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Cribriform Adenocarcinoma of Minor Salivary Gland

MedGen UID:
1701248
•Concept ID:
C5205693
•
Neoplastic Process

Definition

A minor salivary gland adenocarcinoma characterized by a cribriform pattern. It often metastasizes to the neck lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCribriform Adenocarcinoma of Minor Salivary Gland

Professional guidelines

PubMed

The Role of Molecular Testing in the Differential Diagnosis of Salivary Gland Carcinomas.
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877

Recent clinical studies

Etiology

Salivary gland polymorphous adenocarcinoma: Clinicopathological features and gene alterations in 36 Japanese patients.
Fukumura M, Ishibashi K, Nakaguro M, Nagao T, Saida K, Urano M, Tanigawa M, Hirai H, Yagyuu T, Kikuchi K, Yada N, Sugita Y, Miyabe M, Hasegawa S, Goto M, Yamamoto H, Ohuchi T, Kusafuka K, Ogawa I, Suzuki H, Notohara K, Shimoda M, Tada Y, Kirita T, Takata T, Morinaga S, Maeda H, Warnakulasuriya S, Miyabe S, Nagao T
J Oral Pathol Med 2022 Sep;51(8):710-720. Epub 2022 Aug 15 doi: 10.1111/jop.13336. PMID: 35880805
Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis.
Cantù G
Acta Otorhinolaryngol Ital 2021 Jun;41(3):206-214. doi: 10.14639/0392-100X-N1379. PMID: 34264913Free PMC Article
Polymorphous adenocarcinoma of salivary glands.
Mimica X, Katabi N, McGill MR, Hay A, Zanoni DK, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2019 Aug;95:52-58. Epub 2019 Jun 7 doi: 10.1016/j.oraloncology.2019.06.002. PMID: 31345394Free PMC Article
The Role of Molecular Testing in the Differential Diagnosis of Salivary Gland Carcinomas.
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877
Newly Described Entities in Salivary Gland Pathology.
Skálová A, Gnepp DR, Lewis JS Jr, Hunt JL, Bishop JA, Hellquist H, Rinaldo A, Vander Poorten V, Ferlito A
Am J Surg Pathol 2017 Aug;41(8):e33-e47. doi: 10.1097/PAS.0000000000000883. PMID: 28614209

Diagnosis

Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis.
Cantù G
Acta Otorhinolaryngol Ital 2021 Jun;41(3):206-214. doi: 10.14639/0392-100X-N1379. PMID: 34264913Free PMC Article
Polymorphous Adenocarcinoma.
Katabi N, Xu B
Surg Pathol Clin 2021 Mar;14(1):127-136. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.011. PMID: 33526217Free PMC Article
Historical Evolution of the Polymorphous Adenocarcinoma.
Hernandez-Prera JC
Head Neck Pathol 2019 Sep;13(3):415-422. Epub 2018 Sep 5 doi: 10.1007/s12105-018-0964-9. PMID: 30187348Free PMC Article
Polymorphous adenocarcinoma of the salivary glands: reappraisal and update.
Vander Poorten V, Triantafyllou A, Skálová A, Stenman G, Bishop JA, Hauben E, Hunt JL, Hellquist H, Feys S, De Bree R, Mäkitie AA, Quer M, Strojan P, Guntinas-Lichius O, Rinaldo A, Ferlito A
Eur Arch Otorhinolaryngol 2018 Jul;275(7):1681-1695. Epub 2018 May 14 doi: 10.1007/s00405-018-4985-5. PMID: 29761209
Salivary Gland Tumors: Current Concepts and Controversies.
Seethala RR
Surg Pathol Clin 2017 Mar;10(1):155-176. doi: 10.1016/j.path.2016.11.004. PMID: 28153132

Therapy

Management of adenoid cystic carcinoma of the head and neck: a single-institute study with over 25-year follow-up.
Ishida E, Ogawa T, Rokugo M, Ishikawa T, Wakamori S, Ohkoshi A, Usubuchi H, Higashi K, Ishii R, Nakanome A, Katori Y
Head Face Med 2020 Jul 2;16(1):14. doi: 10.1186/s13005-020-00226-2. PMID: 32616049Free PMC Article
Bilateral intraosseous adenoid cystic carcinoma of the mandible: report of a case with lung metastases at first clinical presentation.
Capodiferro S, Scully C, Macaita MG, Lo Muzio L, Favia G, Mairoano E
Oral Dis 2005 Mar;11(2):109-12. doi: 10.1111/j.1601-0825.2004.01060.x. PMID: 15752085
Signet-ring cell (mucin-producing) adenocarcinomas of minor salivary glands.
Ghannoum JE, Freedman PD
Am J Surg Pathol 2004 Jan;28(1):89-93. doi: 10.1097/00000478-200401000-00010. PMID: 14707869
A qualitative and quantitative electronmicroscopic study of the structure of the adenoid cystic carcinoma of human minor salivary glands.
Chisholm DM, Waterhouse JP, Kraucunas E, Sciubba JJ
J Oral Pathol 1975 Oct;4(3):103-19. doi: 10.1111/j.1600-0714.1975.tb01859.x. PMID: 171355

Prognosis

Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis.
Cantù G
Acta Otorhinolaryngol Ital 2021 Jun;41(3):206-214. doi: 10.14639/0392-100X-N1379. PMID: 34264913Free PMC Article
Polymorphous Adenocarcinoma.
Katabi N, Xu B
Surg Pathol Clin 2021 Mar;14(1):127-136. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.011. PMID: 33526217Free PMC Article
Polymorphous adenocarcinoma of salivary glands.
Mimica X, Katabi N, McGill MR, Hay A, Zanoni DK, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2019 Aug;95:52-58. Epub 2019 Jun 7 doi: 10.1016/j.oraloncology.2019.06.002. PMID: 31345394Free PMC Article
Polymorphous adenocarcinoma of the salivary glands: reappraisal and update.
Vander Poorten V, Triantafyllou A, Skálová A, Stenman G, Bishop JA, Hauben E, Hunt JL, Hellquist H, Feys S, De Bree R, Mäkitie AA, Quer M, Strojan P, Guntinas-Lichius O, Rinaldo A, Ferlito A
Eur Arch Otorhinolaryngol 2018 Jul;275(7):1681-1695. Epub 2018 May 14 doi: 10.1007/s00405-018-4985-5. PMID: 29761209
Salivary Gland Tumors: Current Concepts and Controversies.
Seethala RR
Surg Pathol Clin 2017 Mar;10(1):155-176. doi: 10.1016/j.path.2016.11.004. PMID: 28153132

Clinical prediction guides

Cribriform adenocarcinoma of the tongue and minor salivary glands: a systematic review of an uncommon clinicopathological entity.
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340
Polymorphous adenocarcinoma of salivary glands.
Mimica X, Katabi N, McGill MR, Hay A, Zanoni DK, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2019 Aug;95:52-58. Epub 2019 Jun 7 doi: 10.1016/j.oraloncology.2019.06.002. PMID: 31345394Free PMC Article
The Role of Molecular Testing in the Differential Diagnosis of Salivary Gland Carcinomas.
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877
Cribriform adenocarcinoma of the tongue and minor salivary glands: a review.
Michal M, Kacerovska D, Kazakov DV
Head Neck Pathol 2013 Jul;7 Suppl 1(Suppl 1):S3-11. Epub 2013 Jul 3 doi: 10.1007/s12105-013-0457-9. PMID: 23821209Free PMC Article
Advances in salivary gland pathology.
Cheuk W, Chan JK
Histopathology 2007 Jul;51(1):1-20. Epub 2007 May 31 doi: 10.1111/j.1365-2559.2007.02719.x. PMID: 17539914

Recent systematic reviews

Cribriform adenocarcinoma of the tongue and minor salivary glands: a systematic review of an uncommon clinicopathological entity.
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340

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