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Abnormal regional left ventricular contraction

MedGen UID:
1613859
•Concept ID:
C4531093
•
Finding
HPO: HP:0031482

Definition

A wall motion abnormality observed upon left ventricular contraction that affects a specific region of the left ventricle. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal regional left ventricular contraction

Professional guidelines

PubMed

Understanding and Improving Risk Assessment After Myocardial Infarction Using Automated Left Ventricular Shape Analysis.
Corral Acero J, Schuster A, Zacur E, Lange T, Stiermaier T, Backhaus SJ, Thiele H, Bueno-Orovio A, Lamata P, Eitel I, Grau V
JACC Cardiovasc Imaging 2022 Sep;15(9):1563-1574. Epub 2022 Jan 12 doi: 10.1016/j.jcmg.2021.11.027. PMID: 35033494Free PMC Article
Clinical utility of exercise, pacing, and pharmacologic stress testing for the noninvasive determination of myocardial contractility and reserve.
David D, Lang RM, Borow KM
Am Heart J 1988 Jul;116(1 Pt 1):235-47. doi: 10.1016/0002-8703(88)90284-0. PMID: 3293392
Anatomical vs "Functional" left ventricular aneurysm: angiographic differentiation and management implication.
Rösch J, Keller FS, Rahimtoola SH, McAnulty JH
Eur J Radiol 1981 Mar;1(1):30-45. PMID: 7338223

Recent clinical studies

Etiology

Left ventricular contractile reserve in stress echocardiography: the bright side of the force.
Picano E, Bombardini T, Kovačević Preradović T, Cortigiani L, Wierzbowska-Drabik K, Ciampi Q
Kardiol Pol 2019;77(2):164-172. Epub 2019 Jan 15 doi: 10.5603/KP.a2019.0002. PMID: 30644080
The new clinical standard of integrated quadruple stress echocardiography with ABCD protocol.
Picano E, Ciampi Q, Wierzbowska-Drabik K, Urluescu ML, Morrone D, Carpeggiani C
Cardiovasc Ultrasound 2018 Oct 2;16(1):22. doi: 10.1186/s12947-018-0141-z. PMID: 30285774Free PMC Article
Ventricular arrhythmias associated with left ventricular noncompaction: Electrophysiologic characteristics, mapping, and ablation.
Muser D, Liang JJ, Witschey WR, Pathak RK, Castro S, Magnani S, Zado ES, Garcia FC, Desjardins B, Callans DJ, Frankel DS, Marchlinski FE, Santangeli P
Heart Rhythm 2017 Feb;14(2):166-175. Epub 2016 Nov 24 doi: 10.1016/j.hrthm.2016.11.014. PMID: 27890738
Hemodialysis-induced regional left ventricular systolic dysfunction.
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507
Contractile Dysfunction in Sarcomeric Hypertrophic Cardiomyopathy.
MacIver DH, Clark AL
J Card Fail 2016 Sep;22(9):731-7. Epub 2016 May 16 doi: 10.1016/j.cardfail.2016.03.020. PMID: 27090746

Diagnosis

The new clinical standard of integrated quadruple stress echocardiography with ABCD protocol.
Picano E, Ciampi Q, Wierzbowska-Drabik K, Urluescu ML, Morrone D, Carpeggiani C
Cardiovasc Ultrasound 2018 Oct 2;16(1):22. doi: 10.1186/s12947-018-0141-z. PMID: 30285774Free PMC Article
Parametric Imaging for the Assessment of Cardiac Motion: A Review.
Benameur N, Caiani EG, Arous Y, Ben Abdallah N, Kraiem T
Cardiovasc Eng Technol 2018 Sep;9(3):377-393. Epub 2018 May 14 doi: 10.1007/s13239-018-0362-1. PMID: 29761408
Ventricular arrhythmias associated with left ventricular noncompaction: Electrophysiologic characteristics, mapping, and ablation.
Muser D, Liang JJ, Witschey WR, Pathak RK, Castro S, Magnani S, Zado ES, Garcia FC, Desjardins B, Callans DJ, Frankel DS, Marchlinski FE, Santangeli P
Heart Rhythm 2017 Feb;14(2):166-175. Epub 2016 Nov 24 doi: 10.1016/j.hrthm.2016.11.014. PMID: 27890738
Noninvasive Multimodality Imaging in ARVD/C.
Te Riele ASJM, Tandri H, Sanborn DM, Bluemke DA
JACC Cardiovasc Imaging 2015 May;8(5):597-611. doi: 10.1016/j.jcmg.2015.02.007. PMID: 25937197Free PMC Article
MRI myocardial tagging.
Reichek N
J Magn Reson Imaging 1999 Nov;10(5):609-16. doi: 10.1002/(sici)1522-2586(199911)10:5<609::aid-jmri4>3.0.co;2-2. PMID: 10548769

Therapy

Pathobiology of cardiac dyssynchrony and resynchronization therapy.
Nguyên UC, Verzaal NJ, van Nieuwenhoven FA, Vernooy K, Prinzen FW
Europace 2018 Dec 1;20(12):1898-1909. doi: 10.1093/europace/euy035. PMID: 29771311
Ventricular arrhythmias associated with left ventricular noncompaction: Electrophysiologic characteristics, mapping, and ablation.
Muser D, Liang JJ, Witschey WR, Pathak RK, Castro S, Magnani S, Zado ES, Garcia FC, Desjardins B, Callans DJ, Frankel DS, Marchlinski FE, Santangeli P
Heart Rhythm 2017 Feb;14(2):166-175. Epub 2016 Nov 24 doi: 10.1016/j.hrthm.2016.11.014. PMID: 27890738
Hemodialysis-induced regional left ventricular systolic dysfunction.
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507
Physiology of biventricular pacing.
Bilchick KC, Helm RH, Kass DA
Curr Cardiol Rep 2007 Sep;9(5):358-65. doi: 10.1007/BF02938362. PMID: 17877930
Determinants of improved left ventricular function after thrombolytic therapy in acute myocardial infarction.
Sheehan FH
J Am Coll Cardiol 1987 Apr;9(4):937-44. doi: 10.1016/s0735-1097(87)80252-8. PMID: 2951424

Prognosis

A systematic review on focal takotsubo syndrome: a not-so-small matter.
Tini G, Limite LR, Arcari L, Cacciotti L, Russo D, Sclafani M, Brunelli C, Volpe M, Autore C, Musumeci MB
Heart Fail Rev 2022 Jan;27(1):271-280. doi: 10.1007/s10741-020-09988-y. PMID: 32535741
Ventricular arrhythmias associated with left ventricular noncompaction: Electrophysiologic characteristics, mapping, and ablation.
Muser D, Liang JJ, Witschey WR, Pathak RK, Castro S, Magnani S, Zado ES, Garcia FC, Desjardins B, Callans DJ, Frankel DS, Marchlinski FE, Santangeli P
Heart Rhythm 2017 Feb;14(2):166-175. Epub 2016 Nov 24 doi: 10.1016/j.hrthm.2016.11.014. PMID: 27890738
Contractile Dysfunction in Sarcomeric Hypertrophic Cardiomyopathy.
MacIver DH, Clark AL
J Card Fail 2016 Sep;22(9):731-7. Epub 2016 May 16 doi: 10.1016/j.cardfail.2016.03.020. PMID: 27090746
Noninvasive Multimodality Imaging in ARVD/C.
Te Riele ASJM, Tandri H, Sanborn DM, Bluemke DA
JACC Cardiovasc Imaging 2015 May;8(5):597-611. doi: 10.1016/j.jcmg.2015.02.007. PMID: 25937197Free PMC Article
Physiology of biventricular pacing.
Bilchick KC, Helm RH, Kass DA
Curr Cardiol Rep 2007 Sep;9(5):358-65. doi: 10.1007/BF02938362. PMID: 17877930

Clinical prediction guides

Parametric Imaging for the Assessment of Cardiac Motion: A Review.
Benameur N, Caiani EG, Arous Y, Ben Abdallah N, Kraiem T
Cardiovasc Eng Technol 2018 Sep;9(3):377-393. Epub 2018 May 14 doi: 10.1007/s13239-018-0362-1. PMID: 29761408
Hemodialysis-induced regional left ventricular systolic dysfunction.
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507
Noninvasive Multimodality Imaging in ARVD/C.
Te Riele ASJM, Tandri H, Sanborn DM, Bluemke DA
JACC Cardiovasc Imaging 2015 May;8(5):597-611. doi: 10.1016/j.jcmg.2015.02.007. PMID: 25937197Free PMC Article
Physiology of biventricular pacing.
Bilchick KC, Helm RH, Kass DA
Curr Cardiol Rep 2007 Sep;9(5):358-65. doi: 10.1007/BF02938362. PMID: 17877930
Echocardiography in ischemic heart disease.
Corya BC
Am J Med 1977 Jul;63(1):10-20. doi: 10.1016/0002-9343(77)90113-9. PMID: 327801

Recent systematic reviews

A systematic review on focal takotsubo syndrome: a not-so-small matter.
Tini G, Limite LR, Arcari L, Cacciotti L, Russo D, Sclafani M, Brunelli C, Volpe M, Autore C, Musumeci MB
Heart Fail Rev 2022 Jan;27(1):271-280. doi: 10.1007/s10741-020-09988-y. PMID: 32535741

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