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Chronic renal insufficiency

MedGen UID:
140787
•Concept ID:
C0403447
•
Disease or Syndrome
Synonyms: Chronic Kidney Insufficiencies; Chronic Kidney Insufficiency; Chronic Renal Insufficiencies; Chronic Renal Insufficiency; Kidney Insufficiencies, Chronic; Kidney Insufficiency, Chronic; Renal Insufficiencies, Chronic; Renal Insufficiency, Chronic
SNOMED CT: Chronic renal impairment (709044004); Chronic renal insufficiency (723190009)

Definition

Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic renal insufficiency

Professional guidelines

PubMed

Restless Legs Syndrome: Contemporary Diagnosis and Treatment.
Gossard TR, Trotti LM, Videnovic A, St Louis EK
Neurotherapeutics 2021 Jan;18(1):140-155. Epub 2021 Apr 20 doi: 10.1007/s13311-021-01019-4. PMID: 33880737Free PMC Article
Proteomics and Metabolomics in Kidney Disease, including Insights into Etiology, Treatment, and Prevention.
Dubin RF, Rhee EP
Clin J Am Soc Nephrol 2020 Mar 6;15(3):404-411. Epub 2019 Oct 21 doi: 10.2215/CJN.07420619. PMID: 31636087Free PMC Article
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure.
Davison SN
Clin J Am Soc Nephrol 2019 Jun 7;14(6):917-931. Epub 2019 Mar 4 doi: 10.2215/CJN.05180418. PMID: 30833302Free PMC Article

Recent clinical studies

Etiology

KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease.
Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group
Kidney Int 2024 Apr;105(4S):S117-S314. doi: 10.1016/j.kint.2023.10.018. PMID: 38490803
KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease.
Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group
Kidney Int 2022 Nov;102(5S):S1-S127. doi: 10.1016/j.kint.2022.06.008. PMID: 36272764
Chronic Kidney Disease.
Charles C, Ferris AH
Prim Care 2020 Dec;47(4):585-595. Epub 2020 Sep 25 doi: 10.1016/j.pop.2020.08.001. PMID: 33121630
Chronic Kidney Disease.
Ammirati AL
Rev Assoc Med Bras (1992) 2020 Jan 13;66Suppl 1(Suppl 1):s03-s09. doi: 10.1590/1806-9282.66.S1.3. PMID: 31939529
Chronic kidney disease.
Drawz P, Rahman M
Ann Intern Med 2015 Jun 2;162(11):ITC1-16. doi: 10.7326/AITC201506020. PMID: 26030647

Diagnosis

KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease.
Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group
Kidney Int 2024 Apr;105(4S):S117-S314. doi: 10.1016/j.kint.2023.10.018. PMID: 38490803
Pediatric Chronic Kidney Disease.
Panzarino V, Lesser J, Cassani FA
Adv Pediatr 2022 Aug;69(1):123-132. doi: 10.1016/j.yapd.2022.03.008. PMID: 35985704
Defining AKD: The Spectrum of AKI, AKD, and CKD.
Levey AS
Nephron 2022;146(3):302-305. Epub 2021 Jun 24 doi: 10.1159/000516647. PMID: 34167119
Chronic Kidney Disease.
Charles C, Ferris AH
Prim Care 2020 Dec;47(4):585-595. Epub 2020 Sep 25 doi: 10.1016/j.pop.2020.08.001. PMID: 33121630
Chronic kidney disease.
Drawz P, Rahman M
Ann Intern Med 2015 Jun 2;162(11):ITC1-16. doi: 10.7326/AITC201506020. PMID: 26030647

Therapy

Protein restriction for diabetic kidney disease.
Jiang S, Fang J, Li W
Cochrane Database Syst Rev 2023 Jan 3;1(1):CD014906. doi: 10.1002/14651858.CD014906.pub2. PMID: 36594428Free PMC Article
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR
Int J Epidemiol 2022 Jan 6;50(6):1995-2010. Epub 2021 Oct 20 doi: 10.1093/ije/dyab203. PMID: 34999880Free PMC Article
Impact of physical exercise in patients with chronic kidney disease: Sistematic review and meta-analysis.
Villanego F, Naranjo J, Vigara LA, Cazorla JM, Montero ME, García T, Torrado J, Mazuecos A
Nefrologia (Engl Ed) 2020 May-Jun;40(3):237-252. Epub 2020 Apr 15 doi: 10.1016/j.nefro.2020.01.002. PMID: 32305232
Physical activity in chronic kidney disease and the EXerCise Introduction To Enhance trial.
Mallamaci F, Pisano A, Tripepi G
Nephrol Dial Transplant 2020 Mar 1;35(Suppl 2):ii18-ii22. doi: 10.1093/ndt/gfaa012. PMID: 32162664Free PMC Article
Protein Nutrition and Malnutrition in CKD and ESRD.
Zha Y, Qian Q
Nutrients 2017 Feb 27;9(3) doi: 10.3390/nu9030208. PMID: 28264439Free PMC Article

Prognosis

Ambient air pollution and incidence, progression to multimorbidity and death of hypertension, diabetes, and chronic kidney disease: A national prospective cohort.
Wu G, Cai M, Wang C, Zou H, Wang X, Hua J, Lin H
Sci Total Environ 2023 Jul 10;881:163406. Epub 2023 Apr 11 doi: 10.1016/j.scitotenv.2023.163406. PMID: 37054795
The prediction of in-hospital mortality in chronic kidney disease patients with coronary artery disease using machine learning models.
Ye Z, An S, Gao Y, Xie E, Zhao X, Guo Z, Li Y, Shen N, Ren J, Zheng J
Eur J Med Res 2023 Jan 18;28(1):33. doi: 10.1186/s40001-023-00995-x. PMID: 36653875Free PMC Article
Global, Regional, and National Burden of Diabetes-Related Chronic Kidney Disease From 1990 to 2019.
Deng Y, Li N, Wu Y, Wang M, Yang S, Zheng Y, Deng X, Xiang D, Zhu Y, Xu P, Zhai Z, Zhang D, Dai Z, Gao J
Front Endocrinol (Lausanne) 2021;12:672350. Epub 2021 Jul 1 doi: 10.3389/fendo.2021.672350. PMID: 34276558Free PMC Article
Update on Anemia in ESRD and Earlier Stages of CKD: Core Curriculum 2018.
Fishbane S, Spinowitz B
Am J Kidney Dis 2018 Mar;71(3):423-435. Epub 2018 Jan 11 doi: 10.1053/j.ajkd.2017.09.026. PMID: 29336855
Cardiovascular Disease Consequences of CKD.
Go AS
Semin Nephrol 2016 Jul;36(4):293-304. doi: 10.1016/j.semnephrol.2016.05.006. PMID: 27475660

Clinical prediction guides

Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study.
Slieker RC, van der Heijden AAWA, Siddiqui MK, Langendoen-Gort M, Nijpels G, Herings R, Feenstra TL, Moons KGM, Bell S, Elders PJ, 't Hart LM, Beulens JWJ
BMJ 2021 Sep 28;374:n2134. doi: 10.1136/bmj.n2134. PMID: 34583929Free PMC Article
Predicting Contrast-Induced Renal Complications.
Kroll RG, Yelavarthy P, Menees DS, Sutton NR
Interv Cardiol Clin 2020 Jul;9(3):321-333. Epub 2020 May 11 doi: 10.1016/j.iccl.2020.02.003. PMID: 32471673
Proteomics and Metabolomics in Kidney Disease, including Insights into Etiology, Treatment, and Prevention.
Dubin RF, Rhee EP
Clin J Am Soc Nephrol 2020 Mar 6;15(3):404-411. Epub 2019 Oct 21 doi: 10.2215/CJN.07420619. PMID: 31636087Free PMC Article
GFR Slope as a Surrogate End Point for Kidney Disease Progression in Clinical Trials: A Meta-Analysis of Treatment Effects of Randomized Controlled Trials.
Inker LA, Heerspink HJL, Tighiouart H, Levey AS, Coresh J, Gansevoort RT, Simon AL, Ying J, Beck GJ, Wanner C, Floege J, Li PK, Perkovic V, Vonesh EF, Greene T
J Am Soc Nephrol 2019 Sep;30(9):1735-1745. Epub 2019 Jul 10 doi: 10.1681/ASN.2019010007. PMID: 31292197Free PMC Article
Interleukin-18.
Wang S, Chen F, Yang S, Shi J
Int Heart J 2018 Jul 31;59(4):786-790. Epub 2018 Jul 18 doi: 10.1536/ihj.17-154. PMID: 30022770

Recent systematic reviews

A systematic review of the efficacy and safety of anticoagulants in advanced chronic kidney disease.
Parker K, Hartemink J, Saha A, Mitra R, Lewis P, Power A, Choudhuri S, Mitra S, Thachil J
J Nephrol 2022 Nov;35(8):2015-2033. Epub 2022 Aug 25 doi: 10.1007/s40620-022-01413-x. PMID: 36006608Free PMC Article
Impact of physical exercise in patients with chronic kidney disease: Sistematic review and meta-analysis.
Villanego F, Naranjo J, Vigara LA, Cazorla JM, Montero ME, García T, Torrado J, Mazuecos A
Nefrologia (Engl Ed) 2020 May-Jun;40(3):237-252. Epub 2020 Apr 15 doi: 10.1016/j.nefro.2020.01.002. PMID: 32305232
Vancomycin and the Risk of AKI: A Systematic Review and Meta-Analysis.
Sinha Ray A, Haikal A, Hammoud KA, Yu ASL
Clin J Am Soc Nephrol 2016 Dec 7;11(12):2132-2140. Epub 2016 Nov 28 doi: 10.2215/CJN.05920616. PMID: 27895134Free PMC Article
Insulin resistance in chronic kidney disease: a systematic review.
Spoto B, Pisano A, Zoccali C
Am J Physiol Renal Physiol 2016 Dec 1;311(6):F1087-F1108. Epub 2016 Oct 5 doi: 10.1152/ajprenal.00340.2016. PMID: 27707707
Global Prevalence of Chronic Kidney Disease - A Systematic Review and Meta-Analysis.
Hill NR, Fatoba ST, Oke JL, Hirst JA, O'Callaghan CA, Lasserson DS, Hobbs FD
PLoS One 2016;11(7):e0158765. Epub 2016 Jul 6 doi: 10.1371/journal.pone.0158765. PMID: 27383068Free PMC Article

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