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Recurrent Childhood Malignant Solid Neoplasm

MedGen UID:
1638936
•Concept ID:
C4688333
•
Neoplastic Process
Synonyms: Childhood Recurrent Malignant Solid Neoplasm; Childhood Recurrent Malignant Solid Tumor

Definition

The reemergence of a childhood malignant solid neoplasm after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Malignant Solid Neoplasm

Professional guidelines

PubMed

Oncolytic virotherapy for the treatment of pediatric brainstem gliomas.
Gállego Pérez-Larraya J, García-Moure M, Alonso MM
Rev Neurol (Paris) 2023 Jun;179(5):475-480. Epub 2023 Apr 13 doi: 10.1016/j.neurol.2023.03.016. PMID: 37061388
Advances in emerging drugs for the treatment of neuroblastoma.
Berlanga P, Cañete A, Castel V
Expert Opin Emerg Drugs 2017 Mar;22(1):63-75. Epub 2017 Feb 22 doi: 10.1080/14728214.2017.1294159. PMID: 28253830
MIBG scintigraphy for the diagnosis and follow-up of children with neuroblastoma.
Boubaker A, Bischof Delaloye A
Q J Nucl Med Mol Imaging 2008 Dec;52(4):388-402. PMID: 19088693

Recent clinical studies

Etiology

A Phase I/II Trial of Nivolumab plus Ipilimumab in Children and Young Adults with Relapsed/Refractory Solid Tumors: A Children's Oncology Group Study ADVL1412.
Davis KL, Fox E, Isikwei E, Reid JM, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Clin Cancer Res 2022 Dec 1;28(23):5088-5097. doi: 10.1158/1078-0432.CCR-22-2164. PMID: 36190525Free PMC Article
How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?
Akter J, Kamijo T
Biomolecules 2021 Jul 28;11(8) doi: 10.3390/biom11081112. PMID: 34439779Free PMC Article
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Chlorambucil-induced seizures.
Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164
Wilms tumor.
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525

Diagnosis

Oncolytic virotherapy for the treatment of pediatric brainstem gliomas.
Gállego Pérez-Larraya J, García-Moure M, Alonso MM
Rev Neurol (Paris) 2023 Jun;179(5):475-480. Epub 2023 Apr 13 doi: 10.1016/j.neurol.2023.03.016. PMID: 37061388
Adult pancreatoblastoma: Current concepts in pathology.
Omiyale AO
World J Gastroenterol 2021 Jul 14;27(26):4172-4181. doi: 10.3748/wjg.v27.i26.4172. PMID: 34326617Free PMC Article
Y-Box Binding Protein-1: A Neglected Target in Pediatric Brain Tumors?
Taylor L, Kerr ID, Coyle B
Mol Cancer Res 2021 Mar;19(3):375-387. Epub 2020 Nov 25 doi: 10.1158/1541-7786.MCR-20-0655. PMID: 33239357
Childhood brain tumors.
Sklar CA
J Pediatr Endocrinol Metab 2002 May;15 Suppl 2:669-73. doi: 10.1515/jpem.2002.15.s2.669. PMID: 12092679
Chlorambucil-induced seizures.
Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

Therapy

Oncolytic virotherapy for the treatment of pediatric brainstem gliomas.
Gállego Pérez-Larraya J, García-Moure M, Alonso MM
Rev Neurol (Paris) 2023 Jun;179(5):475-480. Epub 2023 Apr 13 doi: 10.1016/j.neurol.2023.03.016. PMID: 37061388
A Phase I/II Trial of Nivolumab plus Ipilimumab in Children and Young Adults with Relapsed/Refractory Solid Tumors: A Children's Oncology Group Study ADVL1412.
Davis KL, Fox E, Isikwei E, Reid JM, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Clin Cancer Res 2022 Dec 1;28(23):5088-5097. doi: 10.1158/1078-0432.CCR-22-2164. PMID: 36190525Free PMC Article
How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?
Akter J, Kamijo T
Biomolecules 2021 Jul 28;11(8) doi: 10.3390/biom11081112. PMID: 34439779Free PMC Article
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Chlorambucil-induced seizures.
Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

Prognosis

Oncolytic virotherapy for the treatment of pediatric brainstem gliomas.
Gállego Pérez-Larraya J, García-Moure M, Alonso MM
Rev Neurol (Paris) 2023 Jun;179(5):475-480. Epub 2023 Apr 13 doi: 10.1016/j.neurol.2023.03.016. PMID: 37061388
Advances in emerging drugs for the treatment of neuroblastoma.
Berlanga P, Cañete A, Castel V
Expert Opin Emerg Drugs 2017 Mar;22(1):63-75. Epub 2017 Feb 22 doi: 10.1080/14728214.2017.1294159. PMID: 28253830
Neuroblastoma: biology, prognosis, and treatment.
Park JR, Eggert A, Caron H
Hematol Oncol Clin North Am 2010 Feb;24(1):65-86. doi: 10.1016/j.hoc.2009.11.011. PMID: 20113896
Neuroblastoma: biology, prognosis, and treatment.
Park JR, Eggert A, Caron H
Pediatr Clin North Am 2008 Feb;55(1):97-120, x. doi: 10.1016/j.pcl.2007.10.014. PMID: 18242317
Wilms tumor.
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525

Clinical prediction guides

A Phase I/II Trial of Nivolumab plus Ipilimumab in Children and Young Adults with Relapsed/Refractory Solid Tumors: A Children's Oncology Group Study ADVL1412.
Davis KL, Fox E, Isikwei E, Reid JM, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Clin Cancer Res 2022 Dec 1;28(23):5088-5097. doi: 10.1158/1078-0432.CCR-22-2164. PMID: 36190525Free PMC Article
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Advances in emerging drugs for the treatment of neuroblastoma.
Berlanga P, Cañete A, Castel V
Expert Opin Emerg Drugs 2017 Mar;22(1):63-75. Epub 2017 Feb 22 doi: 10.1080/14728214.2017.1294159. PMID: 28253830
Childhood brain tumors.
Sklar CA
J Pediatr Endocrinol Metab 2002 May;15 Suppl 2:669-73. doi: 10.1515/jpem.2002.15.s2.669. PMID: 12092679
Chlorambucil-induced seizures.
Salloum E, Khan KK, Cooper DL
Cancer 1997 Mar 1;79(5):1009-13. doi: 10.1002/(sici)1097-0142(19970301)79:5<1009::aid-cncr18>3.0.co;2-5. PMID: 9041164

Recent systematic reviews

A systematic review of evidence for and against routine surveillance imaging after completing treatment for childhood extracranial solid tumors.
Morgan JE, Walker R, Harden M, Phillips RS
Cancer Med 2020 Jul;9(14):4949-4961. Epub 2020 May 19 doi: 10.1002/cam4.3110. PMID: 32431088Free PMC Article
Solid Pseudopapillary Neoplasm of the Pancreas in a Young Pediatric Patient: A Case Report and Systematic Review of the Literature.
Bender AM, Thompson ED, Hackam DJ, Cameron JL, Rhee DS
Pancreas 2018 Nov/Dec;47(10):1364-1368. doi: 10.1097/MPA.0000000000001183. PMID: 30325866
Solid pseudopapillary and malignant pancreatic tumors in childhood: A systematic review and evidence quality assessment.
Mylonas KS, Doulamis IP, Tsilimigras DI, Nasioudis D, Schizas D, Masiakos PT, Kelleher CM
Pediatr Blood Cancer 2018 Oct;65(10):e27114. Epub 2018 Apr 26 doi: 10.1002/pbc.27114. PMID: 29697193
123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma.
Bleeker G, Tytgat GA, Adam JA, Caron HN, Kremer LC, Hooft L, van Dalen EC
Cochrane Database Syst Rev 2015 Sep 29;2015(9):CD009263. doi: 10.1002/14651858.CD009263.pub2. PMID: 26417712Free PMC Article

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