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Abnormal ascending aorta morphology

MedGen UID:
1645394
•Concept ID:
C4703539
•
Anatomical Abnormality
HPO: HP:0031784

Definition

Any structural anomaly of the portion of the aorta that arises from the base of the left ventricle and extends upward to the aortic arch and from which the coronary arteries arise. [from HPO]

Professional guidelines

PubMed

Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review.
Gaudino M, Di Franco A, Arbustini E, Bacha E, Bates ER, Cameron DE, Cao D, David TE, De Paulis R, El-Hamamsy I, Farooqi KM, Girardi LN, Gräni C, Kochav JD, Molossi S, Puskas JD, Rao SV, Sandner S, Tatoulis J, Truong QA, Weinsaft JW, Zimpfer D, Mery CM
J Am Coll Cardiol 2023 Nov 21;82(21):2034-2053. Epub 2023 Oct 16 doi: 10.1016/j.jacc.2023.08.012. PMID: 37855757
International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Diagnostic and Treatment Dilemmas of the Aortic Arch.
Hui DS, Fleischman F
Cardiol Clin 2017 Aug;35(3):347-355. doi: 10.1016/j.ccl.2017.03.012. PMID: 28683906

Recent clinical studies

Etiology

Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review.
Gaudino M, Di Franco A, Arbustini E, Bacha E, Bates ER, Cameron DE, Cao D, David TE, De Paulis R, El-Hamamsy I, Farooqi KM, Girardi LN, Gräni C, Kochav JD, Molossi S, Puskas JD, Rao SV, Sandner S, Tatoulis J, Truong QA, Weinsaft JW, Zimpfer D, Mery CM
J Am Coll Cardiol 2023 Nov 21;82(21):2034-2053. Epub 2023 Oct 16 doi: 10.1016/j.jacc.2023.08.012. PMID: 37855757
Native aorto-ostial coronary lesions on CT coronary angiogram.
Riley JYJ, Leong K, Mortensen KH, Ariff B, Gopalan D
Br J Radiol 2021 Jul 1;94(1123):20210211. Epub 2021 Jun 9 doi: 10.1259/bjr.20210211. PMID: 33989055Free PMC Article
The aberrant subclavian artery: approach to management.
Karangelis D, Loggos S, Tzifa A, Mitropoulos FA
Curr Opin Cardiol 2020 Nov;35(6):636-642. doi: 10.1097/HCO.0000000000000793. PMID: 32852349
Preoperative Physiology, Imaging, and Management of Interrupted Aortic Arch.
Friedman K
Semin Cardiothorac Vasc Anesth 2018 Sep;22(3):265-269. Epub 2018 Apr 12 doi: 10.1177/1089253218770198. PMID: 29649938
Introduction to anomalous aortic origin of a coronary artery.
Brothers JA
Congenit Heart Dis 2017 Sep;12(5):600-602. Epub 2017 Jun 27 doi: 10.1111/chd.12497. PMID: 28653465

Diagnosis

Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review.
Gaudino M, Di Franco A, Arbustini E, Bacha E, Bates ER, Cameron DE, Cao D, David TE, De Paulis R, El-Hamamsy I, Farooqi KM, Girardi LN, Gräni C, Kochav JD, Molossi S, Puskas JD, Rao SV, Sandner S, Tatoulis J, Truong QA, Weinsaft JW, Zimpfer D, Mery CM
J Am Coll Cardiol 2023 Nov 21;82(21):2034-2053. Epub 2023 Oct 16 doi: 10.1016/j.jacc.2023.08.012. PMID: 37855757
Preoperative Physiology, Imaging, and Management of Interrupted Aortic Arch.
Friedman K
Semin Cardiothorac Vasc Anesth 2018 Sep;22(3):265-269. Epub 2018 Apr 12 doi: 10.1177/1089253218770198. PMID: 29649938
Rings and slings revisited.
Smith BM, Lu JC, Dorfman AL, Mahani MG, Agarwal PP
Magn Reson Imaging Clin N Am 2015 Feb;23(1):127-35. Epub 2014 Oct 3 doi: 10.1016/j.mric.2014.09.011. PMID: 25476681
Aortic arch malformations.
Kellenberger CJ
Pediatr Radiol 2010 Jun;40(6):876-84. Epub 2010 Mar 31 doi: 10.1007/s00247-010-1607-9. PMID: 20354848
Aortic arch anomalies.
Weinberg PM
J Cardiovasc Magn Reson 2006;8(4):633-43. doi: 10.1080/10976640600713756. PMID: 16869315

Therapy

Management of bicuspid aortic valve disease in the transcatheter aortic valve implantation era.
Jahangiri M, Prendergast B
Heart 2024 Oct 28;110(22):1291-1297. doi: 10.1136/heartjnl-2024-324054. PMID: 39117383
The aberrant subclavian artery: approach to management.
Karangelis D, Loggos S, Tzifa A, Mitropoulos FA
Curr Opin Cardiol 2020 Nov;35(6):636-642. doi: 10.1097/HCO.0000000000000793. PMID: 32852349
Editor's Choice - Management of Descending Thoracic Aorta Diseases: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS).
Riambau V, Böckler D, Brunkwall J, Cao P, Chiesa R, Coppi G, Czerny M, Fraedrich G, Haulon S, Jacobs MJ, Lachat ML, Moll FL, Setacci C, Taylor PR, Thompson M, Trimarchi S, Verhagen HJ, Verhoeven EL, Esvs Guidelines Committee, Kolh P, de Borst GJ, Chakfé N, Debus ES, Hinchliffe RJ, Kakkos S, Koncar I, Lindholt JS, Vega de Ceniga M, Vermassen F, Verzini F, Document Reviewers, Kolh P, Black JH 3rd, Busund R, Björck M, Dake M, Dick F, Eggebrecht H, Evangelista A, Grabenwöger M, Milner R, Naylor AR, Ricco JB, Rousseau H, Schmidli J
Eur J Vasc Endovasc Surg 2017 Jan;53(1):4-52. doi: 10.1016/j.ejvs.2016.06.005. PMID: 28081802
Proximate cause.
Berlin L
AJR Am J Roentgenol 2002 Sep;179(3):569-73. doi: 10.2214/ajr.179.3.1790569. PMID: 12185020
The "skinny aorta".
Israel G, Krinsky G, Lee V
Clin Imaging 2002 Mar-Apr;26(2):116-21. doi: 10.1016/s0899-7071(01)00368-0. PMID: 11852219

Prognosis

Introduction to anomalous aortic origin of a coronary artery.
Brothers JA
Congenit Heart Dis 2017 Sep;12(5):600-602. Epub 2017 Jun 27 doi: 10.1111/chd.12497. PMID: 28653465
Decision making in anomalous aortic origin of a coronary artery.
Mery CM
Congenit Heart Dis 2017 Sep;12(5):630-632. Epub 2017 Jun 9 doi: 10.1111/chd.12493. PMID: 28598033
Imaging of congenital anomalies of the coronary arteries.
Raimondi F, Bonnet D
Diagn Interv Imaging 2016 May;97(5):561-9. Epub 2016 Apr 26 doi: 10.1016/j.diii.2016.03.009. PMID: 27132711
An Overview of Pulmonary Atresia and Major Aortopulmonary Collateral Arteries.
Presnell LB, Blankenship A, Cheatham SL, Owens GE, Staveski SL
World J Pediatr Congenit Heart Surg 2015 Oct;6(4):630-9. doi: 10.1177/2150135115598559. PMID: 26467877
Aortico-left ventricular tunnel.
Ruschewski W, de Vivie ER, Kirchhoff PG
Thorac Cardiovasc Surg 1981 Oct;29(5):282-6. doi: 10.1055/s-2007-1023496. PMID: 6179201

Clinical prediction guides

Contemporary Multicenter Outcomes for Truncus Arteriosus With Interrupted Aortic Arch.
Buckley JR, Costello JM, Smerling AJ, Sassalos P, Amula V, Cashen K, Riley CM, Bakar AM, Iliopoulos I, Jennings A, Narasimhulu SS, Mastropietro CW; Collaborative Research from the Pediatric Cardiac Intensive Care Society Investigators
Ann Thorac Surg 2023 Jan;115(1):144-150. Epub 2022 Sep 6 doi: 10.1016/j.athoracsur.2022.08.040. PMID: 36084696
Morphology of vascular ring arch anomalies influences prognosis and management.
Ctori E, Crucean A, Pinkey B, McGuirk SP, Anderson RH, Stickley J, Jones TJ, Seale AN
Arch Dis Child 2021 Apr 21;106(5):477-483. doi: 10.1136/archdischild-2020-319388. PMID: 33106229
How Small Is Too Small? Decision-Making and Management of the Small Aortic Root in the Setting of Interrupted Aortic Arch.
Riggs KW, Tweddell JS
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2019;22:21-26. doi: 10.1053/j.pcsu.2019.02.004. PMID: 31027560
Numerical investigation of mass transport through patient-specific deformed aortae.
Chen J, Gutmark E, Mylavarapu G, Backeljauw PF, Gutmark-Little I
J Biomech 2014 Jan 22;47(2):544-52. Epub 2013 Oct 21 doi: 10.1016/j.jbiomech.2013.10.031. PMID: 24210472
Overview of MR of the heart--1986.
Higgins CB
AJR Am J Roentgenol 1986 May;146(5):907-18. doi: 10.2214/ajr.146.5.907. PMID: 3515882

Recent systematic reviews

Diagnostic accuracy of prenatal ultrasound in coarctation of aorta: systematic review and individual participant data meta-analysis.
Villalaín C, D'Antonio F, Flacco ME, Gómez-Montes E, Herraiz I, Deiros-Bronte L, Maskatia SA, Phillips AA, Contro E, Fricke K, Bhawna A, Beattie MJ, Moon-Grady AJ, Durand I, Slodki M, Respondek-Liberska M, Patel C, Kawamura H, Rizzo G, Pagani G, Galindo A
Ultrasound Obstet Gynecol 2024 Apr;63(4):446-456. Epub 2024 Mar 9 doi: 10.1002/uog.27576. PMID: 38197327
Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review.
Gaudino M, Di Franco A, Arbustini E, Bacha E, Bates ER, Cameron DE, Cao D, David TE, De Paulis R, El-Hamamsy I, Farooqi KM, Girardi LN, Gräni C, Kochav JD, Molossi S, Puskas JD, Rao SV, Sandner S, Tatoulis J, Truong QA, Weinsaft JW, Zimpfer D, Mery CM
J Am Coll Cardiol 2023 Nov 21;82(21):2034-2053. Epub 2023 Oct 16 doi: 10.1016/j.jacc.2023.08.012. PMID: 37855757
Type III Arch Configuration as a Risk Factor for Carotid Artery Stenting: A Systematic Review of Contemporary Guidelines on Management of Carotid Artery Stenosis.
Marrocco-Trischitta MM, Baroni I, Vitale R, Nava G, Nano G, Secchi F
Ann Vasc Surg 2020 Oct;68:505-509. Epub 2020 Apr 25 doi: 10.1016/j.avsg.2020.04.019. PMID: 32339684
Bicuspid aortic valve morphology and its impact on aortic diameters-A systematic review with meta-analysis and meta-regression.
Miśkowiec D, Lipiec P, Szymczyk E, Wejner-Mik P, Michalski B, Kupczyńska K, Wierzbowska-Drabik K, Kasprzak JD
Echocardiography 2018 May;35(5):667-677. Epub 2018 Feb 4 doi: 10.1111/echo.13818. PMID: 29399873
Bicuspid aortic valve aortopathy: genetics, pathophysiology and medical therapy.
Abdulkareem N, Smelt J, Jahangiri M
Interact Cardiovasc Thorac Surg 2013 Sep;17(3):554-9. Epub 2013 May 31 doi: 10.1093/icvts/ivt196. PMID: 23728086Free PMC Article

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