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Focal aware autonomic seizure

MedGen UID:
1713511
•Concept ID:
C5397750
•
Disease or Syndrome
Synonyms: Focal autonomic seizures without altered responsiveness; Focal onset aware autonomic epileptic seizure; Focal onset aware autonomic seizure; Focal-onset aware autonomic epileptic seizure; Localised autonomic seizures without altered responsiveness; Localized autonomic seizures without altered responsiveness; Partial autonomic seizures without altered responsiveness
SNOMED CT: Focal onset aware autonomic epileptic seizure (7454002); Focal-onset aware autonomic epileptic seizure (7454002); Focal aware autonomic seizure (7454002); Focal onset aware autonomic seizure (7454002)
 
HPO: HP:0032740

Definition

A focal aware autonomic seizure has an initial manifestation pertaining to autonomic nervous system function, which may be objective (for example, pupillary dilation) or subjective (for example, nausea). As a type of focal aware seizure, awareness is retained throughout. [from HPO]

Professional guidelines

PubMed

Early identification of seizure freedom with medical treatment in patients with mesial temporal lobe epilepsy and hippocampal sclerosis.
Cheval M, Houot M, Chastan N, Szurhaj W, Marchal C, Catenoix H, Valton L, Gavaret M, Herlin B, Biraben A, Lagarde S, Mazzola L, Minotti L, Maillard L, Dupont S
J Neurol 2023 May;270(5):2715-2723. Epub 2023 Feb 10 doi: 10.1007/s00415-023-11603-7. PMID: 36763175
Effects of Chronic Carbamazepine Treatment on the ECG in Patients with Focal Seizures.
Sathyaprabha TN, Koot LAM, Hermans BHM, Adoor M, Sinha S, Kramer BW, Raju TR, Satishchandra P, Delhaas T
Clin Drug Investig 2018 Sep;38(9):845-851. doi: 10.1007/s40261-018-0677-6. PMID: 30047104Free PMC Article

Recent clinical studies

Etiology

Posterior Cingulate Epilepsy: A Systematic Review.
Pepin C, Brochu K, Lessard-Bonaventure P, Nguyen DK, Martineau L
J Clin Neurophysiol 2023 Sep 1;40(6):507-515. Epub 2023 Mar 15 doi: 10.1097/WNP.0000000000000975. PMID: 36930208
Comparison of 2017 ILAE and Semiological seizure classifications before and after video-EEG monitoring in childhood epilepsy.
Ucar HK, Arhan E, Aydin K, Hirfanoglu T, Serdaroglu A
Eur Rev Med Pharmacol Sci 2022 Apr;26(7):2343-2352. doi: 10.26355/eurrev_202204_28463. PMID: 35442488
Association Between Semiology and Anatomo-functional Localization in Patients With Cingulate Epilepsy: A Cohort Study.
Pelliccia V, Avanzini P, Rizzi M, Caruana F, Tassi L, Francione S, Gozzo F, Mariani V, d'Orio P, Castana L, Mai R, Terzaghi M, Nobili L, Sartori I
Neurology 2022 May 31;98(22):e2211-e2223. Epub 2022 Feb 21 doi: 10.1212/WNL.0000000000200145. PMID: 35190463
Which seizure elements do patients memorize? A comparison of history and seizure documentation.
Mielke H, Meissner S, Wagner K, Joos A, Schulze-Bonhage A
Epilepsia 2020 Jul;61(7):1365-1375. Epub 2020 Jun 9 doi: 10.1111/epi.16550. PMID: 32515852
Electroclinical features of seizures associated with autoimmune encephalitis.
Steriade C, Moosa ANV, Hantus S, Prayson RA, Alexopoulos A, Rae-Grant A
Seizure 2018 Aug;60:198-204. Epub 2018 Jun 28 doi: 10.1016/j.seizure.2018.06.021. PMID: 30031297

Diagnosis

Posterior Cingulate Epilepsy: A Systematic Review.
Pepin C, Brochu K, Lessard-Bonaventure P, Nguyen DK, Martineau L
J Clin Neurophysiol 2023 Sep 1;40(6):507-515. Epub 2023 Mar 15 doi: 10.1097/WNP.0000000000000975. PMID: 36930208
Comparison of 2017 ILAE and Semiological seizure classifications before and after video-EEG monitoring in childhood epilepsy.
Ucar HK, Arhan E, Aydin K, Hirfanoglu T, Serdaroglu A
Eur Rev Med Pharmacol Sci 2022 Apr;26(7):2343-2352. doi: 10.26355/eurrev_202204_28463. PMID: 35442488
Which seizure elements do patients memorize? A comparison of history and seizure documentation.
Mielke H, Meissner S, Wagner K, Joos A, Schulze-Bonhage A
Epilepsia 2020 Jul;61(7):1365-1375. Epub 2020 Jun 9 doi: 10.1111/epi.16550. PMID: 32515852
Misdiagnosis and pitfalls in Panayiotopoulos syndrome.
Graziosi A, Pellegrino N, Di Stefano V, Raucci U, Luchetti A, Parisi P
Epilepsy Behav 2019 Sep;98(Pt A):124-128. Epub 2019 Jul 29 doi: 10.1016/j.yebeh.2019.07.016. PMID: 31369969
Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology.
Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshé SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM
Epilepsia 2017 Apr;58(4):522-530. Epub 2017 Mar 8 doi: 10.1111/epi.13670. PMID: 28276060

Therapy

Seizure detection using heart rate variability: A prospective validation study.
Jeppesen J, Fuglsang-Frederiksen A, Johansen P, Christensen J, Wüstenhagen S, Tankisi H, Qerama E, Beniczky S
Epilepsia 2020 Nov;61 Suppl 1:S41-S46. Epub 2020 May 7 doi: 10.1111/epi.16511. PMID: 32378197
Epilepsy in LAMA2-related muscular dystrophy: An electro-clinico-radiological characterization.
Natera-de Benito D, Muchart J, Itzep D, Ortez C, González-Quereda L, Gallano P, Ramirez A, Aparicio J, Domínguez-Carral J, Carrera-García L, Expósito-Escudero J, Pardo Cardozo N, Cuadras D, Codina A, Jou C, Jimenez-Mallebrera C, Palau F, Colomer J, Arzimanoglou A, Nascimento A, San Antonio-Arce V
Epilepsia 2020 May;61(5):971-983. Epub 2020 Apr 8 doi: 10.1111/epi.16493. PMID: 32266982
Ictal Video-Electroencephalography Findings in Bathing Seizures: Two New Cases and Review of the Literature.
Mosquera-Gorostidi A, Azcona-Ganuza G, Yoldi-Petri ME, García de Gurtubay I, Aguilera-Albesa S
Pediatr Neurol 2019 Oct;99:76-81. Epub 2019 Apr 26 doi: 10.1016/j.pediatrneurol.2019.04.017. PMID: 31272783
Electroclinical features of seizures associated with autoimmune encephalitis.
Steriade C, Moosa ANV, Hantus S, Prayson RA, Alexopoulos A, Rae-Grant A
Seizure 2018 Aug;60:198-204. Epub 2018 Jun 28 doi: 10.1016/j.seizure.2018.06.021. PMID: 30031297
The epileptology of Koolen-de Vries syndrome: Electro-clinico-radiologic findings in 31 patients.
Myers KA, Mandelstam SA, Ramantani G, Rushing EJ, de Vries BB, Koolen DA, Scheffer IE
Epilepsia 2017 Jun;58(6):1085-1094. Epub 2017 Apr 25 doi: 10.1111/epi.13746. PMID: 28440867

Prognosis

Early identification of seizure freedom with medical treatment in patients with mesial temporal lobe epilepsy and hippocampal sclerosis.
Cheval M, Houot M, Chastan N, Szurhaj W, Marchal C, Catenoix H, Valton L, Gavaret M, Herlin B, Biraben A, Lagarde S, Mazzola L, Minotti L, Maillard L, Dupont S
J Neurol 2023 May;270(5):2715-2723. Epub 2023 Feb 10 doi: 10.1007/s00415-023-11603-7. PMID: 36763175
Twenty-four-hour patterns in electrodermal activity recordings of patients with and without epileptic seizures.
Vieluf S, Amengual-Gual M, Zhang B, El Atrache R, Ufongene C, Jackson MC, Branch S, Reinsberger C, Loddenkemper T
Epilepsia 2021 Apr;62(4):960-972. Epub 2021 Feb 23 doi: 10.1111/epi.16843. PMID: 33619751
Epilepsy in LAMA2-related muscular dystrophy: An electro-clinico-radiological characterization.
Natera-de Benito D, Muchart J, Itzep D, Ortez C, González-Quereda L, Gallano P, Ramirez A, Aparicio J, Domínguez-Carral J, Carrera-García L, Expósito-Escudero J, Pardo Cardozo N, Cuadras D, Codina A, Jou C, Jimenez-Mallebrera C, Palau F, Colomer J, Arzimanoglou A, Nascimento A, San Antonio-Arce V
Epilepsia 2020 May;61(5):971-983. Epub 2020 Apr 8 doi: 10.1111/epi.16493. PMID: 32266982
Electroclinical features of seizures associated with autoimmune encephalitis.
Steriade C, Moosa ANV, Hantus S, Prayson RA, Alexopoulos A, Rae-Grant A
Seizure 2018 Aug;60:198-204. Epub 2018 Jun 28 doi: 10.1016/j.seizure.2018.06.021. PMID: 30031297
Neurological manifestations of acute intermittent porphyria.
Pischik E, Kauppinen R
Cell Mol Biol (Noisy-le-grand) 2009 Feb 16;55(1):72-83. PMID: 19268005

Clinical prediction guides

Epilepsy in Children With Congenital Heart Disease: Risk Factors and Characteristic Presentations.
Shibata T, Kondo M, Fukushima Y, Akiyama M, Akiyama T, Morooka T, Baba K, Ohtsuki S, Tsukahara H, Kasahara S, Kobayashi K
Pediatr Neurol 2023 Oct;147:28-35. Epub 2023 Jul 13 doi: 10.1016/j.pediatrneurol.2023.07.004. PMID: 37542972
Posterior Cingulate Epilepsy: A Systematic Review.
Pepin C, Brochu K, Lessard-Bonaventure P, Nguyen DK, Martineau L
J Clin Neurophysiol 2023 Sep 1;40(6):507-515. Epub 2023 Mar 15 doi: 10.1097/WNP.0000000000000975. PMID: 36930208
Twenty-four-hour patterns in electrodermal activity recordings of patients with and without epileptic seizures.
Vieluf S, Amengual-Gual M, Zhang B, El Atrache R, Ufongene C, Jackson MC, Branch S, Reinsberger C, Loddenkemper T
Epilepsia 2021 Apr;62(4):960-972. Epub 2021 Feb 23 doi: 10.1111/epi.16843. PMID: 33619751
Epilepsy in LAMA2-related muscular dystrophy: An electro-clinico-radiological characterization.
Natera-de Benito D, Muchart J, Itzep D, Ortez C, González-Quereda L, Gallano P, Ramirez A, Aparicio J, Domínguez-Carral J, Carrera-García L, Expósito-Escudero J, Pardo Cardozo N, Cuadras D, Codina A, Jou C, Jimenez-Mallebrera C, Palau F, Colomer J, Arzimanoglou A, Nascimento A, San Antonio-Arce V
Epilepsia 2020 May;61(5):971-983. Epub 2020 Apr 8 doi: 10.1111/epi.16493. PMID: 32266982
The epileptology of Koolen-de Vries syndrome: Electro-clinico-radiologic findings in 31 patients.
Myers KA, Mandelstam SA, Ramantani G, Rushing EJ, de Vries BB, Koolen DA, Scheffer IE
Epilepsia 2017 Jun;58(6):1085-1094. Epub 2017 Apr 25 doi: 10.1111/epi.13746. PMID: 28440867

Recent systematic reviews

Posterior Cingulate Epilepsy: A Systematic Review.
Pepin C, Brochu K, Lessard-Bonaventure P, Nguyen DK, Martineau L
J Clin Neurophysiol 2023 Sep 1;40(6):507-515. Epub 2023 Mar 15 doi: 10.1097/WNP.0000000000000975. PMID: 36930208

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