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Unilateral vocal cord paralysis

MedGen UID:
155887
•Concept ID:
C0751575
•
Finding; Finding
Synonyms: Paralysis, Unilateral, Vocal Cord; Paralysis, Vocal Cord, Unilateral; Unilateral Paralysis, Vocal Cord; Unilateral Vocal Cord Paralysis; Vocal Cord Paralysis, Unilateral
 
HPO: HP:0008757

Definition

A loss of the ability to move the vocal fold on one side. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnilateral vocal cord paralysis

Conditions with this feature

X-linked intellectual disability, van Esch type
MedGen UID:
930741
•Concept ID:
C4305072
•
Disease or Syndrome
Van Esch-O'Driscoll syndrome (VEODS) is characterized by varying degrees of intellectual disability, moderate to severe short stature, microcephaly, hypogonadism, and variable congenital malformations (Van Esch et al., 2019).
See: Condition Record
X-linked intellectual disability, van Esch type

Professional guidelines

PubMed

Endoscopic arytenoid abduction lateropexy for the treatment of neonatal bilateral vocal cord paralysis - Long-term results.
Sztanó B, Bach Á, Matievics V, Erdélyi E, Szegesdi I, Wootten CT, Rovó L
Int J Pediatr Otorhinolaryngol 2019 Apr;119:147-150. Epub 2019 Jan 22 doi: 10.1016/j.ijporl.2019.01.032. PMID: 30708182
Voice quality improvement after management of unilateral vocal cord paralysis with different techniques.
Bihari A, Mészáros K, Reményi A, Lichtenberger G
Eur Arch Otorhinolaryngol 2006 Dec;263(12):1115-20. Epub 2006 Aug 9 doi: 10.1007/s00405-006-0116-9. PMID: 16896756
Vocal cord paralysis in small children: principles in management.
Tucker HM
Ann Otol Rhinol Laryngol 1986 Nov-Dec;95(6 Pt 1):618-21. doi: 10.1177/000348948609500615. PMID: 3789595

Recent clinical studies

Etiology

Extralaryngeal causes of unilateral vocal cord paralysis: Aetiology and prognosis.
Ortega Beltrá N, Martínez Ruíz de Apodaca P, Matarredona Quiles S, Nieto Curiel P, Dalmau Galofre J
Acta Otorrinolaringol Esp (Engl Ed) 2022 Nov-Dec;73(6):376-383. Epub 2022 Oct 10 doi: 10.1016/j.otoeng.2021.11.002. PMID: 36228989
Revisiting CT Signs of Unilateral Vocal Fold Paralysis: A Single, Blinded Study.
Bashir MH, Joyce C, Bolduan A, Sehgal V, Smith M, Charous SJ
AJNR Am J Neuroradiol 2022 Apr;43(4):592-596. Epub 2022 Mar 24 doi: 10.3174/ajnr.A7451. PMID: 35332018Free PMC Article
Pre- and post-operative high-speed videolaryngoscopy in unilateral vocal cord paralysis following autologous fat augmentation.
Gandhi S, Bhatta S, Ganesuni D, Ghanpur AD, Saindani SJ
Am J Otolaryngol 2021 Mar-Apr;42(2):102878. Epub 2021 Jan 4 doi: 10.1016/j.amjoto.2020.102878. PMID: 33418176
Laryngeal Manifestations of Neurofibromatosis.
Naunheim MR, Plotkin SR, Franco RA, Song PC
Otolaryngol Head Neck Surg 2016 Mar;154(3):494-7. Epub 2016 Jan 19 doi: 10.1177/0194599815626133. PMID: 26786267
Surgical Interventions for Pediatric Unilateral Vocal Cord Paralysis: A Systematic Review.
Butskiy O, Mistry B, Chadha NK
JAMA Otolaryngol Head Neck Surg 2015 Jul;141(7):654-60. doi: 10.1001/jamaoto.2015.0680. PMID: 25973887

Diagnosis

Extralaryngeal causes of unilateral vocal cord paralysis: Aetiology and prognosis.
Ortega Beltrá N, Martínez Ruíz de Apodaca P, Matarredona Quiles S, Nieto Curiel P, Dalmau Galofre J
Acta Otorrinolaringol Esp (Engl Ed) 2022 Nov-Dec;73(6):376-383. Epub 2022 Oct 10 doi: 10.1016/j.otoeng.2021.11.002. PMID: 36228989
Revisiting CT Signs of Unilateral Vocal Fold Paralysis: A Single, Blinded Study.
Bashir MH, Joyce C, Bolduan A, Sehgal V, Smith M, Charous SJ
AJNR Am J Neuroradiol 2022 Apr;43(4):592-596. Epub 2022 Mar 24 doi: 10.3174/ajnr.A7451. PMID: 35332018Free PMC Article
Pre- and post-operative high-speed videolaryngoscopy in unilateral vocal cord paralysis following autologous fat augmentation.
Gandhi S, Bhatta S, Ganesuni D, Ghanpur AD, Saindani SJ
Am J Otolaryngol 2021 Mar-Apr;42(2):102878. Epub 2021 Jan 4 doi: 10.1016/j.amjoto.2020.102878. PMID: 33418176
Congenital vocal cord paralysis.
Ada M, Isildak H, Saritzali G
J Craniofac Surg 2010 Jan;21(1):273-4. doi: 10.1097/SCS.0b013e3181c5a456. PMID: 20098198
Vocal cord paralysis.
Grundfast KM, Harley E
Otolaryngol Clin North Am 1989 Jun;22(3):569-97. PMID: 2657584

Therapy

Vocal cord paralysis following lithium button battery ingestion in children.
Duan Q, Zhang F, Wang G, Wang H, Li H, Zhao J, Zhang J, Ni X
Eur J Pediatr 2021 Apr;180(4):1059-1066. Epub 2020 Oct 13 doi: 10.1007/s00431-020-03830-1. PMID: 33048238
Two trajectories of functional recovery in thyroid surgery related unilateral vocal cord paralysis.
Pei YC, Lu YA, Wong AMK, Chuang HF, Li HY, Fang TJ
Surgery 2020 Oct;168(4):578-585. Epub 2020 Jun 28 doi: 10.1016/j.surg.2020.04.042. PMID: 32605836
Unilateral vocal cord paralysis after surgical closure of a patent ductus arteriosus in extremely preterm infants.
Pharande P, Karthigeyan S, Walker K, D'Cruz D, Badawi N, Luig M, Winlaw D, Popat H
J Paediatr Child Health 2017 Dec;53(12):1192-1198. Epub 2017 Jul 8 doi: 10.1111/jpc.13632. PMID: 28688160
Injection of basic fibroblast growth factor for unilateral vocal cord paralysis().
Kanazawa T, Kurakami K, Kashima K, Konomi U, Komazawa D, Nakamura K, Matsushima K, Akagi Y, Misawa K, Nishino H, Watanabe Y
Acta Otolaryngol 2017 Sep;137(9):962-967. Epub 2017 Apr 22 doi: 10.1080/00016489.2017.1314550. PMID: 28434284
Vocal cord medialization for unilateral paralysis associated with intrathoracic malignancies.
Kraus DH, Ali MK, Ginsberg RJ, Hughes CJ, Orlikoff RF, Rusch VW, Burt ME, McCormack PM, Bains MS
J Thorac Cardiovasc Surg 1996 Feb;111(2):334-9; discussion 339-41. doi: 10.1016/s0022-5223(96)70442-7. PMID: 8583806

Prognosis

Extralaryngeal causes of unilateral vocal cord paralysis: Aetiology and prognosis.
Ortega Beltrá N, Martínez Ruíz de Apodaca P, Matarredona Quiles S, Nieto Curiel P, Dalmau Galofre J
Acta Otorrinolaringol Esp (Engl Ed) 2022 Nov-Dec;73(6):376-383. Epub 2022 Oct 10 doi: 10.1016/j.otoeng.2021.11.002. PMID: 36228989
Revisiting CT Signs of Unilateral Vocal Fold Paralysis: A Single, Blinded Study.
Bashir MH, Joyce C, Bolduan A, Sehgal V, Smith M, Charous SJ
AJNR Am J Neuroradiol 2022 Apr;43(4):592-596. Epub 2022 Mar 24 doi: 10.3174/ajnr.A7451. PMID: 35332018Free PMC Article
Unilateral vocal cord paralysis after surgical closure of a patent ductus arteriosus in extremely preterm infants.
Pharande P, Karthigeyan S, Walker K, D'Cruz D, Badawi N, Luig M, Winlaw D, Popat H
J Paediatr Child Health 2017 Dec;53(12):1192-1198. Epub 2017 Jul 8 doi: 10.1111/jpc.13632. PMID: 28688160
Unilateral vocal cord paralysis: a review of CT findings, mediastinal causes, and the course of the recurrent laryngeal nerves.
Paquette CM, Manos DC, Psooy BJ
Radiographics 2012 May-Jun;32(3):721-40. doi: 10.1148/rg.323115129. PMID: 22582356
Medialization thyroplasty for unilateral vocal cord paralysis.
Herman C
AORN J 2002 Mar;75(3):512-22; quiz 524-6, 529-30. doi: 10.1016/s0001-2092(06)61173-3. PMID: 11921820

Clinical prediction guides

Revisiting CT Signs of Unilateral Vocal Fold Paralysis: A Single, Blinded Study.
Bashir MH, Joyce C, Bolduan A, Sehgal V, Smith M, Charous SJ
AJNR Am J Neuroradiol 2022 Apr;43(4):592-596. Epub 2022 Mar 24 doi: 10.3174/ajnr.A7451. PMID: 35332018Free PMC Article
Injection laryngoplasty in infants with unilateral vocal cord paralysis: A survey of ASPO members.
Jang M, Gregory S, Jabbour J, Robey TC, Sulman C, Chun R
Int J Pediatr Otorhinolaryngol 2020 Jan;128:109671. Epub 2019 Sep 6 doi: 10.1016/j.ijporl.2019.109671. PMID: 31756694
Laryngeal Manifestations of Neurofibromatosis.
Naunheim MR, Plotkin SR, Franco RA, Song PC
Otolaryngol Head Neck Surg 2016 Mar;154(3):494-7. Epub 2016 Jan 19 doi: 10.1177/0194599815626133. PMID: 26786267
Surgical Interventions for Pediatric Unilateral Vocal Cord Paralysis: A Systematic Review.
Butskiy O, Mistry B, Chadha NK
JAMA Otolaryngol Head Neck Surg 2015 Jul;141(7):654-60. doi: 10.1001/jamaoto.2015.0680. PMID: 25973887
Medialization thyroplasty for unilateral vocal cord paralysis.
Herman C
AORN J 2002 Mar;75(3):512-22; quiz 524-6, 529-30. doi: 10.1016/s0001-2092(06)61173-3. PMID: 11921820

Recent systematic reviews

The surgical treatment of unilateral vocal cord paralysis (UVCP): qualitative review analysis and meta-analysis study.
Granato F, Martelli F, Comini LV, Luparello P, Coscarelli S, Le Seac O, Carucci S, Graziani P, Santoro R, Alderotti G, Barillari MR, Mannelli G
Eur Arch Otorhinolaryngol 2019 Oct;276(10):2649-2659. Epub 2019 Aug 2 doi: 10.1007/s00405-019-05587-2. PMID: 31375895
Identifying the Prevalence of Dysphagia among Patients Diagnosed with Unilateral Vocal Fold Immobility.
Zhou D, Jafri M, Husain I
Otolaryngol Head Neck Surg 2019 Jun;160(6):955-964. Epub 2018 Dec 11 doi: 10.1177/0194599818815885. PMID: 30526299
A comparison of outcomes in interventions for unilateral vocal fold paralysis: A systematic review.
Siu J, Tam S, Fung K
Laryngoscope 2016 Jul;126(7):1616-24. Epub 2015 Oct 20 doi: 10.1002/lary.25739. PMID: 26485674
Surgical Interventions for Pediatric Unilateral Vocal Cord Paralysis: A Systematic Review.
Butskiy O, Mistry B, Chadha NK
JAMA Otolaryngol Head Neck Surg 2015 Jul;141(7):654-60. doi: 10.1001/jamaoto.2015.0680. PMID: 25973887
Vocal cord paralysis secondary to spontaneous internal carotid dissection: case report and systematic review of the literature.
Nguyen TT, Zhang H, Dziegielewski PT, Seemann R
J Otolaryngol Head Neck Surg 2013 May 13;42(1):34. doi: 10.1186/1916-0216-42-34. PMID: 23668480Free PMC Article

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