U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent bacterial upper respiratory tract infections

MedGen UID:
1670943
•Concept ID:
C4732772
•
Disease or Syndrome
Synonym: Recurrent bacterial URI
 
HPO: HP:0031949

Definition

An increased susceptibility to bacterial upper respiratory tract infections as manifested by a history of recurrent bacterial upper respiratory tract infections (running ears - otitis, sinusitis, pharyngitis, tonsillitis). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent bacterial upper respiratory tract infections

Professional guidelines

PubMed

Tonsillitis and Tonsilloliths: Diagnosis and Management.
Smith KL, Hughes R, Myrex P
Am Fam Physician 2023 Jan;107(1):35-41. PMID: 36689967
Management of bronchiectasis in adults.
Visser SK, Bye P, Morgan L
Med J Aust 2018 Aug 20;209(4):177-183. doi: 10.5694/mja17.01195. PMID: 30107772
Clinical practice guideline (update): adult sinusitis.
Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Ashok Kumar K, Kramper M, Orlandi RR, Palmer JN, Patel ZM, Peters A, Walsh SA, Corrigan MD
Otolaryngol Head Neck Surg 2015 Apr;152(2 Suppl):S1-S39. doi: 10.1177/0194599815572097. PMID: 25832968

Recent clinical studies

Etiology

Alterations of intestinal flora and the effects of probiotics in children with recurrent respiratory tract infection.
Li KL, Wang BZ, Li ZP, Li YL, Liang JJ
World J Pediatr 2019 Jun;15(3):255-261. Epub 2019 Apr 24 doi: 10.1007/s12519-019-00248-0. PMID: 31020541Free PMC Article
Bacterial lysates in the prevention of respiratory tract infections.
Jurkiewicz D, Zielnik-Jurkiewicz B
Otolaryngol Pol 2018 Oct 31;72(5):1-8. doi: 10.5604/01.3001.0012.7216. PMID: 30460909
Infection-related asthma.
Darveaux JI, Lemanske RF Jr
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):658-63. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.011. PMID: 25439354Free PMC Article
Pediatric asthma phenotypes.
Cowan K, Guilbert TW
Curr Opin Pediatr 2012 Jun;24(3):344-51. doi: 10.1097/MOP.0b013e32835357ab. PMID: 22572759
Upper respiratory tract infections.
Jain N, Lodha R, Kabra SK
Indian J Pediatr 2001 Dec;68(12):1135-8. doi: 10.1007/BF02722930. PMID: 11838568Free PMC Article

Diagnosis

Hyper IgE Syndromes.
Gracci S, Novelli T, D'Elios S, Bernardini R, Peroni D
Curr Pediatr Rev 2024;20(3):253-264. doi: 10.2174/1573396320666230912103124. PMID: 37702167
Tonsillitis and Tonsilloliths: Diagnosis and Management.
Smith KL, Hughes R, Myrex P
Am Fam Physician 2023 Jan;107(1):35-41. PMID: 36689967
Microbiology of Cystic Fibrosis Airway Disease.
Blanchard AC, Waters VJ
Semin Respir Crit Care Med 2019 Dec;40(6):727-736. Epub 2019 Dec 30 doi: 10.1055/s-0039-1698464. PMID: 31887768Free PMC Article
Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults.
Pugh R, Grant C, Cooke RP, Dempsey G
Cochrane Database Syst Rev 2015 Aug 24;2015(8):CD007577. doi: 10.1002/14651858.CD007577.pub3. PMID: 26301604Free PMC Article
Upper respiratory tract infections.
Jain N, Lodha R, Kabra SK
Indian J Pediatr 2001 Dec;68(12):1135-8. doi: 10.1007/BF02722930. PMID: 11838568Free PMC Article

Therapy

Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections.
Brandi P, Conejero L, Cueto FJ, Martínez-Cano S, Dunphy G, Gómez MJ, Relaño C, Saz-Leal P, Enamorado M, Quintas A, Dopazo A, Amores-Iniesta J, Del Fresno C, Nistal-Villán E, Ardavín C, Nieto A, Casanovas M, Subiza JL, Sancho D
Cell Rep 2022 Jan 4;38(1):110184. doi: 10.1016/j.celrep.2021.110184. PMID: 34986349Free PMC Article
Current and Future Treatments in Primary Ciliary Dyskinesia.
Paff T, Omran H, Nielsen KG, Haarman EG
Int J Mol Sci 2021 Sep 11;22(18) doi: 10.3390/ijms22189834. PMID: 34575997Free PMC Article
Alterations of intestinal flora and the effects of probiotics in children with recurrent respiratory tract infection.
Li KL, Wang BZ, Li ZP, Li YL, Liang JJ
World J Pediatr 2019 Jun;15(3):255-261. Epub 2019 Apr 24 doi: 10.1007/s12519-019-00248-0. PMID: 31020541Free PMC Article
Rhinoscleroma.
Umphress B, Raparia K
Arch Pathol Lab Med 2018 Dec;142(12):1533-1536. Epub 2018 Aug 31 doi: 10.5858/arpa.2018-0073-RA. PMID: 30168726
Upper respiratory tract infections.
Jain N, Lodha R, Kabra SK
Indian J Pediatr 2001 Dec;68(12):1135-8. doi: 10.1007/BF02722930. PMID: 11838568Free PMC Article

Prognosis

Hyper IgE Syndromes.
Gracci S, Novelli T, D'Elios S, Bernardini R, Peroni D
Curr Pediatr Rev 2024;20(3):253-264. doi: 10.2174/1573396320666230912103124. PMID: 37702167
Acute sinusitis in daily clinical practice.
Arcimowicz M
Otolaryngol Pol 2021 Aug 31;75(4):40-50. doi: 10.5604/01.3001.0015.2378. PMID: 34552023
Microbiology of Cystic Fibrosis Airway Disease.
Blanchard AC, Waters VJ
Semin Respir Crit Care Med 2019 Dec;40(6):727-736. Epub 2019 Dec 30 doi: 10.1055/s-0039-1698464. PMID: 31887768Free PMC Article
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):380-384. doi: 10.2500/aap.2019.40.4252. PMID: 31690375
Legionnaires' disease.
Cunha BA, Burillo A, Bouza E
Lancet 2016 Jan 23;387(10016):376-385. Epub 2015 Jul 28 doi: 10.1016/S0140-6736(15)60078-2. PMID: 26231463

Clinical prediction guides

Hyper IgE Syndromes.
Gracci S, Novelli T, D'Elios S, Bernardini R, Peroni D
Curr Pediatr Rev 2024;20(3):253-264. doi: 10.2174/1573396320666230912103124. PMID: 37702167
Tonsillitis and Tonsilloliths: Diagnosis and Management.
Smith KL, Hughes R, Myrex P
Am Fam Physician 2023 Jan;107(1):35-41. PMID: 36689967
Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.
Windfuhr JP, Toepfner N, Steffen G, Waldfahrer F, Berner R
Eur Arch Otorhinolaryngol 2016 Apr;273(4):973-87. Epub 2016 Jan 11 doi: 10.1007/s00405-015-3872-6. PMID: 26755048Free PMC Article
Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults.
Pugh R, Grant C, Cooke RP, Dempsey G
Cochrane Database Syst Rev 2015 Aug 24;2015(8):CD007577. doi: 10.1002/14651858.CD007577.pub3. PMID: 26301604Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula A
BMJ Clin Evid 2009 Oct 26;2009 PMID: 21718574Free PMC Article

Recent systematic reviews

Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T
Cochrane Database Syst Rev 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. PMID: 33728634Free PMC Article
Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults.
Pugh R, Grant C, Cooke RP, Dempsey G
Cochrane Database Syst Rev 2015 Aug 24;2015(8):CD007577. doi: 10.1002/14651858.CD007577.pub3. PMID: 26301604Free PMC Article
Bronchitis (acute).
Wark P
BMJ Clin Evid 2015 Jul 17;2015 PMID: 26186368Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula PA
BMJ Clin Evid 2014 Jul 22;2014 PMID: 25051184Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula A
BMJ Clin Evid 2009 Oct 26;2009 PMID: 21718574Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...