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Splenic hemangioma

MedGen UID:
151930
•Concept ID:
C0685201
•
Neoplastic Process
Synonyms: Angioma of Spleen; angioma of spleen; Angioma of the Spleen; angioma of the spleen; Hemangioma of spleen; Hemangioma of Spleen; hemangioma of spleen; Hemangioma of the Spleen; hemangioma of the spleen; Spleen Angioma; spleen angioma; Spleen Hemangioma; Spleen hemangioma; spleen hemangioma; Splenic Angioma; splenic angioma; Splenic Hemangioma; splenic hemangioma
SNOMED CT: Hemangioma of spleen (93472004)
 
HPO: HP:0410268
Monarch Initiative: MONDO:0002343

Definition

A hemangioma, a benign tumor of the vascular endothelial cells, that is located in the spleen. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSplenic hemangioma

Professional guidelines

PubMed

Hemangioma of the spleen: presentation, diagnosis, and management.
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Splenic lesions: sonographic patterns, follow-up, differential diagnosis.
Goerg C, Schwerk WB, Goerg K
Eur J Radiol 1991 Jul-Aug;13(1):59-66. doi: 10.1016/0720-048x(91)90058-4. PMID: 1889432

Recent clinical studies

Etiology

Splenic embolization for a giant splenic hemangioma in a child: a case report.
Choi W, Choi YB
BMC Pediatr 2018 Nov 12;18(1):354. doi: 10.1186/s12887-018-1331-4. PMID: 30419881Free PMC Article
Laparoscopic Partial Splenectomy: A Safe and Feasible Treatment for Splenic Benign Lesions.
Chen J, Yu S, Xu L
Surg Laparosc Endosc Percutan Tech 2018 Oct;28(5):287-290. doi: 10.1097/SLE.0000000000000568. PMID: 30180141
Hemangioma of the spleen: presentation, diagnosis, and management.
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Splenic lesions: sonographic patterns, follow-up, differential diagnosis.
Goerg C, Schwerk WB, Goerg K
Eur J Radiol 1991 Jul-Aug;13(1):59-66. doi: 10.1016/0720-048x(91)90058-4. PMID: 1889432
Microscopic patterns in surgically removed spleens.
Simu G, Bancu VE, Macavei I, Fazekas A, Tohati MT
Rom J Morphol Embryol 1991 Jan-Jun;37(1-2):81-6. PMID: 1801984

Diagnosis

Intense 18 F-PSMA-1007 Uptake of Splenic Hemangioma.
Jia G, Dong A, Cheng C, Zuo C
Clin Nucl Med 2024 Feb 1;49(2):e90-e92. Epub 2023 Nov 30 doi: 10.1097/RLU.0000000000004995. PMID: 38048527
Elevated 68Ga-FAPI Activity in Splenic Hemangioma and Pneumonia.
Liu H, Wang Y, Zhang W, Cai L, Chen Y
Clin Nucl Med 2021 Aug 1;46(8):694-696. doi: 10.1097/RLU.0000000000003638. PMID: 33826568
Vascular neoplasms and non-neoplastic vascular lesions of the spleen.
Sangiorgio VFI, Arber DA
Semin Diagn Pathol 2021 Mar;38(2):154-158. Epub 2020 Jul 8 doi: 10.1053/j.semdp.2020.07.001. PMID: 32674844
Splenic Hemangioma.
Erickson LA
Mayo Clin Proc 2019 May;94(5):926-927. doi: 10.1016/j.mayocp.2019.02.006. PMID: 31054618
Splenic hemangioma.
Disler DG, Chew FS
AJR Am J Roentgenol 1991 Jul;157(1):44. doi: 10.2214/ajr.157.1.2048536. PMID: 2048536

Therapy

Splenic embolization for a giant splenic hemangioma in a child: a case report.
Choi W, Choi YB
BMC Pediatr 2018 Nov 12;18(1):354. doi: 10.1186/s12887-018-1331-4. PMID: 30419881Free PMC Article
Laparoscopic Partial Splenectomy: A Safe and Feasible Treatment for Splenic Benign Lesions.
Chen J, Yu S, Xu L
Surg Laparosc Endosc Percutan Tech 2018 Oct;28(5):287-290. doi: 10.1097/SLE.0000000000000568. PMID: 30180141
Clinical application of partial splenic embolization.
Guan YS, Hu Y
ScientificWorldJournal 2014;2014:961345. Epub 2014 Nov 3 doi: 10.1155/2014/961345. PMID: 25538966Free PMC Article
Antiangiogenic therapy for a large splenic hemangioma.
Islam S, Newman EA, Strouse PJ, Geiger JD
Pediatr Surg Int 2005 Dec;21(12):1007-10. Epub 2005 Oct 8 doi: 10.1007/s00383-005-1533-3. PMID: 16215767
Intestinal obstruction caused by infarcted splenic hemangioma with renal vein thrombosis in a newborn: a case report.
Lee CH
Int Surg 2002 Jul-Sep;87(3):157-9. PMID: 12403090

Prognosis

Vascular neoplasms and non-neoplastic vascular lesions of the spleen.
Sangiorgio VFI, Arber DA
Semin Diagn Pathol 2021 Mar;38(2):154-158. Epub 2020 Jul 8 doi: 10.1053/j.semdp.2020.07.001. PMID: 32674844
A primary splenic angiosarcoma hepatic metastasis after splenectomy and its genomic alteration profile.
Cao L, Hong J, Wang Y, Yu J, Ma R, Li J, Wu J, Zheng S
Medicine (Baltimore) 2019 Jul;98(28):e16245. doi: 10.1097/MD.0000000000016245. PMID: 31305404Free PMC Article
Splenic embolization for a giant splenic hemangioma in a child: a case report.
Choi W, Choi YB
BMC Pediatr 2018 Nov 12;18(1):354. doi: 10.1186/s12887-018-1331-4. PMID: 30419881Free PMC Article
Hemangioma of the spleen: presentation, diagnosis, and management.
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Splenic lesions: sonographic patterns, follow-up, differential diagnosis.
Goerg C, Schwerk WB, Goerg K
Eur J Radiol 1991 Jul-Aug;13(1):59-66. doi: 10.1016/0720-048x(91)90058-4. PMID: 1889432

Clinical prediction guides

Laparoscopic partial splenectomy in a patient with splenic hemangioma after distal gastrectomy for a neuroendocrine tumor.
Namikawa T, Araki K, Utsunomiya M, Yokota K, Munekage M, Maeda H, Kitagawa H, Kobayashi M, Hanazaki K, Seo S
Clin J Gastroenterol 2024 Feb;17(1):29-33. Epub 2023 Oct 8 doi: 10.1007/s12328-023-01868-w. PMID: 37805948
Endoscopic ultrasound guided fine-needle aspiration of a splenic hemangioma with extramedullary hematopoiesis.
Hudson JB, Murad FM, Kunkel JE, Collins BT
Diagn Cytopathol 2013 Dec;41(12):1086-90. Epub 2011 Nov 18 doi: 10.1002/dc.21862. PMID: 22102556
The rasH2 transgenic mouse: nature of the model and mechanistic studies on tumorigenesis.
Tamaoki N
Toxicol Pathol 2001;29 Suppl:81-9. doi: 10.1080/019262301753178492. PMID: 11695564
Hemangioma of the spleen: presentation, diagnosis, and management.
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Splenic lesions: sonographic patterns, follow-up, differential diagnosis.
Goerg C, Schwerk WB, Goerg K
Eur J Radiol 1991 Jul-Aug;13(1):59-66. doi: 10.1016/0720-048x(91)90058-4. PMID: 1889432

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