Decreased proportion of effector memory CD8-positive, alpha-beta T cells

MedGen UID:: 1703336
•Concept ID:: C5139551
•: Finding

HPO:	HP:0410390

Definition

A reduced proportion of CD8-positive, alpha-beta effector memory T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. [from HPO]

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GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDecreased proportion of effector memory CD8-positive, alpha-beta T cells

Abnormal lymphocyte count
- Abnormal T cell count
  - Abnormal T cell subset distribution
    - Abnormal proportion of memory T cells
      - Decreased proportion of memory T cells
        Decreased proportion of CD8-positive, alpha-beta memory T cells
        Decreased proportion of effector memory CD8-positive, alpha-beta T cells

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Decreased proportion of effector memory CD8-positive, alpha-beta T cells

Definition

Term Hierarchy

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