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Hypoglossal nerve palsy

MedGen UID:
154395
•Concept ID:
C0585265
•
Disease or Syndrome
Synonyms: Hypoglossal Nerve Palsies; Hypoglossal Nerve Palsy; Palsies, Hypoglossal Nerve; Palsy, Hypoglossal Nerve
SNOMED CT: Twelfth cranial nerve palsy (307405000); Hypoglossal nerve palsy (307405000)

Definition

Partial or complete paralysis of the hypoglossal nerve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoglossal nerve palsy

Professional guidelines

PubMed

Surgical management of extracranial carotid artery aneurysms.
Skóra JP, Kurcz J, Korta K, Szyber P, Dorobisz TA, Dorobisz AT
Vasa 2016;45(3):223-8. doi: 10.1024/0301-1526/a000528. PMID: 27129067
Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients.
Shah AC, Barnes C, Spiekerman CF, Bollag LA
Anesth Analg 2015 Jan;120(1):105-120. doi: 10.1213/ANE.0000000000000495. PMID: 25625257Free PMC Article

Recent clinical studies

Etiology

Hypoglossal nerve palsy after SARS-CoV-2 vaccination - report of two cases.
Panholzer J, Kellermair L, Eggers C
BMC Neurol 2022 Nov 9;22(1):416. doi: 10.1186/s12883-022-02929-2. PMID: 36352369Free PMC Article
Radiation-induced hypoglossal nerve palsy after definitive radiotherapy for nasopharyngeal carcinoma: Clinical predictors and dose-toxicity relationship.
Chow JCH, Cheung KM, Au KH, Zee BCY, Lee J, Ngan RKC, Lee AWM, Yiu HHY, Li KWS, Leung AKC, Chan JCH, Lee FKH, Wong KH
Radiother Oncol 2019 Sep;138:93-98. Epub 2019 Jun 25 doi: 10.1016/j.radonc.2019.06.011. PMID: 31252300
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783
Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients.
Shah AC, Barnes C, Spiekerman CF, Bollag LA
Anesth Analg 2015 Jan;120(1):105-120. doi: 10.1213/ANE.0000000000000495. PMID: 25625257Free PMC Article

Diagnosis

Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783
Hypertrophic pachymeningitis.
Dziedzic T, Wojciechowski J, Nowak A, Marchel A
Childs Nerv Syst 2015 Jul;31(7):1025-31. Epub 2015 Mar 15 doi: 10.1007/s00381-015-2680-z. PMID: 25771924
Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients.
Shah AC, Barnes C, Spiekerman CF, Bollag LA
Anesth Analg 2015 Jan;120(1):105-120. doi: 10.1213/ANE.0000000000000495. PMID: 25625257Free PMC Article
Eagle's Syndrome.
Elimairi I, Baur DA, Altay MA, Quereshy FA, Minisandram A
Head Neck Pathol 2015 Dec;9(4):492-5. Epub 2014 Dec 24 doi: 10.1007/s12105-014-0599-4. PMID: 25537830Free PMC Article

Therapy

Hypoglossal nerve palsy after SARS-CoV-2 vaccination - report of two cases.
Panholzer J, Kellermair L, Eggers C
BMC Neurol 2022 Nov 9;22(1):416. doi: 10.1186/s12883-022-02929-2. PMID: 36352369Free PMC Article
Radiation-induced hypoglossal nerve palsy after definitive radiotherapy for nasopharyngeal carcinoma: Clinical predictors and dose-toxicity relationship.
Chow JCH, Cheung KM, Au KH, Zee BCY, Lee J, Ngan RKC, Lee AWM, Yiu HHY, Li KWS, Leung AKC, Chan JCH, Lee FKH, Wong KH
Radiother Oncol 2019 Sep;138:93-98. Epub 2019 Jun 25 doi: 10.1016/j.radonc.2019.06.011. PMID: 31252300
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Cranial nerve palsy following central neuraxial block in obstetrics - a review of the literature and analysis of 43 case reports.
Chambers DJ, Bhatia K
Int J Obstet Anesth 2017 May;31:13-26. Epub 2017 Feb 20 doi: 10.1016/j.ijoa.2017.02.003. PMID: 28343842
Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients.
Shah AC, Barnes C, Spiekerman CF, Bollag LA
Anesth Analg 2015 Jan;120(1):105-120. doi: 10.1213/ANE.0000000000000495. PMID: 25625257Free PMC Article

Prognosis

Isolated Hypoglossal Nerve Palsy as an Early Symptom of a Granular Cell Tumor.
Lemound J, Papadimas D, Skodda S, Tannapfel A, Alekseyev A, Kunkel M
Int J Environ Res Public Health 2022 Feb 25;19(5) doi: 10.3390/ijerph19052690. PMID: 35270381Free PMC Article
Hypoglossal Nerve Palsy After Anterior Cervical Spine Surgery: A Case Report and Literature Review.
Colón LF, Isaza J, Katsuura Y, Nuss D
JBJS Case Connect 2020 Apr-Jun;10(2):e0098. doi: 10.2106/JBJS.CC.19.00098. PMID: 32649097
Imaging Features of isolated hypoglossal nerve palsy.
Guarnizo A, Glikstein R, Torres C
J Neuroradiol 2020 Mar;47(2):136-150. Epub 2019 Apr 26 doi: 10.1016/j.neurad.2019.04.006. PMID: 31034896
Radiation-induced hypoglossal nerve palsy after definitive radiotherapy for nasopharyngeal carcinoma: Clinical predictors and dose-toxicity relationship.
Chow JCH, Cheung KM, Au KH, Zee BCY, Lee J, Ngan RKC, Lee AWM, Yiu HHY, Li KWS, Leung AKC, Chan JCH, Lee FKH, Wong KH
Radiother Oncol 2019 Sep;138:93-98. Epub 2019 Jun 25 doi: 10.1016/j.radonc.2019.06.011. PMID: 31252300
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783

Clinical prediction guides

A taxonomy for brainstem cavernous malformations: subtypes of medullary lesions.
Catapano JS, Rumalla K, Srinivasan VM, Lawrence PM, Larson Keil K, Lawton MT
J Neurosurg 2023 Jan 1;138(1):128-146. Epub 2022 May 20 doi: 10.3171/2022.3.JNS22626. PMID: 35594887
Radiation-induced hypoglossal nerve palsy after definitive radiotherapy for nasopharyngeal carcinoma: Clinical predictors and dose-toxicity relationship.
Chow JCH, Cheung KM, Au KH, Zee BCY, Lee J, Ngan RKC, Lee AWM, Yiu HHY, Li KWS, Leung AKC, Chan JCH, Lee FKH, Wong KH
Radiother Oncol 2019 Sep;138:93-98. Epub 2019 Jun 25 doi: 10.1016/j.radonc.2019.06.011. PMID: 31252300
Diagnostic, Surgical, and Postoperative Challenges of Neuroendocrine Tumors of the Neck: Clinical Experience and Literature Review.
Khan MM, Khan MI, Ali H, Kazmi T, Iqbal H
Ann Vasc Surg 2017 Nov;45:92-97. Epub 2017 Jul 6 doi: 10.1016/j.avsg.2017.06.128. PMID: 28688875
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783
Hypertrophic pachymeningitis.
Dziedzic T, Wojciechowski J, Nowak A, Marchel A
Childs Nerv Syst 2015 Jul;31(7):1025-31. Epub 2015 Mar 15 doi: 10.1007/s00381-015-2680-z. PMID: 25771924

Recent systematic reviews

Horner's syndrome following obstetric neuraxial blockade - a systematic review of the literature.
Chambers DJ, Bhatia K
Int J Obstet Anesth 2018 Aug;35:75-87. Epub 2018 Mar 17 doi: 10.1016/j.ijoa.2018.03.005. PMID: 29657082
A patient with an odontoid fracture and atrophy of the tongue: a case report and systematic review of the literature.
Kuitwaard K, Vandertop WP
Surg Neurol 2005 Dec;64(6):525-32, discussion 532-3. doi: 10.1016/j.surneu.2005.04.032. PMID: 16293473

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