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Abnormal regional left ventricular contraction

MedGen UID:
1613859
Concept ID:
C4531093
Finding
HPO: HP:0031482

Definition

A wall motion abnormality observed upon left ventricular contraction that affects a specific region of the left ventricle. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal regional left ventricular contraction

Professional guidelines

PubMed

George SA, Brennan-McLean JA, Trampel KA, Rytkin E, Faye NR, Knollmann BC, Efimov IR
Am J Physiol Heart Circ Physiol 2023 Oct 1;325(4):H720-H728. Epub 2023 Aug 11 doi: 10.1152/ajpheart.00103.2023. PMID: 37566110
Corral Acero J, Schuster A, Zacur E, Lange T, Stiermaier T, Backhaus SJ, Thiele H, Bueno-Orovio A, Lamata P, Eitel I, Grau V
JACC Cardiovasc Imaging 2022 Sep;15(9):1563-1574. Epub 2022 Jan 12 doi: 10.1016/j.jcmg.2021.11.027. PMID: 35033494Free PMC Article
David D, Lang RM, Borow KM
Am Heart J 1988 Jul;116(1 Pt 1):235-47. doi: 10.1016/0002-8703(88)90284-0. PMID: 3293392

Recent clinical studies

Etiology

Nag S, Gollapudi SK, Del Rio CL, Spudich JA, McDowell R
Sci Adv 2023 Jul 28;9(30):eabo7622. doi: 10.1126/sciadv.abo7622. PMID: 37506209
Khalil F, Toya T, Madhavan M, Badawy M, Ahmad A, Kapa S, Mulpuru SK, Siontis KC, DeSimone CV, Deshmukh AJ, Cha YM, Friedman PA, Munger T, Asirvatham SJ, Killu AM
J Cardiovasc Electrophysiol 2022 Feb;33(2):274-283. Epub 2022 Jan 3 doi: 10.1111/jce.15331. PMID: 34911151
Picano E, Ciampi Q, Wierzbowska-Drabik K, Urluescu ML, Morrone D, Carpeggiani C
Cardiovasc Ultrasound 2018 Oct 2;16(1):22. doi: 10.1186/s12947-018-0141-z. PMID: 30285774Free PMC Article
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507
MacIver DH, Clark AL
J Card Fail 2016 Sep;22(9):731-7. Epub 2016 May 16 doi: 10.1016/j.cardfail.2016.03.020. PMID: 27090746

Diagnosis

Khalil F, Toya T, Madhavan M, Badawy M, Ahmad A, Kapa S, Mulpuru SK, Siontis KC, DeSimone CV, Deshmukh AJ, Cha YM, Friedman PA, Munger T, Asirvatham SJ, Killu AM
J Cardiovasc Electrophysiol 2022 Feb;33(2):274-283. Epub 2022 Jan 3 doi: 10.1111/jce.15331. PMID: 34911151
Tini G, Limite LR, Arcari L, Cacciotti L, Russo D, Sclafani M, Brunelli C, Volpe M, Autore C, Musumeci MB
Heart Fail Rev 2022 Jan;27(1):271-280. doi: 10.1007/s10741-020-09988-y. PMID: 32535741
Picano E, Ciampi Q, Wierzbowska-Drabik K, Urluescu ML, Morrone D, Carpeggiani C
Cardiovasc Ultrasound 2018 Oct 2;16(1):22. doi: 10.1186/s12947-018-0141-z. PMID: 30285774Free PMC Article
Benameur N, Caiani EG, Arous Y, Ben Abdallah N, Kraiem T
Cardiovasc Eng Technol 2018 Sep;9(3):377-393. Epub 2018 May 14 doi: 10.1007/s13239-018-0362-1. PMID: 29761408
Te Riele ASJM, Tandri H, Sanborn DM, Bluemke DA
JACC Cardiovasc Imaging 2015 May;8(5):597-611. doi: 10.1016/j.jcmg.2015.02.007. PMID: 25937197Free PMC Article

Therapy

Nag S, Gollapudi SK, Del Rio CL, Spudich JA, McDowell R
Sci Adv 2023 Jul 28;9(30):eabo7622. doi: 10.1126/sciadv.abo7622. PMID: 37506209
Khalil F, Toya T, Madhavan M, Badawy M, Ahmad A, Kapa S, Mulpuru SK, Siontis KC, DeSimone CV, Deshmukh AJ, Cha YM, Friedman PA, Munger T, Asirvatham SJ, Killu AM
J Cardiovasc Electrophysiol 2022 Feb;33(2):274-283. Epub 2022 Jan 3 doi: 10.1111/jce.15331. PMID: 34911151
Nguyên UC, Verzaal NJ, van Nieuwenhoven FA, Vernooy K, Prinzen FW
Europace 2018 Dec 1;20(12):1898-1909. doi: 10.1093/europace/euy035. PMID: 29771311
Muser D, Liang JJ, Witschey WR, Pathak RK, Castro S, Magnani S, Zado ES, Garcia FC, Desjardins B, Callans DJ, Frankel DS, Marchlinski FE, Santangeli P
Heart Rhythm 2017 Feb;14(2):166-175. Epub 2016 Nov 24 doi: 10.1016/j.hrthm.2016.11.014. PMID: 27890738
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507

Prognosis

Tini G, Limite LR, Arcari L, Cacciotti L, Russo D, Sclafani M, Brunelli C, Volpe M, Autore C, Musumeci MB
Heart Fail Rev 2022 Jan;27(1):271-280. doi: 10.1007/s10741-020-09988-y. PMID: 32535741
Benameur N, Caiani EG, Arous Y, Ben Abdallah N, Kraiem T
Cardiovasc Eng Technol 2018 Sep;9(3):377-393. Epub 2018 May 14 doi: 10.1007/s13239-018-0362-1. PMID: 29761408
Muser D, Liang JJ, Witschey WR, Pathak RK, Castro S, Magnani S, Zado ES, Garcia FC, Desjardins B, Callans DJ, Frankel DS, Marchlinski FE, Santangeli P
Heart Rhythm 2017 Feb;14(2):166-175. Epub 2016 Nov 24 doi: 10.1016/j.hrthm.2016.11.014. PMID: 27890738
MacIver DH, Clark AL
J Card Fail 2016 Sep;22(9):731-7. Epub 2016 May 16 doi: 10.1016/j.cardfail.2016.03.020. PMID: 27090746
Te Riele ASJM, Tandri H, Sanborn DM, Bluemke DA
JACC Cardiovasc Imaging 2015 May;8(5):597-611. doi: 10.1016/j.jcmg.2015.02.007. PMID: 25937197Free PMC Article

Clinical prediction guides

Tini G, Limite LR, Arcari L, Cacciotti L, Russo D, Sclafani M, Brunelli C, Volpe M, Autore C, Musumeci MB
Heart Fail Rev 2022 Jan;27(1):271-280. doi: 10.1007/s10741-020-09988-y. PMID: 32535741
Benameur N, Caiani EG, Arous Y, Ben Abdallah N, Kraiem T
Cardiovasc Eng Technol 2018 Sep;9(3):377-393. Epub 2018 May 14 doi: 10.1007/s13239-018-0362-1. PMID: 29761408
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507
Te Riele ASJM, Tandri H, Sanborn DM, Bluemke DA
JACC Cardiovasc Imaging 2015 May;8(5):597-611. doi: 10.1016/j.jcmg.2015.02.007. PMID: 25937197Free PMC Article
Corya BC
Am J Med 1977 Jul;63(1):10-20. doi: 10.1016/0002-9343(77)90113-9. PMID: 327801

Recent systematic reviews

Tini G, Limite LR, Arcari L, Cacciotti L, Russo D, Sclafani M, Brunelli C, Volpe M, Autore C, Musumeci MB
Heart Fail Rev 2022 Jan;27(1):271-280. doi: 10.1007/s10741-020-09988-y. PMID: 32535741

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