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Bilateral alveolar cleft of maxilla

MedGen UID:
1379910
•Concept ID:
C4477071
•
Congenital Abnormality
HPO: HP:0410034

Definition

Nonmidline alveolar cleft of the maxilla. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBilateral alveolar cleft of maxilla

Professional guidelines

PubMed

Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735
Management of the premaxilla in the treatment of bilateral cleft of lip and palate: what can the literature tell us?
Bittermann GK, de Ruiter AP, Janssen NG, Bittermann AJ, van der Molen AM, van Es RJ, Rosenberg AJ, Koole R
Clin Oral Investig 2016 Mar;20(2):207-17. Epub 2015 Sep 16 doi: 10.1007/s00784-015-1589-y. PMID: 26374747Free PMC Article
Management of the prominent premaxilla in bilateral cleft lip and palate.
Aburezq H, Daskalogiannakis J, Forrest C
Cleft Palate Craniofac J 2006 Jan;43(1):92-5. doi: 10.1597/04-114r.1. PMID: 16405381

Recent clinical studies

Etiology

Cleft lip and palate cause large variations in size and location of the posterior superior alveolar canal.
de Gittins EVCD, Yaedú RYF, Lauris JRP, Rubira CMF, Pagin BSC, Rubira-Bullen IRF
Clin Oral Investig 2021 Jul;25(7):4451-4458. Epub 2021 Jan 8 doi: 10.1007/s00784-020-03757-9. PMID: 33417062
The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM).
Oliveira NV, Tou GAA, Silva RS, Rezende SE, Pretti H, Macari S
Braz Dent J 2020 Jan-Apr;31(2):190-196. doi: 10.1590/0103-6440202003040. PMID: 32556020
Incidence of complications in secondary alveolar bone grafting of bilateral clefts with premaxillary osteotomy: a retrospective cohort study.
Bittermann GKP, van Es RJJ, de Ruiter AP, Frank MH, Bittermann AJN, van der Molen ABM, Koole R, Rosenberg AJWP
Clin Oral Investig 2020 Feb;24(2):915-925. Epub 2019 Jun 26 doi: 10.1007/s00784-019-02977-y. PMID: 31250194
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381

Diagnosis

Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts.
Wilson AT, Wu RT, Sawh-Martinez R, Steinbacher DM
J Oral Maxillofac Surg 2019 Apr;77(4):850.e1-850.e5. Epub 2018 Nov 26 doi: 10.1016/j.joms.2018.11.011. PMID: 30576673
A Digital Assessment of the Maxillary Deformity Correction in Infants With Bilateral Cleft Lip and Palate Using Computer-Aided Nasoalveolar Molding.
Gong X, Zhao J, Zheng J, Yu Q
J Craniofac Surg 2017 Sep;28(6):1543-1548. doi: 10.1097/SCS.0000000000003812. PMID: 28708645
First-Trimester Sonographic Evaluation of Palatine Clefts: A Novel Diagnostic Approach.
Lakshmy SR, Deepa S, Rose N, Mookan S, Agnees J
J Ultrasound Med 2017 Jul;36(7):1397-1414. Epub 2017 Apr 18 doi: 10.7863/ultra.16.05084. PMID: 28417474
Premaxillary Repositioning in the Severe Form of Bilateral Cleft Lip and Palate.
Koh KS, Han WY, Jeong WS, Oh TS, Kwon SM, Choi JW
J Craniofac Surg 2016 Sep;27(6):1440-4. doi: 10.1097/SCS.0000000000002729. PMID: 27300460
Treatment algorithm for bilateral alveolar cleft based on the position of the premaxilla and the width of the alveolar gap.
Koh KS, Kim H, Oh TS, Kwon SM, Choi JW
J Plast Reconstr Aesthet Surg 2013 Sep;66(9):1212-8. Epub 2013 May 21 doi: 10.1016/j.bjps.2013.04.060. PMID: 23702194

Therapy

Polyphosphate (PolyP) for alveolar cleft repair: study protocol for a pilot randomized controlled trial.
Alkaabi SA, Natsir Kalla DS, Alsabri GA, Fauzi A, Tajrin A, Müller WEG, Schröder HC, Wang XG, Forouzanfar T, Helder MN, Ruslin M
Trials 2021 Jun 14;22(1):393. doi: 10.1186/s13063-021-05325-2. PMID: 34127045Free PMC Article
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381
Interdisciplinary treatment of an adult with complete bilateral cleft lip and palate.
Okada W, Fukui T, Saito T, Ohkubo C, Hamada Y, Nakamura Y
Am J Orthod Dentofacial Orthop 2012 Apr;141(4 Suppl):S149-58. doi: 10.1016/j.ajodo.2011.07.025. PMID: 22449595
Nonunion of the external maxillary distraction in cleft lip and palate: analysis of possible reasons.
He D, Genecov DG, Barcelo R
J Oral Maxillofac Surg 2010 Oct;68(10):2402-11. doi: 10.1016/j.joms.2009.09.018. PMID: 20605305
Maxillary alveolar cleft repair in dogs using recombinant human bone morphogenetic protein-2 and a polymer carrier.
Mayer M, Hollinger J, Ron E, Wozney J
Plast Reconstr Surg 1996 Aug;98(2):247-59. doi: 10.1097/00006534-199608000-00006. PMID: 8764712

Prognosis

The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM).
Oliveira NV, Tou GAA, Silva RS, Rezende SE, Pretti H, Macari S
Braz Dent J 2020 Jan-Apr;31(2):190-196. doi: 10.1590/0103-6440202003040. PMID: 32556020
Incidence of complications in secondary alveolar bone grafting of bilateral clefts with premaxillary osteotomy: a retrospective cohort study.
Bittermann GKP, van Es RJJ, de Ruiter AP, Frank MH, Bittermann AJN, van der Molen ABM, Koole R, Rosenberg AJWP
Clin Oral Investig 2020 Feb;24(2):915-925. Epub 2019 Jun 26 doi: 10.1007/s00784-019-02977-y. PMID: 31250194
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562
Primary Premaxillary Setback and Repair of Bilateral Complete Cleft Lip: Indications, Technique, and Outcomes.
Vyas RM, Kim DC, Padwa BL, Mulliken JB
Cleft Palate Craniofac J 2016 May;53(3):302-8. Epub 2015 Nov 17 doi: 10.1597/14-099. PMID: 26575966
Management of the prominent premaxilla in bilateral cleft lip and palate.
Aburezq H, Daskalogiannakis J, Forrest C
Cleft Palate Craniofac J 2006 Jan;43(1):92-5. doi: 10.1597/04-114r.1. PMID: 16405381

Clinical prediction guides

Retrospective analysis of clinical outcomes in bilateral cleft lip and palate patients after secondary alveolar bone grafting and premaxilla osteotomy, using a new dento-maxillary scoring system.
Bittermann GKP, van Es RJJ, de Ruiter AP, Bittermann AJN, Koole R, Rosenberg AJWP
J Craniomaxillofac Surg 2021 Feb;49(2):110-117. Epub 2020 Dec 15 doi: 10.1016/j.jcms.2020.12.006. PMID: 33357967
The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM).
Oliveira NV, Tou GAA, Silva RS, Rezende SE, Pretti H, Macari S
Braz Dent J 2020 Jan-Apr;31(2):190-196. doi: 10.1590/0103-6440202003040. PMID: 32556020
Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts.
Wilson AT, Wu RT, Sawh-Martinez R, Steinbacher DM
J Oral Maxillofac Surg 2019 Apr;77(4):850.e1-850.e5. Epub 2018 Nov 26 doi: 10.1016/j.joms.2018.11.011. PMID: 30576673
Premaxillary Repositioning in the Severe Form of Bilateral Cleft Lip and Palate.
Koh KS, Han WY, Jeong WS, Oh TS, Kwon SM, Choi JW
J Craniofac Surg 2016 Sep;27(6):1440-4. doi: 10.1097/SCS.0000000000002729. PMID: 27300460
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381

Recent systematic reviews

Effects of labial adhesion on maxillary arch dimensions and nasolabial esthetics in cleft lip and palate: a systematic review.
Thierens L, Brusselaers N, De Roo N, De Pauw G
Oral Dis 2017 Oct;23(7):889-896. Epub 2017 Jan 24 doi: 10.1111/odi.12613. PMID: 27878905

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