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Refractory Indolent Adult Non-Hodgkin Lymphoma

MedGen UID:
1658705
Concept ID:
C4724875
Neoplastic Process

Definition

Indolent adult non-Hodgkin lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Indolent Adult Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Silkenstedt E, Dreyling M
Hematol Oncol 2023 Jun;41 Suppl 1:36-42. doi: 10.1002/hon.3149. PMID: 37294961
Silkenstedt E, Linton K, Dreyling M
Br J Haematol 2021 Oct;195(2):162-173. Epub 2021 Mar 30 doi: 10.1111/bjh.17419. PMID: 33783838
Smolewski P, Rydygier D, Robak T
Expert Opin Pharmacother 2019 Oct;20(15):1893-1905. Epub 2019 Aug 2 doi: 10.1080/14656566.2019.1642871. PMID: 31373238

Recent clinical studies

Etiology

Denlinger N, Bond D, Jaglowski S
Curr Probl Cancer 2022 Feb;46(1):100826. Epub 2021 Dec 25 doi: 10.1016/j.currproblcancer.2021.100826. PMID: 35012754Free PMC Article
Jacobson CA, Chavez JC, Sehgal AR, William BM, Munoz J, Salles G, Munshi PN, Casulo C, Maloney DG, de Vos S, Reshef R, Leslie LA, Yakoub-Agha I, Oluwole OO, Fung HCH, Rosenblatt J, Rossi JM, Goyal L, Plaks V, Yang Y, Vezan R, Avanzi MP, Neelapu SS
Lancet Oncol 2022 Jan;23(1):91-103. Epub 2021 Dec 8 doi: 10.1016/S1470-2045(21)00591-X. PMID: 34895487
Abramson JS, Palomba ML, Gordon LI, Lunning MA, Wang M, Arnason J, Mehta A, Purev E, Maloney DG, Andreadis C, Sehgal A, Solomon SR, Ghosh N, Albertson TM, Garcia J, Kostic A, Mallaney M, Ogasawara K, Newhall K, Kim Y, Li D, Siddiqi T
Lancet 2020 Sep 19;396(10254):839-852. Epub 2020 Sep 1 doi: 10.1016/S0140-6736(20)31366-0. PMID: 32888407
Leonard JP, Trneny M, Izutsu K, Fowler NH, Hong X, Zhu J, Zhang H, Offner F, Scheliga A, Nowakowski GS, Pinto A, Re F, Fogliatto LM, Scheinberg P, Flinn IW, Moreira C, Cabeçadas J, Liu D, Kalambakas S, Fustier P, Wu C, Gribben JG; AUGMENT Trial Investigators
J Clin Oncol 2019 May 10;37(14):1188-1199. Epub 2019 Mar 21 doi: 10.1200/JCO.19.00010. PMID: 30897038Free PMC Article
Rummel MJ, Niederle N, Maschmeyer G, Banat GA, von Grünhagen U, Losem C, Kofahl-Krause D, Heil G, Welslau M, Balser C, Kaiser U, Weidmann E, Dürk H, Ballo H, Stauch M, Roller F, Barth J, Hoelzer D, Hinke A, Brugger W; Study group indolent Lymphomas (StiL)
Lancet 2013 Apr 6;381(9873):1203-10. Epub 2013 Feb 20 doi: 10.1016/S0140-6736(12)61763-2. PMID: 23433739

Diagnosis

Silkenstedt E, Dreyling M
Hematol Oncol 2023 Jun;41 Suppl 1:36-42. doi: 10.1002/hon.3149. PMID: 37294961
Daniel A, Ghez D, Ravaiau C, Cavalieri D, Tournilhac O, Herbaux C, Roriz M, Wemeau M, Guillet S, Bossard JB, Hélène D, Kaphan E, Caroline R, Florence L, Pierache A, Michel M, Godeau B, Terriou L
Eur J Haematol 2022 Dec;109(6):719-727. Epub 2022 Sep 20 doi: 10.1111/ejh.13858. PMID: 36048142Free PMC Article
Maheswari SU, Sampath V, Ramesh A
Indian J Dermatol Venereol Leprol 2018;84(2):169-173. doi: 10.4103/ijdvl.IJDVL_727_16. PMID: 29067930
Sears NC, Singh A, Singh AD
J Glaucoma 2016 Aug;25(8):e741-4. doi: 10.1097/IJG.0000000000000459. PMID: 27300646
Rummel MJ, Niederle N, Maschmeyer G, Banat GA, von Grünhagen U, Losem C, Kofahl-Krause D, Heil G, Welslau M, Balser C, Kaiser U, Weidmann E, Dürk H, Ballo H, Stauch M, Roller F, Barth J, Hoelzer D, Hinke A, Brugger W; Study group indolent Lymphomas (StiL)
Lancet 2013 Apr 6;381(9873):1203-10. Epub 2013 Feb 20 doi: 10.1016/S0140-6736(12)61763-2. PMID: 23433739

Therapy

Frampton JE
Drugs 2023 Sep;83(14):1331-1340. doi: 10.1007/s40265-023-01930-4. PMID: 37597091
Denlinger N, Bond D, Jaglowski S
Curr Probl Cancer 2022 Feb;46(1):100826. Epub 2021 Dec 25 doi: 10.1016/j.currproblcancer.2021.100826. PMID: 35012754Free PMC Article
Jacobson CA, Chavez JC, Sehgal AR, William BM, Munoz J, Salles G, Munshi PN, Casulo C, Maloney DG, de Vos S, Reshef R, Leslie LA, Yakoub-Agha I, Oluwole OO, Fung HCH, Rosenblatt J, Rossi JM, Goyal L, Plaks V, Yang Y, Vezan R, Avanzi MP, Neelapu SS
Lancet Oncol 2022 Jan;23(1):91-103. Epub 2021 Dec 8 doi: 10.1016/S1470-2045(21)00591-X. PMID: 34895487
Leonard JP, Trneny M, Izutsu K, Fowler NH, Hong X, Zhu J, Zhang H, Offner F, Scheliga A, Nowakowski GS, Pinto A, Re F, Fogliatto LM, Scheinberg P, Flinn IW, Moreira C, Cabeçadas J, Liu D, Kalambakas S, Fustier P, Wu C, Gribben JG; AUGMENT Trial Investigators
J Clin Oncol 2019 May 10;37(14):1188-1199. Epub 2019 Mar 21 doi: 10.1200/JCO.19.00010. PMID: 30897038Free PMC Article
Rummel MJ, Niederle N, Maschmeyer G, Banat GA, von Grünhagen U, Losem C, Kofahl-Krause D, Heil G, Welslau M, Balser C, Kaiser U, Weidmann E, Dürk H, Ballo H, Stauch M, Roller F, Barth J, Hoelzer D, Hinke A, Brugger W; Study group indolent Lymphomas (StiL)
Lancet 2013 Apr 6;381(9873):1203-10. Epub 2013 Feb 20 doi: 10.1016/S0140-6736(12)61763-2. PMID: 23433739

Prognosis

Lu T, Zhang J, McCracken JM, Young KH
Cancer Treat Rev 2024 Jan;122:102651. Epub 2023 Nov 4 doi: 10.1016/j.ctrv.2023.102651. PMID: 37976759
Silkenstedt E, Dreyling M
Hematol Oncol 2023 Jun;41 Suppl 1:36-42. doi: 10.1002/hon.3149. PMID: 37294961
Hutchings M, Morschhauser F, Iacoboni G, Carlo-Stella C, Offner FC, Sureda A, Salles G, Martínez-Lopez J, Crump M, Thomas DN, Morcos PN, Ferlini C, Bröske AE, Belousov A, Bacac M, Dimier N, Carlile DJ, Lundberg L, Perez-Callejo D, Umaña P, Moore T, Weisser M, Dickinson MJ
J Clin Oncol 2021 Jun 20;39(18):1959-1970. Epub 2021 Mar 19 doi: 10.1200/JCO.20.03175. PMID: 33739857Free PMC Article
Advani R, Flinn I, Popplewell L, Forero A, Bartlett NL, Ghosh N, Kline J, Roschewski M, LaCasce A, Collins GP, Tran T, Lynn J, Chen JY, Volkmer JP, Agoram B, Huang J, Majeti R, Weissman IL, Takimoto CH, Chao MP, Smith SM
N Engl J Med 2018 Nov 1;379(18):1711-1721. doi: 10.1056/NEJMoa1807315. PMID: 30380386Free PMC Article
Sehn LH, Chua N, Mayer J, Dueck G, Trněný M, Bouabdallah K, Fowler N, Delwail V, Press O, Salles G, Gribben J, Lennard A, Lugtenburg PJ, Dimier N, Wassner-Fritsch E, Fingerle-Rowson G, Cheson BD
Lancet Oncol 2016 Aug;17(8):1081-1093. Epub 2016 Jun 23 doi: 10.1016/S1470-2045(16)30097-3. PMID: 27345636

Clinical prediction guides

Melani C, Lakhotia R, Pittaluga S, Phelan JD, Huang DW, Wright G, Simard J, Muppidi J, Thomas CJ, Ceribelli M, Tosto FA, Yang Y, Xu W, Davies-Hill T, Pack SD, Peer CJ, Arisa O, Mena E, Lindenberg L, Bergvall E, Portell CA, Farah RJ, Lee ST, Pradhan A, Morrison C, Tadese A, Juanitez AM, Lu C, Jacob A, Simmons H, Figg WD, Steinberg SM, Jaffe ES, Roschewski M, Staudt LM, Wilson WH
N Engl J Med 2024 Jun 20;390(23):2143-2155. doi: 10.1056/NEJMoa2401532. PMID: 38899693Free PMC Article
Daniel A, Ghez D, Ravaiau C, Cavalieri D, Tournilhac O, Herbaux C, Roriz M, Wemeau M, Guillet S, Bossard JB, Hélène D, Kaphan E, Caroline R, Florence L, Pierache A, Michel M, Godeau B, Terriou L
Eur J Haematol 2022 Dec;109(6):719-727. Epub 2022 Sep 20 doi: 10.1111/ejh.13858. PMID: 36048142Free PMC Article
Jacobson CA, Chavez JC, Sehgal AR, William BM, Munoz J, Salles G, Munshi PN, Casulo C, Maloney DG, de Vos S, Reshef R, Leslie LA, Yakoub-Agha I, Oluwole OO, Fung HCH, Rosenblatt J, Rossi JM, Goyal L, Plaks V, Yang Y, Vezan R, Avanzi MP, Neelapu SS
Lancet Oncol 2022 Jan;23(1):91-103. Epub 2021 Dec 8 doi: 10.1016/S1470-2045(21)00591-X. PMID: 34895487
Hutchings M, Morschhauser F, Iacoboni G, Carlo-Stella C, Offner FC, Sureda A, Salles G, Martínez-Lopez J, Crump M, Thomas DN, Morcos PN, Ferlini C, Bröske AE, Belousov A, Bacac M, Dimier N, Carlile DJ, Lundberg L, Perez-Callejo D, Umaña P, Moore T, Weisser M, Dickinson MJ
J Clin Oncol 2021 Jun 20;39(18):1959-1970. Epub 2021 Mar 19 doi: 10.1200/JCO.20.03175. PMID: 33739857Free PMC Article
Advani R, Flinn I, Popplewell L, Forero A, Bartlett NL, Ghosh N, Kline J, Roschewski M, LaCasce A, Collins GP, Tran T, Lynn J, Chen JY, Volkmer JP, Agoram B, Huang J, Majeti R, Weissman IL, Takimoto CH, Chao MP, Smith SM
N Engl J Med 2018 Nov 1;379(18):1711-1721. doi: 10.1056/NEJMoa1807315. PMID: 30380386Free PMC Article

Recent systematic reviews

Wang Z, Zhou H, Xu J, Wang J, Niu T
Front Immunol 2022;13:1070660. Epub 2023 Jan 4 doi: 10.3389/fimmu.2022.1070660. PMID: 36685572Free PMC Article
Vidal L, Gafter-Gvili A, Leibovici L, Shpilberg O
Cochrane Database Syst Rev 2009 Apr 15;(2):CD006552. doi: 10.1002/14651858.CD006552.pub2. PMID: 19370640
Cheung MC, Haynes AE, Stevens A, Meyer RM, Imrie K; Members of the Hematology Disease Site Group of the Cancer Care Ontario Program in Evidence-Based Care
Leuk Lymphoma 2006 Jun;47(6):967-77. doi: 10.1080/10428190600572582. PMID: 16840185
Gustavsson A, Osterman B, Cavallin-Ståhl E
Acta Oncol 2003;42(5-6):605-19. doi: 10.1080/02841860310014435. PMID: 14596518

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