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Alcohol intoxication

MedGen UID:
1399
•Concept ID:
C0001969
•
Mental or Behavioral Dysfunction
Synonyms: Alcoholic Intoxication; Drunkenness; Drunkennesses; Intoxication, Alcoholic
SNOMED CT: Alcohol intoxication (25702006); Drunkenness (25702006); Drunk (25702006)

Definition

Disturbances in psychophysiological functions and responses as a result of consumption of a beverage containing ethanol. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlcohol intoxication

Professional guidelines

PubMed

Identification and management of acute alcohol intoxication.
Mirijello A, Sestito L, Antonelli M, Gasbarrini A, Addolorato G
Eur J Intern Med 2023 Feb;108:1-8. Epub 2022 Aug 16 doi: 10.1016/j.ejim.2022.08.013. PMID: 35985955
Role of first aid in the management of acute alcohol intoxication: a narrative review.
Piccioni A, Tarli C, Cardone S, Brigida M, D'Addio S, Covino M, Zanza C, Merra G, Ojetti V, Gasbarrini A, Addolorato G, Franceschi F
Eur Rev Med Pharmacol Sci 2020 Sep;24(17):9121-9128. doi: 10.26355/eurrev_202009_22859. PMID: 32965003
Alcohol: intoxication and poisoning - diagnosis and treatment.
Jung YC, Namkoong K
Handb Clin Neurol 2014;125:115-21. doi: 10.1016/B978-0-444-62619-6.00007-0. PMID: 25307571

Recent clinical studies

Etiology

Acute Alcohol Intoxication in Pediatric Emergencies.
Castro-Rodríguez C, Lorente-Romero J, Rivas-García A, García-Loygorri CF, Vázquez-López P, Marañón R
Pediatr Emerg Care 2022 Sep 1;38(9):e1523-e1528. Epub 2022 Jul 24 doi: 10.1097/PEC.0000000000002808. PMID: 35876736
Do not drink and lyse: alcohol intoxication increases fibrinolysis shutdown in injured patients.
Stettler GR, Moore EE, Nunns GR, Moore HB, Huebner BR, Silliman CC, Banerjee A, Sauaia A
Eur J Trauma Emerg Surg 2021 Dec;47(6):1827-1835. Epub 2020 Mar 10 doi: 10.1007/s00068-020-01328-x. PMID: 32157340Free PMC Article
Role of first aid in the management of acute alcohol intoxication: a narrative review.
Piccioni A, Tarli C, Cardone S, Brigida M, D'Addio S, Covino M, Zanza C, Merra G, Ojetti V, Gasbarrini A, Addolorato G, Franceschi F
Eur Rev Med Pharmacol Sci 2020 Sep;24(17):9121-9128. doi: 10.26355/eurrev_202009_22859. PMID: 32965003
Alcoholic metabolic emergencies.
Allison MG, McCurdy MT
Emerg Med Clin North Am 2014 May;32(2):293-301. Epub 2014 Feb 19 doi: 10.1016/j.emc.2013.12.002. PMID: 24766933
Acute alcohol intoxication.
Vonghia L, Leggio L, Ferrulli A, Bertini M, Gasbarrini G, Addolorato G; Alcoholism Treatment Study Group
Eur J Intern Med 2008 Dec;19(8):561-7. Epub 2008 Apr 2 doi: 10.1016/j.ejim.2007.06.033. PMID: 19046719

Diagnosis

Identification and management of acute alcohol intoxication.
Mirijello A, Sestito L, Antonelli M, Gasbarrini A, Addolorato G
Eur J Intern Med 2023 Feb;108:1-8. Epub 2022 Aug 16 doi: 10.1016/j.ejim.2022.08.013. PMID: 35985955
Acute alcohol intoxication: a clinical overview.
D'Angelo A, Petrella C, Greco A, Ralli M, Vitali M, Giovagnoli R, De Persis S, Fiore M, Ceccanti M, Messina MP
Clin Ter 2022 May 25;173(3):280-291. doi: 10.7417/CT.2022.2432. PMID: 35612344
Alcohol: intoxication and poisoning - diagnosis and treatment.
Jung YC, Namkoong K
Handb Clin Neurol 2014;125:115-21. doi: 10.1016/B978-0-444-62619-6.00007-0. PMID: 25307571
Recommendation for a definition of acute symptomatic seizure.
Beghi E, Carpio A, Forsgren L, Hesdorffer DC, Malmgren K, Sander JW, Tomson T, Hauser WA
Epilepsia 2010 Apr;51(4):671-5. Epub 2009 Sep 3 doi: 10.1111/j.1528-1167.2009.02285.x. PMID: 19732133
Acute alcohol intoxication.
Vonghia L, Leggio L, Ferrulli A, Bertini M, Gasbarrini G, Addolorato G; Alcoholism Treatment Study Group
Eur J Intern Med 2008 Dec;19(8):561-7. Epub 2008 Apr 2 doi: 10.1016/j.ejim.2007.06.033. PMID: 19046719

Therapy

Alcohol and disgust: An intimate relationship.
Stafford LD, Sekulla A, Morrison E, Fleischman DS, Harvey AJ
Drug Alcohol Depend 2020 Jan 1;206:107780. Epub 2019 Nov 26 doi: 10.1016/j.drugalcdep.2019.107780. PMID: 31835186
Alcohol: intoxication and poisoning - diagnosis and treatment.
Jung YC, Namkoong K
Handb Clin Neurol 2014;125:115-21. doi: 10.1016/B978-0-444-62619-6.00007-0. PMID: 25307571
Therapeutic roles of curcumin: lessons learned from clinical trials.
Gupta SC, Patchva S, Aggarwal BB
AAPS J 2013 Jan;15(1):195-218. Epub 2012 Nov 10 doi: 10.1208/s12248-012-9432-8. PMID: 23143785Free PMC Article
Acute alcohol intoxication.
Vonghia L, Leggio L, Ferrulli A, Bertini M, Gasbarrini G, Addolorato G; Alcoholism Treatment Study Group
Eur J Intern Med 2008 Dec;19(8):561-7. Epub 2008 Apr 2 doi: 10.1016/j.ejim.2007.06.033. PMID: 19046719
Alcoholism.
Bohn MJ
Psychiatr Clin North Am 1993 Dec;16(4):679-92. PMID: 8309806

Prognosis

Alcohol Consumption and 15 Causes of Fatal Injuries: A Systematic Review and Meta-Analysis.
Alpert HR, Slater ME, Yoon YH, Chen CM, Winstanley N, Esser MB
Am J Prev Med 2022 Aug;63(2):286-300. Epub 2022 May 15 doi: 10.1016/j.amepre.2022.03.025. PMID: 35581102Free PMC Article
Role of first aid in the management of acute alcohol intoxication: a narrative review.
Piccioni A, Tarli C, Cardone S, Brigida M, D'Addio S, Covino M, Zanza C, Merra G, Ojetti V, Gasbarrini A, Addolorato G, Franceschi F
Eur Rev Med Pharmacol Sci 2020 Sep;24(17):9121-9128. doi: 10.26355/eurrev_202009_22859. PMID: 32965003
Alcohol Use Disorder and Traumatic Brain Injury.
Weil ZM, Corrigan JD, Karelina K
Alcohol Res 2018;39(2):171-180. PMID: 31198656Free PMC Article
Alcoholic metabolic emergencies.
Allison MG, McCurdy MT
Emerg Med Clin North Am 2014 May;32(2):293-301. Epub 2014 Feb 19 doi: 10.1016/j.emc.2013.12.002. PMID: 24766933
Alcoholism.
Bohn MJ
Psychiatr Clin North Am 1993 Dec;16(4):679-92. PMID: 8309806

Clinical prediction guides

Acute Alcohol Intoxication in Pediatric Emergencies.
Castro-Rodríguez C, Lorente-Romero J, Rivas-García A, García-Loygorri CF, Vázquez-López P, Marañón R
Pediatr Emerg Care 2022 Sep 1;38(9):e1523-e1528. Epub 2022 Jul 24 doi: 10.1097/PEC.0000000000002808. PMID: 35876736
Time perception and alcohol use: A systematic review.
Nuyens FM, Billieux J, Maurage P
Neurosci Biobehav Rev 2021 Aug;127:377-403. Epub 2021 Apr 29 doi: 10.1016/j.neubiorev.2021.04.027. PMID: 33933506
Gender Differences in the Prediction of Alcohol Intoxication among Adolescents.
Jovičić Burić D, Muslić L, Krašić S, Markelić M, Pejnović Franelić I, Musić Milanović S
Subst Use Misuse 2021;56(7):1024-1034. Epub 2021 Apr 1 doi: 10.1080/10826084.2021.1906278. PMID: 33792493
Role of first aid in the management of acute alcohol intoxication: a narrative review.
Piccioni A, Tarli C, Cardone S, Brigida M, D'Addio S, Covino M, Zanza C, Merra G, Ojetti V, Gasbarrini A, Addolorato G, Franceschi F
Eur Rev Med Pharmacol Sci 2020 Sep;24(17):9121-9128. doi: 10.26355/eurrev_202009_22859. PMID: 32965003
Dexmedetomidine for Alcohol Withdrawal Syndrome.
Linn DD, Loeser KC
Ann Pharmacother 2015 Dec;49(12):1336-42. Epub 2015 Sep 23 doi: 10.1177/1060028015607038. PMID: 26400008

Recent systematic reviews

Adjunctive Dexmedetomidine in Alcohol Withdrawal Syndrome: A Systematic Review and Meta-analysis of Retrospective Cohort Studies and Randomized Controlled Trials.
Polintan ETT, Danganan LML, Cruz NS, Macapagal SC, Catahay JA, Patarroyo-Aponte G, Azmaiparashvili Z, Lo KB
Ann Pharmacother 2023 Jun;57(6):696-705. Epub 2022 Oct 18 doi: 10.1177/10600280221130458. PMID: 36258676
Alcohol Consumption and 15 Causes of Fatal Injuries: A Systematic Review and Meta-Analysis.
Alpert HR, Slater ME, Yoon YH, Chen CM, Winstanley N, Esser MB
Am J Prev Med 2022 Aug;63(2):286-300. Epub 2022 May 15 doi: 10.1016/j.amepre.2022.03.025. PMID: 35581102Free PMC Article
Time perception and alcohol use: A systematic review.
Nuyens FM, Billieux J, Maurage P
Neurosci Biobehav Rev 2021 Aug;127:377-403. Epub 2021 Apr 29 doi: 10.1016/j.neubiorev.2021.04.027. PMID: 33933506
Eye Tracking Studies Exploring Cognitive and Affective Processes among Alcohol Drinkers: a Systematic Review and Perspectives.
Maurage P, Bollen Z, Masson N, D'Hondt F
Neuropsychol Rev 2021 Mar;31(1):167-201. Epub 2020 Oct 25 doi: 10.1007/s11065-020-09458-0. PMID: 33099714
Recommendation for a definition of acute symptomatic seizure.
Beghi E, Carpio A, Forsgren L, Hesdorffer DC, Malmgren K, Sander JW, Tomson T, Hauser WA
Epilepsia 2010 Apr;51(4):671-5. Epub 2009 Sep 3 doi: 10.1111/j.1528-1167.2009.02285.x. PMID: 19732133

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