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Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type

MedGen UID:
1706089
Concept ID:
C5205066
Neoplastic Process
Synonyms: Refractory Diffuse Large B-Cell Lymphoma Non-GC/ABC; Refractory Diffuse Large B-Cell Lymphoma Non-Germinal Center/Activated B-Cell Type; Refractory Non-GC/ABC DLBCL

Definition

Diffuse large B-cell lymphoma activated B-cell type that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type

Professional guidelines

PubMed

Susanibar-Adaniya S, Barta SK
Am J Hematol 2021 May 1;96(5):617-629. Epub 2021 Mar 19 doi: 10.1002/ajh.26151. PMID: 33661537Free PMC Article
Ali S, Kjeken R, Niederlaender C, Markey G, Saunders TS, Opsata M, Moltu K, Bremnes B, Grønevik E, Muusse M, Håkonsen GD, Skibeli V, Kalland ME, Wang I, Buajordet I, Urbaniak A, Johnston J, Rantell K, Kerwash E, Schuessler-Lenz M, Salmonson T, Bergh J, Gisselbrecht C, Tzogani K, Papadouli I, Pignatti F
Oncologist 2020 Feb;25(2):e321-e327. Epub 2019 Oct 16 doi: 10.1634/theoncologist.2019-0233. PMID: 32043764Free PMC Article
Wilson WH, Hernandez-Ilizaliturri FJ, Dunleavy K, Little RF, O'Connor OA
Leuk Lymphoma 2010 Aug;51 Suppl 1(Suppl 1):1-10. doi: 10.3109/10428194.2010.500045. PMID: 20658952Free PMC Article

Recent clinical studies

Etiology

Xu B
Eur J Clin Pharmacol 2022 May;78(5):707-719. Epub 2022 Jan 21 doi: 10.1007/s00228-021-03253-3. PMID: 35061047
Kraft RM, Ansell SM, Villasboas JC, Bennani NN, Wang Y, Habermann TM, Thanarajasingam G, Lester SC, Macon W, Inwards DJ, Porrata LF, Micallef IN, Witzig TE, Thompson CA, Johnston PB, Nowakowski GS, Lin Y, Paludo J
Hematol Oncol 2021 Dec;39(5):658-663. Epub 2021 Aug 28 doi: 10.1002/hon.2919. PMID: 34453851
Susanibar-Adaniya S, Barta SK
Am J Hematol 2021 May 1;96(5):617-629. Epub 2021 Mar 19 doi: 10.1002/ajh.26151. PMID: 33661537Free PMC Article
Sun F, Fang X, Wang X
Anticancer Agents Med Chem 2019;19(17):2047-2059. doi: 10.2174/1871520619666190925143216. PMID: 32009599
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716

Diagnosis

Shi Y, Ding W, Gu W, Shen Y, Li H, Zheng Z, Zheng X, Liu Y, Ling Y
J Leukoc Biol 2022 Dec;112(6):1633-1648. Epub 2022 Aug 30 doi: 10.1002/JLB.6MA0822-720RR. PMID: 36040107
Kraft RM, Ansell SM, Villasboas JC, Bennani NN, Wang Y, Habermann TM, Thanarajasingam G, Lester SC, Macon W, Inwards DJ, Porrata LF, Micallef IN, Witzig TE, Thompson CA, Johnston PB, Nowakowski GS, Lin Y, Paludo J
Hematol Oncol 2021 Dec;39(5):658-663. Epub 2021 Aug 28 doi: 10.1002/hon.2919. PMID: 34453851
Sun F, Fang X, Wang X
Anticancer Agents Med Chem 2019;19(17):2047-2059. doi: 10.2174/1871520619666190925143216. PMID: 32009599
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716
Wilson WH, Hernandez-Ilizaliturri FJ, Dunleavy K, Little RF, O'Connor OA
Leuk Lymphoma 2010 Aug;51 Suppl 1(Suppl 1):1-10. doi: 10.3109/10428194.2010.500045. PMID: 20658952Free PMC Article

Therapy

Kraft RM, Ansell SM, Villasboas JC, Bennani NN, Wang Y, Habermann TM, Thanarajasingam G, Lester SC, Macon W, Inwards DJ, Porrata LF, Micallef IN, Witzig TE, Thompson CA, Johnston PB, Nowakowski GS, Lin Y, Paludo J
Hematol Oncol 2021 Dec;39(5):658-663. Epub 2021 Aug 28 doi: 10.1002/hon.2919. PMID: 34453851
Susanibar-Adaniya S, Barta SK
Am J Hematol 2021 May 1;96(5):617-629. Epub 2021 Mar 19 doi: 10.1002/ajh.26151. PMID: 33661537Free PMC Article
Harris LJ, Patel K, Martin M
Int J Mol Sci 2020 Nov 13;21(22) doi: 10.3390/ijms21228553. PMID: 33202794Free PMC Article
Katoh M, Katoh M
Int J Mol Med 2020 Feb;45(2):279-297. Epub 2019 Dec 4 doi: 10.3892/ijmm.2019.4418. PMID: 31894255Free PMC Article
López A, Gutiérrez A, Palacios A, Blancas I, Navarrete M, Morey M, Perelló A, Alarcón J, Martínez J, Rodríguez J
Eur J Haematol 2008 Feb;80(2):127-32. Epub 2007 Nov 20 doi: 10.1111/j.1600-0609.2007.00996.x. PMID: 18005385

Prognosis

Shi Y, Ding W, Gu W, Shen Y, Li H, Zheng Z, Zheng X, Liu Y, Ling Y
J Leukoc Biol 2022 Dec;112(6):1633-1648. Epub 2022 Aug 30 doi: 10.1002/JLB.6MA0822-720RR. PMID: 36040107
Kraft RM, Ansell SM, Villasboas JC, Bennani NN, Wang Y, Habermann TM, Thanarajasingam G, Lester SC, Macon W, Inwards DJ, Porrata LF, Micallef IN, Witzig TE, Thompson CA, Johnston PB, Nowakowski GS, Lin Y, Paludo J
Hematol Oncol 2021 Dec;39(5):658-663. Epub 2021 Aug 28 doi: 10.1002/hon.2919. PMID: 34453851
Sun F, Fang X, Wang X
Anticancer Agents Med Chem 2019;19(17):2047-2059. doi: 10.2174/1871520619666190925143216. PMID: 32009599
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716
López A, Gutiérrez A, Palacios A, Blancas I, Navarrete M, Morey M, Perelló A, Alarcón J, Martínez J, Rodríguez J
Eur J Haematol 2008 Feb;80(2):127-32. Epub 2007 Nov 20 doi: 10.1111/j.1600-0609.2007.00996.x. PMID: 18005385

Clinical prediction guides

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J
Blood Adv 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. PMID: 35947123Free PMC Article
Shi Y, Ding W, Gu W, Shen Y, Li H, Zheng Z, Zheng X, Liu Y, Ling Y
J Leukoc Biol 2022 Dec;112(6):1633-1648. Epub 2022 Aug 30 doi: 10.1002/JLB.6MA0822-720RR. PMID: 36040107
Kraft RM, Ansell SM, Villasboas JC, Bennani NN, Wang Y, Habermann TM, Thanarajasingam G, Lester SC, Macon W, Inwards DJ, Porrata LF, Micallef IN, Witzig TE, Thompson CA, Johnston PB, Nowakowski GS, Lin Y, Paludo J
Hematol Oncol 2021 Dec;39(5):658-663. Epub 2021 Aug 28 doi: 10.1002/hon.2919. PMID: 34453851
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716
López A, Gutiérrez A, Palacios A, Blancas I, Navarrete M, Morey M, Perelló A, Alarcón J, Martínez J, Rodríguez J
Eur J Haematol 2008 Feb;80(2):127-32. Epub 2007 Nov 20 doi: 10.1111/j.1600-0609.2007.00996.x. PMID: 18005385

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