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Refractory Dedifferentiated Liposarcoma

MedGen UID:
1649152
Concept ID:
C4725859
Neoplastic Process

Definition

Dedifferentiated liposarcoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Dedifferentiated Liposarcoma

Professional guidelines

PubMed

Wagner MJ, Amodu LI, Duh MS, Korves C, Solleza F, Manson SC, Diaz J, Neary MP, Demetri GD
BMC Cancer 2015 Mar 25;15:175. doi: 10.1186/s12885-015-1182-4. PMID: 25885530Free PMC Article

Recent clinical studies

Etiology

Endo M, Kataoka T, Fujiwara T, Tsukushi S, Takahashi M, Kobayashi E, Yamada Y, Tanaka T, Nezu Y, Hiraga H, Wasa J, Nagano A, Nakano K, Nakayama R, Hamada T, Kawano M, Torigoe T, Sakamoto A, Asanuma K, Morii T, Machida R, Sekino Y, Fukuda H, Oda Y, Ozaki T, Tanaka K
BMC Cancer 2023 Mar 8;23(1):219. doi: 10.1186/s12885-023-10693-w. PMID: 36890471Free PMC Article
Schulte B, Mohindra N, Milhem M, Attia S, Robinson S, Monga V, Hirbe AC, Oppelt P, Charlson J, Helenowski I, Abbinanti S, Cehic R, Okuno S, Van Tine BA, Agulnik M
Br J Cancer 2021 Aug;125(4):528-533. Epub 2021 May 28 doi: 10.1038/s41416-021-01448-0. PMID: 34050255Free PMC Article
Mir O, Azaro A, Merchan J, Chugh R, Trent J, Rodon J, Ohnmacht U, Diener JT, Smith C, Yuen E, Oakley GJ 3rd, Le Cesne A, Soria JC, Benhadji KA, Massard C
Eur J Cancer 2018 Nov;103:88-97. Epub 2018 Sep 12 doi: 10.1016/j.ejca.2018.08.012. PMID: 30218977
Reichardt P
Future Oncol 2014 Jun;10(8 Suppl):s19-27. doi: 10.2217/fon.14.116. PMID: 25048045
Mahmood ST, Agresta S, Vigil CE, Zhao X, Han G, D'Amato G, Calitri CE, Dean M, Garrett C, Schell MJ, Antonia S, Chiappori A
Int J Cancer 2011 Oct 15;129(8):1963-9. Epub 2011 Mar 25 doi: 10.1002/ijc.25843. PMID: 21154746Free PMC Article

Diagnosis

Endo M, Kataoka T, Fujiwara T, Tsukushi S, Takahashi M, Kobayashi E, Yamada Y, Tanaka T, Nezu Y, Hiraga H, Wasa J, Nagano A, Nakano K, Nakayama R, Hamada T, Kawano M, Torigoe T, Sakamoto A, Asanuma K, Morii T, Machida R, Sekino Y, Fukuda H, Oda Y, Ozaki T, Tanaka K
BMC Cancer 2023 Mar 8;23(1):219. doi: 10.1186/s12885-023-10693-w. PMID: 36890471Free PMC Article
Noguchi R, Yoshimatsu Y, Ono T, Sei A, Hirabayashi K, Ozawa I, Kikuta K, Kondo T
Hum Cell 2021 May;34(3):990-997. Epub 2021 Feb 8 doi: 10.1007/s13577-021-00497-0. PMID: 33555519
Guadagno E, Peltrini R, Stasio L, Fiorentino F, Bucci L, Terracciano L, Insabato L
Int J Colorectal Dis 2019 Oct;34(10):1809-1814. Epub 2019 Sep 9 doi: 10.1007/s00384-019-03394-z. PMID: 31501928
Reichardt P
Future Oncol 2014 Jun;10(8 Suppl):s19-27. doi: 10.2217/fon.14.116. PMID: 25048045
Hartmann JT, Patel S
Drugs 2005;65(2):167-78. doi: 10.2165/00003495-200565020-00002. PMID: 15631540

Therapy

Endo M, Kataoka T, Fujiwara T, Tsukushi S, Takahashi M, Kobayashi E, Yamada Y, Tanaka T, Nezu Y, Hiraga H, Wasa J, Nagano A, Nakano K, Nakayama R, Hamada T, Kawano M, Torigoe T, Sakamoto A, Asanuma K, Morii T, Machida R, Sekino Y, Fukuda H, Oda Y, Ozaki T, Tanaka K
BMC Cancer 2023 Mar 8;23(1):219. doi: 10.1186/s12885-023-10693-w. PMID: 36890471Free PMC Article
Gounder MM, Razak AA, Somaiah N, Chawla S, Martin-Broto J, Grignani G, Schuetze SM, Vincenzi B, Wagner AJ, Chmielowski B, Jones RL, Riedel RF, Stacchiotti S, Loggers ET, Ganjoo KN, Le Cesne A, Italiano A, Garcia Del Muro X, Burgess M, Piperno-Neumann S, Ryan C, Mulcahy MF, Forscher C, Penel N, Okuno S, Elias A, Hartner L, Philip T, Alcindor T, Kasper B, Reichardt P, Lapeire L, Blay JY, Chevreau C, Valverde Morales CM, Schwartz GK, Chen JL, Deshpande H, Davis EJ, Nicholas G, Gröschel S, Hatcher H, Duffaud F, Herráez AC, Beveridge RD, Badalamenti G, Eriksson M, Meyer C, von Mehren M, Van Tine BA, Götze K, Mazzeo F, Yakobson A, Zick A, Lee A, Gonzalez AE, Napolitano A, Dickson MA, Michel D, Meng C, Li L, Liu J, Ben-Shahar O, Van Domelen DR, Walker CJ, Chang H, Landesman Y, Shah JJ, Shacham S, Kauffman MG, Attia S
J Clin Oncol 2022 Aug 1;40(22):2479-2490. Epub 2022 Apr 8 doi: 10.1200/JCO.21.01829. PMID: 35394800Free PMC Article
Cortes J, Schöffski P, Littlefield BA
Cancer Treat Rev 2018 Nov;70:190-198. Epub 2018 Aug 21 doi: 10.1016/j.ctrv.2018.08.008. PMID: 30243063
Pollack SM
Expert Rev Vaccines 2018 Feb;17(2):107-114. Epub 2017 Dec 27 doi: 10.1080/14760584.2018.1419068. PMID: 29280411Free PMC Article
Hartmann JT, Patel S
Drugs 2005;65(2):167-78. doi: 10.2165/00003495-200565020-00002. PMID: 15631540

Prognosis

Gounder MM, Razak AA, Somaiah N, Chawla S, Martin-Broto J, Grignani G, Schuetze SM, Vincenzi B, Wagner AJ, Chmielowski B, Jones RL, Riedel RF, Stacchiotti S, Loggers ET, Ganjoo KN, Le Cesne A, Italiano A, Garcia Del Muro X, Burgess M, Piperno-Neumann S, Ryan C, Mulcahy MF, Forscher C, Penel N, Okuno S, Elias A, Hartner L, Philip T, Alcindor T, Kasper B, Reichardt P, Lapeire L, Blay JY, Chevreau C, Valverde Morales CM, Schwartz GK, Chen JL, Deshpande H, Davis EJ, Nicholas G, Gröschel S, Hatcher H, Duffaud F, Herráez AC, Beveridge RD, Badalamenti G, Eriksson M, Meyer C, von Mehren M, Van Tine BA, Götze K, Mazzeo F, Yakobson A, Zick A, Lee A, Gonzalez AE, Napolitano A, Dickson MA, Michel D, Meng C, Li L, Liu J, Ben-Shahar O, Van Domelen DR, Walker CJ, Chang H, Landesman Y, Shah JJ, Shacham S, Kauffman MG, Attia S
J Clin Oncol 2022 Aug 1;40(22):2479-2490. Epub 2022 Apr 8 doi: 10.1200/JCO.21.01829. PMID: 35394800Free PMC Article
Tsuchiya R, Yoshimatsu Y, Noguchi R, Ono T, Sei A, Takeshita F, Sugaya J, Fukushima S, Yoshida A, Ohtori S, Kawai A, Kondo T
Hum Cell 2021 May;34(3):1008-1018. Epub 2021 Mar 6 doi: 10.1007/s13577-021-00515-1. PMID: 33677797
Noguchi R, Yoshimatsu Y, Ono T, Sei A, Hirabayashi K, Ozawa I, Kikuta K, Kondo T
Hum Cell 2021 May;34(3):990-997. Epub 2021 Feb 8 doi: 10.1007/s13577-021-00497-0. PMID: 33555519
Tsuchiya R, Yoshimatsu Y, Noguchi R, Sei A, Takeshita F, Sugaya J, Fukushima S, Yoshida A, Ohtori S, Kawai A, Kondo T
Hum Cell 2021 Jan;34(1):260-270. Epub 2020 Sep 19 doi: 10.1007/s13577-020-00436-5. PMID: 32949334
Pollack SM
Expert Rev Vaccines 2018 Feb;17(2):107-114. Epub 2017 Dec 27 doi: 10.1080/14760584.2018.1419068. PMID: 29280411Free PMC Article

Clinical prediction guides

Gounder MM, Razak AA, Somaiah N, Chawla S, Martin-Broto J, Grignani G, Schuetze SM, Vincenzi B, Wagner AJ, Chmielowski B, Jones RL, Riedel RF, Stacchiotti S, Loggers ET, Ganjoo KN, Le Cesne A, Italiano A, Garcia Del Muro X, Burgess M, Piperno-Neumann S, Ryan C, Mulcahy MF, Forscher C, Penel N, Okuno S, Elias A, Hartner L, Philip T, Alcindor T, Kasper B, Reichardt P, Lapeire L, Blay JY, Chevreau C, Valverde Morales CM, Schwartz GK, Chen JL, Deshpande H, Davis EJ, Nicholas G, Gröschel S, Hatcher H, Duffaud F, Herráez AC, Beveridge RD, Badalamenti G, Eriksson M, Meyer C, von Mehren M, Van Tine BA, Götze K, Mazzeo F, Yakobson A, Zick A, Lee A, Gonzalez AE, Napolitano A, Dickson MA, Michel D, Meng C, Li L, Liu J, Ben-Shahar O, Van Domelen DR, Walker CJ, Chang H, Landesman Y, Shah JJ, Shacham S, Kauffman MG, Attia S
J Clin Oncol 2022 Aug 1;40(22):2479-2490. Epub 2022 Apr 8 doi: 10.1200/JCO.21.01829. PMID: 35394800Free PMC Article
Tsuchiya R, Yoshimatsu Y, Noguchi R, Ono T, Sei A, Takeshita F, Sugaya J, Fukushima S, Yoshida A, Ohtori S, Kawai A, Kondo T
Hum Cell 2021 May;34(3):1008-1018. Epub 2021 Mar 6 doi: 10.1007/s13577-021-00515-1. PMID: 33677797
Schmoll HJ, Lindner LH, Reichardt P, Heißner K, Kopp HG, Kessler T, Mayer-Steinacker R, Rüssel J, Egerer G, Crysandt M, Kasper B, Niederwieser D, Kunitz A, Eigendorff E, Petersen I, Steighardt J, Cygon F, Meinert F, Stein A
JAMA Oncol 2021 Feb 1;7(2):255-262. doi: 10.1001/jamaoncol.2020.6564. PMID: 33355646Free PMC Article
Cortes J, Schöffski P, Littlefield BA
Cancer Treat Rev 2018 Nov;70:190-198. Epub 2018 Aug 21 doi: 10.1016/j.ctrv.2018.08.008. PMID: 30243063
Liu C, Cui Q, Guo J, Li D, Zeng Y
Pathol Oncol Res 2014 Apr;20(2):229-34. Epub 2014 Jan 21 doi: 10.1007/s12253-013-9673-6. PMID: 24446082

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