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Abnormal circulating polysaccharide concentration

MedGen UID:
1684710
•Concept ID:
C5139057
•
Finding
Synonym: Abnormality of polysaccharide metabolism
 
HPO: HP:0011012

Definition

A deviation from the normal concentration of a polysaccharide in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating polysaccharide concentration

Conditions with this feature

Polysaccharide, storage of unusual
MedGen UID:
376645
•Concept ID:
C1849721
•
Pathologic Function
See: Condition Record
Polysaccharide, storage of unusual

Recent clinical studies

Etiology

Revisiting antithrombin in health and disease, congenital deficiencies and genetic variants, and laboratory studies on α and β forms.
Amiral J, Seghatchian J
Transfus Apher Sci 2018 Apr;57(2):291-297. Epub 2018 Apr 19 doi: 10.1016/j.transci.2018.04.010. PMID: 29784539
Natural Antibodies Against Sialoglycans.
Shilova N, Huflejt ME, Vuskovic M, Obukhova P, Navakouski M, Khasbiullina N, Pazynina G, Galanina O, Bazhenov A, Bovin N
Top Curr Chem 2015;366:169-81. doi: 10.1007/128_2013_469. PMID: 24037491
Standardized protocol for artery-only fingertip replantation.
Buntic RF, Brooks D
J Hand Surg Am 2010 Sep;35(9):1491-6. doi: 10.1016/j.jhsa.2010.06.004. PMID: 20807626
Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters.
Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N
Clin Endocrinol (Oxf) 2001 Apr;54(4):447-53. doi: 10.1046/j.1365-2265.2001.01228.x. PMID: 11318779
Mechanisms of hepatic chylomicron remnant clearance.
Willnow TE
Diabet Med 1997 Aug;14 Suppl 3:S75-80. doi: 10.1002/(sici)1096-9136(199708)14:3+<s75::aid-dia449>3.3.co;2-0. PMID: 9272618

Diagnosis

Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1).
Bayarri-Olmos R, Kirketerp-Moller N, Pérez-Alós L, Skjodt K, Skjoedt MO, Garred P
Front Immunol 2018;9:2238. Epub 2018 Sep 28 doi: 10.3389/fimmu.2018.02238. PMID: 30323815Free PMC Article
Revisiting antithrombin in health and disease, congenital deficiencies and genetic variants, and laboratory studies on α and β forms.
Amiral J, Seghatchian J
Transfus Apher Sci 2018 Apr;57(2):291-297. Epub 2018 Apr 19 doi: 10.1016/j.transci.2018.04.010. PMID: 29784539
Natural Antibodies Against Sialoglycans.
Shilova N, Huflejt ME, Vuskovic M, Obukhova P, Navakouski M, Khasbiullina N, Pazynina G, Galanina O, Bazhenov A, Bovin N
Top Curr Chem 2015;366:169-81. doi: 10.1007/128_2013_469. PMID: 24037491
Apparent argatroban resistance in a patient with elevated factor VIII levels.
Kennedy DM, Alaniz C
Ann Pharmacother 2013 Jul-Aug;47(7-8):e29. Epub 2013 Jun 4 doi: 10.1345/aph.1R745. PMID: 23737512
Control of glycaemia.
Gerich JE
Baillieres Clin Endocrinol Metab 1993 Jul;7(3):551-86. doi: 10.1016/s0950-351x(05)80207-1. PMID: 8379904

Therapy

Revisiting antithrombin in health and disease, congenital deficiencies and genetic variants, and laboratory studies on α and β forms.
Amiral J, Seghatchian J
Transfus Apher Sci 2018 Apr;57(2):291-297. Epub 2018 Apr 19 doi: 10.1016/j.transci.2018.04.010. PMID: 29784539
Standardized protocol for artery-only fingertip replantation.
Buntic RF, Brooks D
J Hand Surg Am 2010 Sep;35(9):1491-6. doi: 10.1016/j.jhsa.2010.06.004. PMID: 20807626
Indirect evidence of hormone abuse. Proof of doping?
Minuto F, Barreca A, Melioli G
J Endocrinol Invest 2003 Sep;26(9):919-23. doi: 10.1007/BF03345244. PMID: 14964446
Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism.
Packard CJ, Shepherd J, Lindsay GM, Gaw A, Taskinen MR
J Clin Endocrinol Metab 1993 May;76(5):1209-16. doi: 10.1210/jcem.76.5.8496312. PMID: 8496312
Kinetic and functional studies of platelets, fibrinogen, and plasminogen in patients with hepatic cirrhosis.
Stein SF, Harker LA
J Lab Clin Med 1982 Feb;99(2):217-30. PMID: 7061918

Prognosis

Antihuman CD44 antibody BJ18 inhibits platelet phagocytosis by correcting aberrant FcɣR expression and M1 polarization in immune thrombocytopenia.
Sun L, Li L, Sun T, Zhang L, Li C, Xu M, Hou Y, Peng J, Hou M, Wang L
Int Immunopharmacol 2021 Jun;95:107502. Epub 2021 Mar 6 doi: 10.1016/j.intimp.2021.107502. PMID: 33690000
Impact of Heparin- or Nonheparin-Coated Circuits on Platelet Function in Pediatric Cardiac Surgery.
Giorni C, Pezzella C, Bojan M, Ricci Z, Pouard P, Raisky O, Tourneur L, La Salvia O, Favia I, Borgel D, Cogo P, Carotti A, Lasne D
Ann Thorac Surg 2019 Apr;107(4):1241-1247. Epub 2018 Nov 3 doi: 10.1016/j.athoracsur.2018.09.032. PMID: 30395857
Standardized protocol for artery-only fingertip replantation.
Buntic RF, Brooks D
J Hand Surg Am 2010 Sep;35(9):1491-6. doi: 10.1016/j.jhsa.2010.06.004. PMID: 20807626
Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters.
Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N
Clin Endocrinol (Oxf) 2001 Apr;54(4):447-53. doi: 10.1046/j.1365-2265.2001.01228.x. PMID: 11318779
Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis.
Calvano SE, Thompson WA, Marra MN, Coyle SM, de Riesthal HF, Trousdale RK, Barie PS, Scott RW, Moldawer LL, Lowry SF
Arch Surg 1994 Feb;129(2):220-6. doi: 10.1001/archsurg.1994.01420260116016. PMID: 7508221

Clinical prediction guides

Antihuman CD44 antibody BJ18 inhibits platelet phagocytosis by correcting aberrant FcɣR expression and M1 polarization in immune thrombocytopenia.
Sun L, Li L, Sun T, Zhang L, Li C, Xu M, Hou Y, Peng J, Hou M, Wang L
Int Immunopharmacol 2021 Jun;95:107502. Epub 2021 Mar 6 doi: 10.1016/j.intimp.2021.107502. PMID: 33690000
Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1).
Bayarri-Olmos R, Kirketerp-Moller N, Pérez-Alós L, Skjodt K, Skjoedt MO, Garred P
Front Immunol 2018;9:2238. Epub 2018 Sep 28 doi: 10.3389/fimmu.2018.02238. PMID: 30323815Free PMC Article
Natural Antibodies Against Sialoglycans.
Shilova N, Huflejt ME, Vuskovic M, Obukhova P, Navakouski M, Khasbiullina N, Pazynina G, Galanina O, Bazhenov A, Bovin N
Top Curr Chem 2015;366:169-81. doi: 10.1007/128_2013_469. PMID: 24037491
Indirect evidence of hormone abuse. Proof of doping?
Minuto F, Barreca A, Melioli G
J Endocrinol Invest 2003 Sep;26(9):919-23. doi: 10.1007/BF03345244. PMID: 14964446
Kinetic and functional studies of platelets, fibrinogen, and plasminogen in patients with hepatic cirrhosis.
Stein SF, Harker LA
J Lab Clin Med 1982 Feb;99(2):217-30. PMID: 7061918

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