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Secondary syringomyelia

MedGen UID:
1649806
Concept ID:
C4749399
Disease or Syndrome
Synonym: secondary syringomyelia
SNOMED CT: Secondary syringomyelia (770683002)
 
Monarch Initiative: MONDO:0020509
Orphanet: ORPHA99857

Definition

A rare medullar disease defined as a development of a fluid-filled cavity or syrinx within the spinal cord due to blockage of cerebrospinal fluid circulation (for example due to basal arachnoiditis, meningeal carcinomatosis, various mass lesions), spinal cord injury (for example due to trauma, radiation necrosis, spinal abscess), spinal dysraphism or intramedullary neoplasm. It presents with neuropathic pain, numbness, muscular weakness, changes in tone or spasticity or autonomic changes (hyperhidrosis, heart rate or blood pressure instability). Selective loss of pain and temperature with relative preservation of dorsal column function (touch and pressure) are classic findings. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSecondary syringomyelia

Professional guidelines

PubMed

Tator CH, Meguro K, Rowed DW
J Neurosurg 1982 Apr;56(4):517-23. doi: 10.3171/jns.1982.56.4.0517. PMID: 7062122

Recent clinical studies

Etiology

Cerda-Gonzalez S, Olby NJ, Griffith EH
J Vet Intern Med 2016 Jul;30(4):1090-8. Epub 2016 Jun 17 doi: 10.1111/jvim.14362. PMID: 27311874Free PMC Article

Diagnosis

Cerda-Gonzalez S, Olby NJ, Griffith EH
J Vet Intern Med 2016 Jul;30(4):1090-8. Epub 2016 Jun 17 doi: 10.1111/jvim.14362. PMID: 27311874Free PMC Article
Bouras TI, Kouyialis AT, Boviatsis EJ, Sakas DE
Br J Neurosurg 2006 Feb;20(1):48-50. doi: 10.1080/02688690600601077. PMID: 16698611
Nagai M, Sakuma R, Aoki M, Abe K, Itoyama Y
J Neurol Sci 2000 Aug 1;177(1):60-4. doi: 10.1016/s0022-510x(00)00338-5. PMID: 10967183
Keung YK, Cobos E, Whitehead RP, Roberson GH
Am J Clin Oncol 1997 Dec;20(6):577-9. doi: 10.1097/00000421-199712000-00009. PMID: 9391544
Irikura T, Johki T, Tanaka H, Nakajima M, Yasue M, Sakai H, Nakamura N
Neurol Med Chir (Tokyo) 1990 Nov;30(12):966-71. doi: 10.2176/nmc.30.966. PMID: 1710327

Therapy

Ben Nsir A, Boubaker A, Jemel H
Childs Nerv Syst 2016 Apr;32(4):727-31. Epub 2015 Aug 16 doi: 10.1007/s00381-015-2875-3. PMID: 26277360

Prognosis

Cerda-Gonzalez S, Olby NJ, Griffith EH
J Vet Intern Med 2016 Jul;30(4):1090-8. Epub 2016 Jun 17 doi: 10.1111/jvim.14362. PMID: 27311874Free PMC Article
Ben Nsir A, Boubaker A, Jemel H
Childs Nerv Syst 2016 Apr;32(4):727-31. Epub 2015 Aug 16 doi: 10.1007/s00381-015-2875-3. PMID: 26277360
Jarupant W, Sithinamsuwan P, Udommongkol C, Reuarrom K, Nidhinandana S, Suwantamee J
J Med Assoc Thai 2004 Oct;87(10):1244-9. PMID: 15560705

Clinical prediction guides

Cerda-Gonzalez S, Olby NJ, Griffith EH
J Vet Intern Med 2016 Jul;30(4):1090-8. Epub 2016 Jun 17 doi: 10.1111/jvim.14362. PMID: 27311874Free PMC Article

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