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Abnormal circulating B-type natriuretic peptide concentration

MedGen UID:
1389340
•Concept ID:
C4476997
•
Finding
Synonym: Abnormal B-type natriuretic peptide concentration
 
HPO: HP:0031138

Definition

A deviation from the normal circulating concentration of B-type natriuretic peptide (BNP). [from HPO]

Professional guidelines

PubMed

Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.
Merz WM, Kübler K, Fimmers R, Stoffel-Wagner B, Geipel A, Gembruch U
Pediatr Res 2012 Aug;72(2):174-8. doi: 10.1038/pr.2012.53. PMID: 22546865
Prevalence and prognostic significance of heart failure stages: application of the American College of Cardiology/American Heart Association heart failure staging criteria in the community.
Ammar KA, Jacobsen SJ, Mahoney DW, Kors JA, Redfield MM, Burnett JC Jr, Rodeheffer RJ
Circulation 2007 Mar 27;115(12):1563-70. Epub 2007 Mar 12 doi: 10.1161/CIRCULATIONAHA.106.666818. PMID: 17353436

Recent clinical studies

Etiology

B-type natriuretic peptide in low-risk pregnancy and pregnancy with congenital heart disease.
Dos Santos F, Dennehy N, Steer PJ, Johnson MR
Int J Gynaecol Obstet 2023 Oct;163(1):218-225. Epub 2023 Apr 26 doi: 10.1002/ijgo.14807. PMID: 37185795
Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP.
Palm J, Holdenrieder S, Hoffmann G, Hörer J, Shi R, Klawonn F, Ewert P
J Am Coll Cardiol 2021 Nov 9;78(19):1890-1900. doi: 10.1016/j.jacc.2021.08.056. PMID: 34736565
Electrocardiographic Left Atrial Abnormality and B-Type Natriuretic Peptide in a General Japanese Population: NIPPON DATA2010.
Shoji S, Kohsaka S, Sawano M, Okamura T, Hirata A, Sugiyama D, Ohkubo T, Nakamura Y, Watanabe M, Kadota A, Ueshima H, Okayama A, Miura K; NIPPON DATA2010 Research Group
J Atheroscler Thromb 2021 Jan 1;28(1):34-43. Epub 2020 Mar 19 doi: 10.5551/jat.54171. PMID: 32188793Free PMC Article
Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta.
Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA
Congenit Heart Dis 2019 May;14(3):446-453. Epub 2019 Jan 16 doi: 10.1111/chd.12744. PMID: 30650250Free PMC Article
Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.
Merz WM, Kübler K, Fimmers R, Stoffel-Wagner B, Geipel A, Gembruch U
Pediatr Res 2012 Aug;72(2):174-8. doi: 10.1038/pr.2012.53. PMID: 22546865

Diagnosis

Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP.
Palm J, Holdenrieder S, Hoffmann G, Hörer J, Shi R, Klawonn F, Ewert P
J Am Coll Cardiol 2021 Nov 9;78(19):1890-1900. doi: 10.1016/j.jacc.2021.08.056. PMID: 34736565
Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic Shock.
Masson S, Caironi P, Fanizza C, Carrer S, Caricato A, Fassini P, Vago T, Romero M, Tognoni G, Gattinoni L, Latini R; Albumin Italian Outcome Sepsis Study Investigators
Crit Care Med 2016 Apr;44(4):707-16. doi: 10.1097/CCM.0000000000001473. PMID: 26571184
Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.
Merz WM, Kübler K, Fimmers R, Stoffel-Wagner B, Geipel A, Gembruch U
Pediatr Res 2012 Aug;72(2):174-8. doi: 10.1038/pr.2012.53. PMID: 22546865
Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance.
Abassi Z, Karram T, Ellaham S, Winaver J, Hoffman A
Pharmacol Ther 2004 Jun;102(3):223-41. doi: 10.1016/j.pharmthera.2004.04.004. PMID: 15246247
B-type natriuretic peptide in cardiovascular disease.
de Lemos JA, McGuire DK, Drazner MH
Lancet 2003 Jul 26;362(9380):316-22. doi: 10.1016/S0140-6736(03)13976-1. PMID: 12892964

Therapy

Electrocardiographic Left Atrial Abnormality and B-Type Natriuretic Peptide in a General Japanese Population: NIPPON DATA2010.
Shoji S, Kohsaka S, Sawano M, Okamura T, Hirata A, Sugiyama D, Ohkubo T, Nakamura Y, Watanabe M, Kadota A, Ueshima H, Okayama A, Miura K; NIPPON DATA2010 Research Group
J Atheroscler Thromb 2021 Jan 1;28(1):34-43. Epub 2020 Mar 19 doi: 10.5551/jat.54171. PMID: 32188793Free PMC Article
Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta.
Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA
Congenit Heart Dis 2019 May;14(3):446-453. Epub 2019 Jan 16 doi: 10.1111/chd.12744. PMID: 30650250Free PMC Article
Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic Shock.
Masson S, Caironi P, Fanizza C, Carrer S, Caricato A, Fassini P, Vago T, Romero M, Tognoni G, Gattinoni L, Latini R; Albumin Italian Outcome Sepsis Study Investigators
Crit Care Med 2016 Apr;44(4):707-16. doi: 10.1097/CCM.0000000000001473. PMID: 26571184
Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance.
Abassi Z, Karram T, Ellaham S, Winaver J, Hoffman A
Pharmacol Ther 2004 Jun;102(3):223-41. doi: 10.1016/j.pharmthera.2004.04.004. PMID: 15246247
B-type natriuretic peptide in cardiovascular disease.
de Lemos JA, McGuire DK, Drazner MH
Lancet 2003 Jul 26;362(9380):316-22. doi: 10.1016/S0140-6736(03)13976-1. PMID: 12892964

Prognosis

Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP.
Palm J, Holdenrieder S, Hoffmann G, Hörer J, Shi R, Klawonn F, Ewert P
J Am Coll Cardiol 2021 Nov 9;78(19):1890-1900. doi: 10.1016/j.jacc.2021.08.056. PMID: 34736565
Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta.
Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA
Congenit Heart Dis 2019 May;14(3):446-453. Epub 2019 Jan 16 doi: 10.1111/chd.12744. PMID: 30650250Free PMC Article
Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic Shock.
Masson S, Caironi P, Fanizza C, Carrer S, Caricato A, Fassini P, Vago T, Romero M, Tognoni G, Gattinoni L, Latini R; Albumin Italian Outcome Sepsis Study Investigators
Crit Care Med 2016 Apr;44(4):707-16. doi: 10.1097/CCM.0000000000001473. PMID: 26571184
Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance.
Abassi Z, Karram T, Ellaham S, Winaver J, Hoffman A
Pharmacol Ther 2004 Jun;102(3):223-41. doi: 10.1016/j.pharmthera.2004.04.004. PMID: 15246247
B-type natriuretic peptide in cardiovascular disease.
de Lemos JA, McGuire DK, Drazner MH
Lancet 2003 Jul 26;362(9380):316-22. doi: 10.1016/S0140-6736(03)13976-1. PMID: 12892964

Clinical prediction guides

Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP.
Palm J, Holdenrieder S, Hoffmann G, Hörer J, Shi R, Klawonn F, Ewert P
J Am Coll Cardiol 2021 Nov 9;78(19):1890-1900. doi: 10.1016/j.jacc.2021.08.056. PMID: 34736565
Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta.
Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA
Congenit Heart Dis 2019 May;14(3):446-453. Epub 2019 Jan 16 doi: 10.1111/chd.12744. PMID: 30650250Free PMC Article
Clinical and Echocardiographic Characteristics and Cardiovascular Outcomes According to Diabetes Status in Patients With Heart Failure and Preserved Ejection Fraction: A Report From the I-Preserve Trial (Irbesartan in Heart Failure With Preserved Ejection Fraction).
Kristensen SL, Mogensen UM, Jhund PS, Petrie MC, Preiss D, Win S, Køber L, McKelvie RS, Zile MR, Anand IS, Komajda M, Gottdiener JS, Carson PE, McMurray JJ
Circulation 2017 Feb 21;135(8):724-735. Epub 2017 Jan 4 doi: 10.1161/CIRCULATIONAHA.116.024593. PMID: 28052977
Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic Shock.
Masson S, Caironi P, Fanizza C, Carrer S, Caricato A, Fassini P, Vago T, Romero M, Tognoni G, Gattinoni L, Latini R; Albumin Italian Outcome Sepsis Study Investigators
Crit Care Med 2016 Apr;44(4):707-16. doi: 10.1097/CCM.0000000000001473. PMID: 26571184
Cardiac hemodynamic profiles and pro-B-type natriuretic Peptide in cirrhotic patients undergoing liver transplantation.
Bernal V, Pascual I, Esquivias P, García-Gil A, Fernández C, Mateo JM, González M, Simón MA
Transplant Proc 2009 Apr;41(3):985-6. doi: 10.1016/j.transproceed.2009.02.020. PMID: 19376404

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