U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Focal bilateral motor seizure

MedGen UID:
1710584
Concept ID:
C5397725
Disease or Syndrome
HPO: HP:0032715

Definition

A type of focal motor seizure (it commences in one hemisphere) involving bilateral muscle groups rapidly at seizure onset. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Pack AM, Oskoui M, Williams Roberson S, Donley DK, French J, Gerard EE, Gloss D, Miller WR, Munger Clary HM, Osmundson SS, McFadden B, Parratt K, Pennell PB, Saade G, Smith DB, Sullivan K, Thomas SV, Tomson T, Dolan O'Brien M, Botchway-Doe K, Silsbee HM, Keezer MR
Neurology 2024 Jun;102(11):e209279. Epub 2024 May 15 doi: 10.1212/WNL.0000000000209279. PMID: 38748979Free PMC Article
Martín-Jiménez P, Sánchez-Tornero M, Llamas-Velasco S, Guerrero-Molina MP, González-Sánchez M, Herrero-San Martín A, Blanco-Palmero V, Calleja-Castaño P, Francisco-Gonzalo J, Hilario A, Ramos A, Salvador E, Toldos Ó, Hernández-Lain A, Pérez-Martínez DA, Villarejo-Galende A
Neurologia (Engl Ed) 2023 Oct;38(8):550-559. Epub 2023 Jul 10 doi: 10.1016/j.nrleng.2023.07.002. PMID: 37437655
Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT
Epilepsy Behav 2022 Nov;136:108885. Epub 2022 Sep 21 doi: 10.1016/j.yebeh.2022.108885. PMID: 36150304

Recent clinical studies

Etiology

Nascimento FA, Friedman D, Peters JM, Bensalem-Owen MK, Cendes F, Rampp S, Wirrell E, Blümcke I, Tatum W, Beniczky S
Epileptic Disord 2023 Feb;25(1):1-17. Epub 2023 Apr 17 doi: 10.1002/epd2.20045. PMID: 36938903
Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT
Epilepsy Behav 2022 Nov;136:108885. Epub 2022 Sep 21 doi: 10.1016/j.yebeh.2022.108885. PMID: 36150304
Knight EMP, Amin S, Bahi-Buisson N, Benke TA, Cross JH, Demarest ST, Olson HE, Specchio N, Fleming TR, Aimetti AA, Gasior M, Devinsky O; Marigold Trial Group
Lancet Neurol 2022 May;21(5):417-427. doi: 10.1016/S1474-4422(22)00077-1. PMID: 35429480
Chung SS, French JA, Kowalski J, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Mizne S, Kamin M
Neurology 2020 Jun 2;94(22):e2311-e2322. Epub 2020 May 14 doi: 10.1212/WNL.0000000000009530. PMID: 32409485Free PMC Article
Krauss GL, Klein P, Brandt C, Lee SK, Milanov I, Milovanovic M, Steinhoff BJ, Kamin M
Lancet Neurol 2020 Jan;19(1):38-48. Epub 2019 Nov 14 doi: 10.1016/S1474-4422(19)30399-0. PMID: 31734103

Diagnosis

Nascimento FA, Friedman D, Peters JM, Bensalem-Owen MK, Cendes F, Rampp S, Wirrell E, Blümcke I, Tatum W, Beniczky S
Epileptic Disord 2023 Feb;25(1):1-17. Epub 2023 Apr 17 doi: 10.1002/epd2.20045. PMID: 36938903
Specchio N, Pietrafusa N
Dev Med Child Neurol 2020 Aug;62(8):897-905. Epub 2020 May 5 doi: 10.1111/dmcn.14553. PMID: 32372459
Pack AM
Continuum (Minneap Minn) 2019 Apr;25(2):306-321. doi: 10.1212/CON.0000000000000707. PMID: 30921011
Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshé SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM
Epilepsia 2017 Apr;58(4):522-530. Epub 2017 Mar 8 doi: 10.1111/epi.13670. PMID: 28276060
Berg AT, Berkovic SF, Brodie MJ, Buchhalter J, Cross JH, van Emde Boas W, Engel J, French J, Glauser TA, Mathern GW, Moshé SL, Nordli D, Plouin P, Scheffer IE
Epilepsia 2010 Apr;51(4):676-85. Epub 2010 Feb 26 doi: 10.1111/j.1528-1167.2010.02522.x. PMID: 20196795

Therapy

Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT
Epilepsy Behav 2022 Nov;136:108885. Epub 2022 Sep 21 doi: 10.1016/j.yebeh.2022.108885. PMID: 36150304
Knight EMP, Amin S, Bahi-Buisson N, Benke TA, Cross JH, Demarest ST, Olson HE, Specchio N, Fleming TR, Aimetti AA, Gasior M, Devinsky O; Marigold Trial Group
Lancet Neurol 2022 May;21(5):417-427. doi: 10.1016/S1474-4422(22)00077-1. PMID: 35429480
Krauss GL, Klein P, Brandt C, Lee SK, Milanov I, Milovanovic M, Steinhoff BJ, Kamin M
Lancet Neurol 2020 Jan;19(1):38-48. Epub 2019 Nov 14 doi: 10.1016/S1474-4422(19)30399-0. PMID: 31734103
Rugg-Gunn F, Miserocchi A, McEvoy A
Pract Neurol 2020 Feb;20(1):4-14. Epub 2019 Aug 16 doi: 10.1136/practneurol-2019-002192. PMID: 31420415
Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, Oommen K, Osorio I, Nazzaro J, Labar D, Kaplitt M, Sperling M, Sandok E, Neal J, Handforth A, Stern J, DeSalles A, Chung S, Shetter A, Bergen D, Bakay R, Henderson J, French J, Baltuch G, Rosenfeld W, Youkilis A, Marks W, Garcia P, Barbaro N, Fountain N, Bazil C, Goodman R, McKhann G, Babu Krishnamurthy K, Papavassiliou S, Epstein C, Pollard J, Tonder L, Grebin J, Coffey R, Graves N; SANTE Study Group
Epilepsia 2010 May;51(5):899-908. Epub 2010 Mar 17 doi: 10.1111/j.1528-1167.2010.02536.x. PMID: 20331461

Prognosis

Levine JM, Ahsan N, Ho E, Santoro JD
Mult Scler Relat Disord 2020 Aug;43:102194. Epub 2020 May 15 doi: 10.1016/j.msard.2020.102194. PMID: 32426208Free PMC Article
Specchio N, Pietrafusa N
Dev Med Child Neurol 2020 Aug;62(8):897-905. Epub 2020 May 5 doi: 10.1111/dmcn.14553. PMID: 32372459
Dulac O, Takahashi T
Handb Clin Neurol 2013;111:681-9. doi: 10.1016/B978-0-444-52891-9.00070-1. PMID: 23622215
Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, Oommen K, Osorio I, Nazzaro J, Labar D, Kaplitt M, Sperling M, Sandok E, Neal J, Handforth A, Stern J, DeSalles A, Chung S, Shetter A, Bergen D, Bakay R, Henderson J, French J, Baltuch G, Rosenfeld W, Youkilis A, Marks W, Garcia P, Barbaro N, Fountain N, Bazil C, Goodman R, McKhann G, Babu Krishnamurthy K, Papavassiliou S, Epstein C, Pollard J, Tonder L, Grebin J, Coffey R, Graves N; SANTE Study Group
Epilepsia 2010 May;51(5):899-908. Epub 2010 Mar 17 doi: 10.1111/j.1528-1167.2010.02536.x. PMID: 20331461
Brenner RP
Epilepsia 2002;43 Suppl 3:103-13. doi: 10.1046/j.1528-1157.43.s.3.9.x. PMID: 12060012

Clinical prediction guides

Liu RC, Sheu JN, Liu CS, Tsai JD
Acta Neurol Taiwan 2024 Mar 30;33(1):41-42. PMID: 37853548
Panza N, Bianchini C, Cetica V, Balestrini S, Barba C, Ferrari AR, Mei D, Parmeggiani L, Parrini E, Guerrini R
Epilepsia Open 2024 Feb;9(1):417-423. Epub 2023 Dec 15 doi: 10.1002/epi4.12843. PMID: 37805811Free PMC Article
Chang P, Xie H, Illapani VSP, You X, Anwar T, Pasupuleti A, Vu TA, Vezina LG, Gholipour T, Oluigbo CO, Zhang A, Gaillard WD, Cohen NT
Epilepsia 2023 Sep;64(9):2434-2442. Epub 2023 Jul 7 doi: 10.1111/epi.17700. PMID: 37349955Free PMC Article
Wu TQ, Kaboodvand N, McGinn RJ, Veit M, Davey Z, Datta A, Graber KD, Meador KJ, Fisher R, Buch V, Parvizi J
Brain 2023 Jul 3;146(7):2792-2802. doi: 10.1093/brain/awad121. PMID: 37137813Free PMC Article
Ferreira-Atuesta C, de Tisi J, McEvoy AW, Miserocchi A, Khoury J, Yardi R, Vegh DT, Butler J, Lee HJ, Deli-Peri V, Yao Y, Wang FP, Zhang XB, Shakhatreh L, Siriratnam P, Neal A, Sen A, Tristram M, Varghese E, Biney W, Gray WP, Peralta AR, Rainha-Campos A, Gonçalves-Ferreira AJC, Pimentel J, Arias JF, Terman S, Terziev R, Lamberink HJ, Braun KPJ, Otte WM, Rugg-Gunn FJ, Gonzalez W, Bentes C, Hamandi K, O'Brien TJ, Perucca P, Yao C, Burman RJ, Jehi L, Duncan JS, Sander JW, Koepp M, Galovic M
Brain 2023 Jun 1;146(6):2389-2398. doi: 10.1093/brain/awac437. PMID: 36415957

Recent systematic reviews

Rondão MBA, Hsu BRRHS, Centeno RS, de Aguiar PHP
Seizure 2023 Aug;110:58-68. Epub 2023 Jun 3 doi: 10.1016/j.seizure.2023.04.020. PMID: 37327751
Lavu A, Aboulatta L, Abou-Setta AM, Aloud B, Askin N, Rabbani R, Shouman W, Zarychanski R, Eltonsy S
Seizure 2022 Nov;102:54-60. Epub 2022 Sep 29 doi: 10.1016/j.seizure.2022.09.020. PMID: 36206645
Cutillo G, Tolba H, Hirsch LJ
Epilepsy Behav 2021 Apr;117:107815. Epub 2021 Feb 26 doi: 10.1016/j.yebeh.2021.107815. PMID: 33640562
Christie H, D'Souza W, Cook M, Seneviratne U
Epilepsy Behav 2021 Mar;116:107769. Epub 2021 Feb 5 doi: 10.1016/j.yebeh.2021.107769. PMID: 33556863
Beh SMJ, Cook MJ, D'Souza WJ
Epilepsy Behav 2016 Jul;60:33-41. Epub 2016 May 10 doi: 10.1016/j.yebeh.2016.04.015. PMID: 27176882

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...