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Increased urinary galactosylated oligosaccharide

MedGen UID:
1691812
•Concept ID:
C5139511
•
Finding
Synonym: Increased concentration of galactosylated oligosaccharides in urine
 
HPO: HP:0410346

Definition

An abnormal increase in the concentration of galactosylated oligosaccharides in urine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased urinary galactosylated oligosaccharide

Recent clinical studies

Etiology

Effects of infliximab therapy on biological markers of synovium activity and cartilage breakdown in patients with rheumatoid arthritis.
Marotte H, Gineyts E, Miossec P, Delmas PD
Ann Rheum Dis 2009 Jul;68(7):1197-200. Epub 2008 Aug 19 doi: 10.1136/ard.2008.096057. PMID: 18713784
Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation.
Bühler L, Yamada K, Kitamura H, Alwayn IP, Basker M, Appel JZ 3rd, Colvin RB, White-Scharf ME, Sachs DH, Robson SC, Awwad M, Cooper DK
Transplantation 2001 Dec 15;72(11):1743-52. doi: 10.1097/00007890-200112150-00007. PMID: 11740383
Adenovirus-mediated expression of human secretor type alpha(1,2) fucosyltransferase reduces level of Gal alpha(1,3)Gal epitope.
Xing L, Xia GH, Fei J, Bai XF, Guo LH
Acta Pharmacol Sin 2000 Sep;21(9):807-13. PMID: 11501162
Blocking of human anti-pig xenoantibodies by soluble GAL alpha 1-3Gal and Gal alpha 1-2Gal disaccharides; studies in a pig kidney in vitro perfusion model.
Magnusson S, Strokan V, Mölne J, Nilsson K, Rydberg L, Breimer ME
Transpl Int 2000;13(6):402-12. doi: 10.1007/s001470050722. PMID: 11140238
Aberrant glycosylation of IgA from patients with IgA nephropathy.
Baharaki D, Dueymes M, Perrichot R, Basset C, Le Corre R, Clèdes J, Youinou P
Glycoconj J 1996 Aug;13(4):505-11. doi: 10.1007/BF00731436. PMID: 8872105

Diagnosis

Diagnosis of subtypes of GM1 gangliosidosis in vitro and in vivo--using urinary oligosaccharides as substrates.
Takahashi Y, Orii T
Clin Chim Acta 1989 Feb 22;179(3):219-27. doi: 10.1016/0009-8981(89)90084-3. PMID: 2496942

Therapy

Effects of infliximab therapy on biological markers of synovium activity and cartilage breakdown in patients with rheumatoid arthritis.
Marotte H, Gineyts E, Miossec P, Delmas PD
Ann Rheum Dis 2009 Jul;68(7):1197-200. Epub 2008 Aug 19 doi: 10.1136/ard.2008.096057. PMID: 18713784

Clinical prediction guides

Effects of infliximab therapy on biological markers of synovium activity and cartilage breakdown in patients with rheumatoid arthritis.
Marotte H, Gineyts E, Miossec P, Delmas PD
Ann Rheum Dis 2009 Jul;68(7):1197-200. Epub 2008 Aug 19 doi: 10.1136/ard.2008.096057. PMID: 18713784
Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation.
Bühler L, Yamada K, Kitamura H, Alwayn IP, Basker M, Appel JZ 3rd, Colvin RB, White-Scharf ME, Sachs DH, Robson SC, Awwad M, Cooper DK
Transplantation 2001 Dec 15;72(11):1743-52. doi: 10.1097/00007890-200112150-00007. PMID: 11740383
Blocking of human anti-pig xenoantibodies by soluble GAL alpha 1-3Gal and Gal alpha 1-2Gal disaccharides; studies in a pig kidney in vitro perfusion model.
Magnusson S, Strokan V, Mölne J, Nilsson K, Rydberg L, Breimer ME
Transpl Int 2000;13(6):402-12. doi: 10.1007/s001470050722. PMID: 11140238
Aberrant glycosylation of IgA from patients with IgA nephropathy.
Baharaki D, Dueymes M, Perrichot R, Basset C, Le Corre R, Clèdes J, Youinou P
Glycoconj J 1996 Aug;13(4):505-11. doi: 10.1007/BF00731436. PMID: 8872105

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