U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Polyp of frontal sinus

MedGen UID:
137927
•Concept ID:
C0339814
•
Neoplastic Process
Synonyms: Frontal sinus polyp; Frontal Sinus Polyp; frontal sinus polyp; Polyp of Frontal Sinus; polyp of frontal sinus; Polyp of the Frontal Sinus; polyp of the frontal sinus
SNOMED CT: Polyp of frontal sinus (195759002); Frontal sinus polyp (195759002)
 
Monarch Initiative: MONDO:0021408

Definition

A polyp that arises from the frontal sinus mucosa. It is characterized by the presence of edematous tissue infiltrated by inflammatory cells, including eosinophils. Causes include allergic rhinitis, chronic sinusitis, and cystic fibrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolyp of frontal sinus

Professional guidelines

PubMed

Clinical Consensus Statement: Balloon Dilation of the Sinuses.
Piccirillo JF, Payne SC, Rosenfeld RM, Baroody FM, Batra PS, DelGaudio JM, Edelstein DR, Lane AP, Luong AU, Manes RP, McCoul ED, Platt MP, Reh DD, Corrigan MD
Otolaryngol Head Neck Surg 2018 Feb;158(2):203-214. doi: 10.1177/0194599817750086. PMID: 29389303
Evaluation of a Minimally Disruptive Treatment Protocol for Frontal Sinus Fractures.
Patel SA, Berens AM, Devarajan K, Whipple ME, Moe KS
JAMA Facial Plast Surg 2017 May 1;19(3):225-231. doi: 10.1001/jamafacial.2016.1769. PMID: 28152148Free PMC Article
Recognition and management of sinusitis.
Evans KL
Drugs 1998 Jul;56(1):59-71. doi: 10.2165/00003495-199856010-00006. PMID: 9664199

Recent clinical studies

Etiology

Advances in Sinus Surgery for Nasal Polyps.
Norwood TG, Grayson JW, Woodworth BA
Am J Rhinol Allergy 2023 Mar;37(2):162-167. doi: 10.1177/19458924221147783. PMID: 36848271
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
The role of frontal sinus drillouts in nasal polyposis.
Orgain CA, Harvey RJ
Curr Opin Otolaryngol Head Neck Surg 2018 Feb;26(1):34-40. doi: 10.1097/MOO.0000000000000425. PMID: 29095709
Chapter 8: Rhinosinusitis.
Georgy MS, Peters AT
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:24-27. doi: 10.2500/aap.2012.33.3538. PMID: 22794681
Long-term frontal sinus patency after endoscopic frontal sinusotomy.
Chan Y, Melroy CT, Kuhn CA, Kuhn FL, Daniel WT, Kuhn FA
Laryngoscope 2009 Jun;119(6):1229-32. doi: 10.1002/lary.20168. PMID: 19365848

Diagnosis

Volumetric study of the maxillary sinus in patients with sinus pathology.
Pérez Sayáns M, Suárez Quintanilla JA, Chamorro Petronacci CM, Suárez Peñaranda JM, López Jornet P, Gómez García F, Guerrero Sánchez Y
PLoS One 2020;15(6):e0234915. Epub 2020 Jun 18 doi: 10.1371/journal.pone.0234915. PMID: 32555640Free PMC Article
Clinical Consensus Statement: Balloon Dilation of the Sinuses.
Piccirillo JF, Payne SC, Rosenfeld RM, Baroody FM, Batra PS, DelGaudio JM, Edelstein DR, Lane AP, Luong AU, Manes RP, McCoul ED, Platt MP, Reh DD, Corrigan MD
Otolaryngol Head Neck Surg 2018 Feb;158(2):203-214. doi: 10.1177/0194599817750086. PMID: 29389303
The role of frontal sinus drillouts in nasal polyposis.
Orgain CA, Harvey RJ
Curr Opin Otolaryngol Head Neck Surg 2018 Feb;26(1):34-40. doi: 10.1097/MOO.0000000000000425. PMID: 29095709
Chronic Rhinosinusitis in Patients with Cystic Fibrosis.
Hamilos DL
J Allergy Clin Immunol Pract 2016 Jul-Aug;4(4):605-12. doi: 10.1016/j.jaip.2016.04.013. PMID: 27393775
Chapter 8: Rhinosinusitis.
Georgy MS, Peters AT
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:24-27. doi: 10.2500/aap.2012.33.3538. PMID: 22794681

Therapy

Frontal sinus stenting in endoscopic sinus surgery: the 10-year Oxford experience.
Bandino F, Pendolino A, Bates J, Qureishi A, Martinez-Devesa P
J Laryngol Otol 2024 Jan;138(1):60-66. Epub 2023 Apr 5 doi: 10.1017/S0022215123000622. PMID: 37016772
Use of intraoperative frontal sinus mometasone-eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps.
Schneider AL, Racette SD, Kang AK, Reddy AT, Huang JH, Lehmann DS, Price CPE, Eide JG, Rodeghiero SR, Conley DB, Welch KC, Kern RC, Shintani-Smith S, Peters AT, Kato A, Stevens WS, Schleimer RP, Tan BK
Int Forum Allergy Rhinol 2022 Nov;12(11):1330-1339. Epub 2022 May 19 doi: 10.1002/alr.23005. PMID: 35362251Free PMC Article
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
Ophthalmic complications of endoscopic sinus surgery.
Seredyka-Burduk M, Burduk PK, Wierzchowska M, Kaluzny B, Malukiewicz G
Braz J Otorhinolaryngol 2017 May-Jun;83(3):318-323. Epub 2016 May 4 doi: 10.1016/j.bjorl.2016.04.006. PMID: 27233691Free PMC Article
Frontal sinus irrigation: indications, results, and complications.
Klossek JM, Fontanel JP
Otolaryngol Clin North Am 2001 Feb;34(1):91-100. doi: 10.1016/s0030-6665(05)70297-8. PMID: 11344064

Prognosis

Radiopathologic predictors of 1- and 2-year frontal sinusotomy outcomes in a southeast Asian chronic rhinosinusitis population.
Chee J, Ong YK, Seet JE, Xu X
Eur Arch Otorhinolaryngol 2023 Nov;280(11):4915-4921. Epub 2023 May 30 doi: 10.1007/s00405-023-08048-z. PMID: 37249594
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
The role of frontal sinus drillouts in nasal polyposis.
Orgain CA, Harvey RJ
Curr Opin Otolaryngol Head Neck Surg 2018 Feb;26(1):34-40. doi: 10.1097/MOO.0000000000000425. PMID: 29095709
Long-term frontal sinus patency after endoscopic frontal sinusotomy.
Chan Y, Melroy CT, Kuhn CA, Kuhn FL, Daniel WT, Kuhn FA
Laryngoscope 2009 Jun;119(6):1229-32. doi: 10.1002/lary.20168. PMID: 19365848
Mucoceles of the frontal sinus. Clinical and therapeutical considerations.
Gavioli C, Grasso DL, Carinci F, Amoroso C, Pastore A
Minerva Stomatol 2002 Sep;51(9):385-90. PMID: 12473975

Clinical prediction guides

The relationship of sinus opacification, olfaction and dupilumab efficacy in patients with CRSwNP.
Lee SE, Amin N, Mannent LP, Bachert C, Gross G, Cho SH, Praestgaard A, Siddiqui S, Nash S, Kamat S, Khan AH, Jacob Nara JA
Rhinology 2023 Dec 1;61(6):531-540. doi: 10.4193/Rhin22.220. PMID: 37453138
Radiopathologic predictors of 1- and 2-year frontal sinusotomy outcomes in a southeast Asian chronic rhinosinusitis population.
Chee J, Ong YK, Seet JE, Xu X
Eur Arch Otorhinolaryngol 2023 Nov;280(11):4915-4921. Epub 2023 May 30 doi: 10.1007/s00405-023-08048-z. PMID: 37249594
Use of intraoperative frontal sinus mometasone-eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps.
Schneider AL, Racette SD, Kang AK, Reddy AT, Huang JH, Lehmann DS, Price CPE, Eide JG, Rodeghiero SR, Conley DB, Welch KC, Kern RC, Shintani-Smith S, Peters AT, Kato A, Stevens WS, Schleimer RP, Tan BK
Int Forum Allergy Rhinol 2022 Nov;12(11):1330-1339. Epub 2022 May 19 doi: 10.1002/alr.23005. PMID: 35362251Free PMC Article
Volumetric study of the maxillary sinus in patients with sinus pathology.
Pérez Sayáns M, Suárez Quintanilla JA, Chamorro Petronacci CM, Suárez Peñaranda JM, López Jornet P, Gómez García F, Guerrero Sánchez Y
PLoS One 2020;15(6):e0234915. Epub 2020 Jun 18 doi: 10.1371/journal.pone.0234915. PMID: 32555640Free PMC Article
Mucoceles of the frontal sinus. Clinical and therapeutical considerations.
Gavioli C, Grasso DL, Carinci F, Amoroso C, Pastore A
Minerva Stomatol 2002 Sep;51(9):385-90. PMID: 12473975

Recent systematic reviews

Efficacy of steroid-eluting stents in management of chronic rhinosinusitis after endoscopic sinus surgery: updated meta-analysis.
Goshtasbi K, Abouzari M, Abiri A, Yasaka T, Sahyouni R, Bitner B, Tajudeen BA, Kuan EC
Int Forum Allergy Rhinol 2019 Dec;9(12):1443-1450. Epub 2019 Sep 20 doi: 10.1002/alr.22443. PMID: 31539461Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...