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Chemotherapy-related Cognitive Impairment

MedGen UID:
1709769
Concept ID:
C5392105
Mental or Behavioral Dysfunction
Synonyms: Chemo Fog; Chemo-Fog; Chemobrain; Chemotherapy Induced Cognitive Dysfunction; Chemotherapy Induced Cognitive Impairment; Chemotherapy Induced Cognitive Impairments; Chemotherapy Related Cognitive Dysfunction; Chemotherapy Related Cognitive Impairment; Chemotherapy-Induced Cognitive Dysfunction; Chemotherapy-Induced Cognitive Impairment; Chemotherapy-Induced Cognitive Impairments; Chemotherapy-Related Cognitive Dysfunction; Chemotherapy-Related Cognitive Dysfunctions; Chemotherapy-Related Cognitive Impairment; Chemotherapy-Related Cognitive Impairments; Cognitive Dysfunction, Chemotherapy-Induced; Cognitive Dysfunction, Chemotherapy-Related; Cognitive Impairment, Chemotherapy-Induced; Cognitive Impairment, Chemotherapy-Related; Cognitive Impairments, Chemotherapy-Induced; Cognitive Impairments, Chemotherapy-Related

Definition

Diminished mental function after chemotherapy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChemotherapy-related Cognitive Impairment

Professional guidelines

PubMed

Chung NC, Walker AK, Dhillon HM, Vardy JL
Oncology (Williston Park) 2018 Dec 17;32(12):591-8. PMID: 30632128
Dwek MR, Rixon L, Hurt C, Simon A, Newman S
Psychooncology 2017 Oct;26(10):1422-1432. Epub 2017 Feb 20 doi: 10.1002/pon.4331. PMID: 27893174
Craig CD, Monk BJ, Farley JH, Chase DM
Support Care Cancer 2014 Jan;22(1):279-87. Epub 2013 Nov 10 doi: 10.1007/s00520-013-2029-7. PMID: 24212261

Recent clinical studies

Etiology

Rao V, Bhushan R, Kumari P, Cheruku SP, Ravichandiran V, Kumar N
Adv Cancer Res 2022;155:29-76. Epub 2022 May 11 doi: 10.1016/bs.acr.2022.04.001. PMID: 35779876
Juan Z, Chen J, Ding B, Yongping L, Liu K, Wang L, Le Y, Liao Q, Shi J, Huang J, Wu Y, Ma D, Ouyang W, Tong J
Eur J Cancer 2022 Jan;161:10-22. Epub 2021 Dec 9 doi: 10.1016/j.ejca.2021.11.006. PMID: 34896904
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Eide S, Feng ZP
Eur J Pharmacol 2020 Aug 15;881:173078. Epub 2020 Jun 5 doi: 10.1016/j.ejphar.2020.173078. PMID: 32505665
Schrauwen W, Van de Cavey J, Vingerhoets G, Vanheule S, Van den Broecke R, Denys H
J Int Neuropsychol Soc 2020 Sep;26(8):806-814. Epub 2020 Apr 21 doi: 10.1017/S1355617720000296. PMID: 32312360

Diagnosis

Yao S, Zhu Q, Zhang Q, Cai Y, Liu S, Pang L, Jing Y, Yin X, Cheng H
Cancer Med 2023 Aug;12(15):16231-16242. Epub 2023 Jul 6 doi: 10.1002/cam4.6285. PMID: 37409628Free PMC Article
Ouyang T, Kanekar S
Radiol Clin North Am 2021 May;59(3):425-440. Epub 2021 Mar 23 doi: 10.1016/j.rcl.2021.01.008. PMID: 33926687
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Eide S, Feng ZP
Eur J Pharmacol 2020 Aug 15;881:173078. Epub 2020 Jun 5 doi: 10.1016/j.ejphar.2020.173078. PMID: 32505665
Cascella M, Di Napoli R, Carbone D, Cuomo GF, Bimonte S, Muzio MR
Recenti Prog Med 2018 Nov;109(11):523-530. doi: 10.1701/3031.30289. PMID: 30565571

Therapy

Alexander JF, Seua AV, Arroyo LD, Ray PR, Wangzhou A, Heiβ-Lückemann L, Schedlowski M, Price TJ, Kavelaars A, Heijnen CJ
Theranostics 2021;11(7):3109-3130. Epub 2021 Jan 1 doi: 10.7150/thno.53474. PMID: 33537077Free PMC Article
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Geraghty AC, Gibson EM, Ghanem RA, Greene JJ, Ocampo A, Goldstein AK, Ni L, Yang T, Marton RM, Paşca SP, Greenberg ME, Longo FM, Monje M
Neuron 2019 Jul 17;103(2):250-265.e8. Epub 2019 May 20 doi: 10.1016/j.neuron.2019.04.032. PMID: 31122677Free PMC Article
Cascella M, Di Napoli R, Carbone D, Cuomo GF, Bimonte S, Muzio MR
Recenti Prog Med 2018 Nov;109(11):523-530. doi: 10.1701/3031.30289. PMID: 30565571
Kaiser J, Bledowski C, Dietrich J
Cortex 2014 May;54:33-50. Epub 2014 Jan 30 doi: 10.1016/j.cortex.2014.01.010. PMID: 24632463

Prognosis

Mulholland MM, Prinsloo S, Kvale E, Dula AN, Palesh O, Kesler SR
Brain Imaging Behav 2023 Jun;17(3):320-328. Epub 2023 May 2 doi: 10.1007/s11682-023-00774-6. PMID: 37127832Free PMC Article
Beesley VL, Ross TL, King MT, Campbell R, Nagle CM, Obermair A, Grant P, DeFazio A, Webb PM, Friedlander ML; OPAL Study Group
Gynecol Oncol 2022 Feb;164(2):437-445. Epub 2021 Dec 24 doi: 10.1016/j.ygyno.2021.12.006. PMID: 34955238
Vega JN, Albert KM, Mayer IA, Taylor WD, Newhouse PA
J Cancer Surviv 2022 Jun;16(3):614-623. Epub 2021 May 11 doi: 10.1007/s11764-021-01055-1. PMID: 33973154Free PMC Article
Kesler SR, Petersen ML, Rao V, Harrison RA, Palesh O
J Cancer Surviv 2020 Aug;14(4):483-493. Epub 2020 Mar 10 doi: 10.1007/s11764-020-00863-1. PMID: 32157609Free PMC Article
Allegra A, Innao V, Basile G, Pugliese M, Allegra AG, Pulvirenti N, Musolino C
Expert Rev Hematol 2020 Apr;13(4):393-404. Epub 2020 Mar 10 doi: 10.1080/17474086.2020.1738213. PMID: 32129131

Clinical prediction guides

Budamagunta V, Kumar A, Rani A, Manohar Sindhu S, Yang Y, Zhou D, Foster TC
Aging Cell 2024 Feb;23(2):e14037. Epub 2024 Jan 15 doi: 10.1111/acel.14037. PMID: 38225896Free PMC Article
Torre M, Bukhari H, Nithianandam V, Zanella CA, Mata DA, Feany MB
Sci Rep 2023 Nov 7;13(1):19290. doi: 10.1038/s41598-023-46616-9. PMID: 37935827Free PMC Article
Yao S, Zhu Q, Zhang Q, Cai Y, Liu S, Pang L, Jing Y, Yin X, Cheng H
Cancer Med 2023 Aug;12(15):16231-16242. Epub 2023 Jul 6 doi: 10.1002/cam4.6285. PMID: 37409628Free PMC Article
Rodríguez Martín B, Fernández Rodríguez EJ, Rihuete Galve MI, Cruz Hernández JJ
Int J Environ Res Public Health 2020 Nov 30;17(23) doi: 10.3390/ijerph17238896. PMID: 33265966Free PMC Article
Schrauwen W, Van de Cavey J, Vingerhoets G, Vanheule S, Van den Broecke R, Denys H
J Int Neuropsychol Soc 2020 Sep;26(8):806-814. Epub 2020 Apr 21 doi: 10.1017/S1355617720000296. PMID: 32312360

Recent systematic reviews

Zhou X, Zhang X, Zhong T, Zhou M, Gao L, Chen L
J Adv Nurs 2024 Feb;80(2):484-499. Epub 2023 Sep 7 doi: 10.1111/jan.15842. PMID: 37675947
Liu Y, Liu JE, Chen S, Zhao F, Chen L, Li R
Cancer Nurs 2023 Sep-Oct 01;46(5):E305-E319. Epub 2022 Dec 11 doi: 10.1097/NCC.0000000000001152. PMID: 37607381
Tyagi K, Masoom M, Majid H, Garg A, Bhurani D, Agarwal NB, Khan MA
Curr Rev Clin Exp Pharmacol 2023;18(2):110-119. doi: 10.2174/2772432817666220304212456. PMID: 35249524
Whittaker AL, George RP, O'Malley L
Sci Rep 2022 Feb 8;12(1):2135. doi: 10.1038/s41598-022-05682-1. PMID: 35136066Free PMC Article
Hutchinson AD, Hosking JR, Kichenadasse G, Mattiske JK, Wilson C
Cancer Treat Rev 2012 Nov;38(7):926-34. Epub 2012 Jun 2 doi: 10.1016/j.ctrv.2012.05.002. PMID: 22658913

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