U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Whole-immunoglobulin paraproteinemia

MedGen UID:
1391402
•Concept ID:
C4476931
•
Finding
HPO: HP:0031050

Definition

An abnormal immunoglobulin (heavy and light chain) in the circulation and typically produced by a clonal population of B-cell derived plasma cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWhole-immunoglobulin paraproteinemia

Recent clinical studies

Diagnosis

A study of the interactions of an immunoglobulin light chain with artificial and B-lymphocyte membranes.
Wall JS, Ayoub FM, O'Shea PS
Front Biosci 1996 Aug 1;1:a46-58. doi: 10.2741/a105. PMID: 9159194

Therapy

Monoclonal immunoglobulin deposition disease associated with membranous features.
Komatsuda A, Masai R, Ohtani H, Togashi M, Maki N, Sawada K, Wakui H
Nephrol Dial Transplant 2008 Dec;23(12):3888-94. Epub 2008 Jul 2 doi: 10.1093/ndt/gfn363. PMID: 18596130
Serum-free light chain analysis by crossed immunoelectrophoresis: correlation with plasmapheresis in light chain disease nephropathy.
McLeod BC, Viernes AL, Sassetti RJ
Am J Hematol 1983 Aug;15(1):75-88. doi: 10.1002/ajh.2830150109. PMID: 6410911

Prognosis

Monoclonal immunoglobulin deposition disease associated with membranous features.
Komatsuda A, Masai R, Ohtani H, Togashi M, Maki N, Sawada K, Wakui H
Nephrol Dial Transplant 2008 Dec;23(12):3888-94. Epub 2008 Jul 2 doi: 10.1093/ndt/gfn363. PMID: 18596130
Serum-free light chain analysis by crossed immunoelectrophoresis: correlation with plasmapheresis in light chain disease nephropathy.
McLeod BC, Viernes AL, Sassetti RJ
Am J Hematol 1983 Aug;15(1):75-88. doi: 10.1002/ajh.2830150109. PMID: 6410911

Clinical prediction guides

Monoclonal immunoglobulin deposition disease associated with membranous features.
Komatsuda A, Masai R, Ohtani H, Togashi M, Maki N, Sawada K, Wakui H
Nephrol Dial Transplant 2008 Dec;23(12):3888-94. Epub 2008 Jul 2 doi: 10.1093/ndt/gfn363. PMID: 18596130
'Mu' heavy chain type 'non-excretory' myeloma.
Guglielmo P, Granata P, Di Raimondo F, Lombardo T, Giustolisi R, Cacciola E
Scand J Haematol 1982 Jul;29(1):36-40. PMID: 6812210

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...