U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

End-stage renal disease

MedGen UID:
9637
•Concept ID:
C0022661
•
Disease or Syndrome
Synonyms: Chronic Kidney Failure; Chronic Renal Failure; Disease, End-Stage Kidney; Disease, End-Stage Renal; End Stage Kidney Disease; End Stage Renal Disease; End-Stage Kidney Disease; End-Stage Renal Disease; End-Stage Renal Failure; ESRD; Kidney Disease, End-Stage; Kidney Failure, Chronic; Renal Disease, End Stage; Renal Disease, End-Stage; Renal Failure, Chronic; Renal Failure, End Stage; Renal Failure, End-Stage
SNOMED CT: ESRF - End stage renal failure (46177005); ESCRF - End stage chronic renal failure (46177005); ESRD - End stage renal disease (46177005); Chronic renal failure syndrome (90688005); End stage chronic renal failure (46177005); End-stage renal disease (46177005); CRF - Chronic renal failure (90688005); Chronic renal failure (90688005); End stage kidney disease (46177005)

Definition

Impairment of the renal function due to chronic kidney damage. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnd-stage renal disease

Professional guidelines

PubMed

Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment.
Samsu N
Biomed Res Int 2021;2021:1497449. Epub 2021 Jul 8 doi: 10.1155/2021/1497449. PMID: 34307650Free PMC Article
Cognitive Impairment in CKD: Pathophysiology, Management, and Prevention.
Drew DA, Weiner DE, Sarnak MJ
Am J Kidney Dis 2019 Dec;74(6):782-790. Epub 2019 Aug 1 doi: 10.1053/j.ajkd.2019.05.017. PMID: 31378643Free PMC Article
Classification and Differential Diagnosis of Diabetic Nephropathy.
Qi C, Mao X, Zhang Z, Wu H
J Diabetes Res 2017;2017:8637138. Epub 2017 Feb 20 doi: 10.1155/2017/8637138. PMID: 28316995Free PMC Article

Recent clinical studies

Etiology

The link between homocysteine, folic acid and vitamin B12 in chronic kidney disease.
Angelini A, Cappuccilli ML, Magnoni G, Croci Chiocchini AL, Aiello V, Napoletano A, Iacovella F, Troiano A, Mancini R, Capelli I, Cianciolo G
G Ital Nefrol 2021 Aug 30;38(4) PMID: 34469084
Carnosine and Diabetic Nephropathy.
Peters V, Yard B, Schmitt CP
Curr Med Chem 2020;27(11):1801-1812. doi: 10.2174/0929867326666190326111851. PMID: 30914013
Pregnancy and End-Stage Renal Disease.
Tangren J, Nadel M, Hladunewich MA
Blood Purif 2018;45(1-3):194-200. Epub 2018 Jan 26 doi: 10.1159/000485157. PMID: 29478065
Perioperative Management of Patients With End-Stage Renal Disease.
Kanda H, Hirasaki Y, Iida T, Kanao-Kanda M, Toyama Y, Chiba T, Kunisawa T
J Cardiothorac Vasc Anesth 2017 Dec;31(6):2251-2267. Epub 2017 Apr 13 doi: 10.1053/j.jvca.2017.04.019. PMID: 28803771
Live-donor nephrectomy.
Rocca JP, Davis E, Edye M
Mt Sinai J Med 2012 May-Jun;79(3):330-41. doi: 10.1002/msj.21317. PMID: 22678857

Diagnosis

Kidney disease in diabetes: From mechanisms to clinical presentation and treatment strategies.
Ricciardi CA, Gnudi L
Metabolism 2021 Nov;124:154890. Epub 2021 Sep 22 doi: 10.1016/j.metabol.2021.154890. PMID: 34560098
Penile Calciphylaxis.
Gaillet A, Luque Y
Urology 2020 Jun;140:e8-e9. Epub 2020 Mar 16 doi: 10.1016/j.urology.2020.03.003. PMID: 32194088
Chronic Renal Therapy.
Flagg AJ
Nurs Clin North Am 2018 Dec;53(4):511-519. Epub 2018 Oct 11 doi: 10.1016/j.cnur.2018.07.002. PMID: 30388977
Pregnancy and End-Stage Renal Disease.
Tangren J, Nadel M, Hladunewich MA
Blood Purif 2018;45(1-3):194-200. Epub 2018 Jan 26 doi: 10.1159/000485157. PMID: 29478065
Perioperative Management of Patients With End-Stage Renal Disease.
Kanda H, Hirasaki Y, Iida T, Kanao-Kanda M, Toyama Y, Chiba T, Kunisawa T
J Cardiothorac Vasc Anesth 2017 Dec;31(6):2251-2267. Epub 2017 Apr 13 doi: 10.1053/j.jvca.2017.04.019. PMID: 28803771

Therapy

Novel Therapies for ANCA-associated Vasculitis.
Monti S, Brandolino F, Milanesi A, Xoxi B, Delvino P, Montecucco C
Curr Rheumatol Rep 2021 Apr 28;23(6):38. doi: 10.1007/s11926-021-01010-0. PMID: 33909172
Exercise Training and Outcomes in Hemodialysis Patients: Systematic Review and Meta-Analysis.
Huang M, Lv A, Wang J, Xu N, Ma G, Zhai Z, Zhang B, Gao J, Ni C
Am J Nephrol 2019;50(4):240-254. Epub 2019 Aug 27 doi: 10.1159/000502447. PMID: 31454822
Angiotensin-Converting Enzyme Inhibitors in Hypertension: To Use or Not to Use?
Messerli FH, Bangalore S, Bavishi C, Rimoldi SF
J Am Coll Cardiol 2018 Apr 3;71(13):1474-1482. doi: 10.1016/j.jacc.2018.01.058. PMID: 29598869
Protein Nutrition and Malnutrition in CKD and ESRD.
Zha Y, Qian Q
Nutrients 2017 Feb 27;9(3) doi: 10.3390/nu9030208. PMID: 28264439Free PMC Article
Acupuncture for insomnia.
Cheuk DK, Yeung WF, Chung KF, Wong V
Cochrane Database Syst Rev 2012 Sep 12;(9):CD005472. doi: 10.1002/14651858.CD005472.pub3. PMID: 22972087

Prognosis

Association of Blood Pressure Lowering With Mortality and Cardiovascular Disease Across Blood Pressure Levels: A Systematic Review and Meta-analysis.
Brunström M, Carlberg B
JAMA Intern Med 2018 Jan 1;178(1):28-36. doi: 10.1001/jamainternmed.2017.6015. PMID: 29131895Free PMC Article
Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk of developing type 2 diabetes mellitus.
Hemmingsen B, Gimenez-Perez G, Mauricio D, Roqué I Figuls M, Metzendorf MI, Richter B
Cochrane Database Syst Rev 2017 Dec 4;12(12):CD003054. doi: 10.1002/14651858.CD003054.pub4. PMID: 29205264Free PMC Article
The frequency and outcome of lupus nephritis: results from an international inception cohort study.
Hanly JG, O'Keeffe AG, Su L, Urowitz MB, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Clarke AE, Wallace DJ, Merrill JT, Isenberg DA, Rahman A, Ginzler EM, Fortin P, Gladman DD, Sanchez-Guerrero J, Petri M, Bruce IN, Dooley MA, Ramsey-Goldman R, Aranow C, Alarcón GS, Fessler BJ, Steinsson K, Nived O, Sturfelt GK, Manzi S, Khamashta MA, van Vollenhoven RF, Zoma AA, Ramos-Casals M, Ruiz-Irastorza G, Lim SS, Stoll T, Inanc M, Kalunian KC, Kamen DL, Maddison P, Peschken CA, Jacobsen S, Askanase A, Theriault C, Thompson K, Farewell V
Rheumatology (Oxford) 2016 Feb;55(2):252-62. Epub 2015 Sep 5 doi: 10.1093/rheumatology/kev311. PMID: 26342222Free PMC Article
Calcium and Sudden Cardiac Death in End-Stage Renal Disease.
Kim ED, Parekh RS
Semin Dial 2015 Nov-Dec;28(6):624-35. Epub 2015 Aug 9 doi: 10.1111/sdi.12419. PMID: 26257009
Perioperative Implications of End-stage Renal Disease in Orthopaedic Surgery.
Carlo JO, Phisitkul P, Phisitkul K, Reddy S, Amendola A
J Am Acad Orthop Surg 2015 Feb;23(2):107-18. doi: 10.5435/JAAOS-D-13-00221. PMID: 25624363

Clinical prediction guides

Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study.
Slieker RC, van der Heijden AAWA, Siddiqui MK, Langendoen-Gort M, Nijpels G, Herings R, Feenstra TL, Moons KGM, Bell S, Elders PJ, 't Hart LM, Beulens JWJ
BMJ 2021 Sep 28;374:n2134. doi: 10.1136/bmj.n2134. PMID: 34583929Free PMC Article
Systemic lupus erythematosus, lupus nephritis and end-stage renal disease: a pragmatic review mapping disease severity and progression.
Mahajan A, Amelio J, Gairy K, Kaur G, Levy RA, Roth D, Bass D
Lupus 2020 Aug;29(9):1011-1020. Epub 2020 Jun 22 doi: 10.1177/0961203320932219. PMID: 32571142Free PMC Article
Depression in dialysis patients.
King-Wing Ma T, Kam-Tao Li P
Nephrology (Carlton) 2016 Aug;21(8):639-46. doi: 10.1111/nep.12742. PMID: 26860073
The PROPKD Score: A New Algorithm to Predict Renal Survival in Autosomal Dominant Polycystic Kidney Disease.
Cornec-Le Gall E, Audrézet MP, Rousseau A, Hourmant M, Renaudineau E, Charasse C, Morin MP, Moal MC, Dantal J, Wehbe B, Perrichot R, Frouget T, Vigneau C, Potier J, Jousset P, Guillodo MP, Siohan P, Terki N, Sawadogo T, Legrand D, Menoyo-Calonge V, Benarbia S, Besnier D, Longuet H, Férec C, Le Meur Y
J Am Soc Nephrol 2016 Mar;27(3):942-51. Epub 2015 Jul 6 doi: 10.1681/ASN.2015010016. PMID: 26150605Free PMC Article
Renal Function and Transplantation in Liver Disease.
Parajuli S, Foley D, Djamali A, Mandelbrot D
Transplantation 2015 Sep;99(9):1756-64. doi: 10.1097/TP.0000000000000820. PMID: 26308413

Recent systematic reviews

Diagnosis, prevalence, and mortality of sarcopenia in dialysis patients: a systematic review and meta-analysis.
Shu X, Lin T, Wang H, Zhao Y, Jiang T, Peng X, Yue J
J Cachexia Sarcopenia Muscle 2022 Feb;13(1):145-158. Epub 2022 Jan 5 doi: 10.1002/jcsm.12890. PMID: 34989172Free PMC Article
Comparative Effectiveness of Glucose-Lowering Drugs for Type 2 Diabetes: A Systematic Review and Network Meta-analysis.
Tsapas A, Avgerinos I, Karagiannis T, Malandris K, Manolopoulos A, Andreadis P, Liakos A, Matthews DR, Bekiari E
Ann Intern Med 2020 Aug 18;173(4):278-286. Epub 2020 Jun 30 doi: 10.7326/M20-0864. PMID: 32598218
Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis.
Chuasuwan A, Pooripussarakul S, Thakkinstian A, Ingsathit A, Pattanaprateep O
Health Qual Life Outcomes 2020 Jun 18;18(1):191. doi: 10.1186/s12955-020-01449-2. PMID: 32552800Free PMC Article
Exercise Training and Outcomes in Hemodialysis Patients: Systematic Review and Meta-Analysis.
Huang M, Lv A, Wang J, Xu N, Ma G, Zhai Z, Zhang B, Gao J, Ni C
Am J Nephrol 2019;50(4):240-254. Epub 2019 Aug 27 doi: 10.1159/000502447. PMID: 31454822
Acupuncture for insomnia.
Cheuk DK, Yeung WF, Chung KF, Wong V
Cochrane Database Syst Rev 2012 Sep 12;(9):CD005472. doi: 10.1002/14651858.CD005472.pub3. PMID: 22972087

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...