U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Refractory B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

MedGen UID:
1626003
•Concept ID:
C4525407
•
Neoplastic Process
Synonyms: Refractory B Acute Lymphoblastic Leukemia with BCR-ABL1-Like Features; Refractory B Acute Lymphoblastic Leukemia, BCR::ABL1-Like; Refractory B-Acute Lymphoblastic Leukemia with BCR::ABL1-Like Features; Refractory B-Acute Lymphoblastic Leukemia, BCR::ABL1-Like; Refractory Ph-Like Acute Lymphoblastic Leukemia

Definition

B-acute lymphoblastic leukemia, BCR-ABL1-like that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

Recent clinical studies

Etiology

Have any strategies in Ph-like ALL been shown to be effective?
Aldoss I, Advani AS
Best Pract Res Clin Haematol 2021 Mar;34(1):101242. Epub 2021 Jan 11 doi: 10.1016/j.beha.2021.101242. PMID: 33762097

Diagnosis

Have any strategies in Ph-like ALL been shown to be effective?
Aldoss I, Advani AS
Best Pract Res Clin Haematol 2021 Mar;34(1):101242. Epub 2021 Jan 11 doi: 10.1016/j.beha.2021.101242. PMID: 33762097
Identification of RNPC3 as a novel JAK2 fusion partner gene in B-acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib.
Chen X, Wang F, Zhang Y, Ma X, Liu M, Cao P, Zhou L, Wang L, Zhang X, Wang T, Liu H
Mol Genet Genomic Med 2020 Mar;8(3):e1110. Epub 2019 Dec 30 doi: 10.1002/mgg3.1110. PMID: 31885183Free PMC Article

Therapy

Identification of RNPC3 as a novel JAK2 fusion partner gene in B-acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib.
Chen X, Wang F, Zhang Y, Ma X, Liu M, Cao P, Zhou L, Wang L, Zhang X, Wang T, Liu H
Mol Genet Genomic Med 2020 Mar;8(3):e1110. Epub 2019 Dec 30 doi: 10.1002/mgg3.1110. PMID: 31885183Free PMC Article

Prognosis

Identification of RNPC3 as a novel JAK2 fusion partner gene in B-acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib.
Chen X, Wang F, Zhang Y, Ma X, Liu M, Cao P, Zhou L, Wang L, Zhang X, Wang T, Liu H
Mol Genet Genomic Med 2020 Mar;8(3):e1110. Epub 2019 Dec 30 doi: 10.1002/mgg3.1110. PMID: 31885183Free PMC Article

Clinical prediction guides

Have any strategies in Ph-like ALL been shown to be effective?
Aldoss I, Advani AS
Best Pract Res Clin Haematol 2021 Mar;34(1):101242. Epub 2021 Jan 11 doi: 10.1016/j.beha.2021.101242. PMID: 33762097

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...