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Horizontal eyelid laxity

MedGen UID:
1671073
Concept ID:
C4732814
Finding
HPO: HP:0032032

Definition

Abnormally lax eyelid associated with tissue relaxation, predominantly in the horizontal plane. It can be demonstrated by the horizontal eyelid distraction test (e.g. by pulling the eyelid medially and laterally). Medial and/or lateral canthal tendon laxity are often present. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHorizontal eyelid laxity

Professional guidelines

PubMed

AlHarthi AS
Int Ophthalmol 2023 Mar;43(3):1013-1026. Epub 2022 Sep 2 doi: 10.1007/s10792-022-02475-3. PMID: 36053479
Lin P, Kitaguchi Y, Mupas-Uy J, Sabundayo MS, Takahashi Y, Kakizaki H
Int Ophthalmol 2019 Aug;39(8):1895-1907. Epub 2018 Oct 12 doi: 10.1007/s10792-018-1004-1. PMID: 30315389
Miller GR, Tenzel RR, Buffam FV
Arch Ophthalmol 1976 Aug;94(8):1289-90. doi: 10.1001/archopht.1976.03910040161007. PMID: 949270

Recent clinical studies

Etiology

Choi YM, Kim N
Eur J Ophthalmol 2022 Jul;32(4):2078-2084. Epub 2021 Oct 9 doi: 10.1177/11206721211050038. PMID: 34632826
Serbest Ceylanoglu K, Malkoc Sen E, Corak Eroglu F, Yenigun S
J Craniomaxillofac Surg 2021 Nov;49(11):1005-1009. Epub 2021 Jun 19 doi: 10.1016/j.jcms.2021.06.010. PMID: 34176714
Van Slyke AC, Carr LA, Carr NJ
Plast Reconstr Surg 2020 Feb;145(2):306e-315e. doi: 10.1097/PRS.0000000000006484. PMID: 31985625
López-García JS, García-Lozano I, Giménez-Vallejo C, Jiménez B, Sánchez Á, de Juan IE
Graefes Arch Clin Exp Ophthalmol 2017 Mar;255(3):619-625. Epub 2016 Nov 5 doi: 10.1007/s00417-016-3536-2. PMID: 27817116
Damasceno RW, Osaki MH, Dantas PE, Belfort R Jr
Ophthalmic Plast Reconstr Surg 2011 Sep-Oct;27(5):321-6. doi: 10.1097/IOP.0b013e31821637e4. PMID: 21490515

Diagnosis

Hu J, Li Y, Li Q, Wang L, Huang Y
Eur J Ophthalmol 2021 Nov;31(6):3418-3424. Epub 2020 Dec 24 doi: 10.1177/1120672120984398. PMID: 33356531
Van Slyke AC, Carr LA, Carr NJ
Plast Reconstr Surg 2020 Feb;145(2):306e-315e. doi: 10.1097/PRS.0000000000006484. PMID: 31985625
Choung H, Reshef ER, Tanking T, Freitag SK
Orbit 2020 Feb;39(1):23-30. Epub 2019 Feb 7 doi: 10.1080/01676830.2019.1573434. PMID: 30732510
Jones ST, Aakalu VK, Lin AY, Perez C, Epstein G, Putterman AM, Setabutr P
Ophthalmic Plast Reconstr Surg 2017 Jul/Aug;33(4):261-263. doi: 10.1097/IOP.0000000000000737. PMID: 27429229
Cartmill BT, Parham DM, Strike PW, Griffiths L, Parkin B
Orbit 2014 Dec;33(6):437-43. Epub 2014 Sep 22 doi: 10.3109/01676830.2014.950285. PMID: 25244631

Therapy

López-García JS, García-Lozano I, Giménez-Vallejo C, Jiménez B, Sánchez Á, de Juan IE
Graefes Arch Clin Exp Ophthalmol 2017 Mar;255(3):619-625. Epub 2016 Nov 5 doi: 10.1007/s00417-016-3536-2. PMID: 27817116
Cartmill BT, Parham DM, Strike PW, Griffiths L, Parkin B
Orbit 2014 Dec;33(6):437-43. Epub 2014 Sep 22 doi: 10.3109/01676830.2014.950285. PMID: 25244631
Luu ST, Cannon PS, Selva D
Ophthalmic Plast Reconstr Surg 2010 Sep-Oct;26(5):344-7. doi: 10.1097/IOP.0b013e3181c9bb3b. PMID: 20592635

Prognosis

Choi YM, Kim N
Eur J Ophthalmol 2022 Jul;32(4):2078-2084. Epub 2021 Oct 9 doi: 10.1177/11206721211050038. PMID: 34632826
Serbest Ceylanoglu K, Malkoc Sen E, Corak Eroglu F, Yenigun S
J Craniomaxillofac Surg 2021 Nov;49(11):1005-1009. Epub 2021 Jun 19 doi: 10.1016/j.jcms.2021.06.010. PMID: 34176714
Van Slyke AC, Carr LA, Carr NJ
Plast Reconstr Surg 2020 Feb;145(2):306e-315e. doi: 10.1097/PRS.0000000000006484. PMID: 31985625
Choung H, Reshef ER, Tanking T, Freitag SK
Orbit 2020 Feb;39(1):23-30. Epub 2019 Feb 7 doi: 10.1080/01676830.2019.1573434. PMID: 30732510
López-García JS, García-Lozano I, Giménez-Vallejo C, Jiménez B, Sánchez Á, de Juan IE
Graefes Arch Clin Exp Ophthalmol 2017 Mar;255(3):619-625. Epub 2016 Nov 5 doi: 10.1007/s00417-016-3536-2. PMID: 27817116

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