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Abnormal circulating B-type natriuretic peptide concentration

MedGen UID:
1389340
•Concept ID:
C4476997
•
Finding
Synonym: Abnormal B-type natriuretic peptide concentration
 
HPO: HP:0031138

Definition

A deviation from the normal circulating concentration of B-type natriuretic peptide (BNP). [from HPO]

Professional guidelines

PubMed

Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.
Merz WM, Kübler K, Fimmers R, Stoffel-Wagner B, Geipel A, Gembruch U
Pediatr Res 2012 Aug;72(2):174-8. doi: 10.1038/pr.2012.53. PMID: 22546865
Prevalence and prognostic significance of heart failure stages: application of the American College of Cardiology/American Heart Association heart failure staging criteria in the community.
Ammar KA, Jacobsen SJ, Mahoney DW, Kors JA, Redfield MM, Burnett JC Jr, Rodeheffer RJ
Circulation 2007 Mar 27;115(12):1563-70. Epub 2007 Mar 12 doi: 10.1161/CIRCULATIONAHA.106.666818. PMID: 17353436

Recent clinical studies

Etiology

B-type natriuretic peptide in low-risk pregnancy and pregnancy with congenital heart disease.
Dos Santos F, Dennehy N, Steer PJ, Johnson MR
Int J Gynaecol Obstet 2023 Oct;163(1):218-225. Epub 2023 Apr 26 doi: 10.1002/ijgo.14807. PMID: 37185795
Systemic-to-Pulmonary Collateral Flow Correlates with Clinical Condition Late After the Fontan Procedure.
Kodama Y, Ishikawa Y, Kuraoka A, Nakamura M, Oda S, Nakano T, Kado H, Sakamoto I, Ohtani K, Ide T, Tsutsui H, Sagawa K
Pediatr Cardiol 2020 Dec;41(8):1800-1806. Epub 2020 Sep 11 doi: 10.1007/s00246-020-02450-8. PMID: 32915292
Correlations between electrocardiogram and biomarkers in acute pulmonary embolism: Analysis of ZATPOL-2 Registry.
Kukla P, Kosior DA, Tomaszewski A, Ptaszyńska-Kopczyńska K, Widejko K, Długopolski R, Skrzyński A, Błaszczak P, Fijorek K, Kurzyna M
Ann Noninvasive Electrocardiol 2017 Jul;22(4) Epub 2017 Feb 18 doi: 10.1111/anec.12439. PMID: 28213932Free PMC Article
Association between serum adipocyte fatty-acid binding protein concentrations, left ventricular function and myocardial perfusion abnormalities in patients with coronary artery disease.
Huang CL, Wu YW, Wu CC, Lin L, Wu YC, Hsu PY, Jong YS, Yang WS
Cardiovasc Diabetol 2013 Jul 17;12:105. doi: 10.1186/1475-2840-12-105. PMID: 23866022Free PMC Article
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, Badesch DB, McGoon MD, McLaughlin VV, Roecker EB, Gerber MJ, Dufton C, Wiens BL, Rubin LJ; Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group
Circulation 2008 Jun 10;117(23):3010-9. Epub 2008 May 27 doi: 10.1161/CIRCULATIONAHA.107.742510. PMID: 18506008

Diagnosis

Correlations between electrocardiogram and biomarkers in acute pulmonary embolism: Analysis of ZATPOL-2 Registry.
Kukla P, Kosior DA, Tomaszewski A, Ptaszyńska-Kopczyńska K, Widejko K, Długopolski R, Skrzyński A, Błaszczak P, Fijorek K, Kurzyna M
Ann Noninvasive Electrocardiol 2017 Jul;22(4) Epub 2017 Feb 18 doi: 10.1111/anec.12439. PMID: 28213932Free PMC Article
Association between serum adipocyte fatty-acid binding protein concentrations, left ventricular function and myocardial perfusion abnormalities in patients with coronary artery disease.
Huang CL, Wu YW, Wu CC, Lin L, Wu YC, Hsu PY, Jong YS, Yang WS
Cardiovasc Diabetol 2013 Jul 17;12:105. doi: 10.1186/1475-2840-12-105. PMID: 23866022Free PMC Article
Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.
Merz WM, Kübler K, Fimmers R, Stoffel-Wagner B, Geipel A, Gembruch U
Pediatr Res 2012 Aug;72(2):174-8. doi: 10.1038/pr.2012.53. PMID: 22546865
Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance.
Abassi Z, Karram T, Ellaham S, Winaver J, Hoffman A
Pharmacol Ther 2004 Jun;102(3):223-41. doi: 10.1016/j.pharmthera.2004.04.004. PMID: 15246247
B-type natriuretic peptide in cardiovascular disease.
de Lemos JA, McGuire DK, Drazner MH
Lancet 2003 Jul 26;362(9380):316-22. doi: 10.1016/S0140-6736(03)13976-1. PMID: 12892964

Therapy

Electrocardiographic Left Atrial Abnormality and B-Type Natriuretic Peptide in a General Japanese Population: NIPPON DATA2010.
Shoji S, Kohsaka S, Sawano M, Okamura T, Hirata A, Sugiyama D, Ohkubo T, Nakamura Y, Watanabe M, Kadota A, Ueshima H, Okayama A, Miura K; NIPPON DATA2010 Research Group
J Atheroscler Thromb 2021 Jan 1;28(1):34-43. Epub 2020 Mar 19 doi: 10.5551/jat.54171. PMID: 32188793Free PMC Article
Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic Shock.
Masson S, Caironi P, Fanizza C, Carrer S, Caricato A, Fassini P, Vago T, Romero M, Tognoni G, Gattinoni L, Latini R; Albumin Italian Outcome Sepsis Study Investigators
Crit Care Med 2016 Apr;44(4):707-16. doi: 10.1097/CCM.0000000000001473. PMID: 26571184
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, Badesch DB, McGoon MD, McLaughlin VV, Roecker EB, Gerber MJ, Dufton C, Wiens BL, Rubin LJ; Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group
Circulation 2008 Jun 10;117(23):3010-9. Epub 2008 May 27 doi: 10.1161/CIRCULATIONAHA.107.742510. PMID: 18506008
Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance.
Abassi Z, Karram T, Ellaham S, Winaver J, Hoffman A
Pharmacol Ther 2004 Jun;102(3):223-41. doi: 10.1016/j.pharmthera.2004.04.004. PMID: 15246247
B-type natriuretic peptide in cardiovascular disease.
de Lemos JA, McGuire DK, Drazner MH
Lancet 2003 Jul 26;362(9380):316-22. doi: 10.1016/S0140-6736(03)13976-1. PMID: 12892964

Prognosis

Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP.
Palm J, Ono M, Niedermaier C, Hörer J, Hoffmann G, Holdenrieder S, Klawonn F, Ewert P
Int J Cardiol 2024 Jul 1;406:131983. Epub 2024 Mar 22 doi: 10.1016/j.ijcard.2024.131983. PMID: 38521506
Correlations between electrocardiogram and biomarkers in acute pulmonary embolism: Analysis of ZATPOL-2 Registry.
Kukla P, Kosior DA, Tomaszewski A, Ptaszyńska-Kopczyńska K, Widejko K, Długopolski R, Skrzyński A, Błaszczak P, Fijorek K, Kurzyna M
Ann Noninvasive Electrocardiol 2017 Jul;22(4) Epub 2017 Feb 18 doi: 10.1111/anec.12439. PMID: 28213932Free PMC Article
Association between serum adipocyte fatty-acid binding protein concentrations, left ventricular function and myocardial perfusion abnormalities in patients with coronary artery disease.
Huang CL, Wu YW, Wu CC, Lin L, Wu YC, Hsu PY, Jong YS, Yang WS
Cardiovasc Diabetol 2013 Jul 17;12:105. doi: 10.1186/1475-2840-12-105. PMID: 23866022Free PMC Article
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, Badesch DB, McGoon MD, McLaughlin VV, Roecker EB, Gerber MJ, Dufton C, Wiens BL, Rubin LJ; Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group
Circulation 2008 Jun 10;117(23):3010-9. Epub 2008 May 27 doi: 10.1161/CIRCULATIONAHA.107.742510. PMID: 18506008
B-type natriuretic peptide in cardiovascular disease.
de Lemos JA, McGuire DK, Drazner MH
Lancet 2003 Jul 26;362(9380):316-22. doi: 10.1016/S0140-6736(03)13976-1. PMID: 12892964

Clinical prediction guides

Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP.
Palm J, Ono M, Niedermaier C, Hörer J, Hoffmann G, Holdenrieder S, Klawonn F, Ewert P
Int J Cardiol 2024 Jul 1;406:131983. Epub 2024 Mar 22 doi: 10.1016/j.ijcard.2024.131983. PMID: 38521506
Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP.
Palm J, Holdenrieder S, Hoffmann G, Hörer J, Shi R, Klawonn F, Ewert P
J Am Coll Cardiol 2021 Nov 9;78(19):1890-1900. doi: 10.1016/j.jacc.2021.08.056. PMID: 34736565
Correlations between electrocardiogram and biomarkers in acute pulmonary embolism: Analysis of ZATPOL-2 Registry.
Kukla P, Kosior DA, Tomaszewski A, Ptaszyńska-Kopczyńska K, Widejko K, Długopolski R, Skrzyński A, Błaszczak P, Fijorek K, Kurzyna M
Ann Noninvasive Electrocardiol 2017 Jul;22(4) Epub 2017 Feb 18 doi: 10.1111/anec.12439. PMID: 28213932Free PMC Article
Association between serum adipocyte fatty-acid binding protein concentrations, left ventricular function and myocardial perfusion abnormalities in patients with coronary artery disease.
Huang CL, Wu YW, Wu CC, Lin L, Wu YC, Hsu PY, Jong YS, Yang WS
Cardiovasc Diabetol 2013 Jul 17;12:105. doi: 10.1186/1475-2840-12-105. PMID: 23866022Free PMC Article
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, Badesch DB, McGoon MD, McLaughlin VV, Roecker EB, Gerber MJ, Dufton C, Wiens BL, Rubin LJ; Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group
Circulation 2008 Jun 10;117(23):3010-9. Epub 2008 May 27 doi: 10.1161/CIRCULATIONAHA.107.742510. PMID: 18506008

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