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Polyp of frontal sinus

MedGen UID:
137927
•Concept ID:
C0339814
•
Neoplastic Process
Synonyms: Frontal sinus polyp; Frontal Sinus Polyp; frontal sinus polyp; Polyp of Frontal Sinus; polyp of frontal sinus; Polyp of the Frontal Sinus; polyp of the frontal sinus
SNOMED CT: Polyp of frontal sinus (195759002); Frontal sinus polyp (195759002)
 
Monarch Initiative: MONDO:0021408

Definition

A polyp that arises from the frontal sinus mucosa. It is characterized by the presence of edematous tissue infiltrated by inflammatory cells, including eosinophils. Causes include allergic rhinitis, chronic sinusitis, and cystic fibrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolyp of frontal sinus

Professional guidelines

PubMed

Clinical Consensus Statement: Balloon Dilation of the Sinuses.
Piccirillo JF, Payne SC, Rosenfeld RM, Baroody FM, Batra PS, DelGaudio JM, Edelstein DR, Lane AP, Luong AU, Manes RP, McCoul ED, Platt MP, Reh DD, Corrigan MD
Otolaryngol Head Neck Surg 2018 Feb;158(2):203-214. doi: 10.1177/0194599817750086. PMID: 29389303
Evaluation of a Minimally Disruptive Treatment Protocol for Frontal Sinus Fractures.
Patel SA, Berens AM, Devarajan K, Whipple ME, Moe KS
JAMA Facial Plast Surg 2017 May 1;19(3):225-231. doi: 10.1001/jamafacial.2016.1769. PMID: 28152148Free PMC Article
Recognition and management of sinusitis.
Evans KL
Drugs 1998 Jul;56(1):59-71. doi: 10.2165/00003495-199856010-00006. PMID: 9664199

Recent clinical studies

Etiology

Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
The role of frontal sinus drillouts in nasal polyposis.
Orgain CA, Harvey RJ
Curr Opin Otolaryngol Head Neck Surg 2018 Feb;26(1):34-40. doi: 10.1097/MOO.0000000000000425. PMID: 29095709
Chapter 8: Rhinosinusitis.
Georgy MS, Peters AT
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:24-27. doi: 10.2500/aap.2012.33.3538. PMID: 22794681
Mucoceles of the frontal sinus. Clinical and therapeutical considerations.
Gavioli C, Grasso DL, Carinci F, Amoroso C, Pastore A
Minerva Stomatol 2002 Sep;51(9):385-90. PMID: 12473975
Frontal sinus stents.
Freeman SB, Blom ED
Laryngoscope 2000 Jul;110(7):1179-82. doi: 10.1097/00005537-200007000-00021. PMID: 10892692

Diagnosis

Volumetric study of the maxillary sinus in patients with sinus pathology.
Pérez Sayáns M, Suárez Quintanilla JA, Chamorro Petronacci CM, Suárez Peñaranda JM, López Jornet P, Gómez García F, Guerrero Sánchez Y
PLoS One 2020;15(6):e0234915. Epub 2020 Jun 18 doi: 10.1371/journal.pone.0234915. PMID: 32555640Free PMC Article
Clinical Consensus Statement: Balloon Dilation of the Sinuses.
Piccirillo JF, Payne SC, Rosenfeld RM, Baroody FM, Batra PS, DelGaudio JM, Edelstein DR, Lane AP, Luong AU, Manes RP, McCoul ED, Platt MP, Reh DD, Corrigan MD
Otolaryngol Head Neck Surg 2018 Feb;158(2):203-214. doi: 10.1177/0194599817750086. PMID: 29389303
The role of frontal sinus drillouts in nasal polyposis.
Orgain CA, Harvey RJ
Curr Opin Otolaryngol Head Neck Surg 2018 Feb;26(1):34-40. doi: 10.1097/MOO.0000000000000425. PMID: 29095709
Chronic Rhinosinusitis in Patients with Cystic Fibrosis.
Hamilos DL
J Allergy Clin Immunol Pract 2016 Jul-Aug;4(4):605-12. doi: 10.1016/j.jaip.2016.04.013. PMID: 27393775
Chapter 8: Rhinosinusitis.
Georgy MS, Peters AT
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:24-27. doi: 10.2500/aap.2012.33.3538. PMID: 22794681

Therapy

Use of intraoperative frontal sinus mometasone-eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps.
Schneider AL, Racette SD, Kang AK, Reddy AT, Huang JH, Lehmann DS, Price CPE, Eide JG, Rodeghiero SR, Conley DB, Welch KC, Kern RC, Shintani-Smith S, Peters AT, Kato A, Stevens WS, Schleimer RP, Tan BK
Int Forum Allergy Rhinol 2022 Nov;12(11):1330-1339. Epub 2022 May 19 doi: 10.1002/alr.23005. PMID: 35362251Free PMC Article
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
Endoscopic Management of Chronic Frontal Sinusitis: Prospective Quality of Life Analysis.
Askar MH, Gamea A, Tomoum MO, Elsherif HS, Ebert C, Senior BA
Ann Otol Rhinol Laryngol 2015 Aug;124(8):638-48. Epub 2015 Mar 3 doi: 10.1177/0003489415573959. PMID: 25736024
Five 'nontraditional' techniques for use in patients with recalcitrant sinusitis.
Schneider JS, Archilla A, Duncavage JA
Curr Opin Otolaryngol Head Neck Surg 2013 Feb;21(1):39-44. doi: 10.1097/MOO.0b013e32835bf65b. PMID: 23262744
Frontal sinus irrigation: indications, results, and complications.
Klossek JM, Fontanel JP
Otolaryngol Clin North Am 2001 Feb;34(1):91-100. doi: 10.1016/s0030-6665(05)70297-8. PMID: 11344064

Prognosis

Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
The role of frontal sinus drillouts in nasal polyposis.
Orgain CA, Harvey RJ
Curr Opin Otolaryngol Head Neck Surg 2018 Feb;26(1):34-40. doi: 10.1097/MOO.0000000000000425. PMID: 29095709
Evaluation of a Minimally Disruptive Treatment Protocol for Frontal Sinus Fractures.
Patel SA, Berens AM, Devarajan K, Whipple ME, Moe KS
JAMA Facial Plast Surg 2017 May 1;19(3):225-231. doi: 10.1001/jamafacial.2016.1769. PMID: 28152148Free PMC Article
Mucoceles of the frontal sinus. Clinical and therapeutical considerations.
Gavioli C, Grasso DL, Carinci F, Amoroso C, Pastore A
Minerva Stomatol 2002 Sep;51(9):385-90. PMID: 12473975
Frontal sinus stents.
Freeman SB, Blom ED
Laryngoscope 2000 Jul;110(7):1179-82. doi: 10.1097/00005537-200007000-00021. PMID: 10892692

Clinical prediction guides

Use of intraoperative frontal sinus mometasone-eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps.
Schneider AL, Racette SD, Kang AK, Reddy AT, Huang JH, Lehmann DS, Price CPE, Eide JG, Rodeghiero SR, Conley DB, Welch KC, Kern RC, Shintani-Smith S, Peters AT, Kato A, Stevens WS, Schleimer RP, Tan BK
Int Forum Allergy Rhinol 2022 Nov;12(11):1330-1339. Epub 2022 May 19 doi: 10.1002/alr.23005. PMID: 35362251Free PMC Article
Volumetric study of the maxillary sinus in patients with sinus pathology.
Pérez Sayáns M, Suárez Quintanilla JA, Chamorro Petronacci CM, Suárez Peñaranda JM, López Jornet P, Gómez García F, Guerrero Sánchez Y
PLoS One 2020;15(6):e0234915. Epub 2020 Jun 18 doi: 10.1371/journal.pone.0234915. PMID: 32555640Free PMC Article
Impact of residual frontal recess cells on frontal sinusitis after endoscopic sinus surgery.
Nakayama T, Asaka D, Kuboki A, Okushi T, Kojima H
Eur Arch Otorhinolaryngol 2018 Jul;275(7):1795-1801. Epub 2018 May 18 doi: 10.1007/s00405-018-5003-7. PMID: 29777294
Role of frontal sinus surgery in nasal polyp recurrence.
Bassiouni A, Wormald PJ
Laryngoscope 2013 Jan;123(1):36-41. Epub 2012 Oct 15 doi: 10.1002/lary.23610. PMID: 23070897
Mucoceles of the frontal sinus. Clinical and therapeutical considerations.
Gavioli C, Grasso DL, Carinci F, Amoroso C, Pastore A
Minerva Stomatol 2002 Sep;51(9):385-90. PMID: 12473975

Recent systematic reviews

Efficacy of steroid-eluting stents in management of chronic rhinosinusitis after endoscopic sinus surgery: updated meta-analysis.
Goshtasbi K, Abouzari M, Abiri A, Yasaka T, Sahyouni R, Bitner B, Tajudeen BA, Kuan EC
Int Forum Allergy Rhinol 2019 Dec;9(12):1443-1450. Epub 2019 Sep 20 doi: 10.1002/alr.22443. PMID: 31539461Free PMC Article

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