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Abnormal enzyme concentration or activity

MedGen UID:
1841674
Concept ID:
C5826586
Finding
HPO: HP:0034684

Definition

Concentration or activity of an enzyme is above or below the limits of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal enzyme concentration or activity

Professional guidelines

PubMed

Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Succoio M, Sacchettini R, Rossi A, Parenti G, Ruoppolo M
Biomolecules 2022 Jul 11;12(7) doi: 10.3390/biom12070968. PMID: 35883524Free PMC Article
Menopause 2021 Sep 1;28(9):973-997. doi: 10.1097/GME.0000000000001831. PMID: 34448749

Recent clinical studies

Etiology

Billinger SA, Arena R, Bernhardt J, Eng JJ, Franklin BA, Johnson CM, MacKay-Lyons M, Macko RF, Mead GE, Roth EJ, Shaughnessy M, Tang A; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Lifestyle and Cardiometabolic Health; Council on Epidemiology and Prevention; Council on Clinical Cardiology
Stroke 2014 Aug;45(8):2532-53. Epub 2014 May 20 doi: 10.1161/STR.0000000000000022. PMID: 24846875
González-Gross M, Meléndez A
Nutr Hosp 2013 Sep;28 Suppl 5:89-98. doi: 10.3305/nh.2013.28.sup5.6923. PMID: 24010748
Landry BW, Driscoll SW
PM R 2012 Nov;4(11):826-32. doi: 10.1016/j.pmrj.2012.09.585. PMID: 23174545
Tudor-Locke C, Bassett DR Jr
Sports Med 2004;34(1):1-8. doi: 10.2165/00007256-200434010-00001. PMID: 14715035
Pascual-Leone A, Nguyet D, Cohen LG, Brasil-Neto JP, Cammarota A, Hallett M
J Neurophysiol 1995 Sep;74(3):1037-45. doi: 10.1152/jn.1995.74.3.1037. PMID: 7500130

Diagnosis

Healy S, Nacario A, Braithwaite RE, Hopper C
Autism Res 2018 Jun;11(6):818-833. Epub 2018 Apr 25 doi: 10.1002/aur.1955. PMID: 29693781
Hommel B, Wiers RW
Trends Cogn Sci 2017 Dec;21(12):940-949. doi: 10.1016/j.tics.2017.09.009. PMID: 29150000
Wolpert DM
Cold Spring Harb Symp Quant Biol 2014;79:93-8. Epub 2015 Apr 7 doi: 10.1101/sqb.2014.79.024919. PMID: 25851507Free PMC Article
Kwok CS, Anderson SG, Myint PK, Mamas MA, Loke YK
Int J Cardiol 2014 Dec 15;177(2):467-76. Epub 2014 Sep 28 doi: 10.1016/j.ijcard.2014.09.104. PMID: 25443248
Bennell K, Dobson F, Hinman R
Arthritis Care Res (Hoboken) 2011 Nov;63 Suppl 11:S350-70. doi: 10.1002/acr.20538. PMID: 22588756

Therapy

Mazeas A, Duclos M, Pereira B, Chalabaev A
J Med Internet Res 2022 Jan 4;24(1):e26779. doi: 10.2196/26779. PMID: 34982715Free PMC Article
Poyatos-León R, García-Hermoso A, Sanabria-Martínez G, Álvarez-Bueno C, Cavero-Redondo I, Martínez-Vizcaíno V
Birth 2017 Sep;44(3):200-208. Epub 2017 Jun 6 doi: 10.1111/birt.12294. PMID: 28589648
French B, Thomas LH, Coupe J, McMahon NE, Connell L, Harrison J, Sutton CJ, Tishkovskaya S, Watkins CL
Cochrane Database Syst Rev 2016 Nov 14;11(11):CD006073. doi: 10.1002/14651858.CD006073.pub3. PMID: 27841442Free PMC Article
O'Halloran PD, Blackstock F, Shields N, Holland A, Iles R, Kingsley M, Bernhardt J, Lannin N, Morris ME, Taylor NF
Clin Rehabil 2014 Dec;28(12):1159-71. Epub 2014 Jun 18 doi: 10.1177/0269215514536210. PMID: 24942478
Dobbins M, Husson H, DeCorby K, LaRocca RL
Cochrane Database Syst Rev 2013 Feb 28;2013(2):CD007651. doi: 10.1002/14651858.CD007651.pub2. PMID: 23450577Free PMC Article

Prognosis

Lee DH, Rezende LFM, Joh HK, Keum N, Ferrari G, Rey-Lopez JP, Rimm EB, Tabung FK, Giovannucci EL
Circulation 2022 Aug 16;146(7):523-534. Epub 2022 Jul 25 doi: 10.1161/CIRCULATIONAHA.121.058162. PMID: 35876019Free PMC Article
Chudasama YV, Khunti KK, Zaccardi F, Rowlands AV, Yates T, Gillies CL, Davies MJ, Dhalwani NN
BMC Med 2019 Jun 12;17(1):108. doi: 10.1186/s12916-019-1339-0. PMID: 31186007Free PMC Article
McTiernan A, Friedenreich CM, Katzmarzyk PT, Powell KE, Macko R, Buchner D, Pescatello LS, Bloodgood B, Tennant B, Vaux-Bjerke A, George SM, Troiano RP, Piercy KL; 2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*
Med Sci Sports Exerc 2019 Jun;51(6):1252-1261. doi: 10.1249/MSS.0000000000001937. PMID: 31095082Free PMC Article
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL
Intensive Care Med 2017 Feb;43(2):171-183. Epub 2016 Nov 18 doi: 10.1007/s00134-016-4612-0. PMID: 27864615
Biswas A, Oh PI, Faulkner GE, Bajaj RR, Silver MA, Mitchell MS, Alter DA
Ann Intern Med 2015 Jan 20;162(2):123-32. doi: 10.7326/M14-1651. PMID: 25599350

Clinical prediction guides

Fulk GD, He Y, Boyne P, Dunning K
Stroke 2017 Feb;48(2):406-411. Epub 2017 Jan 5 doi: 10.1161/STROKEAHA.116.015309. PMID: 28057807
Einspieler C, Peharz R, Marschik PB
J Pediatr (Rio J) 2016 May-Jun;92(3 Suppl 1):S64-70. Epub 2016 Mar 17 doi: 10.1016/j.jped.2015.12.003. PMID: 26997356
van Dongen JM, Proper KI, van Wier MF, van der Beek AJ, Bongers PM, van Mechelen W, van Tulder MW
Scand J Work Environ Health 2012 Sep;38(5):393-408. Epub 2012 Jan 24 doi: 10.5271/sjweh.3275. PMID: 22270562
Charansonney OL
Discov Med 2011 Sep;12(64):177-85. PMID: 21955845
Mehrholz J, Wagner K, Rutte K, Meissner D, Pohl M
Arch Phys Med Rehabil 2007 Oct;88(10):1314-9. doi: 10.1016/j.apmr.2007.06.764. PMID: 17908575

Recent systematic reviews

Pojednic R, D'Arpino E, Halliday I, Bantham A
Int J Environ Res Public Health 2022 Apr 20;19(9) doi: 10.3390/ijerph19094981. PMID: 35564376Free PMC Article
Wu PL, Lee M, Huang TT
PLoS One 2017;12(7):e0181515. Epub 2017 Jul 27 doi: 10.1371/journal.pone.0181515. PMID: 28749970Free PMC Article
Aune D, Norat T, Leitzmann M, Tonstad S, Vatten LJ
Eur J Epidemiol 2015 Jul;30(7):529-42. Epub 2015 Jun 20 doi: 10.1007/s10654-015-0056-z. PMID: 26092138
Young MD, Plotnikoff RC, Collins CE, Callister R, Morgan PJ
Obes Rev 2014 Dec;15(12):983-95. Epub 2014 Oct 7 doi: 10.1111/obr.12225. PMID: 25428600
Teixeira PJ, Carraça EV, Markland D, Silva MN, Ryan RM
Int J Behav Nutr Phys Act 2012 Jun 22;9:78. doi: 10.1186/1479-5868-9-78. PMID: 22726453Free PMC Article

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