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Abnormal renal tubular epithelial morphology

MedGen UID:
1717573
Concept ID:
C5397621
Anatomical Abnormality
HPO: HP:0032599

Definition

Any structural anomaly of the renal tubular epithelial cells (RTEC), a layer of cells in the outer layer of the renal tubule. These cells play a role in the absorption of substances such as glucose and amino from the primary urine. [from HPO]

Professional guidelines

PubMed

Li T, Surendran K, Zawaideh MA, Mathew S, Hruska KA
Curr Opin Nephrol Hypertens 2004 Jul;13(4):417-22. doi: 10.1097/01.mnh.0000133974.24935.fe. PMID: 15199292

Recent clinical studies

Etiology

Guo W, Li H, Li Y, Kong W
Biomed Pharmacother 2023 Sep;165:115025. Epub 2023 Jun 28 doi: 10.1016/j.biopha.2023.115025. PMID: 37385209
Tang Z, Li T, Dai H, Feng C, Xie X, Peng F, Lan G, Yu S, Wang Y, Fang C, Nie M, Yuan X, Tang X, Jiang X, Zhu X, Fan Y, Peng J, Sun S, Zhong M, Zhang H, Peng L
Front Immunol 2022;13:979983. Epub 2022 Aug 19 doi: 10.3389/fimmu.2022.979983. PMID: 36059468Free PMC Article
Cayci FS, Aydin Z, Aygar IS, Avci B, Inozu M, Aksoy OY, Bayrakci US
Clin Nephrol 2021 Jun;95(6):332-337. doi: 10.5414/CN110402. PMID: 33704056
Balakumar P, Alqahtani A, Khan NA, Mahadevan N, Dhanaraj SA
Pharmacol Res 2020 Nov;161:105209. Epub 2020 Sep 23 doi: 10.1016/j.phrs.2020.105209. PMID: 32979505
Kanagasundaram NS
Ann Clin Biochem 2015 Mar;52(Pt 2):193-205. Epub 2014 Oct 7 doi: 10.1177/0004563214556820. PMID: 25293591

Diagnosis

Tang Z, Li T, Dai H, Feng C, Xie X, Peng F, Lan G, Yu S, Wang Y, Fang C, Nie M, Yuan X, Tang X, Jiang X, Zhu X, Fan Y, Peng J, Sun S, Zhong M, Zhang H, Peng L
Front Immunol 2022;13:979983. Epub 2022 Aug 19 doi: 10.3389/fimmu.2022.979983. PMID: 36059468Free PMC Article
Cayci FS, Aydin Z, Aygar IS, Avci B, Inozu M, Aksoy OY, Bayrakci US
Clin Nephrol 2021 Jun;95(6):332-337. doi: 10.5414/CN110402. PMID: 33704056
Wang WG, Sun WX, Gao BS, Lian X, Zhou HL
Curr Protein Pept Sci 2017;18(12):1224-1231. doi: 10.2174/1389203717666160915162238. PMID: 27634440
Lopez-Beltran A, Scarpelli M, Montironi R, Kirkali Z
Eur Urol 2006 May;49(5):798-805. Epub 2006 Jan 17 doi: 10.1016/j.eururo.2005.11.035. PMID: 16442207
Dressler GR, Woolf AS
Int J Dev Biol 1999;43(5):463-8. PMID: 10535325

Therapy

Wang B, Yang LN, Yang LT, Liang Y, Guo F, Fu P, Ma L
Acta Pharmacol Sin 2024 Jan;45(1):150-165. Epub 2023 Sep 11 doi: 10.1038/s41401-023-01156-w. PMID: 37696989Free PMC Article
Guo W, Li H, Li Y, Kong W
Biomed Pharmacother 2023 Sep;165:115025. Epub 2023 Jun 28 doi: 10.1016/j.biopha.2023.115025. PMID: 37385209
Li K, Gao L, Zhou S, Ma YR, Xiao X, Jiang Q, Kang ZH, Liu ML, Liu TX
Mol Cell Biochem 2023 Mar;478(3):651-663. Epub 2022 Aug 24 doi: 10.1007/s11010-022-04540-y. PMID: 36001204
Tang Z, Li T, Dai H, Feng C, Xie X, Peng F, Lan G, Yu S, Wang Y, Fang C, Nie M, Yuan X, Tang X, Jiang X, Zhu X, Fan Y, Peng J, Sun S, Zhong M, Zhang H, Peng L
Front Immunol 2022;13:979983. Epub 2022 Aug 19 doi: 10.3389/fimmu.2022.979983. PMID: 36059468Free PMC Article
Zhu Y, Cui H, Lv J, Liang H, Zheng Y, Wang S, Wang M, Wang H, Ye F
Sci Rep 2019 Dec 19;9(1):19450. doi: 10.1038/s41598-019-55550-8. PMID: 31857626Free PMC Article

Prognosis

Tang Z, Li T, Dai H, Feng C, Xie X, Peng F, Lan G, Yu S, Wang Y, Fang C, Nie M, Yuan X, Tang X, Jiang X, Zhu X, Fan Y, Peng J, Sun S, Zhong M, Zhang H, Peng L
Front Immunol 2022;13:979983. Epub 2022 Aug 19 doi: 10.3389/fimmu.2022.979983. PMID: 36059468Free PMC Article
Caza T, Wijewardena C, Al-Rabadi L, Perl A
Transl Res 2022 Jul;245:55-81. Epub 2022 Mar 12 doi: 10.1016/j.trsl.2022.03.004. PMID: 35288362Free PMC Article
Cayci FS, Aydin Z, Aygar IS, Avci B, Inozu M, Aksoy OY, Bayrakci US
Clin Nephrol 2021 Jun;95(6):332-337. doi: 10.5414/CN110402. PMID: 33704056
Wang WG, Sun WX, Gao BS, Lian X, Zhou HL
Curr Protein Pept Sci 2017;18(12):1224-1231. doi: 10.2174/1389203717666160915162238. PMID: 27634440
Anders HJ, Ryu M
Kidney Int 2011 Nov;80(9):915-925. Epub 2011 Aug 3 doi: 10.1038/ki.2011.217. PMID: 21814171

Clinical prediction guides

Caza T, Wijewardena C, Al-Rabadi L, Perl A
Transl Res 2022 Jul;245:55-81. Epub 2022 Mar 12 doi: 10.1016/j.trsl.2022.03.004. PMID: 35288362Free PMC Article
Wen Y, Chen J, Liu L, Guo G, Zeng Y, Zhang Y, Zeng Z, Wang Z, Peng X, Liang J
J Recept Signal Transduct Res 2020 Apr;40(2):141-147. Epub 2020 Jan 31 doi: 10.1080/10799893.2020.1719518. PMID: 32000560
Ferrè S, Igarashi P
Pediatr Nephrol 2019 Aug;34(8):1325-1335. Epub 2018 Jul 1 doi: 10.1007/s00467-018-3990-7. PMID: 29961928Free PMC Article
Lee EJ
Adv Exp Med Biol 2016;933:25-34. doi: 10.1007/978-981-10-2041-4_3. PMID: 27730432
Kanagasundaram NS
Ann Clin Biochem 2015 Mar;52(Pt 2):193-205. Epub 2014 Oct 7 doi: 10.1177/0004563214556820. PMID: 25293591

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