U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Eyelid sebaceous gland carcinoma

MedGen UID:
1612781
•Concept ID:
C4525405
•
Neoplastic Process
Synonyms: carcinoma of sebaceous gland of eyelid; Eyelid Sebaceous Gland Carcinoma; eyelid sebaceous gland carcinoma; Eyelid SGC; eyelid SGC; Sebaceous Gland Carcinoma of the Eyelid; sebaceous gland carcinoma of the eyelid; sebaceous gland of eyelid carcinoma
 
Monarch Initiative: MONDO:0021588

Definition

A sebaceous gland carcinoma affecting the eyelid. It arises from the meibomian glands, glands of Zeis, or glands associated with the caruncle. It usually affects elderly women and is characterized by high rate of local recurrence, regional, and distant metastases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEyelid sebaceous gland carcinoma

Professional guidelines

PubMed

Second primary tumors in retinoblastoma survivors: a study of 7 Asian Indian patients.
Kaliki S, Palkonda VAR
Int Ophthalmol 2020 Dec;40(12):3303-3308. Epub 2020 Jul 31 doi: 10.1007/s10792-020-01517-y. PMID: 32737729
Neoadjuvant Systemic Chemotherapy in the Management of Extensive Eyelid Sebaceous Gland Carcinoma: A study of 10 Cases.
Kaliki S, Ayyar A, Nair AG, Mishra DK, Reddy VA, Naik MN
Ophthalmic Plast Reconstr Surg 2016 Jan-Feb;32(1):35-9. doi: 10.1097/IOP.0000000000000398. PMID: 25675161

Recent clinical studies

Etiology

Development and validation of a nomogram to predict the recurrence of eyelid sebaceous gland carcinoma.
Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
Eyelid sebaceous gland carcinoma, validation of AJCC 8th edition T staging- a retrospective study from North India.
Sen S, Bhardwaj M, Jayaraj P, Bakhshi S, Pushker N, Kashyap S, Bajaj MS, Khandpur S
Acta Ophthalmol 2023 Feb;101(1):49-56. Epub 2022 Jun 24 doi: 10.1111/aos.15204. PMID: 35751173
Eyelid sebaceous gland carcinoma: An assessment of the T classification of the American Joint Committee of Cancer TNM staging system 8th versus 7th edition.
AlHammad F, Edward DP, Alkatan HM, Elkhamary S, Iuliano A, Maktabi A, Al-Horani SE, Al-Sheikh O, Al Hussain H, Strianese D
Eur J Ophthalmol 2021 Jul;31(4):2055-2063. Epub 2020 Jun 21 doi: 10.1177/1120672120936488. PMID: 32567368
Vimentin overexpression as a novel poor prognostic biomarker in eyelid sebaceous gland carcinoma.
Bhardwaj M, Sen S, Chosdol K, Bakhshi S, Pushker N, Sharma A, Kashyap S, Bajaj MS, Singh VK
Br J Ophthalmol 2020 Jun;104(6):879-884. Epub 2019 Apr 2 doi: 10.1136/bjophthalmol-2018-313285. PMID: 30940620
Sebaceous gland carcinoma of the eyelid: clinicopathological features and outcome in Asian Indians.
Kaliki S, Ayyar A, Dave TV, Ali MJ, Mishra DK, Naik MN
Eye (Lond) 2015 Jul;29(7):958-63. Epub 2015 May 22 doi: 10.1038/eye.2015.79. PMID: 25998946Free PMC Article

Diagnosis

Development and validation of a nomogram to predict the recurrence of eyelid sebaceous gland carcinoma.
Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
The effect of direct cell injury inflicted by cryotherapy on eyelid sebaceous gland carcinoma cells: An ex-vivo experimental study.
Alam MS, Banerjee P, Krishnakumar S
Indian J Ophthalmol 2022 Feb;70(2):630-633. doi: 10.4103/ijo.IJO_1814_21. PMID: 35086251Free PMC Article
Vimentin overexpression as a novel poor prognostic biomarker in eyelid sebaceous gland carcinoma.
Bhardwaj M, Sen S, Chosdol K, Bakhshi S, Pushker N, Sharma A, Kashyap S, Bajaj MS, Singh VK
Br J Ophthalmol 2020 Jun;104(6):879-884. Epub 2019 Apr 2 doi: 10.1136/bjophthalmol-2018-313285. PMID: 30940620
14-year case series of eyelid sebaceous gland carcinoma in Chinese patients and review of management.
Lam SC, Li EYM, Yuen HKL
Br J Ophthalmol 2018 Dec;102(12):1723-1727. Epub 2018 Feb 19 doi: 10.1136/bjophthalmol-2017-311533. PMID: 29459429
Sebaceous gland carcinoma of the eyelid: clinicopathological features and outcome in Asian Indians.
Kaliki S, Ayyar A, Dave TV, Ali MJ, Mishra DK, Naik MN
Eye (Lond) 2015 Jul;29(7):958-63. Epub 2015 May 22 doi: 10.1038/eye.2015.79. PMID: 25998946Free PMC Article

Therapy

The effect of direct cell injury inflicted by cryotherapy on eyelid sebaceous gland carcinoma cells: An ex-vivo experimental study.
Alam MS, Banerjee P, Krishnakumar S
Indian J Ophthalmol 2022 Feb;70(2):630-633. doi: 10.4103/ijo.IJO_1814_21. PMID: 35086251Free PMC Article
Neoadjuvant Systemic Chemotherapy in the Management of Extensive Eyelid Sebaceous Gland Carcinoma: A study of 10 Cases.
Kaliki S, Ayyar A, Nair AG, Mishra DK, Reddy VA, Naik MN
Ophthalmic Plast Reconstr Surg 2016 Jan-Feb;32(1):35-9. doi: 10.1097/IOP.0000000000000398. PMID: 25675161
Topical mitomycin-C for pagetoid invasion of the conjunctiva by eyelid sebaceous gland carcinoma.
Shields CL, Naseripour M, Shields JA, Eagle RC Jr
Ophthalmology 2002 Nov;109(11):2129-33. doi: 10.1016/s0161-6420(02)01239-3. PMID: 12414427

Prognosis

Development and validation of a nomogram to predict the recurrence of eyelid sebaceous gland carcinoma.
Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
Eyelid sebaceous gland carcinoma, validation of AJCC 8th edition T staging- a retrospective study from North India.
Sen S, Bhardwaj M, Jayaraj P, Bakhshi S, Pushker N, Kashyap S, Bajaj MS, Khandpur S
Acta Ophthalmol 2023 Feb;101(1):49-56. Epub 2022 Jun 24 doi: 10.1111/aos.15204. PMID: 35751173
Eyelid sebaceous gland carcinoma: An assessment of the T classification of the American Joint Committee of Cancer TNM staging system 8th versus 7th edition.
AlHammad F, Edward DP, Alkatan HM, Elkhamary S, Iuliano A, Maktabi A, Al-Horani SE, Al-Sheikh O, Al Hussain H, Strianese D
Eur J Ophthalmol 2021 Jul;31(4):2055-2063. Epub 2020 Jun 21 doi: 10.1177/1120672120936488. PMID: 32567368
Vimentin overexpression as a novel poor prognostic biomarker in eyelid sebaceous gland carcinoma.
Bhardwaj M, Sen S, Chosdol K, Bakhshi S, Pushker N, Sharma A, Kashyap S, Bajaj MS, Singh VK
Br J Ophthalmol 2020 Jun;104(6):879-884. Epub 2019 Apr 2 doi: 10.1136/bjophthalmol-2018-313285. PMID: 30940620
Sebaceous gland carcinoma of the eyelid: clinicopathological features and outcome in Asian Indians.
Kaliki S, Ayyar A, Dave TV, Ali MJ, Mishra DK, Naik MN
Eye (Lond) 2015 Jul;29(7):958-63. Epub 2015 May 22 doi: 10.1038/eye.2015.79. PMID: 25998946Free PMC Article

Clinical prediction guides

Development and validation of a nomogram to predict the recurrence of eyelid sebaceous gland carcinoma.
Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
Eyelid sebaceous gland carcinoma, validation of AJCC 8th edition T staging- a retrospective study from North India.
Sen S, Bhardwaj M, Jayaraj P, Bakhshi S, Pushker N, Kashyap S, Bajaj MS, Khandpur S
Acta Ophthalmol 2023 Feb;101(1):49-56. Epub 2022 Jun 24 doi: 10.1111/aos.15204. PMID: 35751173
Eyelid sebaceous gland carcinoma: An assessment of the T classification of the American Joint Committee of Cancer TNM staging system 8th versus 7th edition.
AlHammad F, Edward DP, Alkatan HM, Elkhamary S, Iuliano A, Maktabi A, Al-Horani SE, Al-Sheikh O, Al Hussain H, Strianese D
Eur J Ophthalmol 2021 Jul;31(4):2055-2063. Epub 2020 Jun 21 doi: 10.1177/1120672120936488. PMID: 32567368
Vimentin overexpression as a novel poor prognostic biomarker in eyelid sebaceous gland carcinoma.
Bhardwaj M, Sen S, Chosdol K, Bakhshi S, Pushker N, Sharma A, Kashyap S, Bajaj MS, Singh VK
Br J Ophthalmol 2020 Jun;104(6):879-884. Epub 2019 Apr 2 doi: 10.1136/bjophthalmol-2018-313285. PMID: 30940620
Sebaceous gland carcinoma of the eyelid: clinicopathological features and outcome in Asian Indians.
Kaliki S, Ayyar A, Dave TV, Ali MJ, Mishra DK, Naik MN
Eye (Lond) 2015 Jul;29(7):958-63. Epub 2015 May 22 doi: 10.1038/eye.2015.79. PMID: 25998946Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...