseudotumours in Hong Kong: a ten-year experience.
Ho M, Liu DT, Chong KK, Ng HK, Lam DS
Hong Kong Med J 2013 Apr;19(2):150-5. PMID: 23535675

Diagnosis

Evaluation and management of benign tumors of the eye and eyelid.
Brown R, Fard S, Feng P, Kerr PE
Clin Dermatol 2024 Jul-Aug;42(4):343-350. Epub 2024 Jan 26 doi: 10.1016/j.clindermatol.2024.01.005. PMID: 38281689
Clinicopathological analysis of eyelid lesions in Sri Lanka.
Nanayakkara DPS, Dissanayake MM, Gunaratne MP, Soysa VK, Mathangasinghe Y
Int Ophthalmol 2023 Jul;43(7):2513-2519. Epub 2023 Mar 7 doi: 10.1007/s10792-023-02651-z. PMID: 36881193
Pigmented Inflamed Seborrheic Keratosis of the Bulbar Conjunctiva.
Charles NC, Belinsky I
Ophthalmic Plast Reconstr Surg 2023 May-Jun 01;39(3):e89-e91. Epub 2023 Feb 21 doi: 10.1097/IOP.0000000000002346. PMID: 36806147
Screening and Intervention for Skin Cancer in the Galapagos.
Ayasse MT, Marquez JE, Lozeau DF, Slutsky JB, Kaufmann TL, Lee Y, Scriven RJ, Dagum AB
Ann Plast Surg 2020 Jul;85(S1 Suppl 1):S143-S148. doi: 10.1097/SAP.0000000000002345. PMID: 32355081
Cutaneous Horn of the Eyelid in 13 Cases.
Pointdujour-Lim R, Marous MR, Satija CE, Douglass AM, Eagle RC Jr, Shields JA, Shields CL
Ophthalmic Plast Reconstr Surg 2017 Jul/Aug;33(4):233-236. doi: 10.1097/IOP.0000000000000816. PMID: 27811637

Prognosis

Comparison of the Clinical Characteristics and Outcome of Benign and Malignant Eyelid Tumors: An Analysis of 4521 Eyelid Tumors in a Tertiary Medical Center.
Huang YY, Liang WY, Tsai CC, Kao SC, Yu WK, Kau HC, Liu CJ
Biomed Res Int 2015;2015:453091. Epub 2015 Nov 8 doi: 10.1155/2015/453091. PMID: 26634208Free PMC Article
Eyelid tumours and pseudotumours in Hong Kong: a ten-year experience.
Ho M, Liu DT, Chong KK, Ng HK, Lam DS
Hong Kong Med J 2013 Apr;19(2):150-5. PMID: 23535675
Seborrheic keratosis of the conjunctiva: a case report.
Kim JH, Bae HW, Lee KK, Kim TI, Kim EK
Korean J Ophthalmol 2009 Dec;23(4):306-8. Epub 2009 Dec 4 doi: 10.3341/kjo.2009.23.4.306. PMID: 20046694Free PMC Article
Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature.
Deprez M, Uffer S
Am J Dermatopathol 2009 May;31(3):256-62. doi: 10.1097/DAD.0b013e3181961861. PMID: 19384066
Glycopathological study of eyelid tumors and pseudotumors.
Uehara F, Yonezawa S, Sato E, Ohba N
Jpn J Ophthalmol 1997 Nov-Dec;41(6):362-9. doi: 10.1016/s0021-5155(97)00075-0. PMID: 9509302

Clinical prediction guides

THE INFLUENCE OF THE DEMODEX MITE ON THE MORPHOLOGICAL PICTURE OF EYELID PAPILLOMA.
Artemov O, Lytvynenko M, Chumachenko I, Bondarenko A, Dotsenko N, Ostapchuk K, Koshelnyk O, Gargin V
Georgian Med News 2024 Jul-Aug;(352-353):50-54. PMID: 39441269
Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature.
Deprez M, Uffer S
Am J Dermatopathol 2009 May;31(3):256-62. doi: 10.1097/DAD.0b013e3181961861. PMID: 19384066

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