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Abnormal superoxide dismutase level

MedGen UID:
1646434
•Concept ID:
C4703565
•
Finding
Synonym: Abnormal superoxide:superoxide oxidoreductase activity
 
HPO: HP:0031835

Definition

An abnormal level of catalysis of the reaction [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal superoxide dismutase level

Professional guidelines

PubMed

Deciphering the role of metal and non-metals in the treatment of epilepsy.
Sande R, Doshi G, Godad A
Neurochem Int 2023 Jul;167:105536. Epub 2023 May 12 doi: 10.1016/j.neuint.2023.105536. PMID: 37178926
Metal Complexes or Chelators with ROS Regulation Capacity: Promising Candidates for Cancer Treatment.
Li X, Wang Y, Li M, Wang H, Dong X
Molecules 2021 Dec 27;27(1) doi: 10.3390/molecules27010148. PMID: 35011380Free PMC Article
Development of novel small molecules for the treatment of ALS.
Mathew B, Ruiz P, Pathak V, Suto MJ
Bioorg Med Chem Lett 2020 Feb 15;30(4):126950. Epub 2020 Jan 7 doi: 10.1016/j.bmcl.2020.126950. PMID: 31928838

Recent clinical studies

Etiology

The role of the mitochondrial trans-sulfuration in cerebro-cardio renal dysfunction during trisomy down syndrome.
Pushpakumar S, Singh M, Sen U, Tyagi N, Tyagi SC
Mol Cell Biochem 2024 Apr;479(4):825-829. Epub 2023 May 17 doi: 10.1007/s11010-023-04761-9. PMID: 37198322
Correlation between abnormal energy metabolism of ovarian granulosa cells and in vitro fertilization-embryo transfer outcomes in patients with polycystic ovary syndrome and obesity.
Zhao YK, Gao YN, Wang LC, Wang J, Wang GJ, Wu HL
J Ovarian Res 2023 Jul 21;16(1):145. doi: 10.1186/s13048-023-01204-3. PMID: 37480140Free PMC Article
Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis.
Song H, Jiang L, Yang W, Dai Y, Wang Y, Li Z, Liu P, Chen J
Biomed Pharmacother 2023 Sep;165:115105. Epub 2023 Jul 1 doi: 10.1016/j.biopha.2023.115105. PMID: 37399718
Melatonin and alcohol-related disorders.
Kurhaluk N, Tkachenko H
Chronobiol Int 2020 Jun;37(6):781-803. Epub 2020 May 18 doi: 10.1080/07420528.2020.1761372. PMID: 32419511
Role of copper in the process of spermatogenesis.
Ogórek M, Gąsior Ł, Pierzchała O, Daszkiewicz R, Lenartowicz M
Postepy Hig Med Dosw (Online) 2017 Aug 9;71(0):663-683. doi: 10.5604/01.3001.0010.3846. PMID: 28791960

Diagnosis

Identification and experimental validation of autophagy-related genes in abdominal aortic aneurysm.
Yuan X, Song Y, Xin H, Zhang L, Liu B, Ma J, Sun R, Guan X, Jiang Z
Eur J Med Res 2023 Sep 22;28(1):368. doi: 10.1186/s40001-023-01354-6. PMID: 37737183Free PMC Article
Deciphering the role of metal and non-metals in the treatment of epilepsy.
Sande R, Doshi G, Godad A
Neurochem Int 2023 Jul;167:105536. Epub 2023 May 12 doi: 10.1016/j.neuint.2023.105536. PMID: 37178926
Lipid-Based Molecules on Signaling Pathways in Autism Spectrum Disorder.
Yui K, Imataka G, Yoshihara S
Int J Mol Sci 2022 Aug 29;23(17) doi: 10.3390/ijms23179803. PMID: 36077195Free PMC Article
Relevant issues in the pathology and pathobiology of pulmonary hypertension.
Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D4-12. doi: 10.1016/j.jacc.2013.10.025. PMID: 24355640Free PMC Article
Down syndrome and beta-amyloid deposition.
Head E, Lott IT
Curr Opin Neurol 2004 Apr;17(2):95-100. doi: 10.1097/00019052-200404000-00003. PMID: 15021233

Therapy

Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis.
Song H, Jiang L, Yang W, Dai Y, Wang Y, Li Z, Liu P, Chen J
Biomed Pharmacother 2023 Sep;165:115105. Epub 2023 Jul 1 doi: 10.1016/j.biopha.2023.115105. PMID: 37399718
Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts.
Chen K, Liu Y, He J, Pavlos N, Wang C, Kenny J, Yuan J, Zhang Q, Xu J, He W
Int J Biol Sci 2020;16(11):1888-1900. Epub 2020 Apr 6 doi: 10.7150/ijbs.40917. PMID: 32398957Free PMC Article
Molecular Pathogenesis of Chewable Tobacco.
Baig S, Rubab Z, Farooq W
J Coll Physicians Surg Pak 2018 May;28(5):381-385. doi: 10.29271/jcpsp.2018.05.381. PMID: 29690969
Antioxidant therapeutics: Pandora's box.
Day BJ
Free Radic Biol Med 2014 Jan;66:58-64. Epub 2013 Jul 12 doi: 10.1016/j.freeradbiomed.2013.05.047. PMID: 23856377Free PMC Article
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J
Cell Metab 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. PMID: 22682224Free PMC Article

Prognosis

Identification and experimental validation of autophagy-related genes in abdominal aortic aneurysm.
Yuan X, Song Y, Xin H, Zhang L, Liu B, Ma J, Sun R, Guan X, Jiang Z
Eur J Med Res 2023 Sep 22;28(1):368. doi: 10.1186/s40001-023-01354-6. PMID: 37737183Free PMC Article
Deep neural network and molecular docking supported toxicity profile of prometryn.
Çakir F, Kutluer F, Yalçin E, Çavuşoğlu K, Acar A
Chemosphere 2023 Nov;340:139962. Epub 2023 Aug 24 doi: 10.1016/j.chemosphere.2023.139962. PMID: 37633608
A Review on Cellular and Molecular Mechanisms Linked to the Development of Diabetes Complications.
Babel RA, Dandekar MP
Curr Diabetes Rev 2021;17(4):457-473. doi: 10.2174/1573399816666201103143818. PMID: 33143626
Neuroprotective Effect of Antioxidants in the Brain.
Lee KH, Cha M, Lee BH
Int J Mol Sci 2020 Sep 28;21(19) doi: 10.3390/ijms21197152. PMID: 32998277Free PMC Article
Relevant issues in the pathology and pathobiology of pulmonary hypertension.
Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D4-12. doi: 10.1016/j.jacc.2013.10.025. PMID: 24355640Free PMC Article

Clinical prediction guides

Identification and experimental validation of autophagy-related genes in abdominal aortic aneurysm.
Yuan X, Song Y, Xin H, Zhang L, Liu B, Ma J, Sun R, Guan X, Jiang Z
Eur J Med Res 2023 Sep 22;28(1):368. doi: 10.1186/s40001-023-01354-6. PMID: 37737183Free PMC Article
Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis.
Song H, Jiang L, Yang W, Dai Y, Wang Y, Li Z, Liu P, Chen J
Biomed Pharmacother 2023 Sep;165:115105. Epub 2023 Jul 1 doi: 10.1016/j.biopha.2023.115105. PMID: 37399718
Neurofilament accumulations in amyotrophic lateral sclerosis patients' motor neurons impair axonal initial segment integrity.
Lefebvre-Omar C, Liu E, Dalle C, d'Incamps BL, Bigou S, Daube C, Karpf L, Davenne M, Robil N, Jost Mousseau C, Blanchard S, Tournaire G, Nicaise C, Salachas F, Lacomblez L, Seilhean D, Lobsiger CS, Millecamps S, Boillée S, Bohl D
Cell Mol Life Sci 2023 May 15;80(6):150. doi: 10.1007/s00018-023-04797-6. PMID: 37184603Free PMC Article
Deciphering the role of metal and non-metals in the treatment of epilepsy.
Sande R, Doshi G, Godad A
Neurochem Int 2023 Jul;167:105536. Epub 2023 May 12 doi: 10.1016/j.neuint.2023.105536. PMID: 37178926
Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts.
Chen K, Liu Y, He J, Pavlos N, Wang C, Kenny J, Yuan J, Zhang Q, Xu J, He W
Int J Biol Sci 2020;16(11):1888-1900. Epub 2020 Apr 6 doi: 10.7150/ijbs.40917. PMID: 32398957Free PMC Article

Recent systematic reviews

Oxidative Stress in the Early Stage of Psychosis.
Ventriglio A, Bellomo A, Donato F, Iris B, Giovanna V, Dario DS, Edwige C, Di Gioia Ilaria, Pettorruso M, Perna G, Valchera A, De Berardis D
Curr Top Med Chem 2021 Oct 25;21(16):1457-1470. doi: 10.2174/1568026621666210701105839. PMID: 34218786
Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis.
Murri M, Luque-Ramírez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF
Hum Reprod Update 2013 May-Jun;19(3):268-88. Epub 2013 Jan 9 doi: 10.1093/humupd/dms059. PMID: 23303572

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