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Decreased proportion of central memory CD4-positive, alpha-beta T cells

MedGen UID:
1697420
•Concept ID:
C5139549
•
Finding
Synonyms: Decreased proportion of CD4+ central memory cells; Decreased proportion of CD4-positive central memory cells; Decreased proportion of central memory CD4+, alpha-beta T cell; Reduced proportion of CD4+ central memory cells
 
HPO: HP:0410388

Definition

A reduced proportion of central memory CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased proportion of central memory CD4-positive, alpha-beta T cells

Conditions with this feature

Immunodeficiency 37
MedGen UID:
863632
•Concept ID:
C4015195
•
Disease or Syndrome
Any primary immunodeficiency disease in which the cause of the disease is a mutation in the BCL10 gene.
See: Condition Record
Immunodeficiency 37

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