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Pars planitis

MedGen UID:
14623
Concept ID:
C0030593
Disease or Syndrome
Synonym: Familial pars planitis (subtype)
SNOMED CT: Posterior cyclitis (314428001); Pars planitis (45688009)
 
Monarch Initiative: MONDO:0011644
OMIM®: 606177

Definition

An inflammatory disorder of the cilliary body in the uvea that affects healthy, younger individuals who are often asymptomatic. It has a long clinical course with relapses and remissions. Symptoms include mildly decreased vision and floaters. It may be associated with autoimmune disorders. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPars planitis

Professional guidelines

PubMed

Ozdemir HB, Ozdal PC
Graefes Arch Clin Exp Ophthalmol 2022 Feb;260(2):561-569. Epub 2021 Sep 27 doi: 10.1007/s00417-021-05398-4. PMID: 34568953
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:268-274. Epub 2021 Apr 15 doi: 10.1016/j.ajo.2021.03.045. PMID: 33845006Free PMC Article
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:159-164. Epub 2021 Apr 9 doi: 10.1016/j.ajo.2021.03.054. PMID: 33839089Free PMC Article

Recent clinical studies

Etiology

Khochtali S, Ozdal P, AlBloushi AF, Nabi W, Khairallah M
Ocul Immunol Inflamm 2023 Dec;31(10):1915-1929. Epub 2023 Dec 14 doi: 10.1080/09273948.2023.2279683. PMID: 37976519
Teo AYT, Betzler BK, Hua KLQ, Chen EJ, Gupta V, Agrawal R
Ocul Immunol Inflamm 2023 Jul;31(5):1041-1060. Epub 2022 Jun 27 doi: 10.1080/09273948.2022.2070503. PMID: 35759636
Maleki A, Anesi SD, Look-Why S, Manhapra A, Foster CS
Surv Ophthalmol 2022 Mar-Apr;67(2):510-529. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.006. PMID: 34181974
Babu BM, Rathinam SR
Indian J Ophthalmol 2010 Jan-Feb;58(1):21-7. doi: 10.4103/0301-4738.58469. PMID: 20029143Free PMC Article
Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PMID: 16196117Free PMC Article

Diagnosis

Khochtali S, Ozdal P, AlBloushi AF, Nabi W, Khairallah M
Ocul Immunol Inflamm 2023 Dec;31(10):1915-1929. Epub 2023 Dec 14 doi: 10.1080/09273948.2023.2279683. PMID: 37976519
Teo AYT, Betzler BK, Hua KLQ, Chen EJ, Gupta V, Agrawal R
Ocul Immunol Inflamm 2023 Jul;31(5):1041-1060. Epub 2022 Jun 27 doi: 10.1080/09273948.2022.2070503. PMID: 35759636
Maleki A, Anesi SD, Look-Why S, Manhapra A, Foster CS
Surv Ophthalmol 2022 Mar-Apr;67(2):510-529. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.006. PMID: 34181974
Babu BM, Rathinam SR
Indian J Ophthalmol 2010 Jan-Feb;58(1):21-7. doi: 10.4103/0301-4738.58469. PMID: 20029143Free PMC Article
Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PMID: 16196117Free PMC Article

Therapy

Ozdemir HB, Ozdal PC
Graefes Arch Clin Exp Ophthalmol 2022 Feb;260(2):561-569. Epub 2021 Sep 27 doi: 10.1007/s00417-021-05398-4. PMID: 34568953
Babu BM, Rathinam SR
Indian J Ophthalmol 2010 Jan-Feb;58(1):21-7. doi: 10.4103/0301-4738.58469. PMID: 20029143Free PMC Article
Fraunfelder FW
Drugs Today (Barc) 2007 Feb;43(2):117-23. doi: 10.1358/dot.2007.43.2.1050789. PMID: 17353948
Kadayifçilar S, Eldem B, Tumer B
J Pediatr Ophthalmol Strabismus 2003 Nov-Dec;40(6):335-40. doi: 10.3928/0191-3913-20031101-06. PMID: 14655981
Paul RH
Am J Ophthalmol 1988 May 15;105(5):519-22. doi: 10.1016/0002-9394(88)90244-9. PMID: 3285693

Prognosis

Malalis JF, Bhat P, Shapiro M, Goldstein DA
Ocul Immunol Inflamm 2017 Jun;25(3):344-348. Epub 2016 Feb 22 doi: 10.3109/09273948.2015.1125511. PMID: 26902143
Umur KA, Tayfun B, Oguzhan O
Curr Opin Ophthalmol 2012 Nov;23(6):477-84. doi: 10.1097/ICU.0b013e328358c7a6. PMID: 23014267
Babu BM, Rathinam SR
Indian J Ophthalmol 2010 Jan-Feb;58(1):21-7. doi: 10.4103/0301-4738.58469. PMID: 20029143Free PMC Article
Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PMID: 16196117Free PMC Article
Zein G, Berta A, Foster CS
Ocul Immunol Inflamm 2004 Jun;12(2):137-42. doi: 10.1080/09273940490895344. PMID: 15512983

Clinical prediction guides

Khochtali S, Ozdal P, AlBloushi AF, Nabi W, Khairallah M
Ocul Immunol Inflamm 2023 Dec;31(10):1915-1929. Epub 2023 Dec 14 doi: 10.1080/09273948.2023.2279683. PMID: 37976519
Ramtohul P, Iovino C, Au A, Bacci T, Pichi F, Corradetti G, Corvi F, Manoharan N, Marin AI, Tadayoni R, Sadda S, Freund KB, Sarraf D
Ophthalmol Retina 2022 Nov;6(11):1070-1079. Epub 2022 May 8 doi: 10.1016/j.oret.2022.05.001. PMID: 35545196
Papasavvas I, Gehrig B, Herbort CP Jr
Klin Monbl Augenheilkd 2021 Apr;238(4):458-468. Epub 2021 Feb 19 doi: 10.1055/a-1354-6452. PMID: 33607692
Przeździecka-Dołyk J, Węgrzyn A, Turno-Kręcicka A, Misiuk-Hojło M
Arch Immunol Ther Exp (Warsz) 2016 Apr;64(2):127-37. Epub 2015 Oct 5 doi: 10.1007/s00005-015-0361-y. PMID: 26438050Free PMC Article
Kadayifçilar S, Eldem B, Tumer B
J Pediatr Ophthalmol Strabismus 2003 Nov-Dec;40(6):335-40. doi: 10.3928/0191-3913-20031101-06. PMID: 14655981

Recent systematic reviews

Pato E, Muñoz-Fernández S, Francisco F, Abad MA, Maese J, Ortiz A, Carmona L; Uveitis Working Group from Spanish Society of Rheumatology
Semin Arthritis Rheum 2011 Feb;40(4):314-23. Epub 2010 Jul 24 doi: 10.1016/j.semarthrit.2010.05.008. PMID: 20656330

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