U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal morphology of the great vessels

MedGen UID:
1375454
Concept ID:
C4476878
Anatomical Abnormality
HPO: HP:0030962

Definition

A structural anomaly affecting a blood vessel involved in the circulation of the heart, i.e., the superior or inferior vena cava, the pulmonary arteries, the pulmonary veins, and the aorta. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal morphology of the great vessels

Professional guidelines

PubMed

ElKiran YM, Abdelgawwad MS, Abdelmaksoud MA, Elwakeel HA, Elshafei AM
World Neurosurg 2021 Jun;150:e756-e764. Epub 2021 Apr 2 doi: 10.1016/j.wneu.2021.03.140. PMID: 33819709
Kamran A, Baird CW, Jennings RW
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020;23:53-61. doi: 10.1053/j.pcsu.2020.02.006. PMID: 32354548
Ollauri-Ibáñez C, López-Novoa JM, Pericacho M
Expert Opin Biol Ther 2017 Sep;17(9):1053-1063. Epub 2017 Jul 10 doi: 10.1080/14712598.2017.1346607. PMID: 28656781

Recent clinical studies

Etiology

Riley JYJ, Leong K, Mortensen KH, Ariff B, Gopalan D
Br J Radiol 2021 Jul 1;94(1123):20210211. Epub 2021 Jun 9 doi: 10.1259/bjr.20210211. PMID: 33989055Free PMC Article
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Kutty S, Danford DA, Diller GP, Tutarel O
Heart 2018 Jul;104(14):1148-1155. Epub 2018 Jan 11 doi: 10.1136/heartjnl-2016-311032. PMID: 29326110
Squarcia U, Macchi C
Curr Opin Pediatr 2011 Oct;23(5):518-22. doi: 10.1097/MOP.0b013e32834aa551. PMID: 21849902
D'Andrea V, Malinovsky L, Cavallotti C, Benedetti Valentini F, Malinovska V, Bartolo M, Todini AR, Biancari F, Di Matteo FM, De Antoni E
J Cardiovasc Surg (Torino) 1997 Oct;38(5):447-55. PMID: 9358801

Diagnosis

Riley JYJ, Leong K, Mortensen KH, Ariff B, Gopalan D
Br J Radiol 2021 Jul 1;94(1123):20210211. Epub 2021 Jun 9 doi: 10.1259/bjr.20210211. PMID: 33989055Free PMC Article
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Kutty S, Danford DA, Diller GP, Tutarel O
Heart 2018 Jul;104(14):1148-1155. Epub 2018 Jan 11 doi: 10.1136/heartjnl-2016-311032. PMID: 29326110
Masiwal P, Chenthil KS, Priyadarsini B, Gnanaprakasam J, Srihari I
J Assoc Physicians India 2016 May;64(5):73-75. PMID: 27735157
D'Andrea V, Malinovsky L, Cavallotti C, Benedetti Valentini F, Malinovska V, Bartolo M, Todini AR, Biancari F, Di Matteo FM, De Antoni E
J Cardiovasc Surg (Torino) 1997 Oct;38(5):447-55. PMID: 9358801

Therapy

Padua MB, Helm BM, Wells JR, Smith AM, Bellchambers HM, Sridhar A, Ware SM
Hum Mol Genet 2023 Jul 4;32(14):2335-2346. doi: 10.1093/hmg/ddad065. PMID: 37158461Free PMC Article
Kutty S, Danford DA, Diller GP, Tutarel O
Heart 2018 Jul;104(14):1148-1155. Epub 2018 Jan 11 doi: 10.1136/heartjnl-2016-311032. PMID: 29326110
Ollauri-Ibáñez C, López-Novoa JM, Pericacho M
Expert Opin Biol Ther 2017 Sep;17(9):1053-1063. Epub 2017 Jul 10 doi: 10.1080/14712598.2017.1346607. PMID: 28656781
Wang Z, Dabrosin C, Yin X, Fuster MM, Arreola A, Rathmell WK, Generali D, Nagaraju GP, El-Rayes B, Ribatti D, Chen YC, Honoki K, Fujii H, Georgakilas AG, Nowsheen S, Amedei A, Niccolai E, Amin A, Ashraf SS, Helferich B, Yang X, Guha G, Bhakta D, Ciriolo MR, Aquilano K, Chen S, Halicka D, Mohammed SI, Azmi AS, Bilsland A, Keith WN, Jensen LD
Semin Cancer Biol 2015 Dec;35 Suppl(Suppl):S224-S243. Epub 2015 Jan 16 doi: 10.1016/j.semcancer.2015.01.001. PMID: 25600295Free PMC Article
Freundlich IM, Lind TA
CRC Crit Rev Clin Radiol Nucl Med 1975 Apr;6(2):171-216. PMID: 238789

Prognosis

Nigro B, Ayarragaray JEF
Ann Vasc Surg 2022 Feb;79:372-379. Epub 2021 Oct 10 doi: 10.1016/j.avsg.2021.07.029. PMID: 34644626
Malicki M, Marcinkowska W, Georgiev GP, Zielinska N, Olewnik Ł
Folia Morphol (Warsz) 2022;81(3):533-543. Epub 2021 Oct 5 doi: 10.5603/FM.a2021.0081. PMID: 34608985
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Rao R, Platt LD
Semin Perinatol 2016 Feb;40(1):67-78. Epub 2016 Jan 8 doi: 10.1053/j.semperi.2015.11.009. PMID: 26777687
Wallis GA, Debich-Spicer D, Anderson RH
Orphanet J Rare Dis 2011 May 14;6:22. doi: 10.1186/1750-1172-6-22. PMID: 21569592Free PMC Article

Clinical prediction guides

Nigro B, Ayarragaray JEF
Ann Vasc Surg 2022 Feb;79:372-379. Epub 2021 Oct 10 doi: 10.1016/j.avsg.2021.07.029. PMID: 34644626
Malicki M, Marcinkowska W, Georgiev GP, Zielinska N, Olewnik Ł
Folia Morphol (Warsz) 2022;81(3):533-543. Epub 2021 Oct 5 doi: 10.5603/FM.a2021.0081. PMID: 34608985
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Cilliers K, Page BJ
Turk Neurosurg 2016;26(5):653-61. doi: 10.5137/1019-5149.JTN.14294-15.1. PMID: 27337235
Fisher SJ
Am J Obstet Gynecol 2015 Oct;213(4 Suppl):S115-22. doi: 10.1016/j.ajog.2015.08.042. PMID: 26428489Free PMC Article

Recent systematic reviews

Guenther TM, Sherazee EA, Wisneski AD, Gustafson JD, Wozniak CJ, Raff GW
Ann Thorac Surg 2020 Sep;110(3):1063-1071. Epub 2020 Mar 7 doi: 10.1016/j.athoracsur.2020.01.082. PMID: 32156586
Cirocchi R, Henry BM, Rambotti M, Tomaszewski KA, Cappelli M, Vettorello G, Pistilli A, D'Andrea V, Amato B, Randolph J
J Vasc Surg Venous Lymphat Disord 2019 Jan;7(1):128-138.e7. Epub 2018 Nov 15 doi: 10.1016/j.jvsv.2018.06.006. PMID: 30448153
Ghi T, Dall'Asta A, Cavalli C, Galli L, Weiss A, Pedrazzi G, Kaihura CT, Volpe N, Agnetti A, Frusca T
J Matern Fetal Neonatal Med 2018 May;31(10):1350-1357. Epub 2017 Apr 20 doi: 10.1080/14767058.2017.1314459. PMID: 28366040
Wang Y, Tao Y
Orphanet J Rare Dis 2015 Jan 21;10:4. doi: 10.1186/s13023-015-0225-x. PMID: 25608574Free PMC Article
Kockaert M, de Roos KP, van Dijk L, Nijsten T, Neumann M
Dermatol Surg 2012 Jan;38(1):77-82. Epub 2011 Sep 14 doi: 10.1111/j.1524-4725.2011.02154.x. PMID: 22092751

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...