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Focal bilateral motor seizure

MedGen UID:
1710584
Concept ID:
C5397725
Disease or Syndrome
HPO: HP:0032715

Definition

A type of focal motor seizure (it commences in one hemisphere) involving bilateral muscle groups rapidly at seizure onset. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Villani F, Cianci V, Di Bonaventura C, Di Gennaro G, Galimberti CA, Guerrini R, La Neve A, Mecarelli O, Pietrafusa N, Specchio N, Vigevano F, Perucca E
Expert Rev Neurother 2022 Nov-Dec;22(11-12):935-940. Epub 2023 Jan 24 doi: 10.1080/14737175.2023.2171291. PMID: 36662573
Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT
Epilepsy Behav 2022 Nov;136:108885. Epub 2022 Sep 21 doi: 10.1016/j.yebeh.2022.108885. PMID: 36150304
Arteaga-Rodríguez C, Menine-Kubis M, Teixeira-Arteaga CB, Hernández-Fustes OJ
Rev Neurol 2022 Jul 1;75(1):7-12. doi: 10.33588/rn.7501.2022036. PMID: 35765823Free PMC Article

Recent clinical studies

Etiology

Nascimento FA, Friedman D, Peters JM, Bensalem-Owen MK, Cendes F, Rampp S, Wirrell E, Blümcke I, Tatum W, Beniczky S
Epileptic Disord 2023 Feb;25(1):1-17. Epub 2023 Apr 17 doi: 10.1002/epd2.20045. PMID: 36938903
Peña-Ceballos J, Moloney PB, Munteanu T, Doyle M, Colleran N, Liggan B, Breen A, Murphy S, El-Naggar H, Widdess-Walsh P, Delanty N
Epilepsia 2023 May;64(5):1225-1235. Epub 2023 Feb 27 doi: 10.1111/epi.17549. PMID: 36790345
Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT
Epilepsy Behav 2022 Nov;136:108885. Epub 2022 Sep 21 doi: 10.1016/j.yebeh.2022.108885. PMID: 36150304
Knight EMP, Amin S, Bahi-Buisson N, Benke TA, Cross JH, Demarest ST, Olson HE, Specchio N, Fleming TR, Aimetti AA, Gasior M, Devinsky O; Marigold Trial Group
Lancet Neurol 2022 May;21(5):417-427. doi: 10.1016/S1474-4422(22)00077-1. PMID: 35429480
Krauss GL, Klein P, Brandt C, Lee SK, Milanov I, Milovanovic M, Steinhoff BJ, Kamin M
Lancet Neurol 2020 Jan;19(1):38-48. Epub 2019 Nov 14 doi: 10.1016/S1474-4422(19)30399-0. PMID: 31734103

Diagnosis

Nascimento FA, Friedman D, Peters JM, Bensalem-Owen MK, Cendes F, Rampp S, Wirrell E, Blümcke I, Tatum W, Beniczky S
Epileptic Disord 2023 Feb;25(1):1-17. Epub 2023 Apr 17 doi: 10.1002/epd2.20045. PMID: 36938903
Specchio N, Pietrafusa N
Dev Med Child Neurol 2020 Aug;62(8):897-905. Epub 2020 May 5 doi: 10.1111/dmcn.14553. PMID: 32372459
Pack AM
Continuum (Minneap Minn) 2019 Apr;25(2):306-321. doi: 10.1212/CON.0000000000000707. PMID: 30921011
Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshé SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM
Epilepsia 2017 Apr;58(4):522-530. Epub 2017 Mar 8 doi: 10.1111/epi.13670. PMID: 28276060
Berg AT, Berkovic SF, Brodie MJ, Buchhalter J, Cross JH, van Emde Boas W, Engel J, French J, Glauser TA, Mathern GW, Moshé SL, Nordli D, Plouin P, Scheffer IE
Epilepsia 2010 Apr;51(4):676-85. Epub 2010 Feb 26 doi: 10.1111/j.1528-1167.2010.02522.x. PMID: 20196795

Therapy

Yamamoto T, Gil-Nagel A, Wheless JW, Kim JH, Wechsler RT
Epilepsy Behav 2022 Nov;136:108885. Epub 2022 Sep 21 doi: 10.1016/j.yebeh.2022.108885. PMID: 36150304
Knight EMP, Amin S, Bahi-Buisson N, Benke TA, Cross JH, Demarest ST, Olson HE, Specchio N, Fleming TR, Aimetti AA, Gasior M, Devinsky O; Marigold Trial Group
Lancet Neurol 2022 May;21(5):417-427. doi: 10.1016/S1474-4422(22)00077-1. PMID: 35429480
Chung SS, French JA, Kowalski J, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Mizne S, Kamin M
Neurology 2020 Jun 2;94(22):e2311-e2322. Epub 2020 May 14 doi: 10.1212/WNL.0000000000009530. PMID: 32409485Free PMC Article
Krauss GL, Klein P, Brandt C, Lee SK, Milanov I, Milovanovic M, Steinhoff BJ, Kamin M
Lancet Neurol 2020 Jan;19(1):38-48. Epub 2019 Nov 14 doi: 10.1016/S1474-4422(19)30399-0. PMID: 31734103
Rugg-Gunn F, Miserocchi A, McEvoy A
Pract Neurol 2020 Feb;20(1):4-14. Epub 2019 Aug 16 doi: 10.1136/practneurol-2019-002192. PMID: 31420415

Prognosis

Salanova V, Sperling MR, Gross RE, Irwin CP, Vollhaber JA, Giftakis JE, Fisher RS; SANTÉ Study Group
Epilepsia 2021 Jun;62(6):1306-1317. Epub 2021 Apr 8 doi: 10.1111/epi.16895. PMID: 33830503
Levine JM, Ahsan N, Ho E, Santoro JD
Mult Scler Relat Disord 2020 Aug;43:102194. Epub 2020 May 15 doi: 10.1016/j.msard.2020.102194. PMID: 32426208Free PMC Article
Specchio N, Pietrafusa N
Dev Med Child Neurol 2020 Aug;62(8):897-905. Epub 2020 May 5 doi: 10.1111/dmcn.14553. PMID: 32372459
Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, Oommen K, Osorio I, Nazzaro J, Labar D, Kaplitt M, Sperling M, Sandok E, Neal J, Handforth A, Stern J, DeSalles A, Chung S, Shetter A, Bergen D, Bakay R, Henderson J, French J, Baltuch G, Rosenfeld W, Youkilis A, Marks W, Garcia P, Barbaro N, Fountain N, Bazil C, Goodman R, McKhann G, Babu Krishnamurthy K, Papavassiliou S, Epstein C, Pollard J, Tonder L, Grebin J, Coffey R, Graves N; SANTE Study Group
Epilepsia 2010 May;51(5):899-908. Epub 2010 Mar 17 doi: 10.1111/j.1528-1167.2010.02536.x. PMID: 20331461
Brenner RP
Epilepsia 2002;43 Suppl 3:103-13. doi: 10.1046/j.1528-1157.43.s.3.9.x. PMID: 12060012

Clinical prediction guides

Villani F, Cianci V, Di Bonaventura C, Di Gennaro G, Galimberti CA, Guerrini R, La Neve A, Mecarelli O, Pietrafusa N, Specchio N, Vigevano F, Perucca E
Expert Rev Neurother 2022 Nov-Dec;22(11-12):935-940. Epub 2023 Jan 24 doi: 10.1080/14737175.2023.2171291. PMID: 36662573
Kaaden T, Madlener M, Angstwurm K, Bien CG, Bogarin Y, Doppler K, Finke A, Gerner ST, Reimann G, Häusler M, Handreka R, Hellwig K, Kaufmann M, Kellinghaus C, Koertvelyessy P, Kraft A, Lewerenz J, Menge T, Paliantonis A, von Podewils F, Prüss H, Rauer S, Ringelstein M, Rostásy K, Schirotzek I, Schwabe J, Sokolowski P, Suesse M, Sühs KW, Surges R, Tauber SC, Thaler F, Bergh FT, Urbanek C, Wandinger KP, Wildemann B, Mues S, Zettl U, Leypoldt F, Melzer N, Geis C, Malter M, Kunze A; and the Generate study group
Neurol Neuroimmunol Neuroinflamm 2022 Nov;9(6) Epub 2022 Oct 20 doi: 10.1212/NXI.0000000000200034. PMID: 36266054Free PMC Article
Montalvo M, Khattak JF, Redenbaugh V, Britton J, Sanchez CV, Datta A, Tillema JM, Chen J, McKeon A, Pittock SJ, Flanagan EP, Dubey D
Epilepsia 2022 Dec;63(12):3180-3191. Epub 2022 Oct 14 doi: 10.1111/epi.17424. PMID: 36168809Free PMC Article
Khoo A, de Tisi J, Mannan S, O'Keeffe AG, Sander JW, Duncan JS
Epilepsia 2021 Dec;62(12):2909-2919. Epub 2021 Sep 23 doi: 10.1111/epi.17083. PMID: 34558079
Donos C, Maliia MD, Dümpelmann M, Schulze-Bonhage A
Epilepsia 2018 Mar;59(3):650-660. Epub 2018 Jan 11 doi: 10.1111/epi.13997. PMID: 29322500

Recent systematic reviews

Lavu A, Aboulatta L, Abou-Setta AM, Aloud B, Askin N, Rabbani R, Shouman W, Zarychanski R, Eltonsy S
Seizure 2022 Nov;102:54-60. Epub 2022 Sep 29 doi: 10.1016/j.seizure.2022.09.020. PMID: 36206645
Casanovas Ortega M, Bruno E, Richardson MP
Epilepsy Behav 2022 Sep;134:108864. Epub 2022 Aug 8 doi: 10.1016/j.yebeh.2022.108864. PMID: 35952508
Cutillo G, Tolba H, Hirsch LJ
Epilepsy Behav 2021 Apr;117:107815. Epub 2021 Feb 26 doi: 10.1016/j.yebeh.2021.107815. PMID: 33640562
Christie H, D'Souza W, Cook M, Seneviratne U
Epilepsy Behav 2021 Mar;116:107769. Epub 2021 Feb 5 doi: 10.1016/j.yebeh.2021.107769. PMID: 33556863
Beh SMJ, Cook MJ, D'Souza WJ
Epilepsy Behav 2016 Jul;60:33-41. Epub 2016 May 10 doi: 10.1016/j.yebeh.2016.04.015. PMID: 27176882

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