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Striatal T2 hyperintensity

MedGen UID:
1626830
Concept ID:
C4531279
Finding
HPO: HP:0031206

Definition

Abnormally bright T2 signal from the striatum on brain magnetic resonance imaging. [from HPO]

Term Hierarchy

Conditions with this feature

Striatonigral degeneration, infantile, mitochondrial
MedGen UID:
374113
Concept ID:
C1839022
Disease or Syndrome

Professional guidelines

PubMed

Arnold G, Tatsch K, Oertel WH, Vogl T, Schwarz J, Kraft E, Kirsch CM
J Neural Transm Suppl 1994;42:111-8. doi: 10.1007/978-3-7091-6641-3_9. PMID: 7964681

Recent clinical studies

Etiology

Carrer T, Bonato G, Sandre M, Emmi A, Campagnolo M, Musso G, Carecchio M, Parchi P, Antonini A
Neurol Sci 2024 Jan;45(1):309-313. Epub 2023 Sep 27 doi: 10.1007/s10072-023-07056-5. PMID: 37752324
Baide-Mairena H, Marti-Sánchez L, Marcé-Grau A, Cazurro-Gutiérrez A, Sanchez-Montanez A, Delgado I, Moreno-Galdó A, Macaya-Ruiz A, García-Arumí E, Pérez-Dueñas B; Childhood Basal Ganglia Disease Group
Dev Med Child Neurol 2022 Jun;64(6):743-752. Epub 2022 Jan 5 doi: 10.1111/dmcn.15125. PMID: 34988976
Benjamin P, Sudhakar S, D'Arco F, Löbel U, Carney O, Roux CJ, Boddaert N, Hemingway C, Eleftheriou D, Mankad K
AJNR Am J Neuroradiol 2022 Jan;43(1):2-10. Epub 2021 Dec 23 doi: 10.3174/ajnr.A7362. PMID: 34949589Free PMC Article
Yu F, Steven A, Birnbaum L, Altmeyer W
J Neuroradiol 2017 Feb;44(1):24-30. Epub 2016 Nov 9 doi: 10.1016/j.neurad.2016.09.005. PMID: 27836650
Yeh PH, Guan Koay C, Wang B, Morissette J, Sham E, Senseney J, Joy D, Kubli A, Yeh CH, Eskay V, Liu W, French LM, Oakes TR, Riedy G, Ollinger J
Hum Brain Mapp 2017 Jan;38(1):352-369. Epub 2016 Sep 15 doi: 10.1002/hbm.23365. PMID: 27629984Free PMC Article

Diagnosis

Carrer T, Bonato G, Sandre M, Emmi A, Campagnolo M, Musso G, Carecchio M, Parchi P, Antonini A
Neurol Sci 2024 Jan;45(1):309-313. Epub 2023 Sep 27 doi: 10.1007/s10072-023-07056-5. PMID: 37752324
Baide-Mairena H, Marti-Sánchez L, Marcé-Grau A, Cazurro-Gutiérrez A, Sanchez-Montanez A, Delgado I, Moreno-Galdó A, Macaya-Ruiz A, García-Arumí E, Pérez-Dueñas B; Childhood Basal Ganglia Disease Group
Dev Med Child Neurol 2022 Jun;64(6):743-752. Epub 2022 Jan 5 doi: 10.1111/dmcn.15125. PMID: 34988976
Benjamin P, Sudhakar S, D'Arco F, Löbel U, Carney O, Roux CJ, Boddaert N, Hemingway C, Eleftheriou D, Mankad K
AJNR Am J Neuroradiol 2022 Jan;43(1):2-10. Epub 2021 Dec 23 doi: 10.3174/ajnr.A7362. PMID: 34949589Free PMC Article
Ntorkou AA, Daire J, Renaldo F, Doummar D, Alison M, Schiff M, Elmaleh-Bergès M
AJNR Am J Neuroradiol 2021 Sep;42(9):1722-1726. Epub 2021 Jul 8 doi: 10.3174/ajnr.A7199. PMID: 34244130Free PMC Article
Harting I, Al-Saady M, Krägeloh-Mann I, Bley A, Hempel M, Bierhals T, Karch S, Moog U, Bernard G, Huntsman R, van Spaendonk RML, Vreeburg M, Rodríguez-Palmero A, Pujol A, van der Knaap MS, Pouwels PJW, Wolf NI
Neurogenetics 2020 Apr;21(2):121-133. Epub 2020 Jan 15 doi: 10.1007/s10048-019-00602-4. PMID: 31940116Free PMC Article

Therapy

Oommen AT, Polavarapu K, Christopher R, Netravathi M
Neurol India 2022 Mar-Apr;70(2):733-736. doi: 10.4103/0028-3886.344659. PMID: 35532649
Watts C, Donovan T, Gillard JH, Antoun NM, Burnstein R, Menon DK, Carpenter TA, Fryer T, Thomas DG, Pickard JD
Cell Transplant 2003;12(7):697-704. doi: 10.3727/000000003108747316. PMID: 14653617
Yamada H, Momose T, Okada M, Kuroiwa Y
J Neurol Neurosurg Psychiatry 2002 Jan;72(1):111-3. doi: 10.1136/jnnp.72.1.111. PMID: 11784836Free PMC Article
Yamamoto K, Chiba HO, Ishitobi M, Nakagawa H, Ogawa T, Ishii K
Eur J Paediatr Neurol 1997;1(1):41-5. doi: 10.1016/s1090-3798(97)80010-4. PMID: 10728192
Fujita K, Takeuchi Y, Nishimura A, Takada H, Sawada T
Pediatr Neurol 1994 Mar;10(2):157-60. doi: 10.1016/0887-8994(94)90050-7. PMID: 8024666

Prognosis

Carrer T, Bonato G, Sandre M, Emmi A, Campagnolo M, Musso G, Carecchio M, Parchi P, Antonini A
Neurol Sci 2024 Jan;45(1):309-313. Epub 2023 Sep 27 doi: 10.1007/s10072-023-07056-5. PMID: 37752324
Ohe Y, Uchino A, Horiuchi Y, Maruyama H, Deguchi I, Fukuoka T, Kato Y, Nagoya H, Dembo T, Tanahashi N
J Stroke Cerebrovasc Dis 2013 Jan;22(1):58-65. Epub 2011 Jul 23 doi: 10.1016/j.jstrokecerebrovasdis.2011.06.006. PMID: 21784662
Bohnen NI, Müller ML, Zarzhevsky N, Koeppe RA, Bogan CW, Kilbourn MR, Frey KA, Albin RL
Brain 2011 Aug;134(Pt 8):2358-65. Epub 2011 Jun 8 doi: 10.1093/brain/awr139. PMID: 21653540Free PMC Article
Sinha S, Taly AB, Ravishankar S, Prashanth LK, Venugopal KS, Arunodaya GR, Vasudev MK, Swamy HS
Neuroradiology 2006 Sep;48(9):613-21. Epub 2006 Jun 3 doi: 10.1007/s00234-006-0101-4. PMID: 16752136
Lin JJ, Lin GY, Shih C, Shen WC
J Neurol 2001 Sep;248(9):750-5. doi: 10.1007/s004150170089. PMID: 11596778

Clinical prediction guides

Baide-Mairena H, Marti-Sánchez L, Marcé-Grau A, Cazurro-Gutiérrez A, Sanchez-Montanez A, Delgado I, Moreno-Galdó A, Macaya-Ruiz A, García-Arumí E, Pérez-Dueñas B; Childhood Basal Ganglia Disease Group
Dev Med Child Neurol 2022 Jun;64(6):743-752. Epub 2022 Jan 5 doi: 10.1111/dmcn.15125. PMID: 34988976
Ntorkou AA, Daire J, Renaldo F, Doummar D, Alison M, Schiff M, Elmaleh-Bergès M
AJNR Am J Neuroradiol 2021 Sep;42(9):1722-1726. Epub 2021 Jul 8 doi: 10.3174/ajnr.A7199. PMID: 34244130Free PMC Article
Yeh PH, Guan Koay C, Wang B, Morissette J, Sham E, Senseney J, Joy D, Kubli A, Yeh CH, Eskay V, Liu W, French LM, Oakes TR, Riedy G, Ollinger J
Hum Brain Mapp 2017 Jan;38(1):352-369. Epub 2016 Sep 15 doi: 10.1002/hbm.23365. PMID: 27629984Free PMC Article
Bohnen NI, Müller ML, Zarzhevsky N, Koeppe RA, Bogan CW, Kilbourn MR, Frey KA, Albin RL
Brain 2011 Aug;134(Pt 8):2358-65. Epub 2011 Jun 8 doi: 10.1093/brain/awr139. PMID: 21653540Free PMC Article
Oliva D, Carella F, Savoiardo M, Strada L, Giovannini P, Testa D, Filippini G, Caraceni T, Girotti F
Arch Neurol 1993 Jan;50(1):17-9. doi: 10.1001/archneur.1993.00540010013010. PMID: 8418795

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