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Chemotherapy-related Cognitive Impairment

MedGen UID:
1709769
Concept ID:
C5392105
Mental or Behavioral Dysfunction
Synonyms: Chemo Fog; Chemo-Fog; Chemobrain; Chemotherapy Induced Cognitive Dysfunction; Chemotherapy Induced Cognitive Impairment; Chemotherapy Induced Cognitive Impairments; Chemotherapy Related Cognitive Dysfunction; Chemotherapy Related Cognitive Impairment; Chemotherapy-Induced Cognitive Dysfunction; Chemotherapy-Induced Cognitive Impairment; Chemotherapy-Induced Cognitive Impairments; Chemotherapy-Related Cognitive Dysfunction; Chemotherapy-Related Cognitive Dysfunctions; Chemotherapy-Related Cognitive Impairment; Chemotherapy-Related Cognitive Impairments; Cognitive Dysfunction, Chemotherapy-Induced; Cognitive Dysfunction, Chemotherapy-Related; Cognitive Impairment, Chemotherapy-Induced; Cognitive Impairment, Chemotherapy-Related; Cognitive Impairments, Chemotherapy-Induced; Cognitive Impairments, Chemotherapy-Related

Definition

Diminished mental function after chemotherapy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChemotherapy-related Cognitive Impairment

Professional guidelines

PubMed

Chung NC, Walker AK, Dhillon HM, Vardy JL
Oncology (Williston Park) 2018 Dec 17;32(12):591-8. PMID: 30632128
Dwek MR, Rixon L, Hurt C, Simon A, Newman S
Psychooncology 2017 Oct;26(10):1422-1432. Epub 2017 Feb 20 doi: 10.1002/pon.4331. PMID: 27893174
Craig CD, Monk BJ, Farley JH, Chase DM
Support Care Cancer 2014 Jan;22(1):279-87. Epub 2013 Nov 10 doi: 10.1007/s00520-013-2029-7. PMID: 24212261

Recent clinical studies

Etiology

Rao V, Bhushan R, Kumari P, Cheruku SP, Ravichandiran V, Kumar N
Adv Cancer Res 2022;155:29-76. Epub 2022 May 11 doi: 10.1016/bs.acr.2022.04.001. PMID: 35779876
Juan Z, Chen J, Ding B, Yongping L, Liu K, Wang L, Le Y, Liao Q, Shi J, Huang J, Wu Y, Ma D, Ouyang W, Tong J
Eur J Cancer 2022 Jan;161:10-22. Epub 2021 Dec 9 doi: 10.1016/j.ejca.2021.11.006. PMID: 34896904
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Eide S, Feng ZP
Eur J Pharmacol 2020 Aug 15;881:173078. Epub 2020 Jun 5 doi: 10.1016/j.ejphar.2020.173078. PMID: 32505665
Myers JS
Clin J Oncol Nurs 2009 Aug;13(4):413-21. doi: 10.1188/09.CJON.413-421. PMID: 19648097

Diagnosis

Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Eide S, Feng ZP
Eur J Pharmacol 2020 Aug 15;881:173078. Epub 2020 Jun 5 doi: 10.1016/j.ejphar.2020.173078. PMID: 32505665
Cascella M, Di Napoli R, Carbone D, Cuomo GF, Bimonte S, Muzio MR
Recenti Prog Med 2018 Nov;109(11):523-530. doi: 10.1701/3031.30289. PMID: 30565571
Vega JN, Dumas J, Newhouse PA
Am J Geriatr Psychiatry 2017 Dec;25(12):1415-1426. Epub 2017 Apr 6 doi: 10.1016/j.jagp.2017.04.001. PMID: 28495470Free PMC Article
Myers JS
Clin J Oncol Nurs 2009 Aug;13(4):413-21. doi: 10.1188/09.CJON.413-421. PMID: 19648097

Therapy

Juan Z, Chen J, Ding B, Yongping L, Liu K, Wang L, Le Y, Liao Q, Shi J, Huang J, Wu Y, Ma D, Ouyang W, Tong J
Eur J Cancer 2022 Jan;161:10-22. Epub 2021 Dec 9 doi: 10.1016/j.ejca.2021.11.006. PMID: 34896904
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Geraghty AC, Gibson EM, Ghanem RA, Greene JJ, Ocampo A, Goldstein AK, Ni L, Yang T, Marton RM, Paşca SP, Greenberg ME, Longo FM, Monje M
Neuron 2019 Jul 17;103(2):250-265.e8. Epub 2019 May 20 doi: 10.1016/j.neuron.2019.04.032. PMID: 31122677Free PMC Article
Gibson EM, Nagaraja S, Ocampo A, Tam LT, Wood LS, Pallegar PN, Greene JJ, Geraghty AC, Goldstein AK, Ni L, Woo PJ, Barres BA, Liddelow S, Vogel H, Monje M
Cell 2019 Jan 10;176(1-2):43-55.e13. Epub 2018 Dec 6 doi: 10.1016/j.cell.2018.10.049. PMID: 30528430Free PMC Article
Cascella M, Di Napoli R, Carbone D, Cuomo GF, Bimonte S, Muzio MR
Recenti Prog Med 2018 Nov;109(11):523-530. doi: 10.1701/3031.30289. PMID: 30565571

Prognosis

Vega JN, Albert KM, Mayer IA, Taylor WD, Newhouse PA
J Cancer Surviv 2022 Jun;16(3):614-623. Epub 2021 May 11 doi: 10.1007/s11764-021-01055-1. PMID: 33973154Free PMC Article
Subramaniam CB, Bowen JM, Gladman MA, Lustberg MB, Mayo SJ, Wardill HR
Neurosci Biobehav Rev 2020 Sep;116:470-479. Epub 2020 Jul 15 doi: 10.1016/j.neubiorev.2020.07.002. PMID: 32681936
Kesler SR, Petersen ML, Rao V, Harrison RA, Palesh O
J Cancer Surviv 2020 Aug;14(4):483-493. Epub 2020 Mar 10 doi: 10.1007/s11764-020-00863-1. PMID: 32157609Free PMC Article
Allegra A, Innao V, Basile G, Pugliese M, Allegra AG, Pulvirenti N, Musolino C
Expert Rev Hematol 2020 Apr;13(4):393-404. Epub 2020 Mar 10 doi: 10.1080/17474086.2020.1738213. PMID: 32129131
Hutchinson AD, Hosking JR, Kichenadasse G, Mattiske JK, Wilson C
Cancer Treat Rev 2012 Nov;38(7):926-34. Epub 2012 Jun 2 doi: 10.1016/j.ctrv.2012.05.002. PMID: 22658913

Clinical prediction guides

Vega JN, Albert KM, Mayer IA, Taylor WD, Newhouse PA
J Cancer Surviv 2022 Jun;16(3):614-623. Epub 2021 May 11 doi: 10.1007/s11764-021-01055-1. PMID: 33973154Free PMC Article
Sekeres MJ, Bradley-Garcia M, Martinez-Canabal A, Winocur G
Int J Mol Sci 2021 Nov 24;22(23) doi: 10.3390/ijms222312697. PMID: 34884513Free PMC Article
Rummel NG, Chaiswing L, Bondada S, St Clair DK, Butterfield DA
Cell Mol Life Sci 2021 Oct;78(19-20):6533-6540. Epub 2021 Aug 23 doi: 10.1007/s00018-021-03925-4. PMID: 34424346Free PMC Article
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Allegra A, Innao V, Basile G, Pugliese M, Allegra AG, Pulvirenti N, Musolino C
Expert Rev Hematol 2020 Apr;13(4):393-404. Epub 2020 Mar 10 doi: 10.1080/17474086.2020.1738213. PMID: 32129131

Recent systematic reviews

Oldacres L, Hegarty J, O'Regan P, Murphy-Coakley NM, Saab MM
Psychooncology 2023 Feb;32(2):214-228. Epub 2022 Dec 14 doi: 10.1002/pon.6073. PMID: 36443527Free PMC Article
Whittaker AL, George RP, O'Malley L
Sci Rep 2022 Feb 8;12(1):2135. doi: 10.1038/s41598-022-05682-1. PMID: 35136066Free PMC Article
Dwek MR, Rixon L, Hurt C, Simon A, Newman S
Psychooncology 2017 Oct;26(10):1422-1432. Epub 2017 Feb 20 doi: 10.1002/pon.4331. PMID: 27893174
Craig CD, Monk BJ, Farley JH, Chase DM
Support Care Cancer 2014 Jan;22(1):279-87. Epub 2013 Nov 10 doi: 10.1007/s00520-013-2029-7. PMID: 24212261
Hutchinson AD, Hosking JR, Kichenadasse G, Mattiske JK, Wilson C
Cancer Treat Rev 2012 Nov;38(7):926-34. Epub 2012 Jun 2 doi: 10.1016/j.ctrv.2012.05.002. PMID: 22658913

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