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Refractory Subcutaneous Panniculitis-Like T-Cell Lymphoma

MedGen UID:
1680704
•Concept ID:
C4763800
•
Neoplastic Process

Definition

Subcutaneous panniculitis-like T-cell lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Subcutaneous Panniculitis-Like T-Cell Lymphoma

Recent clinical studies

Etiology

Subcutaneous panniculitis-like T-cell lymphoma associated with hemophagocytic lymphohistiocytosis: a systematic review of 63 patients reported in the literature.
Ou W, Zhao Y, Wei A, Ma H, Zhang L, Lian H, Zhang Q, Wang D, Li Z, Wang T, Zhang R
Clin Exp Med 2023 Dec;23(8):4575-4583. Epub 2023 Oct 16 doi: 10.1007/s10238-023-01210-1. PMID: 37840116
Ruxolitinib bridging therapy to allogeneic SCT for high-risk refractory subcutaneous panniculitis-like T-cell lymphoma.
Watson LR, Lew TE, Fox LC, Khot A, van der Weyden C
Leuk Lymphoma 2022 Dec;63(13):3217-3221. Epub 2022 Sep 7 doi: 10.1080/10428194.2022.2118537. PMID: 36070587
Facial swelling: an atypical presentation of cutaneous lymphoma.
Lee WJ, Moon IJ, Won CH, Chang SE, Choi JH, Moon KC, Lee MW
Int J Dermatol 2016 Aug;55(8):e440-6. Epub 2016 Mar 5 doi: 10.1111/ijd.13260. PMID: 26945567
Hematopoietic stem cell transplantation for primary cutaneous γδ T-cell lymphoma and refractory subcutaneous panniculitis-like T-cell lymphoma.
Gibson JF, Alpdogan O, Subtil A, Girardi M, Wilson LD, Roberts K, Foss F
J Am Acad Dermatol 2015 Jun;72(6):1010-5.e5. doi: 10.1016/j.jaad.2015.01.003. PMID: 25981001
Efficacy of denileukin diftitox in subcutaneous panniculitis-like T-cell lymphoma.
Hathaway T, Subtil A, Kuo P, Foss F
Clin Lymphoma Myeloma 2007 Sep;7(8):541-5. doi: 10.3816/clm.2007.n.040. PMID: 18021473

Diagnosis

Subcutaneous panniculitis-like T-cell lymphoma associated with hemophagocytic lymphohistiocytosis: a systematic review of 63 patients reported in the literature.
Ou W, Zhao Y, Wei A, Ma H, Zhang L, Lian H, Zhang Q, Wang D, Li Z, Wang T, Zhang R
Clin Exp Med 2023 Dec;23(8):4575-4583. Epub 2023 Oct 16 doi: 10.1007/s10238-023-01210-1. PMID: 37840116
Subcutaneous Panniculitis-like T-cell Lymphoma Lacking Subcutaneous Tumor Mimicking Adult-onset Still's Disease.
Tada M, Kachi S, Onozawa M, Fujieda Y, Yoshida S, Oki Y, Kamada K, Nagai J, Okada S, Kikuchi R, Hisada R, Hasegawa Y, Ohigashi H, Goto H, Hashimoto D, Nakazato S, Matsuno Y, Teshima T, Atsumi T
Intern Med 2023 Nov 1;62(21):3231-3235. Epub 2023 Mar 15 doi: 10.2169/internalmedicine.1419-22. PMID: 36927968Free PMC Article
The pathophysiology and current treatments for the subcutaneous panniculitis-like T cell lymphoma: An updated review.
Lin EC, Liao JB, Fang YH, Hong CH
Asia Pac J Clin Oncol 2023 Feb;19(1):27-34. Epub 2022 May 4 doi: 10.1111/ajco.13787. PMID: 35509196
Cyclosporin in subcutaneous panniculitis-like T-cell lymphoma.
Rojnuckarin P, Nakorn TN, Assanasen T, Wannakrairot P, Intragumtornchai T
Leuk Lymphoma 2007 Mar;48(3):560-3. doi: 10.1080/10428190601078456. PMID: 17454599
Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature.
Go RS, Wester SM
Cancer 2004 Sep 15;101(6):1404-13. doi: 10.1002/cncr.20502. PMID: 15368328

Therapy

Pediatric Subcutaneous Panniculitis-like T-Cell Lymphoma With Hemophagocytosis Showing Complete Resolution With the BFM90 Protocol: Case Report and Review of Literature.
Singh S, Philip CC, John MJ
J Pediatr Hematol Oncol 2019 Aug;41(6):478-481. doi: 10.1097/MPH.0000000000001434. PMID: 30730380
A Case of Refractory Subcutaneous Panniculitis-like T-cell Lymphoma with Bone Marrow and Lung Involvement Treated Successfully with Oral Etoposide.
Saito A, Okiyama N, Tanaka R, Maruyama H, Fujimoto M
Acta Derm Venereol 2018 Jun 8;98(6):610-611. doi: 10.2340/00015555-2932. PMID: 29881869
Facial swelling: an atypical presentation of cutaneous lymphoma.
Lee WJ, Moon IJ, Won CH, Chang SE, Choi JH, Moon KC, Lee MW
Int J Dermatol 2016 Aug;55(8):e440-6. Epub 2016 Mar 5 doi: 10.1111/ijd.13260. PMID: 26945567
Hematopoietic stem cell transplantation for primary cutaneous γδ T-cell lymphoma and refractory subcutaneous panniculitis-like T-cell lymphoma.
Gibson JF, Alpdogan O, Subtil A, Girardi M, Wilson LD, Roberts K, Foss F
J Am Acad Dermatol 2015 Jun;72(6):1010-5.e5. doi: 10.1016/j.jaad.2015.01.003. PMID: 25981001
Cyclosporin in subcutaneous panniculitis-like T-cell lymphoma.
Rojnuckarin P, Nakorn TN, Assanasen T, Wannakrairot P, Intragumtornchai T
Leuk Lymphoma 2007 Mar;48(3):560-3. doi: 10.1080/10428190601078456. PMID: 17454599

Prognosis

Subcutaneous panniculitis-like T-cell lymphoma associated with hemophagocytic lymphohistiocytosis: a systematic review of 63 patients reported in the literature.
Ou W, Zhao Y, Wei A, Ma H, Zhang L, Lian H, Zhang Q, Wang D, Li Z, Wang T, Zhang R
Clin Exp Med 2023 Dec;23(8):4575-4583. Epub 2023 Oct 16 doi: 10.1007/s10238-023-01210-1. PMID: 37840116
Local radiation for cutaneous T-cell lymphoma other than mycosis fungoides and Sézary syndrome.
Shikama N
Chin Clin Oncol 2019 Feb;8(1):8. Epub 2018 Jul 19 doi: 10.21037/cco.2018.07.01. PMID: 30180750
Hematopoietic stem cell transplantation for primary cutaneous γδ T-cell lymphoma and refractory subcutaneous panniculitis-like T-cell lymphoma.
Gibson JF, Alpdogan O, Subtil A, Girardi M, Wilson LD, Roberts K, Foss F
J Am Acad Dermatol 2015 Jun;72(6):1010-5.e5. doi: 10.1016/j.jaad.2015.01.003. PMID: 25981001
Cyclosporin in subcutaneous panniculitis-like T-cell lymphoma.
Rojnuckarin P, Nakorn TN, Assanasen T, Wannakrairot P, Intragumtornchai T
Leuk Lymphoma 2007 Mar;48(3):560-3. doi: 10.1080/10428190601078456. PMID: 17454599
Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature.
Go RS, Wester SM
Cancer 2004 Sep 15;101(6):1404-13. doi: 10.1002/cncr.20502. PMID: 15368328

Clinical prediction guides

Case report: Successful treatment of Chidamide in a refractory/recurrent SPTCL with ARID1A mutation on the basis of CHOP plus auto-HSCT.
Zhang N, Zhang S, Ma L, Qiu L, Meng QL, Cai J, Xu Z, Yao H, Fan FY
Medicine (Baltimore) 2023 Oct 6;102(40):e35413. doi: 10.1097/MD.0000000000035413. PMID: 37800816Free PMC Article
Durable remission in a patient with refractory subcutaneous panniculitis-like T-cell lymphoma relapse after allogeneic hematopoietic stem cell transplantation through withdrawal of cyclosporine.
Yuan L, Sun L, Bo J, Zhou Y, Li HH, Yu L, Gao CJ
Ann Transplant 2011 Jul-Sep;16(3):135-8. doi: 10.12659/aot.882007. PMID: 21959522
Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature.
Go RS, Wester SM
Cancer 2004 Sep 15;101(6):1404-13. doi: 10.1002/cncr.20502. PMID: 15368328

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