Increased proportion of central memory CD4-positive, alpha-beta T cells

MedGen UID:: 1686342
•Concept ID:: C5139554
•: Finding

Synonyms:	Elevated proportion central memory CD4-positive, alpha-beta T cells; Elevated proportion of CD4+ central memory cells; Increased proportion of CD4+ central memory cells; Increased proportion of central memory CD4+, alpha-beta T cell

HPO:	HP:0410393

Definition

An abnormally elevated proportion of central memory CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. [from HPO]

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GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVIncreased proportion of central memory CD4-positive, alpha-beta T cells

Abnormal lymphocyte count
- Abnormal T cell count
  - Abnormal T cell subset distribution
    - Abnormal proportion of memory T cells
      - Abnormal proportion of CD4-positive, alpha-beta memory T cells
        Increased proportion of CD4-positive, alpha-beta memory T cells
        Increased proportion of central memory CD4-positive, alpha-beta T cells

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Increased proportion of central memory CD4-positive, alpha-beta T cells

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