Renal tubular epithelial cell sloughing

MedGen UID:: 1712011
•Concept ID:: C5397619
•: Finding

HPO:	HP:0032597

Definition

At least one free floating cell in the tubular lumen without attachment to adjacent cells or basement membrane in a tubular cross section without detachment. These cells must not aggregate into a tubular shape and completely fill the lumen, if so, it should be classified as a cast. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRenal tubular epithelial cell sloughing

Abnormality of the upper urinary tract
- Abnormality of the kidney
  - Abnormal renal morphology
    - Abnormal nephron morphology
      - Abnormal renal tubule morphology
        Abnormal renal tubular epithelial morphology
        Renal tubular epithelial cell sloughing

Recent clinical studies

Etiology

Renal Histopathologic Findings Associated With Severity of Clinical Acute Kidney Injury.

Kudose S, Hoshi M, Jain S, Gaut JP
Am J Surg Pathol 2018 May;42(5):625-635. doi: 10.1097/PAS.0000000000001028. PMID: 29537990

Protective effect of truncated Na+/K+-ATPase β on ischemia/reperfusion-induced renal injury in rats.

Gong H, Sun J, Xue W, Tian P, Ding X, Yan H, Li Y, Zheng J
Exp Biol Med (Maywood) 2014 Jun;239(6):677-85. doi: 10.1177/1535370213517613. PMID: 24737734

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Diagnosis

Cholemic Nephrosis: An Autopsy Study of a Forgotten Entity.

Priyaa V, Srinivas BH, Gochhait D, Ganesh RN, Badhe BA, Priyamvada PS, Amalnath D, DAS S, Shaha KK
Turk Patoloji Derg 2021;37(3):212-218. doi: 10.5146/tjpath.2021.01532. PMID: 34514566 Free PMC Article

Renal Histopathologic Findings Associated With Severity of Clinical Acute Kidney Injury.

Kudose S, Hoshi M, Jain S, Gaut JP
Am J Surg Pathol 2018 May;42(5):625-635. doi: 10.1097/PAS.0000000000001028. PMID: 29537990

Localization of Hantaan viral envelope glycoproteins by monoclonal antibodies in renal tissues from patients with Korean hemorrhagic fever H.

Kim S, Kang ET, Kim YG, Han JS, Lee JS, Kim YI, Hall WC, Dalrymple JM, Peters CJ
Am J Clin Pathol 1993 Oct;100(4):398-403. doi: 10.1093/ajcp/100.4.398. PMID: 7692720

See all (3)